ENKRIPSI PESAN TEKS MENGGUNAKAN GABUNGAN ALGORITMA HILL CIPHER DAN RSA

Saat ini, teknologi yang sudah berkembang dengan sangat pesat menjadi kebutuhan primer bagi kehidupan manusia, untuk membantu kebutuhan sehari-hari seperti berkomunikasi, bertukar informasi, untuk hiburan dan kebutuhan manusia lainnya. Namun, ada juga pihak yang mencoba untuk menyalahgunakan perkembangan teknologi untuk mengakses data seseorang yang bersifat pribadi. Contoh nya seperti yang terjadi pada mahasiswa pada umumnya. mereka sering menyimpan data yang bersifat pribadi dan rahasia di dalam laptop.Akan berbahaya jika di akses oleh orang yang tidak bertanggung jawab. Kriptografi dalam pengenkripsiannya dapat mengubah teks menjadi cipher yang tidak di mengerti oleh orang lain. Dengan menggunakan kombinasi algoritma Hill cipher dan RSA, hasil cipherteks membuat data tidak mudah di ketahui oleh orang lain

Analisis derajat desentralisasi dan kemandirian PAD serta hubungannya dengan produktivitas belanja daerah di Kota Jambi

Penelitian ini bertujuan untuk menganalisis (1) derajat desentralisasi fiskal di Kota Jambi, (2 derajat kemandirian fiskal di Kota Jambi, (3) produktivitas belanja daerah di Kota Jambi, (4) tingkat keeratan hubungan antara derajat desentralisasi dan kemandirian fiskal dengan produktivitas belanja daerah di Kota Jambi. Data yang digunakan adalah data sekunder berupa runtun waktu (time series) dari Tahun 2001-2013 mencakup (1) realisasi Anggaran Pendapatan dan Belanja Daerah (APBD) Kota Jambi, (2) realisasi Produk Domestik Regional Bruto (PDRB) Kota Jambi. Alat analisis yang digunakan dalam penelitian ini, yaitu analisis Derajat Desentralisasi Fiskal (DDF), analisis Derajat Kemandirian Fiskal (DKF), analisis Produktivitas Belanja Daerah (PBD), serta analisis Korelasi Pearson. Hasil analisis menunjukkan bahwa derajat desentralisasi fiskal, kemandirian fiskal dan produktivitas belanja daerah di Kota Jambi masih terkategori lemah. Selanjutnya terdapat korelasi positif yang nyata antara derajat desentralisasi dan kemandirian fiskal dengan produktivitas belanja daerah di Kota Jambi

MENJALIN KERJASAMA DENGAN PEMUDA KARANGTARUNA UNTUK MENINGKATKAN KUALITAS LINGKUNGAN

Rendahnya kesadaran masyarakat Kelurahan Putat Jaya (eks-lokalisasi Dolly) RT 03, Kota Surabaya akan pentingnya pengelolaan sampah yang ditandai dengan siklus pembuangan sampah selama lima hari sekali menyebabkan kualitas lingkungan yang buruk. Hal ini juga diperparah dengan kualitas tempat sampah yang kurang memadai sehingga banyak sampah menumpuk dan berserakan di luar tempat sampah dan wilayah tersebut terkesan kumuh. Sebuah kegiatan untuk meningkatkan kesadaran masyarakat akan pentingnya pengelolaan sampah perlu dilaksanakan sehingga mahasiswa Universitas Kristen Petra bekerja sama dengan pemuda karangtaruna melaksanakan kegiatan service learning. Diharapkan melalui kegiatan ini, masyarakat dapat meningkatkan kesadaran akan pengelolaan sampah agar bisa menciptakan lingkungan yang bersih dan sehat. Di akhir acara diadakan makan bersama untuk mempererat hubungan dengan masyarakat. Dari survei yang dilakukan mengindikasikan 98% responden menyatakan bahwa kerjasama antara mahasiswa dan masyarakat khususnya pemuda karangtaruna pada rangkaian kegiatan service learning telah berjalan dengan baik. 100% responden juga merasa terbantu dengan diadakannya kegiatan ini dan mengharapkan agar kegiatan ini dapat terus dilakukan kembali

