Historia de la cirugía vascular contemporanea

Tesis Univ. Complutense.Fac. de MedicinaTRUEProQuestpu

Analysis of Particulate Matter Concentration Intercepted by Trees of a Latin-American Megacity

Restrictions apply to the availability of these data. Data was obtained from Red de Monitoreo de Calidad del Aire de Bogotá (RMCAB) and Botanical Garden of Bogotá (JBB), and are available at http://201.245.192.252:81/Report/stationreport (accessed on 6 February 2020) and http://sigau.jbb.gov.co/SigauJBB/VisorPublico/VisorPublico (accessed on 6 February 2020) with the permission of RMCAB and JBB, respectively.[Abstract] Urban areas with trees provide several ecosystem services to citizens. There is a growing interest in ecosystem services for the removal of air pollutants such as particulate matter. The objective of this paper is to show a study on the variation of intercepted particulate matter concentration (IPMC) by tree leaves in the megacity of Bogotá (Colombia). The relationship between IPMC and PM2.5 concentrations observed in air quality stations in two urban zones with different air pollutions was studied. Influences of climate and leaf morphology variables on IPMC were also analyzed. The species under study were Ligustrum-lucidum, Eucalyptus-ficifolia, Tecoma-stans, Callistemon-citrinus, Lafoensia-acuminata, and Quercus-humboldtii. The results showed that leaf IPMC decreased as the PM2.5 concentration increased. Species that best described this trend were Ligustrum-lucidum and Lafoensia-acuminata. These two species also showed the largest IPMC in their leaves. Indeed, species that showed the largest leaf area were those with the highest IPMC. On average, it was observed that for each 5.0 µg/m3 increase in PM2.5 concentration the IPMCs of the species Ligustrum-lucidum and Lafoensia-acuminata decreased by 33.6% and 23.1%, respectively. When wind speed increased, there was also an increase in PM2.5 concentrations and a reduction in the leaf IPMCs.http://201.245.192.252:81/Report/stationreporthttp://sigau.jbb.gov.co/SigauJBB/VisorPublico/VisorPublic

Más que minería de procesos y predicción de comportamientos. Un nuevo enfoque.

Consecuentemente con el auge y avance tecnológico de la computación, ha aumentado la limitación en el análisis manual de los datos. Diariamente, los sistemas de información almacenan grandes cantidades de eventos respectivos a los procesos que representan. Esta situación, motivó a los investigadores para buscar nuevas alternativas. Como resultado surge la minería de procesos, con un gran impacto en el mundo organizacional. Esta disciplina, tiene como objetivo extraer información no trivial, en procesos de un variado dominio de aplicaciones. En esta rama, diversas técnicas han sido desarrolladas para modelar, extender y monitorear procesos. Uno de los logros fundamentales de la minería de procesos lo constituye el modelo Auditoría 2.0. Unificando la mayoría de los resultados obtenidos en esta disciplina, Auditoría 2.0 cambia sustancialmente el rol de los auditores. No obstante, los resultados escasos en algunas áreas de la minería de procesos, limitan la puesta en práctica de esta estrategia. Por ejemplo, en la predicción de comportamientos, siendo una de las áreas menos explotada dentro de la disciplina. La motivación fundamental de la investigación se enfoca precisamente en esta problemática. El estudio realizado, se centra en las limitaciones de la predicción de comportamientos. En ese sentido, la primera etapa está dedicada al análisis general de la minería de procesos. Se demuestra, el desequilibrio existente entre las etapas fundamentales de esta rama y las etapas aisladas. Finalmente, se realiza un análisis crítico de variadas técnicas de aprendizaje de máquinas que pueden ser utilizadas en la problemática detectada

VITAL phase 2 study: Upfront 5-fluorouracil, mitomycin-C, panitumumab and radiotherapy treatment in nonmetastatic squamous cell carcinomas of the anal canal (GEMCAD 09-02)

Aim: VITAL, a phase II single-arm study, aimed to evaluate efficacy and safety of panitumumab addition to 5-fluorouracil (5-FU), mitomycin-C (MMC) and radiotherapy (RT) in patients with localized squamous cell carcinoma of the anal canal (SCCAC). Methods: Adult, treatment-naïve SCCAC patients (Stage T2-T4, any N, M0) and ECOG-PS ≤2, received panitumumab (6 mg/kg, day 1 and Q2W; 8 weeks), 5-FU (1000 mg/m2/d, days 1-4 and 29-32), MMC (10 mg/m2, days 1 and 29) and RT 45 Gy (1.8 Gy/fraction) to the primary tumor and mesorectal, iliac and inguinal lymph nodes, plus 10-15 Gy boost dose to the primary tumor and affected lymph nodes. The primary objective was disease free survival rate (DFS) at 3-years (expected 3-year DFS rate: 73.7 ± 12%). Results: Fifty-eight patients (31 women; median age: 59 years; ECOG-PS 0-1:98%; TNM II [29%] (T2 or T3/N0/M0)/IIIA (T1-T3/N1/M0 or T4/N0/M0) [21%]/IIIB (T4/N1/M0 or any T/N2 or N3/M0) [47%]/nonevaluable [4%]) were included. The median follow-up was 45 months. The 3-year DFS rate was 61.1% (95% CI: 47.1, 72.4). The 3-year overall survival rate was 78.4% (95% CI: 65.1, 87.1). Eighteen patients (31.0%) required a colostomy within 2 years posttreatment. Grade 3-4 toxicities were experienced by 53 (91%) patients. Most common grade 3-4 treatment-related events were radiation skin injury (40%) and neutropenia (24%). No toxic deaths occurred. Improved efficacy in colostomy-free survival and complete response rate was observed in human papilloma virus positive patients. Conclusions: Panitumumab addition to MMC-5FU regimen in SCCAC patients increases toxicity and does not improve patients’ outcomes. RT plus MMC-5FU remains the standard of care for localized SCCAC patients.This work was supported by Amgen S.A

