1,417 research outputs found
The Profile of the Teaching Profession – Empirical Reflections on the Development of the Competences of University Teachers
AbstractIn this article we have proposed to present a theoretical and practical approach to the teaching profession, based on analysis competencies, which should hold them a good university teacher in a globalized and competitive world. The results of the study were obtained by applying a written questionnaire to subjects who work in different universities from Romania and Spain. The study included a total of 485 people from four universities in Spain and four universities in Romania. The results obtained by analyzing the responses of the subjects included in our sample have showed that both groups of teachers – from Romania an Spain – have the same opinions regarding the competencies which should hold them a good university teacher but were registered significant mean differences regarding transversal competencies dimension (p=0,002, p< 0,05). We believe that the professional perfection and development are the sources of a professional continuum, which makes educational career rolling laws and is subject to management resources, mobility needs, and flexibility of the teaching staff
A kinematic study of the irregular dwarf galaxy NGC 2366 using HI and Halpha observations
Abridged. Context. The metal content of dwarf galaxies and the metal
enrichment of the intergalactic medium both suggest that mass loss from
galaxies is a significant factor for the chemical evolution history of
galaxies, in particular of dwarf galaxies. However, no clear evidence of a
blow-away in local dwarf galaxies has been found so far.
Aims. We therefore performed a detailed kinematic analysis of the neutral and
ionised gas in the nearby star-forming irregular dwarf galaxy NGC 2366 in order
to make predictions about the fate of the gas and to get a more complete
picture of this galaxy.
Methods. A deep Halpha image and Fabry-Perot interferometric data of NGC 2366
were obtained. They were complemented by HI synthesis data from the THINGS
survey. We searched for line-splitting both in Halpha and HI by performing a
Gaussian decomposition. To get an idea whether the expansion velocities are
high enough for a gas blow-away, we used the pseudo-isothermal halo model,
which gives us realistic values for the escape velocities of NGC 2366. The good
data quality also allowed us to discuss some peculiarities of the morphology
and the dynamics in NGC 2366.
Results. A large red-shifted outflow north west of the giant extragalactic
HII region with an expansion velocity of up to 50 km/s is found in Halpha, but
not in HI. Additionally, a blue-shifted component north of the giant
extragalactic HII region was detected both in Halpha and HI with an expansion
velocity of up to 30 km/s. A comparison with the escape velocities of NGC 2366
reveals that the gas does not have enough kinetic energy to leave the
gravitational potential.Comment: 15 pages, 14 figures, accepted for publication by A&
Spiral inflow feeding the nuclear starburst in M83, observed in H-alpha emission with the GHAFAS Fabry-Perot interferometer
We present observations of the nearby barred starburst galaxy, M83 (NGC5236),
with the new Fabry-Perot interferometer GHAFAS mounted on the 4.2 meter William
Herschel Telescope on La Palma. The unprecedented high resolution observations,
of 16 pc/FWHM, of the H-alpha-emitting gas cover the central two kpc of the
galaxy. The velocity field displays the dominant disk rotation with signatures
of gas inflow from kpc scales down to the nuclear regions. At the inner Inner
Lindblad Resonance radius of the main bar and centerd at the dynamical center
of the main galaxy disk, a nuclear rapidly
rotating disk with scale length of pc has formed. The nuclear
starburst is found in the vicinity as well as inside this nuclear disk, and our
observations confirm that gas spirals in from the outer parts to feed the
nuclear starburst, giving rise to several star formation events at different
epochs, within the central 100 pc radius of M83.Comment: Accepted for publication in ApJ Letters. High-resolution version can
be found at http://www.astro.su.se/~kambiz/DOC/paper-M83.pd
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Impact of Th1 CD4 Follicular Helper T Cell Skewing on Antibody Responses to an HIV-1 Vaccine in Rhesus Macaques.
