Heavy Metal Contamination of Soil and Surface Water in the Arufu Lead-Zinc Mining District, Middle Benue Trough, Nigeria

This paper is aimed at investigating the nature of heavy metals dispersion in soil and surface water around the Arufu leadzinc mine, Middle Benue Trough, Nigeria. Rock samples from mine pits and adjoining outcrops as well as water samples from mine pits and adjacent streams were collected and analyzed. Also analysed were soil samples collected from mine waste and adjoining areas as well as from a forest to serve as control. All samples were analysed for Fe, Zn, Mn, Cu, Pb, Cr, As, Cd and Ag, using atomic absorption spectrophotometer (AAS). Organic Matter (OM) content of the soil samples, and the pH of both soil and water samples were also determined. The results show that the OM content of soil was generally low (4 + 1.1%) and both soil and water samples were characterized by moderate pH values of 6.30 to 8.00 and 5.60 to 7.80 respectively. Furthermore, soils developed over bedrock show normal (background) levels of heavy metals, while soils developed over mine waste are enriched in Zn (181 + 83 mg/kg); Pb (40 + 28 mg/kg) and Cd (3 + 2 mg/kg). Also, water samples from mine ponds are enriched in Pb (0.02 – 0.10 mg/1) and Cd (0.02 – 0.04 mg/1). The sources of these heavy metals are most probably sulphides in the mine waste. Tailing and mine pits may therefore represent point sources of heavy metal contaminants and should therefore be reclaimed to prevent further contamination

Influence of mine drainage on water quality along River Nyaba in Enugu South-Eastern Nigeria

Major and Trace elements concentration were measured in water samples collected in and around Okpara coal mine in Enugu southeastern Nigeria to investigate the influence of mine drainage on the quality of water. The cations and trace elements were determined by ICP- MS while the anions were measured by spectrophotometer and titration methods. Field parameters such as pH, temperature and conductivity were determined in the field using standard equipment. The results show that the water is acidic to moderately acidic (pH 2.84 to 6.69) with pH increasing along the flow direction. The mean values of pH (4.66 (dry), 4.22 (wet), Color (334.34 TCU (dry), 153.11 TCU (wet) and turbidity (53,67 NTU (dry), 17.43 NTU (wet) as well as iron (6.35 mg/L(dry), 5.14 mg/L(wet), aluminum(1.14 mg/L(dry), 4.30 mg/L(wet), manganese (1.43 mg/L(dry), 5.36 mg/L (wet) and nickel, 0.053 mg/L (wet) recorded in the dry and wet seasons are above levels recommended by WHO for drinking water and other domestic purposes. Mean levels of fluoride (5.4 mg/L) with ranged of 0.00 to 45 mg/L, potassium (12 mg/L) with ranged of 1.17 to 27.85 mg/L and nickel (53.10 ìg/L) with ranged of 1.50 to 309.30 ìg/L, as well as maximum levels of chromium (100 ìg/L) with ranged of 0.05 to 100 ìg/L , chloride(400 mg/L) with ranged of 40 to 400 mg/L, nitrate(1012 mg/L) with ranged of 158 to 1012 mg/L and sulphate (517 mg/L) with ranged of 10 to 512 mg/L obtained in the wet season are above the WHO maximum permissible level. Generally, the levels of the elements decrease with distance away from the mine waste except for nitrate and fluoride. Thus the quality of the water is most probably influenced by acidic mine drainage and it impact on human health and the environment could be severe. Microbial assessment and element speciation are recommended for further quality assessment in the study area

Prevalence of obesity and ethno-geographic variation in body sizes of Nigerians with type 2 diabetes mellitus - a multi-centre study