MENJALIN KERJASAMA DENGAN PEMUDA KARANGTARUNA UNTUK MENINGKATKAN KUALITAS LINGKUNGAN

Rendahnya kesadaran masyarakat kelurahan Putat Jaya (Ekslokalisasi Dolly) RT 03, kota Surabaya akan pentingnya pengelolaan sampah yang ditandai dengan siklus pembuangan sampah selama 5 hari sekali menyebabkan kualitas lingkungan yang buruk. Hal ini juga diperparah dengan kualitas tempat sampah yang kurang memadai, sehingga banyak sampah menumpuk dan berserakan di luar tempat sampah sehingga wilayah tersebut terkesan kumuh. Sebuah kegiatan untuk meningkatkan kesadaran masyarakat akan pentingnya pengelolaan sampah perlu dilaksanakan, sehingga mahasiswa Universitas Kristen Petra bekerja sama dengan pemuda Karang taruna melaksanakan kegiatan Service Learning. Diharapkan melalui kegiatan ini, masyarakat dapat meningkatkan kesadaran akan pengelolaan sampah agar bisa menciptakan lingkungan yang bersih dan sehat. Di akhir acara diadakan makan bersama untuk mempererat hubungan dengan masyarakat. Dari survey yang dilakukan mengindikasikan 98% responden menyatakan bahwa kerjasama antara mahasiswa dan masyarakat khususnya pemuda karangtaruna pada rangkaian kegiatan Service Learning telah berjalan dengan baik. 100 % responden juga merasa terbantu dengan diadakannya kegiatan ini dan mengharapkan agar kegiatan ini dapat terus dilakukan kembali

VEGF Gene Expression in Adult Human Thymus Fat: A Correlative Study with Hypoxic Induced Factor and Cyclooxigenase-2

UNLABELLED:It is well known that the adult human thymus degenerates into fat tissue; however, it has never been considered as a potential source of angiogenic factors. Recently, we have described that this fat (TAT) produces angiogenic factors and induces human endothelial cell proliferation and migration, indicating its potential angiogenic properties. DESIGN:Adult thymus fat and subcutaneous adipose tissue specimens were obtained from 28 patients undergoing cardiac surgery, making this tissue readily available as a prime source of adipose tissue. We focused our investigation on determining VEGF gene expression and characterizing the different genes, mediators of inflammation and adipogenesis, and which are known to play a relevant role in angiogenesis regulation. RESULTS:We found that VEGF-A was the isoform most expressed in TAT. This expression was accompanied by an upregulation of HIF-1alpha, COX-2 and HO-1 proteins, and by increased HIF-1 DNA binding activity, compared to SAT. Furthermore, we observed that TAT contains a high percentage of mature adipocytes, 0.25% of macrophage cells, 15% of endothelial cells and a very low percentage of thymocyte cells, suggesting the cellular variability of TAT, which could explain the differences in gene expression observed in TAT. Subsequently, we showed that the expression of genes known as adipogenic mediators, including PPARgamma1/gamma2, FABP-4 and adiponectin was similar in both TAT and SAT. Moreover the expression of these latter genes presented a significantly positive correlation with VEGF, suggesting the potential association between VEGF and the generation of adipose tissue in adult thymus. CONCLUSION:Here we suggest that this fat has a potential angiogenic function related to ongoing adipogenesis, which substitutes immune functions within the adult thymus. The expression of VEGF seems to be associated with COX-2, HO-1 and adipogenesis related genes, suggesting the importance that this new fat has acquired in research in relation to adipogenesis and angiogenesis

655MO Quality of life in patients with p16+ oropharyngeal cancer receiving accelerated radiotherapy (RT) with either cisplatin or cetuximab in NRG/RTOG 1016

