28 research outputs found

    An Analysis of Masked Bobwhite Collection Locales and Habitat Characteristics

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    We evaluated the collecting locales of 251 masked bobwhite (Colinus virginianus ridgwayi) specimens in museum collections. Eighteen were from 4 sites in Arizona—all collected by Herbert Brown. The vast majority (93%) of specimens were from the Mexican State of Sonora. We visited and photographed each of the Arizona collection locations and most of the sites in Sonora. Collector descriptions indicate the bird’s principal habitat affiliations were with tall grass-weed (1⁄4 forb) pastures, savannas, and farm fields. All historic localities visited were either in grass-forb habitats along drainages or in present or former savannas adjacent to woody cover and/or agricultural fields between 240 and 1,060 m elevation. These sites were remarkably similar to other bobwhite habitats in subtropic-tropic South Texas and Oaxaca, Mexico. Masked bobwhite habitat was a diverse tropic-subtropic grassland within or adjacent to dense woody cover (thornscrub) and/or farmland. These habitats experienced alterations and loss of the tall grass-weed component due to livestock husbandry. Some former habitat sites appear to have recovered, however, and restoration of the subspecies might be possible if suitable stock exists. Unfortunately, this bird may now be functionally extinct

    Geographic Distribution: \u3ci\u3eAnolis sagrei\u3c/i\u3e (Brown Anole). USA: Arizona.

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    We discovered the first distributional records for the exotic, Caribbean lizard, Anolis sagrei (Brown Anole), in Arizona

    Search for anomalous t t-bar production in the highly-boosted all-hadronic final state

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    A search is presented for a massive particle, generically referred to as a Z', decaying into a t t-bar pair. The search focuses on Z' resonances that are sufficiently massive to produce highly Lorentz-boosted top quarks, which yield collimated decay products that are partially or fully merged into single jets. The analysis uses new methods to analyze jet substructure, providing suppression of the non-top multijet backgrounds. The analysis is based on a data sample of proton-proton collisions at a center-of-mass energy of 7 TeV, corresponding to an integrated luminosity of 5 inverse femtobarns. Upper limits in the range of 1 pb are set on the product of the production cross section and branching fraction for a topcolor Z' modeled for several widths, as well as for a Randall--Sundrum Kaluza--Klein gluon. In addition, the results constrain any enhancement in t t-bar production beyond expectations of the standard model for t t-bar invariant masses larger than 1 TeV.Comment: Submitted to the Journal of High Energy Physics; this version includes a minor typo correction that will be submitted as an erratu

    Exploring transcriptional regulators Ref-1 and STAT3 as therapeutic targets in malignant peripheral nerve sheath tumours

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    Background MPNST is a rare soft-tissue sarcoma that can arise from patients with NF1. Existing chemotherapeutic and targeted agents have been unsuccessful in MPNST treatment, and recent findings implicate STAT3 and HIF1-α in driving MPNST. The DNA-binding and transcriptional activity of both STAT3 and HIF1-α is regulated by Redox factor-1 (Ref-1) redox function. A first-generation Ref-1 inhibitor, APX3330, is being tested in cancer clinical trials and could be applied to MPNST. Methods We characterised Ref-1 and p-STAT3 expression in various MPNST models. Tumour growth, as well as biomarkers of apoptosis and signalling pathways, were measured by qPCR and western blot following treatment with inhibitors of Ref-1 or STAT3. Results MPNSTs from Nf1-Arfflox/floxPostnCre mice exhibit significantly increased positivity of p-STAT3 and Ref-1 expression when malignant transformation occurs. Inhibition of Ref-1 or STAT3 impairs MPNST growth in vitro and in vivo and induces apoptosis. Genes highly expressed in MPNST patients are downregulated following inhibition of Ref-1 or STAT3. Several biomarkers downstream of Ref-1 or STAT3 were also downregulated following Ref-1 or STAT3 inhibition. Conclusions Our findings implicate a unique therapeutic approach to target important MPNST signalling nodes in sarcomas using new first-in-class small molecules for potential translation to the clinic

    Integrated motor drives: state of the art and future trends

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    With increased need for high power density, high efficiency and high temperature capabilities in Aerospace and Automotive applications, Integrated Motor Drives (IMD) offers a potential solution. However, close physical integration of the converter and the machine may also lead to an increase in components temperature. This requires careful mechanical, structural and thermal analysis; and design of the IMD system. This paper reviews existing IMD technologies and their thermal effects on the IMD system. The effects of the power electronics (PE) position on the IMD system and its respective thermal management concepts are also investigated. The challenges faced in designing and manufacturing of an IMD along with the mechanical and structural impacts of close physical integration is also discussed and potential solutions are provided. Potential converter topologies for an IMD like the Matrix converter, 2-level Bridge, 3-level NPC and Multiphase full bridge converters are also reviewed. Wide band gap devices like SiC and GaN and their packaging in power modules for IMDs are also discussed. Power modules components and packaging technologies are also presented