BACKGROUND: Excess weight gain is common in people with type 2 diabetes mellitus (DM) but little is known about its ethno-geographic variation among the Nigerian populace. We aimed to report the prevalence and regional variation of overweight/obesity among subjects with type 2 DM in all the six geo-political regions of Nigeria.METHOD: Basic demographic and anthropometric data were consecutively collected from patients with type 2 DM attending out-patient clinics of seven designated teaching hospitals in the six geographic regions of the country using a pre-agreed method of measurement of anthropometry including waist circumference. The study was hospital-based descriptive cross-sectional in design. Body Mass Index (BMI) was categorised using the WHO criteria. Based on recommendations of the International Diabetes Federation (IDF) cut-off values for waist circumference, values >94 cm and > 80 cm were taken as abnormal for men and women respectively.RESULTS: A total of 709 subjects with DM comprising 378 (53.3%) females and 331 (46.7%) males (female: male ratio 1:1.14) with an overall mean age (SD) of 51.9 (13.9) years were evaluated. The prevalence of excess body weight among Nigerian subjects with type 2 DM was: peripheral (417 or 58.8%) and abdominal obesity (449 or 63.3%). Also, there was a significant wide variation in excess weight gain (both peripheral and central) across ethno-geographic regions (p=0.001) and between both sexes (p=0.001). In both peripheral and abdominal obesities, whether intra or inter centres, the female subjects with type 2 DM demonstrated relatively higher proportions of anthropometric measures. Generally, subjects from south-south and south-east Nigeria had higher BMI and abdominal obesity compared to those from south-west who had the lowest. The female subjects with type 2 DM were heavier peripherally and centrally compared to their male counterparts.CONCLUSION: The prevalence of peripheral and central obesity among Nigerians living with type 2 DM (especially the female subjects) is unacceptably high. Additionally, there is a wide variation in the proportion and absolute values of both peripheral and central obesity across different parts of Nigeria.KEY WORDS: Obesity, Prevalence, Ethno-Geographic Variation, Nigerians, Type 2 Diabetes Mellitu

Earliest evidence of pollution by heavy metals in archaeological sites

Homo species were exposed to a new biogeochemical environment when they began to occupy caves. Here we report the first evidence of palaeopollution through geochemical analyses of heavy metals in four renowned archaeological caves of the Iberian Peninsula spanning the last million years of human evolution. Heavy metal contents reached high values due to natural (guano deposition) and anthropogenic factors (e.g. combustion) in restricted cave environments. The earliest anthropogenic pollution evidence is related to Neanderthal hearths from Gorham's Cave (Gibraltar), being one of the first milestones in the so-called “Anthropocene”. According to its heavy metal concentration, these sediments meet the present-day standards of “contaminated soil”. Together with the former, the Gibraltar Vanguard Cave, shows Zn and Cu pollution ubiquitous across highly anthropic levels pointing to these elements as potential proxies for human activities. Pb concentrations in Magdalenian and Bronze age levels at El Pirulejo site can be similarly interpreted. Despite these high pollution levels, the contaminated soils might not have posed a major threat to Homo populations. Altogether, the data presented here indicate a long-term exposure of Homo to these elements, via fires, fumes and their ashes, which could have played certain role in environmental-pollution tolerance, a hitherto neglected influence.Francisco J. Jiménez Palacios and to the Analytical Chemistry Department (Sevilla University) are gratefully acknowledged for their help in the use of Carbolite electric oven. A.G.-A. was supported by a Marie Curie Intra-European Fellowship of the 7th Framework Programme for Research, Technological Development and Demonstration (European Commission). R.B. is a Beatriu de Pinós-A post-doctoral fellowship recipient (Generalitat de Catalunya and COFUND Marie Curie Actions, EU-FP7). This work also was partially financed by projects 19434/PI/14 Fundación Séneca, HARP2013-44269P, CGL-BOS-2012-34717, CGL2012-38434-C03-03 and CGL2012-38358 Ministerio de Economía y Competitividad, 2014 SGR 900 and 2014/100573 Generalitat de Catalunya-AGAUR, RNM 432 Research Group 179 (Junta de Andalucia) and MEXT-Japan

