The death of massive stars - I. Observational constraints on the progenitors of type II-P supernovae

We present the results of a 10.5 yr, volume limited (28 Mpc) search for supernova (SN) progenitor stars. We compile all SNe discovered within this volume (132, of which 27% are type Ia) and determine the relative rates of each sub-type from literature studies : II-P (59%), Ib/c (29%), IIb (5%), IIn (4%) and II-L (3%). Twenty II-P SNe have high quality optical or near-IR pre-explosion images that allow a meaningful search for the progenitor stars. In five cases they are clearly red supergiants, one case is unconstrained, two fall on compact coeval star clusters and the other twelve have no progenitor detected. We review and update all the available data for the host galaxies (distance, metallicity and extinction) and determine masses and upper mass estimates using the STARS stellar evolutionary code and a single consistent homogeneous method. A maximum likelihood calculation suggests that the minimum stellar mass for a type II-P to form is m(min)=8.5 +1/-1.5 Msol and the maximum mass for II-P progenitors is m(max)=16.5 +/- 1.5 Msol, assuming a Salpeter initial mass function (in the range Gamma = -1.35 +0.3/-0.7). The minimum mass is consistent with current estimates for white dwarf progenitor masses, but the maximum mass does not appear consistent with massive star populations. Red supergiants in the Local Group have masses up to 25Msol and the minimum mass to produce a Wolf-Rayet star in single star evolution (between solar and LMC metallicity) is similarly 25-30 Msol. We term this discrepancy the "red supergiant problem" and speculate that these stars could have core masses high enough to form black holes and SNe which are too faint to have been detected. Low luminosity SNe with low 56Ni production seem to arise from explosions of low mass progenitors near the mass threshold for core-collapse. (abridged).Comment: 37 pages, 9 figs, accepted for publication in MNRA

2023 Roadmap on ammonia as a carbon-free fuel

The 15 short chapters that form this 2023 ammonia-for-energy roadmap provide a comprehensive assessment of the current worldwide ammonia landscape and the future opportunities and associated challenges facing the use of ammonia, not only in the part that it can play in terms of the future displacement of fossil-fuel reserves towards massive, long-term, carbon-free energy storage and heat and power provision, but also in its broader holistic impacts that touch all three components of the future global food-water-energy nexus

Pleiotropic Effects of Sox2 during the Development of the Zebrafish Epithalamus

The zebrafish epithalamus is part of the diencephalon and encompasses three major components: the pineal, the parapineal and the habenular nuclei. Using sox2 knockdown, we show here that this key transcriptional regulator has pleiotropic effects during the development of these structures. Sox2 negatively regulates pineal neurogenesis. Also, Sox2 is identified as the unknown factor responsible for pineal photoreceptor prepatterning and performs this function independently of the BMP signaling. The correct levels of sox2 are critical for the functionally important asymmetrical positioning of the parapineal organ and for the migration of parapineal cells as a coherent structure. Deviations from this strict control result in defects associated with abnormal habenular laterality, which we have documented and quantified in sox2 morphants

A Gene Knock-Down Approach in <i>Tribolium castaneum</i> to Study Survival and Priming Towards <i>Bacillus thuringiensis</i> var. <i>tenebrionis</i>

Lindeza AS, Barth K, Kurtz J, Zanchi C. A Gene Knock-Down Approach in &lt;i&gt;Tribolium castaneum&lt;/i&gt; to Study Survival and Priming Towards &lt;i&gt;Bacillus thuringiensis&lt;/i&gt; var. &lt;i&gt;tenebrionis&lt;/i&gt;. Preprints.org. 2021.Insects possess an array of defense molecules allowing them to fight infections. They can also show a form of immune memory, named priming. However, the involvement of insect immune defense mechanisms in priming is unclear, since invertebrates lack the molecular machinery present in vertebrates to build an immune memory. In the red flour beetle Tribolium castaneum, larvae can be primed via the oral route with Bacillus thurigiensis var. tenebrionids (Btt). This results in changes in the expression of a large number of genes, among which some belong to families of ancient defense genes. In the present work, we tested whether three chosen candidate genes (a Thaumatin, a C-type Lectin and an Osiris-like gene) could be involved in the survival to a Btt exposure, as well as in the priming phenotype. We assessed changes in their expression over time and according to the priming treatment, knocked them down individually by RNA interference (RNAi), and observed how it affected survival upon challenge. The quantification of gene expression patterns in our larvae with RT-qPCR showed that up- and/or down-regulation of the genes, after the priming treatment, was quite volatile and time dependent. Upon knock-down, we did not observe the expected decrease in survival to Btt or the abolishment of the priming phenotype. We conclude that knocking down genes individually is probably insufficient to affect survival and priming in our system. This gives us insight into the complexity of the molecular processes underpinning priming