798 research outputs found

    Excited state quantum phase transitions in many-body systems

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    Phenomena analogous to ground state quantum phase transitions have recently been noted to occur among states throughout the excitation spectra of certain many-body models. These excited state phase transitions are manifested as simultaneous singularities in the eigenvalue spectrum (including the gap or level density), order parameters, and wave function properties. In this article, the characteristics of excited state quantum phase transitions are investigated. The finite-size scaling behavior is determined at the mean field level. It is found that excited state quantum phase transitions are universal to two-level bosonic and fermionic models with pairing interactions.Comment: LaTeX (elsart), 37 pages; to be published in Ann. Phys. (N.Y.

    Single-shot nanosecond-resolution multiframe passive imaging by multiplexed structured image capture

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    The Multiplexed Structured Image Capture (MUSIC) technique is used to demonstrate single-shot multiframe passive imaging, with a nanosecond difference between the resulting images. This technique uses modulation of light from a scene before imaging, in order to encode the target’s temporal evolution into spatial frequency shifts, each of which corresponds to a unique time and results in individual and distinct snapshots. The resulting images correspond to different effective imaging gate times, because of the optical path delays. Computer processing of the multiplexed single-shot image recovers the nanosecond-resolution evolution. The MUSIC technique is used to demonstrate imaging of a laser-induced plasma. Simultaneous single-shot measurements of electron numbers by coherent microwave scattering were obtained and showed good agreement with MUSIC characterization. The MUSIC technique demonstrates spatial modulation of images used for passive imaging. This allows multiple frames to be stacked into a single image. This method could also pave the way for real-time imaging and characterization of ultrafast processes and visualization, as well as general tracking of fast objects

    Intravitreal Administration of Human Bone Marrow CD34+ Stem Cells in a Murine Model of Retinal Degeneration.

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    PurposeIntravitreal murine lineage-negative bone marrow (BM) hematopoietic cells slow down retinal degeneration. Because human BM CD34+ hematopoietic cells are not precisely comparable to murine cells, this study examined the effect of intravitreal human BM CD34+ cells on the degenerating retina using a murine model.MethodsC3H/HeJrd1/rd1 mice, immunosuppressed systemically with tacrolimus and rapamycin, were injected intravitreally with PBS (n = 16) or CD34+ cells (n = 16) isolated from human BM using a magnetic cell sorter and labeled with enhanced green fluorescent protein (EGFP). After 1 and 4 weeks, the injected eyes were imaged with scanning laser ophthalmoscopy (SLO)/optical coherence tomography (OCT) and tested with electroretinography (ERG). Eyes were harvested after euthanasia for immunohistochemical and microarray analysis of the retina.ResultsIn vivo SLO fundus imaging visualized EGFP-labeled cells within the eyes following intravitreal injection. Simultaneous OCT analysis localized the EGFP-labeled cells on the retinal surface resulting in a saw-toothed appearance. Immunohistochemical analysis of the retina identified EGFP-labeled cells on the retinal surface and adjacent to ganglion cells. Electroretinography testing showed a flat signal both at 1 and 4 weeks following injection in all eyes. Microarray analysis of the retina following cell injection showed altered expression of more than 300 mouse genes, predominantly those regulating photoreceptor function and maintenance and apoptosis.ConclusionsIntravitreal human BM CD34+ cells rapidly home to the degenerating retinal surface. Although a functional benefit of this cell therapy was not seen on ERG in this rapidly progressive retinal degeneration model, molecular changes in the retina associated with CD34+ cell therapy suggest potential trophic regenerative effects that warrant further exploration

    Controlling chaos in area-preserving maps

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    We describe a method of control of chaos that occurs in area-preserving maps. This method is based on small modifications of the original map by addition of a small control term. We apply this control technique to the standard map and to the tokamap

    Genetics of Dothistromin Biosynthesis of Dothistroma septosporum: An Update

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    Dothistroma needle blight is one of the most devastating fungal pine diseases worldwide. The disease is characterized by accumulation in pine needles of a red toxin, dothistromin, that is chemically related to aflatoxin (AF) and sterigmatocystin (ST). This review updates current knowledge of the genetics of dothistromin biosynthesis by the Dothistroma septosporum pathogen and highlights differences in gene organization and regulation that have been discovered between the dothistromin and AF/ST systems. Some previously reported genes are promoted or demoted as ‘dothistromin genes’ based on recent research. A new dothistromin gene, norB, is reported, and evidence of dothistromin gene homologs in other Dothideomycete fungi is presented. A hypothesis for the biological role of dothistromin is outlined. Finally, the impact that the availability of the D. septosporum genome sequence will have on dothistromin research is discussed