    Search for microscopic black holes in pp collisions at √s=8 TeV

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    This is the pre-print version of the final published paper that is available from the link below.A search for microscopic black holes and string balls is presented, based on a data sample of pp collisions at √s = 8TeV recorded by the CMS experiment at the Large Hadron Collider and corresponding to an integrated luminosity of 12 fb-1. No excess of events with energetic multiparticle _nal states, typical of black hole production or of similar new physics processes, is observed. Given the agreement of the observations with the expected standard model background, which is dominated by QCD multijet production, 95% con_dence level limits are set on the production of semiclassical or quantum black holes, or of string balls, corresponding to the exclusions of masses below 4.3 to 6.2TeV, depending on model assumptions. In addition, model-independent limits are set on new physics processes resulting in energetic multiparticle _nal states

    Search for narrow resonances and quantum black holes in inclusive and b-tagged dijet mass spectra from pp collisions at √s=7 TeV

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    This is the pre-print version of the Article. The official published version of the Article can be accessed from the links below - Copyright @ 2013 Springer-Verlag.A search for narrow resonances and quantum black holes is performed in inclusive and b-tagged dijet mass spectra measured with the CMS detector at the LHC. The data set corresponds to 5 fb−1 of integrated luminosity collected in pp collisions at √s=7 TeV. No narrow resonances or quantum black holes are observed. Model-independent upper limits at the 95% confidence level are obtained on the product of the cross section, branching fraction into dijets, and acceptance for three scenarios: decay into quark-quark, quark-gluon, and gluon-gluon pairs. Specific lower limits are set on the mass of string resonances (4.31 TeV), excited quarks (3.32 TeV), axigluons and colorons (3.36 TeV), scalar color-octet resonances (2.07 TeV), E6 diquarks (3.75 TeV), and on the masses of W′ (1.92 TeV) and Z′ (1.47 TeV) bosons. The limits on the minimum mass of quantum black holes range from 4 to 5.3 TeV. In addition, b-quark tagging is applied to the two leading jets and upper limits are set on the production of narrow dijet resonances in a model-independent fashion as a function of the branching fraction to b-jet pairs.This study is supported by the BMWF and FWF (Austria); FNRS and FWO (Belgium); CNPq, CAPES, FAPERJ, and FAPESP (Brazil); MES (Bulgaria); CERN; CAS, MoST, and NSFC (China); COLCIENCIAS (Colombia); MSES (Croatia); RPF (Cyprus); MoER, SF0690030s09 and ERDF (Estonia); Academy of Finland, MEC, and HIP (Finland); CEA and CNRS/IN2P3 (France); BMBF, DFG, and HGF (Germany); GSRT (Greece); OTKA and NKTH (Hungary); DAE and DST (India); IPM (Iran); SFI (Ireland); INFN (Italy); NRF and WCU (Korea); LAS (Lithuania); CINVESTAV, CONACYT, SEP, and UASLP-FAI (Mexico); MSI (New Zealand); PAEC (Pakistan); MSHE and NSC (Poland); FCT (Portugal); JINR (Armenia, Belarus, Georgia, Ukraine, Uzbekistan); MON, RosAtom, RAS and RFBr (Russia); MSTD (Serbia); SEIDI and CPAN (Spain); Swiss Funding Agencies (Switzerland); NSC (Taipei); TUBITAK and TAEK (Turkey); STFC (United Kingdom); DOE and NSF (USA)

    Measurement of differential cross sections for the production of a pair of isolated photons in pp collisions at s=7TeV

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    A measurement of differential cross sections for the production of a pair of isolated photons in proton–proton collisions at √s=7TeV is presented. The data sample corresponds to an integrated luminosity of 5.0fb-1 collected with the CMS detector. A data-driven isolation template method is used to extract the prompt diphoton yield. The measured cross section for two isolated photons, with transverse energy above 40 and 25GeV respectively, in the pseudorapidity range |η|0.45, is 17.2±0.2(stat)±1.9(syst)±0.4(lumi)pb. Differential cross sections are measured as a function of the diphoton invariant mass, the diphoton transverse momentum, the azimuthal angle difference between the two photons, and the cosine of the polar angle in the Collins–Soper reference frame of the diphoton system. The results are compared to theoretical predictions at leading, next-to-leading, and next-to-next-to-leading order in quantum chromodynamics

    Research and Science Today No. 2(4)/2012

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    Search for large extra dimensions in the diphoton final state at the Large Hadron Collider

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