Measuring routine childhood vaccination coverage in 204 countries and territories, 1980-2019: a systematic analysis for the Global Burden of Disease Study 2020, Release 1

Background: Measuring routine childhood vaccination is crucial to inform global vaccine policies and programme implementation, and to track progress towards targets set by the Global Vaccine Action Plan (GVAP) and Immunization Agenda 2030. Robust estimates of routine vaccine coverage are needed to identify past successes and persistent vulnerabilities. Drawing from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2020, Release 1, we did a systematic analysis of global, regional, and national vaccine coverage trends using a statistical framework, by vaccine and over time. // Methods: For this analysis we collated 55 326 country-specific, cohort-specific, year-specific, vaccine-specific, and dose-specific observations of routine childhood vaccination coverage between 1980 and 2019. Using spatiotemporal Gaussian process regression, we produced location-specific and year-specific estimates of 11 routine childhood vaccine coverage indicators for 204 countries and territories from 1980 to 2019, adjusting for biases in country-reported data and reflecting reported stockouts and supply disruptions. We analysed global and regional trends in coverage and numbers of zero-dose children (defined as those who never received a diphtheria-tetanus-pertussis [DTP] vaccine dose), progress towards GVAP targets, and the relationship between vaccine coverage and sociodemographic development. // Findings: By 2019, global coverage of third-dose DTP (DTP3; 81·6% [95% uncertainty interval 80·4–82·7]) more than doubled from levels estimated in 1980 (39·9% [37·5–42·1]), as did global coverage of the first-dose measles-containing vaccine (MCV1; from 38·5% [35·4–41·3] in 1980 to 83·6% [82·3–84·8] in 2019). Third-dose polio vaccine (Pol3) coverage also increased, from 42·6% (41·4–44·1) in 1980 to 79·8% (78·4–81·1) in 2019, and global coverage of newer vaccines increased rapidly between 2000 and 2019. The global number of zero-dose children fell by nearly 75% between 1980 and 2019, from 56·8 million (52·6–60·9) to 14·5 million (13·4–15·9). However, over the past decade, global vaccine coverage broadly plateaued; 94 countries and territories recorded decreasing DTP3 coverage since 2010. Only 11 countries and territories were estimated to have reached the national GVAP target of at least 90% coverage for all assessed vaccines in 2019. // Interpretation: After achieving large gains in childhood vaccine coverage worldwide, in much of the world this progress was stalled or reversed from 2010 to 2019. These findings underscore the importance of revisiting routine immunisation strategies and programmatic approaches, recentring service delivery around equity and underserved populations. Strengthening vaccine data and monitoring systems is crucial to these pursuits, now and through to 2030, to ensure that all children have access to, and can benefit from, lifesaving vaccines

Five insights from the Global Burden of Disease Study 2019

The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019 provides a rules-based synthesis of the available evidence on levels and trends in health outcomes, a diverse set of risk factors, and health system responses. GBD 2019 covered 204 countries and territories, as well as first administrative level disaggregations for 22 countries, from 1990 to 2019. Because GBD is highly standardised and comprehensive, spanning both fatal and non-fatal outcomes, and uses a mutually exclusive and collectively exhaustive list of hierarchical disease and injury causes, the study provides a powerful basis for detailed and broad insights on global health trends and emerging challenges. GBD 2019 incorporates data from 281 586 sources and provides more than 3.5 billion estimates of health outcome and health system measures of interest for global, national, and subnational policy dialogue. All GBD estimates are publicly available and adhere to the Guidelines on Accurate and Transparent Health Estimate Reporting. From this vast amount of information, five key insights that are important for health, social, and economic development strategies have been distilled. These insights are subject to the many limitations outlined in each of the component GBD capstone papers.Peer reviewe

Pooled analysis of WHO Surgical Safety Checklist use and mortality after emergency laparotomy