    Structures, properties, and applications of CNT-graphene heterostructures

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    Both carbon nanotube (CNT) and graphene exhibit excellent properties and have many potential applications in integrated circuits, composite materials, thermal management, sensors, energy storage, and flexible electronics. However, their superior properties are confined to one or two dimensions, thus limiting their utility in interconnects or thermal interface materials that require a 3D structure for efficient electron and/or phonon transport. It is conceivable that a combined CNT-graphene structure would provide new opportunities for realizable applications in these and other fields. In recent years, numerous results on synthesis, structural analyses, theoretical modeling, and potential applications of various CNT-graphene heterostructures have been reported. In this review, we summarize the possible structures that can be formed by connecting CNT and graphene. We then report existing experimental efforts to synthesize the heterostructures based on growth method, catalyst design, and the resulting properties. Also, theoretical studies on various heterostructures are reviewed, with the focus on electron and thermal transport within the heterostructure and across the CNT-graphene interface. Several potential applications are briefly discussed, and a combined theoretical and experimental approach is proposed with the objective of enhancing the understanding of the CNT-graphene heterostructure and attaining a realistic assessment of its feasibility in practical applications

    Evaluation of the Algorithms and Parameterizations for Ground Thawing and Freezing Simulation in Permafrost Regions

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    Ground thawing and freezing depths (GTFDs) strongly influence the hydrology and energy balances of permafrost regions. Current methods to simulate GTFD differ in algorithm type, soil parameterization, representation of latent heat, and unfrozen water content. In this study, five algorithms (one semiempirical, two analytical, and two numerical), three soil thermal conductivity parameterizations, and three unfrozen water parameterizations were evaluated against detailed field measurements at four field sites in Canada’s discontinuous permafrost region. Key findings include: (1) de Vries’ parameterization is recommended to determine the thermal conductivity in permafrost soils; (2) the three unfrozen water parameterization methods exhibited little difference in terms of GTFD simulations, yet the segmented linear function is the simplest to be implemented; (3) the semiempirical algorithm reasonably simulates thawing at permafrost sites and freezing at seasonal frost sites with site-specific calibration. However, large interannual and intersite variations in calibration coefficients limit its applicability for dynamic analysis; (4) when driven by surface forcing, analytical algorithms performed marginally better than the semiempirical algorithm. The inclusion of bottom forcing improved analytical algorithm performance, yet their results were still poor compared with those achieved by numerical algorithms; (5) when supplied with the optimal inputs, soil parameterizations, and model configurations, the numerical algorithm with latent heat treated as an apparent heat capacity achieved the best GTFD simulations among all algorithms at all sites. Replacing the observed bottom temperature with a zero heat flux boundary condition did not significantly reduce simulation accuracy, while assuming a saturated profile caused large errors at several sites

    Genetics of Dothistromin Biosynthesis in the Peanut Pathogen Passalora arachidicola

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    The peanut leaf spot pathogen Passalora arachidicola (Mycosphaerella arachidis) is known to produce dothistromin, a mycotoxin related to aflatoxin. This is a feature shared with the pine needle pathogen Dothistroma septosporum (Mycosphaerella pini). Dothistromin biosynthesis in D. septosporum commences at an unusually early stage of growth in culture compared to most other fungal secondary metabolites, and the biosynthetic genes are arranged in fragmented groups, in contrast to aflatoxin gene clusters. Dothistromin biosynthetic genes were identified and studied in P. arachidicola to determine if the attributes described in D. septosporum are shared by another dothistromin-producing species within the Class Dothideomycetes. It was shown that dothistromin biosynthesis is very similar in the two species with regard to gene sequence and gene synteny. Functional complementation of D. septosporum mutants with P. arachidicola dothistromin genes was also possible. These similarities support a vertical mode of dothistromin gene transmission. P. arachidicola also produced dothistromin at an early growth stage in culture, suggesting that this type of regulation pattern may be relevant to the biological role of dothistromin

    Quantum phase transitions in the interacting boson model

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    This review is focused on various properties of quantum phase transitions (QPTs) in the Interacting Boson Model (IBM) of nuclear structure. The model in its infinite-size limit exhibits shape-phase transitions between spherical, deformed prolate, and deformed oblate forms of the ground state. Finite-size precursors of such behavior are verified by robust variations of nuclear properties (nuclear masses, excitation energies, transition probabilities for low lying levels) across the chart of nuclides. Simultaneously, the model serves as a theoretical laboratory for studying diverse general features of QPTs in interacting many-body systems, which differ in many respects from lattice models of solid-state physics. We outline the most important fields of the present interest: (a) The coexistence of first- and second-order phase transitions supports studies related to the microscopic origin of the QPT phenomena. (b) The competing quantum phases are characterized by specific dynamical symmetries and novel symmetry related approaches are developed to describe also the transitional dynamical domains. (c) In some parameter regions, the QPT-like behavior can be ascribed also to individual excited states, which is linked to the thermodynamic and classical descriptions of the system. (d) The model and its phase structure can be extended in many directions: by separating proton and neutron excitations, considering odd-fermion degrees of freedom or different particle-hole configurations, by including other types of bosons, higher order interactions, and by imposing external rotation. All these aspects of IBM phase transitions are relevant in the interpretation of experimental data and important for a fundamental understanding of the QPT phenomenon.Comment: a review article, 71 pages, 18 figure
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