Background: This phase 3 randomized non-inferiority de-escalation trial compared cetuximab (cetux) vs cisplatin (cis), concurrent with accelerated RT 70 Gy/6 weeks, in p16+ oropharyngeal cancer (OPC). Quality of life (QOL) was an important secondary endpoint. Methods: EORTC QLQ-C30/HN35 was completed at baseline, end of treatment, 3, 6, and 12 months post. The substudy aimed for 400 eligible patients. We report completion rates and compare by arm for change from baseline in each domain (0.05 two-sided alpha and MID of 10 points) using linear mixed models. Results: Consent was 91% (381/419 offered substudy); 6 protocol deviations excluded (n=375). No significant differences in patient/tumor characteristics were found by participation status. Completion rates (%) at the 5 times did not differ by arm (cis/cetux): 92/94, 74/77, 76/81, 76/81, and 73/74. The swallowing domain of HN35 (previously reported) did not differ significantly by arm. No significant difference was seen by arm for the 6-mo change from baseline on any domain. At end of RT (only), dry mouth was significantly worse for RT+cetux. At end of treatment, all domains showed statistically and clinically significant mean worsening across both arms except Emotional Functioning, Dyspnea, Diarrhea, and Teeth. Most domains returned within 10 points of baseline by 6 mo, with the following maintaining significant impairment: Senses (taste/smell), Social Eating, Opening Mouth, Dry Mouth, Sticky Saliva. At 12 mo post-treatment, worsening from baseline persisted for Senses, Dry Mouth, Sticky Saliva, and Weight Gain. Pain Killer use improved significantly from baseline to 3, 6, and 12 mo. Conclusions: Although replacing RT+cis with RT+cetux did not benefit QOL, this study has confirmed the responsiveness of EORTC QLQ-C30/HN35 to the effects of concurrent systemic/RT for OPC. Dry Mouth, Sticky Saliva, and Senses showed large, significant, and persistent impairments, and remain worthwhile targets for future de-escalation efforts. Domains related to eating (Swallowing, Appetite, Nutritional Supplements, Social Eating, Weight Loss) did not show sustained significant impairment on this instrument in this study. Clinical trial identification: NCT01302834

RTOG/NRG 1115 Quality of Life of Phase III Dose Escalated Radiation Therapy (RT) and Standard Androgen Deprivation Therapy (ADT) with GnRH Agonist vs. Dose Escalated RT and ADT with GnRH Agonist and Orteronel (TAK-700) for Men with High-Risk Prostate

Purpose/Objective(s): Quality of life (QOL) was assessed with the hypothesis that QOL and fatigue scores would not differ significantly between the ADT + RT (Arm A) and the experimental group receiving ADT + RT + oreteronel (Arm B). Materials/Methods: In both arms, ADT with GnRH agonist was given for 24 mos, and dose escalated RT started 8-10 wks after initiation of ADT. In Arm B, oreteronel was given BID for 24 mos. QOL was measured with Expanded Prostate Cancer Index Composite (EPIC) and EQ-5D global QOL assessment. EPIC has 4 domains: bowel, urinary, sexual, and hormonal. EQ-5D index score was calculated using health states obtained from 5 dimensions, and a visual analog score (VAS). For EPIC, EQ-5D index and VAS, higher scores indicate better QOL. Fatigue was measured by the 7-item Patient-Reported Outcome Measurement Information System (PROMIS) short form. Total score is standardized into a T-score with mean of 50 and standard deviation of 10 with higher score representing more fatigue. Change scores, calculated as follow-up minus baseline, were compared between arms. Longitudinal analysis using repeated measures mixed effects models was conducted (prior to ADT [baseline], one wk prior to starting RT, last wk of RT, and 1 and 2.5 yrs after initiation of therapy). Results: Of 231 eligible patients, 196 consented to QOL, 102 on Arm A and 94 on Arm B. Compliance prior to start of RT and end of RT was 83%. At 1 and 2.5 yrs, 80% and 62% of pts, respectively, completed the EPIC. There were no differences between any EPIC domain between arms from the start of RT through the end of follow-up. Men on oreteronel had a significantly greater decline in bowel score prior to starting RT then control patients (-6.12, 95% confidence interval [CI]: -9.24, -3.01 vs. -1.93, 95% CI: -4.48, 0.63, respectively, p=0.038). Arm B patients also had a statistically significant and clinically meaningful worse change in urinary score vs control from baseline to pre-RT (-2.33, 95% CI: -5.02, 0.36 vs. 1.38, 95% CI: -1.07, 3.83, respectively, p=0.043). No other timepoints were significant. The only sig. between arm difference in EPIC sexual and hormonal scores was also at pre-RT in favor of Arm A over Arm B; p=0.024 and p=0.0024 respectively). Fatigue was also greater in the oreteronel patients prior to starting RT (3.81, 95% CI: 1.88, 5.74 vs. 1.18, 95% CI: -0.23, 2.60, p=0.028). Conclusion: The addition of oreteronel to RT and ADT resulted in greater declines in QOL prior to the start of RT but did not result in significant differences at any other time points. Although oreteronel development has been halted, the QOL results are encouraging for other drugs in this class that remain under investigation. In ongoing prospective trials, QOL impacts should be measured in conjunction with changes in clinical outcome and survival. This project was supported by grants UG1CA189867, U10CA180868, U10CA180822 from the National Cancer Institute and Takeda Pharmaceutical