Background The World Health Organization (WHO) Surgical Safety Checklist has fostered safe practice for 10 years, yet its place in emergency surgery has not been assessed on a global scale. The aim of this study was to evaluate reported checklist use in emergency settings and examine the relationship with perioperative mortality in patients who had emergency laparotomy. Methods In two multinational cohort studies, adults undergoing emergency laparotomy were compared with those having elective gastrointestinal surgery. Relationships between reported checklist use and mortality were determined using multivariable logistic regression and bootstrapped simulation. Results Of 12 296 patients included from 76 countries, 4843 underwent emergency laparotomy. After adjusting for patient and disease factors, checklist use before emergency laparotomy was more common in countries with a high Human Development Index (HDI) (2455 of 2741, 89.6 per cent) compared with that in countries with a middle (753 of 1242, 60.6 per cent; odds ratio (OR) 0.17, 95 per cent c.i. 0.14 to 0.21, P <0001) or low (363 of 860, 422 per cent; OR 008, 007 to 010, P <0.001) HDI. Checklist use was less common in elective surgery than for emergency laparotomy in high-HDI countries (risk difference -94 (95 per cent c.i. -11.9 to -6.9) per cent; P <0001), but the relationship was reversed in low-HDI countries (+121 (+7.0 to +173) per cent; P <0001). In multivariable models, checklist use was associated with a lower 30-day perioperative mortality (OR 0.60, 0.50 to 073; P <0.001). The greatest absolute benefit was seen for emergency surgery in low- and middle-HDI countries. Conclusion Checklist use in emergency laparotomy was associated with a significantly lower perioperative mortality rate. Checklist use in low-HDI countries was half that in high-HDI countries.Peer reviewe

Assessment of heavy metals pollution in sediments and surface water of River Benue, Makurdi, Nigeria

Levels of heavy metals were determined in the surface (1-6cm) and body core (45-50cm) sediments, as well as the overlying water of River Benue within the industrialized areas of Makurdi, Nigeria in order to assess the extent of anthropogenic influences. Samples were analyzed for their concentrations of these metals, using the atomic absorption spectrophotometer (AAS). The results of heavy metals show that the average contents of Fe (5.3%), Cr (70 ppm), Cd (0.4ppm) and Co (40ppm) in surface sediments are only slightly higher than corresponding contents in body core sediments; Fe (5.1%), Cr (66ppm), Cd (0.35ppm) and Co (37ppm). These chronic levels suggest similar geochemical control, which is most probably lithogenic. Conversely, the average contents of Mn (1910ppm), Cu (71ppm), Pb (26ppm) and Zn (340ppm) in surface sediments are much higher than corresponding contents in body core sediments; Mn (400ppm), Cu (30ppm), Pb (17ppm) and Zn (96ppm) respectively. These heavy metals are probably enhanced in surface sediments by anthropogenic activities. Results obtained from water analyses, are within the WHO 1991 maximum permissible level for most heavy metals in drinking water except for Mn (0.06-2.00ppm) and Pb (0.02-0.10ppm) close to point sources of pollution.Keywords: Heavy metals; Surface water; Sediments; River BenueJournal of Applied Science, Engineering and Technology Volume9,: 1-1

Prevalence of Demodicosis of Dogs in Makurdi Metropolis

A survey of prevalence of demodicosis of dogs was conducted between  October, 2010 and April, 2011 in Makurdi Metropolis. A total of 316 dogs were sampled. 111(35.1%) of the dogs were positive of the disease. The Local breed (Nigeria Mongrels) were the most affected 65(58.6%) followed by Cross breeds (Nigeria Mongrel and exotic breeds) 33(29.7%) and exotic breeds 13(11.7%) were the least affected. The age group most affected was between1and 4years 61(55%). There was no significant difference in sex distribution. The clinical signs observed in dogs with the disease were pruritus, alopecia, nodular lesions and scaly skin. Prevalence rate of 35% was obtained fromthe  study.Keywords: Demodicosis, Prevalence, Nigeria mongrel, Pruitus, Dog, Veterinary Services