Galaxy clusters and groups in the ALHAMBRA Survey

We present a catalogue of 348 galaxy clusters and groups with $0.2<z<1.2$ selected in the 2.78 $deg^2$ ALHAMBRA Survey. The high precision of our photometric redshifts, close to $1\%$, and the wide spread of the seven ALHAMBRA pointings ensure that this catalogue has better mass sensitivity and is less affected by cosmic variance than comparable samples. The detection has been carried out with the Bayesian Cluster Finder (BCF), whose performance has been checked in ALHAMBRA-like light-cone mock catalogues. Great care has been taken to ensure that the observable properties of the mocks photometry accurately correspond to those of real catalogues. From our simulations, we expect to detect galaxy clusters and groups with both $70\%$ completeness and purity down to dark matter halo masses of $M_h\sim3\times10^{13}\rm M_{\odot}$ for $z<0.85$. Cluster redshifts are expected to be recovered with $\sim0.6\%$ precision for $z<1$. We also expect to measure cluster masses with $\sigma_{M_h|M^*_{CL}}\sim0.25-0.35\, dex$ precision down to $\sim3\times10^{13}\rm M_{\odot}$, masses which are $50\%$ smaller than those reached by similar work. We have compared these detections with previous optical, spectroscopic and X-rays work, finding an excellent agreement with the rates reported from the simulations. We have also explored the overall properties of these detections such as the presence of a colour-magnitude relation, the evolution of the photometric blue fraction and the clustering of these sources in the different ALHAMBRA fields. Despite the small numbers, we observe tentative evidence that, for a fixed stellar mass, the environment is playing a crucial role at lower redshifts (z$<$0.5).Comment: Accepted for publication in MNRAS. Catalogues and figures available online and under the following link: http://bascaso.net46.net/ALHAMBRA_clusters.htm

The impact from survey depth and resolution on the morphological classification of galaxies

We consistently analyse for the first time the impact of survey depth and spatial resolution on the most used morphological parameters for classifying galaxies through non-parametric methods: Abraham and Conselice-Bershady concentration indices, Gini, M20moment of light, asymmetry, and smoothness. Three different non-local data sets are used, Advanced Large Homogeneous Area Medium Band Redshift Astronomical (ALHAMBRA) and Subaru/XMMNewton Deep Survey (SXDS, examples of deep ground-based surveys), and Cosmos Evolution Survey (COSMOS, deep space-based survey). We used a sample of 3000 local, visually classified galaxies, measuring their morphological parameters at their real redshifts (z ~ 0). Then we simulated them to match the redshift and magnitude distributions of galaxies in the non-local surveys. The comparisons of the two sets allow us to put constraints on the use of each parameter for morphological classification and evaluate the effectiveness of the commonly used morphological diagnostic diagrams. All analysed parameters suffer from biases related to spatial resolution and depth, the impact of the former being much stronger. When including asymmetry and smoothness in classification diagrams, the noise effects must be taken into account carefully, especially for ground-based surveys. M20 is significantly affected, changing both the shape and range of its distribution at all brightness levels. We suggest that diagnostic diagrams based on 2-3 parameters should be avoided when classifying galaxies in ground-based surveys, independently of their brightness; for COSMOS they should be avoided for galaxies fainter than F814 = 23.0. These results can be applied directly to surveys similar to ALHAMBRA, SXDS and COSMOS, and also can serve as an upper/lower limit for shallower/deeper ones.Ministerio de Economía y Competitividad AYA2010-15169, AYA2013-42227-P, AYA2013-4318

The state of the Martian climate

60°N was +2.0°C, relative to the 1981–2010 average value (Fig. 5.1). This marks a new high for the record. The average annual surface air temperature (SAT) anomaly for 2016 for land stations north of starting in 1900, and is a significant increase over the previous highest value of +1.2°C, which was observed in 2007, 2011, and 2015. Average global annual temperatures also showed record values in 2015 and 2016. Currently, the Arctic is warming at more than twice the rate of lower latitudes

Predictors of Response to Exclusive Enteral Nutrition in Newly Diagnosed Crohn´s Disease in Children: PRESENCE Study from SEGHNP

Exclusive enteral nutrition (EEN) has been shown to be more effective than corticosteroids in achieving mucosal healing in children with Crohn´s disease (CD) without the adverse effects of these drugs. The aims of this study were to determine the efficacy of EEN in terms of inducing clinical remission in children newly diagnosed with CD, to describe the predictive factors of response to EEN and the need for treatment with biological agents during the first 12 months of the disease. We conducted an observational retrospective multicentre study that included paediatric patients newly diagnosed with CD between 2014–2016 who underwent EEN. Two hundred and twenty-two patients (140 males) from 35 paediatric centres were included, with a mean age at diagnosis of 11.6 ± 2.5 years. The median EEN duration was 8 weeks (IQR 6.6–8.5), and 184 of the patients (83%) achieved clinical remission (weighted paediatric Crohn’s Disease activity index [wPCDAI] 15 mg/L and ileal involvement tended to respond better to EEN. EEN administered for 6–8 weeks is effective for inducing clinical remission. Due to the high response rate in our series, EEN should be used as the first-line therapy in luminal paediatric Crohn’s disease regardless of the location of disease and disease activityS