Generating durable humoral immunity through vaccination depends upon effective interactions of follicular helper T (Tfh) cells with germinal center (GC) B cells. Th1 polarization of Tfh cells is an important process shaping the success of Tfh-GC B cell interactions by influencing costimulatory and cytokine-dependent Tfh help to B cells. However, the question remains as to whether adjuvant-dependent modulation of Tfh cells enhances HIV-1 vaccine-induced antienvelope (anti-Env) antibody responses. We investigated whether an HIV-1 vaccine platform designed to increase the number of Th1-polarized Tfh cells enhances the magnitude and quality of anti-Env antibodies. Utilizing a novel interferon-induced protein 10 (IP-10)-adjuvanted HIV-1 DNA prime followed by a monophosphoryl lipid A and QS-21 (MPLA+QS-21)-adjuvanted Env protein boost (DIP-10 PALFQ) in macaques, we observed higher anti-Env serum IgG titers with greater cross-clade reactivity, specificity for V1V2, and effector functions than in macaques primed with DNA lacking IP-10 and boosted with MPLA-plus-alum-adjuvanted Env protein (DPALFA) The DIP-10 PALFQ vaccine regimen elicited higher anti-Env IgG1 and lower IgG4 antibody levels in serum, showing for the first time that adjuvants can dramatically impact the IgG subclass profile in macaques. The DIP-10 PALFQ regimen also increased vaginal and rectal IgA antibodies to a greater extent. Within lymph nodes, we observed augmented GC B cell responses and the promotion of Th1 gene expression profiles in GC Tfh cells. The frequency of GC Tfh cells correlated with both the magnitude and avidity of anti-Env serum IgG. Together, these data suggest that adjuvant-induced stimulation of Th1-Tfh cells is an effective strategy for enhancing the magnitude and quality of anti-Env antibody responses.IMPORTANCE The results of the RV144 trial demonstrated that vaccination could prevent HIV transmission in humans and that longevity of anti-Env antibodies may be key to this protection. Efforts to improve upon the prime-boost vaccine regimen used in RV144 have indicated that booster immunizations can increase serum anti-Env antibody titers but only transiently. Poor antibody durability hampers efforts to develop an effective HIV-1 vaccine. This study was designed to identify the specific elements involved in the immunological mechanism necessary to produce robust HIV-1-specific antibodies in rhesus macaques. By clearly defining immune-mediated pathways that improve the magnitude and functionality of the anti-HIV-1 antibody response, we will have the foundation necessary for the rational development of an HIV-1 vaccine
Longitudinal relationships between caloric expenditure and gray matter in the cardiovascular health study
Background: Physical activity (PA) can be neuroprotective and reduce the risk for Alzheimer’s disease (AD). In assessing physical activity, caloric expenditure is a proxy marker reflecting the sum total of multiple physical activity types conducted by an individual. Objective:To assess caloric expenditure, as a proxy marker of PA, as a predictive measure of gray matter (GM) volumes in the normal and cognitively impaired elderly persons. Methods: All subjects in this study were recruited from the Institutional Review Board approved Cardiovascular Health Study (CHS), a multisite population-based longitudinal study in persons aged 65 and older. We analyzed a sub-sample of CHS participants 876 subjects (mean age 78.3, 57.5% F, 42.5% M) who had i) energy output assessed as kilocalories (kcal) per week using the standardized Minnesota Leisure-Time Activities questionnaire, ii) cognitive assessments for clinical classification of normal cognition, mild cognitive impairment (MCI), and AD, and iii) volumetric MR imaging of the brain. Voxel-based morphometry modeled the relationship between kcal/week and GM volumes while accounting for standard covariates including head size, age, sex, white matter hyperintensity lesions, MCI or AD status, and site. Multiple comparisons were controlled using a False Discovery Rate of 5 percent. Results: Higher energy output, from a variety of physical activity types, was associated with larger GM volumes in frontal, temporal, and parietal lobes, as well as hippocampus, thalamus, and basal ganglia. High levels of caloric expenditure moderated neurodegeneration-associated volume loss in the precuneus, posterior cingulate, and cerebellar vermis. Conclusion:Increasing energy output from a variety of physical activities is related to larger gray matter volumes in the elderly, regardless of cognitive status.Cyrus A. Raji, David A. Merrill, Harris Eyre, Sravya Mallam, Nare Torosyan, Kirk I. Erickson, Oscar L. Lopez , James T. Becker, Owen T. Carmichael, H. Michael Gach, Paul M. Thompson, W.T. Longstreth, Jr. and Lewis H. Kulle