Chapter 9 Outdoor air pollutants sources, characteristics, and impact on human health and the environment

In this chapter, sources and characteristics of outdoor air pollutants are presented along with their effects on human health and the environment. In addition, emphasis is given to air pollutant monitoring by exploring the type of monitoring programs, sampling methods, and emission standards and by presenting the case of air pollution monitoring in the United Arab Emirates. Finally, the chapter explores the case of climate change by looking into its causes and economic and environmental impacts

Analisis Tari TOR-TOR Dalam Upacara Adat Perkawinan Masyarakat Asal Mandailing Di Kota Duri Kabupaten Bengkalis Provinsi Riau

ANALYSIS OF THE TOR.TOR }ANCE IN THE TRADITIONAL MARRIAGE SERYICE OT THE COMMUNITY OF'MANI}AILING ORIGIN IN THtr CITY OF DURI BENGKALI DISTRICT RIAU PRO}TNCE DEMORA , L76714091 lVI.sn r024067801 ABSTRACT The purpose of this stud,v is to find out the anah,sis of the Tor-Tor Danse in the I'rad:itional Marriage Ceremony of the Mandailing Conrr"nunit-v in Duri City, Bengkalis Regency, Riau Province. This t1,pe of research is descriptive analysis method using non-interactive clr-ralitative data, narnely: the researcher is not involved and only as an independent observer. The data is obtained from primary data and secondary data, rvhich is derived from the original source and through data collection or data processing that is a documentation study. The results of the research for specific findings obtained by researchers based on the theory of Soedarsono (1998) namelv motion is the most irnportant lnedium in dance, music is the most important accompanirnent in a dance, floor design is the pattern that dancers cross, makeup is an important role in shaping facial etfects. dancers, tashion is a costume used on the dancer's body, lighting is a tool that can be used to illuminate a performance, stage setting is a support for dance performances that serves to create an afinosphere in the dance concept. in the analytical research conducted by researchers based on theory, researchers obtained the Tor-tor dance movements used in the traditional u,edding ceremony of the Mandailing community using sirnple movements with mov-ements using slor.v tempos, the music used using Gordang Sambilan, the floor design in this Tor-tor dance. triangurlar floor design consisting of three dancers and the dancers make changes in moticn, namely facing forward, right, left, back, then returning to the initial position, the make-up used by the bride is beautilul make-up, for the groorn only uses make-up. up natural, for the costumes worn by the bride and groom, namelv traditional Mandailing wedding clothes, on the lighting and stage in this traditional wedding ceremony, only bright neon lights and carpets are used as the stage setting. The general finding in this study is the analysis of the tor-tor dance in the traditional marriage ceremony of the rnandailing community in the city of thor