782 research outputs found
Fermion correlators in non-abelian holographic superconductors
We consider fermion correlators in non-abelian holographic superconductors.
The spectral function of the fermions exhibits several interesting features
such as support in displaced Dirac cones and an asymmetric distribution of
normal modes. These features are compared to similar ones observed in angle
resolved photoemission experiments on high T_c superconductors. Along the way
we elucidate some properties of p-wave superconductors in AdS_4 and discuss the
construction of SO(4) superconductors.Comment: 49 pages, 11 figure
The particle number in Galilean holography
Recently, gravity duals for certain Galilean-invariant conformal field
theories have been constructed. In this paper, we point out that the spectrum
of the particle number operator in the examples found so far is not a necessary
consequence of the existence of a gravity dual. We record some progress towards
more realistic spectra. In particular, we construct bulk systems with
asymptotic Schrodinger symmetry and only one extra dimension. In examples, we
find solutions which describe these Schrodinger-symmetric systems at finite
density. A lift to M-theory is used to resolve a curvature singularity. As a
happy byproduct of this analysis, we realize a state which could be called a
holographic Mott insulator.Comment: 29 pages, 1 rudimentary figure; v2: typo in eqn (3.4), added comments
and ref
Quantum magnetism and criticality
Magnetic insulators have proved to be fertile ground for studying new types
of quantum many body states, and I survey recent experimental and theoretical
examples. The insights and methods transfer also to novel superconducting and
metallic states. Of particular interest are critical quantum states, sometimes
found at quantum phase transitions, which have gapless excitations with no
particle- or wave-like interpretation, and control a significant portion of the
finite temperature phase diagram. Remarkably, their theory is connected to
holographic descriptions of Hawking radiation from black holes.Comment: 39 pages, 10 figures, review article for non-specialists; (v2) added
clarifications and references; (v3) minor corrections; (v4) added footnote on
hydrodynamic long-time tail
Efficient quantum state tomography
Quantum state tomography, the ability to deduce the state of a quantum system
from measured data, is the gold standard for verification and benchmarking of
quantum devices. It has been realized in systems with few components, but for
larger systems it becomes infeasible because the number of quantum measurements
and the amount of computation required to process them grows exponentially in
the system size. Here we show that we can do exponentially better than direct
state tomography for a wide range of quantum states, in particular those that
are well approximated by a matrix product state ansatz. We present two schemes
for tomography in 1-D quantum systems and touch on generalizations. One scheme
requires unitary operations on a constant number of subsystems, while the other
requires only local measurements together with more elaborate post-processing.
Both schemes rely only on a linear number of experimental operations and
classical postprocessing that is polynomial in the system size. A further
strength of the methods is that the accuracy of the reconstructed states can be
rigorously certified without any a priori assumptions.Comment: 9 pages, 4 figures. Combines many of the results in arXiv:1002.3780,
arXiv:1002.3839, and arXiv:1002.4632 into one unified expositio
Tubulin Tyrosination Is Required for the Proper Organization and Pathfinding of the Growth Cone
International audienceBACKGROUND: During development, neuronal growth cones integrate diffusible and contact guidance cues that are conveyed to both actin and microtubule (MT) cytoskeletons and ensure axon outgrowth and pathfinding. Although several post-translational modifications of tubulin have been identified and despite their strong conservation among species, their physiological roles during development, especially in the nervous sytem, are still poorly understood. METHODOLOGY/FINDINGS: Here, we have dissected the role of a post-translational modification of the last amino acid of the alpha-tubulin on axonal growth by analyzing the phenotype of precerebellar neurons in Tubulin tyrosin ligase knock-out mice (TTL(-/-)) through in vivo, ex vivo and in vitro analyses. TTL(-/-) neurons are devoid of tyrosinated tubulin. Their pathway shows defects in vivo, ex vivo, in hindbrains open-book preparations or in vitro, in a collagen matrix. Their axons still orient toward tropic cues, but they emit supernumerary branches and their growth cones are enlarged and exhibit an emission of mis-oriented filopodia. Further analysis of the TTL(-/-) growth cone intracellular organization also reveals that the respective localization of actin and MT filaments is disturbed, with a decrease in the distal accumulation of Myosin IIB, as well as a concomitant Rac1 over-activation in the hindbrain. Pharmacological inhibition of Rac1 over-activation in TTL(-/-) neurons can rescue Myosin IIB localization. CONCLUSIONS/SIGNIFICANCE: In the growth cone, we propose that tubulin tyrosination takes part in the relative arrangement of actin and MT cytoskeletons, in the regulation of small GTPases activity, and consequently, in the proper morphogenesis, organization and pathfinding of the growth cone during development
Developments in lattice quantum chromodynamics for matter at high temperature and density