A new measurement of the properties of the rare decay K -> pi+ e+ e-
A large low-background sample of events (10300) has been collected for the
rare decay of kaons in flight K+ -> pi+ e+ e- by experiment E865 at the
Brookhaven AGS. The decay products were accepted by a broad band
high-resolution charged particle spectrometer with particle identification. The
branching ratio (2.94 +- 0.05(stat.) +- 0.13(syst.) +- 0.05(model))*10**{-7}
was determined normalizing to events from the decay chain K+ -> pi+ pi0; pi0 ->
e+ e- gamma. From the analysis of the decay distributions the vector nature of
this decay is firmly established now, and limits on scalar and tensor
contributions are deduced. From the (e+ e-) invariant mass distribution the
decay form factor f(z)=f0(1+ delta*z) (z=M(ee)**2/m(K)**2) is determined with
delta=2.14 +- 0.13 +- 0.15. Chiral QCD perturbation theory predictions for the
form factor are also tested, and terms beyond leading order O(p**4) are found
to be important.Comment: 4 pages, 5 figure
Combined QCD and electroweak analysis of HERA data
A simultaneous fit of parton distribution functions (PDFs) and electroweak
parameters to HERA data on deep inelastic scattering is presented. The input
data are the neutral current and charged current inclusive cross sections which
were previously used in the QCD analysis leading to the HERAPDF2.0 PDFs. In
addition, the polarisation of the electron beam was taken into account for the
ZEUS data recorded between 2004 and 2007. Results on the vector and
axial-vector couplings of the Z boson to u- and d-type quarks, on the value of
the electroweak mixing angle and the mass of the W boson are presented. The
values obtained for the electroweak parameters are in agreement with Standard
Model predictions.Comment: 32 pages, 10 figures, accepted by Phys. Rev. D. Small corrections
from proofing process and small change to Fig. 12 and Table
Measurement of the cross-section and charge asymmetry of bosons produced in proton-proton collisions at TeV with the ATLAS detector
This paper presents measurements of the and cross-sections and the associated charge asymmetry as a
function of the absolute pseudorapidity of the decay muon. The data were
collected in proton--proton collisions at a centre-of-mass energy of 8 TeV with
the ATLAS experiment at the LHC and correspond to a total integrated luminosity
of 20.2~\mbox{fb^{-1}}. The precision of the cross-section measurements
varies between 0.8% to 1.5% as a function of the pseudorapidity, excluding the
1.9% uncertainty on the integrated luminosity. The charge asymmetry is measured
with an uncertainty between 0.002 and 0.003. The results are compared with
predictions based on next-to-next-to-leading-order calculations with various
parton distribution functions and have the sensitivity to discriminate between
them.Comment: 38 pages in total, author list starting page 22, 5 figures, 4 tables,
submitted to EPJC. All figures including auxiliary figures are available at
https://atlas.web.cern.ch/Atlas/GROUPS/PHYSICS/PAPERS/STDM-2017-13
Search for chargino-neutralino production with mass splittings near the electroweak scale in three-lepton final states in √s=13 TeV pp collisions with the ATLAS detector
A search for supersymmetry through the pair production of electroweakinos with mass splittings near the electroweak scale and decaying via on-shell W and Z bosons is presented for a three-lepton final state. The analyzed proton-proton collision data taken at a center-of-mass energy of √s=13 TeV were collected between 2015 and 2018 by the ATLAS experiment at the Large Hadron Collider, corresponding to an integrated luminosity of 139 fb−1. A search, emulating the recursive jigsaw reconstruction technique with easily reproducible laboratory-frame variables, is performed. The two excesses observed in the 2015–2016 data recursive jigsaw analysis in the low-mass three-lepton phase space are reproduced. Results with the full data set are in agreement with the Standard Model expectations. They are interpreted to set exclusion limits at the 95% confidence level on simplified models of chargino-neutralino pair production for masses up to 345 GeV
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