Experimental and numerical investigation of friction-induced vibration of a beam-on-beam in contact with friction

International audienceThe vibrations generated by friction are responsible for various noises such as squealing, squeaking and chatter. Although these phenomena have been studied for a long time, it is not well-understood. In this study, an experimental and numerical study of friction-induced vibrations of a system composed of two beams in contact is proposed. The experimental system exhibits periodic steady state vibrations of different types. To model and understand this experimental vibratory phenomenon, complex eigenvalue and dynamic transient analyses are performed. In the linear complex eigenvalue analysis, flutter instability occurs via the coalescence of two eigenmodes of the system. This linear study provides an accurate value of the experimental frequency of vibration. To understand what happens physically during friction-induced instability, a dynamic transient analysis that takes account of the non-linear aspect of a frictional contact is performed. In this analysis, friction-induced instability is characterized by self-sustained vibrations and by stick, slip and separation zones occurring at the surface of the contact. The results stemming from this analysis show that good correlation between numerical and experimental vibrations can be obtained (in time and frequency domains). Moreover, time domain simulations permit understanding the physical phenomena involved in two different vibratory behaviours observed experimentally. (C) 2010 Elsevier Ltd. All rights reserved

Instabilités de frottement : Approches temporelle et fréquentielle

International audienceThe vibrations generated at the interface between the two bodies in friction are responsible for various noises such as squealing, juddering, hammering, hooting, etc... In order to model and understand friction-induced vibration phenomenon, two approaches are compared in this article: temporal approach and modal approach. This analysis has been made on a simplified system composed of two beams in contact. The two different approaches have been programmed using Finite Element method. Assumptions on the contact calculation are different for the two approaches. Modal approach consists in calculating eigenvalues of the friction coupled system. Instabilities appear when a pair of modes merges. Eigenvalues with positive real parts are identified as potentially unstable modes. Temporal approach calculates the evolution of displacements, velocities, accelerations, forces ... One speaks about instabilities when stick or separation zones appear in the contact surfaces. With this approach frequencies which are excited during instability are obtained. Results have been compared and both methods give coherent and complementary results

Apports des méthodes fréquentielle et temporelle dans l'étude des instabilités de frottement responsables du crissement

International audienceIn order to model and understand friction-induced vibration phenomenon, two approaches are compared in this article: temporal approach and modal approach. This analysis has been made on a simplified system composed of two beams in contact. Modal approach consists in calculating eigenvalues of the friction coupled system. Instabilities appear when a pair of modes merges. Eigenvalues with positive real parts are identified as potentially unstable modes. Temporal approach calculates the evolution of displacements, velocities, accelerations, forces ... One speaks about instabilities when stick or separation zones appear in the contact surfaces. With this approach frequencies which are excited during instability are obtained. Results have been compared and both methods give coherent and complementary results

Friction-induced instabilities: modal, transient analysis and experimental validation

International audienceThe vibrations generated at the interface between the two bodies in friction are responsible for various noises such as squealing, juddering, hammering, hooting, etc. In order to model and understand friction-induced vibration phenomenon, two types of analysis, modal analysis and transient analysis, are compared in this article. This study has been made on a simplified system composed of two beams in contact. In modal analysis, instabilities appear when a pair of modes merges. Eigenvalues with positive real parts are identified as potentially unstable modes. In transient analysis, one speaks about instabilities when stick or separation zones appear in the contact surfaces. Results have been compared and both analysis give coherent and complementary results. An experimental validation has been made and shows a good correlation between experimental and numerical results

2016 update of the EULAR recommendations for the management of early arthritis

Objectives: Since the 2007 recommendations for the management of early arthritis have been presented, considerable research has been published in the field of early arthritis, mandating an update of the 2007 EULAR recommendations for management of early arthritis. Methods: In accordance with the 2014 EULAR Standardised Operating Procedures, the expert committee pursued an approach that was based on evidence in the literature and on expert opinion. The committee involved 20 rheumatologists, 2 patients and 1 health professional representing 12 European countries. The group defined the focus of the expert committee and target population, formulated a definition of “management” and selected the research questions. A systematic literature research (SLR) was performed by 2 fellows with the help of a skilled librarian. A set of draft recommendations was proposed on the basis of the research questions and the results of the SLR. For each recommendation the categories of evidence were identified, the strength of recommendations was derived and the level of agreement was determined through a voting process. Results: The updated recommendations comprise 3 overarching principles and 12 recommendations for managing early arthritis. The selected statements involve the recognition of arthritis, referral, diagnosis, prognostication, treatment (information, education, pharmacological and non-pharmacological interventions), monitoring and strategy. Eighteen items were identified as relevant for future research. Conclusion: These recommendations provide rheumatologists, general practitioners, health professionals, patients and other stakeholders with an updated EULAR consensus on the entire management of early arthritis

EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2016 update

Recent insights in rheumatoid arthritis (RA) necessitated updating the European League Against Rheumatism (EULAR) RA management recommendations. A large international Task Force based decisions on evidence from 3 systematic literature reviews, developing 4 overarching principles and 12 recommendations (vs 3 and 14, respectively, in 2013). The recommendations address conventional synthetic (cs) disease-modifying antirheumatic drugs (DMARDs) (methotrexate (MTX), leflunomide, sulfasalazine); glucocorticoids (GC); biological (b) DMARDs (tumour necrosis factor (TNF)-inhibitors (adalimumab, certolizumab pegol, etanercept, golimumab, infliximab), abatacept, rituximab, tocilizumab, clazakizumab, sarilumab and sirukumab and biosimilar (bs) DMARDs) and targeted synthetic (ts) DMARDs (Janus kinase (Jak) inhibitors tofacitinib, baricitinib). Monotherapy, combination therapy, treatment strategies (treat-to-target) and the targets of sustained clinical remission (as defined by the American College of Rheumatology-(ACR)-EULAR Boolean or index criteria) or low disease activity are discussed. Cost aspects were taken into consideration. As first strategy, the Task Force recommends MTX (rapid escalation to 25 mg/week) plus short-term GC, aiming at >50% improvement within 3 and target attainment within 6 months. If this fails stratification is recommended. Without unfavourable prognostic markers, switching to—or adding—another csDMARDs (plus short-term GC) is suggested. In the presence of unfavourable prognostic markers (autoantibodies, high disease activity, early erosions, failure of 2 csDMARDs), any bDMARD (current practice) or Jak-inhibitor should be added to the csDMARD. If this fails, any other bDMARD or tsDMARD is recommended. If a patient is in sustained remission, bDMARDs can be tapered. For each recommendation, levels of evidence and Task Force agreement are provided, both mostly very high. These recommendations intend informing rheumatologists, patients, national rheumatology societies, hospital officials, social security agencies and regulators about EULAR's most recent consensus on the management of RA, aimed at attaining best outcomes with current therapies

Value of ultrasonography as a marker of early response to abatacept in patients with rheumatoid arthritis and an inadequate response to methotrexate: results from the APPRAISE study

Objectives: To study the responsiveness of a combined power Doppler and greyscale ultrasound (PDUS) score for assessing synovitis in biologic-naïve patients with rheumatoid arthritis (RA) starting abatacept plus methotrexate (MTX). Methods: In this open-label, multicentre, single-arm study, patients with RA (MTX inadequate responders) received intravenous abatacept (∼10 mg/kg) plus MTX for 24 weeks. A composite PDUS synovitis score, developed by the Outcome Measures in Rheumatology–European League Against Rheumatism (OMERACT–EULAR)-Ultrasound Task Force, was used to evaluate individual joints. The maximal score of each joint was added into a Global OMERACT–EULAR Synovitis Score (GLOESS) for bilateral metacarpophalangeal joints (MCPs) 2–5 (primary objective). The value of GLOESS containing other joint sets was explored, along with clinical efficacy. Results: Eighty-nine patients completed the 24-week treatment period. The earliest PDUS sign of improvement in synovitis was at week 1 (mean change in GLOESS (MCPs 2–5): −0.7 (95% CIs −1.2 to −0.1)), with continuous improvement to week 24. Early improvement was observed in the component scores (power Doppler signal at week 1, synovial hyperplasia at week 2, joint effusion at week 4). Comparable changes were observed for 22 paired joints and minimal joint subsets. Mean Disease Activity Score 28 (C reactive protein) was significantly reduced from weeks 1 to 24, reaching clinical meaningful improvement (change ≥1.2) at week 8. Conclusions: In this first international prospective study, the composite PDUS score is responsive to abatacept. GLOESS demonstrated the rapid onset of action of abatacept, regardless of the number of joints examined. Ultrasound is an objective tool to monitor patients with RA under treatment. Trial registration number: NCT00767325

Rapport au savoir, cultures disciplinaires et pratiques d’études à l’université

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