A brief overview of the QCD phase diagram at nonzero temperature and density is provided. It is explained why standard lattice QCD techniques are not immediately applicable for its determination, due to the sign problem. We then discuss a selection of recent lattice approaches that attempt to evade the sign problem and classify them according to the underlying principle: constrained simulations (density of states, histograms), holomorphicity (complex Langevin, Lefschetz thimbles), partial summations (clusters, subsets, bags) and change in integration order (strong coupling, dual formulations)
Temperature Control of Fimbriation Circuit Switch in Uropathogenic Escherichia coli: Quantitative Analysis via Automated Model Abstraction
Uropathogenic Escherichia coli (UPEC) represent the predominant cause of urinary tract infections (UTIs). A key UPEC molecular virulence mechanism is type 1 fimbriae, whose expression is controlled by the orientation of an invertible chromosomal DNA elementâthe fim switch. Temperature has been shown to act as a major regulator of fim switching behavior and is overall an important indicator as well as functional feature of many urologic diseases, including UPEC host-pathogen interaction dynamics. Given this panoptic physiological role of temperature during UTI progression and notable empirical challenges to its direct in vivo studies, in silico modeling of corresponding biochemical and biophysical mechanisms essential to UPEC pathogenicity may significantly aid our understanding of the underlying disease processes. However, rigorous computational analysis of biological systems, such as fim switch temperature control circuit, has hereto presented a notoriously demanding problem due to both the substantial complexity of the gene regulatory networks involved as well as their often characteristically discrete and stochastic dynamics. To address these issues, we have developed an approach that enables automated multiscale abstraction of biological system descriptions based on reaction kinetics. Implemented as a computational tool, this method has allowed us to efficiently analyze the modular organization and behavior of the E. coli fimbriation switch circuit at different temperature settings, thus facilitating new insights into this mode of UPEC molecular virulence regulation. In particular, our results suggest that, with respect to its role in shutting down fimbriae expression, the primary function of FimB recombinase may be to effect a controlled down-regulation (rather than increase) of the ON-to-OFF fim switching rate via temperature-dependent suppression of competing dynamics mediated by recombinase FimE. Our computational analysis further implies that this down-regulation mechanism could be particularly significant inside the host environment, thus potentially contributing further understanding toward the development of novel therapeutic approaches to UPEC-caused UTIs
Observation of associated near-side and away-side long-range correlations in âsNN=5.02ââTeV proton-lead collisions with the ATLAS detector
Two-particle correlations in relative azimuthal angle (ÎÏ) and pseudorapidity (Îη) are measured in âsNN=5.02ââTeV p+Pb collisions using the ATLAS detector at the LHC. The measurements are performed using approximately 1ââÎŒb-1 of data as a function of transverse momentum (pT) and the transverse energy (ÎŁETPb) summed over 3.1<η<4.9 in the direction of the Pb beam. The correlation function, constructed from charged particles, exhibits a long-range (2<|Îη|<5) ânear-sideâ (ÎÏâŒ0) correlation that grows rapidly with increasing ÎŁETPb. A long-range âaway-sideâ (ÎÏâŒÏ) correlation, obtained by subtracting the expected contributions from recoiling dijets and other sources estimated using events with small ÎŁETPb, is found to match the near-side correlation in magnitude, shape (in Îη and ÎÏ) and ÎŁETPb dependence. The resultant ÎÏ correlation is approximately symmetric about Ï/2, and is consistent with a dominant cosâĄ2ÎÏ modulation for all ÎŁETPb ranges and particle pT
Search for R-parity-violating supersymmetry in events with four or more leptons in sqrt(s) =7 TeV pp collisions with the ATLAS detector
A search for new phenomena in final states with four or more leptons (electrons or muons) is presented. The analysis is based on 4.7 fbâ1 of proton-proton collisions delivered by the Large Hadron Collider and recorded with the ATLAS detector. Observations are consistent with Standard Model expectations in two signal regions: one that requires moderate values of missing transverse momentum and another that requires large effective mass. The results are interpreted in a simplified model of R-parity-violating supersymmetry in which a 95% CL exclusion region is set for charged wino masses up to 540 GeV. In an R-parity-violating MSUGRA/CMSSM model, values of m 1/2 up to 820 GeV are excluded for 10 < tan ÎČ < 40
Search for high-mass resonances decaying to dilepton final states in pp collisions at sâ=7 TeV with the ATLAS detector
The ATLAS detector at the Large Hadron Collider is used to search for high-mass resonances decaying to an electron-positron pair or a muon-antimuon pair. The search is sensitive to heavy neutral ZâČ gauge bosons, Randall-Sundrum gravitons, Z * bosons, techni-mesons, Kaluza-Klein Z/Îł bosons, and bosons predicted by Torsion models. Results are presented based on an analysis of pp collisions at a center-of-mass energy of 7 TeV corresponding to an integrated luminosity of 4.9 fbâ1 in the e + e â channel and 5.0 fbâ1 in the ÎŒ + ÎŒ âchannel. A Z âČ boson with Standard Model-like couplings is excluded at 95 % confidence level for masses below 2.22 TeV. A Randall-Sundrum graviton with coupling k/MPl=0.1 is excluded at 95 % confidence level for masses below 2.16 TeV. Limits on the other models are also presented, including Technicolor and Minimal ZâČ Models
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