243 research outputs found
Dealing with cost-push inflation in Latin America: Multi-causality in a context of increased openness and commodity price volatility
Despite recognizing the exogenous, cost-push nature of recent inflationary pressures in Latin America, plus the difficulties faced by monetary authorities in dealing, under such circumstances, with internal and external disequilibria simultaneously, intellectual attention in policy circles remains focused on demand-side issues and policy instruments. This paper develops an eclectic model that has the potential to nest demand-side elements, but focuses on cost-push factors - distributional conflict and propagation mechanisms - as typically addressed by the post-Keynesian-structuralist tradition. In addition to shedding some light on the nature of inflationary pressures as experienced in Latin American countries during the recent commodity boom - in particular South American commodity exporting economies - the paper’s main goal is to portray the policy and instrumental trade-offs faced by policy-makers themselves. By bringing unconventional policy devices into the model (such as direct interventions in commodity markets), we hope to broaden the scope of the conventional macroeconomic policy instruments.Fil: Abeles, Martin. Comisión Económica para América Latina; Argentina. Universidad Nacional de San Martín; ArgentinaFil: Panigo, Demian Tupac. Universidad Metropolitana para la Educación y el Trabajo. Centro de Innovacion de Los Trabajadores; Argentina. Universidad Nacional de La Plata; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Moreno; Argentin
La ruptura epistemológica de Marx: Más allá de la buena y la mala economía política
Revisitar la obra de Marx permite interpretar la historia del pensamiento económico reciente y reflexionar acerca de las condiciones sociales, políticas y culturales en que se desenvuelve la economía política en la actualidad. Una mayor atención a la ruptura epistemológica de Marx con respecto a los «clásicos» puede contribuir a revertir la creciente insularidad de la economía política en el campo de las ciencias sociales y a fortalecer su capacidad crítica.Fil: Abeles, Martin. Universidad Nacional de San Martín. Instituto de Altos Estudios Sociales; ArgentinaFil: Lampa, Roberto. Universidad Nacional de General Sarmiento. Instituto de Industria; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentin
Growth charts for children with Ellis–van Creveld syndrome
Ellis–van Creveld (EvC) syndrome is a congenital malformation syndrome with marked growth retardation. In this study, specific growth charts for EvC patients were derived to allow better follow-up of growth and earlier detection of growth patterns unusual for EvC. With the use of 235 observations of 101 EvC patients (49 males, 52 females), growth charts for males and females from 0 to 20 years of age were derived. Longitudinal and cross-sectional data were collected from an earlier review of growth data in EvC, a database of EvC patients, and from recent literature. To model the growth charts, the GAMLSS package for the R statistical program was used. Height of EvC patients was compared to healthy children using Dutch growth charts. Data are presented both on a scale for age and on a scale for the square root of age. Compared to healthy Dutch children, mean height standard deviation score values for male and female EvC patients were −3.1 and −3.0, respectively. The present growth charts should be useful in the follow-up of EvC patients. Most importantly, early detection of growth hormone deficiency, known to occur in EvC, will be facilitated
Gradient Optics of subwavelength nanofilms
Propagation and tunneling of light through subwavelength photonic barriers,
formed by dielectric layers with continuous spatial variations of dielectric
susceptibility across the film are considered. Effects of giant
heterogeneity-induced non-local dispersion, both normal and anomalous, are
examined by means of a series of exact analytical solutions of Maxwell
equations for gradient media. Generalized Fresnel formulae, visualizing a
profound influence of gradient and curvature of dielectric susceptibility
profiles on reflectance/transmittance of periodical photonic heterostructures
are presented. Depending on the cutoff frequency of the barrier, governed by
technologically managed spatial profile of its refractive index, propagation or
tunneling of light through these barriers are examined. Nonattenuative transfer
of EM energy by evanescent waves, tunneling through dielectric gradient
barriers, characterized by real values of refractive index, decreasing in the
depth of medium, is shown. Scaling of the obtained results for different
spectral ranges of visible, IR and THz waves is illustrated. Potential of
gradient optical structures for design of miniaturized filters, polarizers and
frequency-selective interfaces of subwavelength thickness is considered
Comparison of LFP-Based and Spike-Based Spectro-Temporal Receptive Fields and Cross-Correlation in Cat Primary Auditory Cortex
Multi-electrode array recordings of spike and local field potential (LFP) activity were made from primary auditory cortex of 12 normal hearing, ketamine-anesthetized cats. We evaluated 259 spectro-temporal receptive fields (STRFs) and 492 frequency-tuning curves (FTCs) based on LFPs and spikes simultaneously recorded on the same electrode. We compared their characteristic frequency (CF) gradients and their cross-correlation distances. The CF gradient for spike-based FTCs was about twice that for 2–40 Hz-filtered LFP-based FTCs, indicating greatly reduced frequency selectivity for LFPs. We also present comparisons for LFPs band-pass filtered between 4–8 Hz, 8–16 Hz and 16–40 Hz, with spike-based STRFs, on the basis of their marginal frequency distributions. We find on average a significantly larger correlation between the spike based marginal frequency distributions and those based on the 16–40 Hz filtered LFP, compared to those based on the 4–8 Hz, 8–16 Hz and 2–40 Hz filtered LFP. This suggests greater frequency specificity for the 16–40 Hz LFPs compared to those of lower frequency content. For spontaneous LFP and spike activity we evaluated 1373 pair correlations for pairs with >200 spikes in 900 s per electrode. Peak correlation-coefficient space constants were similar for the 2–40 Hz filtered LFP (5.5 mm) and the 16–40 Hz LFP (7.4 mm), whereas for spike-pair correlations it was about half that, at 3.2 mm. Comparing spike-pairs with 2–40 Hz (and 16–40 Hz) LFP-pair correlations showed that about 16% (9%) of the variance in the spike-pair correlations could be explained from LFP-pair correlations recorded on the same electrodes within the same electrode array. This larger correlation distance combined with the reduced CF gradient and much broader frequency selectivity suggests that LFPs are not a substitute for spike activity in primary auditory cortex
Network-selectivity and stimulus-discrimination in the primary visual cortex : cell-assembly dynamics
Abstract : Visual neurons coordinate their responses in relation to the stimulus; however, the complex
interplay between a stimulus and the functional dynamics of an assembly still eludes
neuroscientists. To this aim, we recorded cell assemblies from multi-electrodes in the primary
visual cortex of anaesthetized cats in response to randomly presented sine-wave drifting gratings
whose orientation tilted in 22.5° steps. Cross-correlograms divulged the functional connections
at all the tested orientations. We show that a cell-assembly discriminates between orientations by
recruiting a ‘salient’ functional network at every presented orientation, wherein, the connections
and their strengths (peak-probabilities in the cross-correlogram) change from one orientation to
another. Within these assemblies, closely tuned neurons exhibited increased connectivity and
connection-strengths than differently tuned neurons. Minimal connectivity between untuned
neurons suggests the significance of neuronal selectivity in assemblies. This study reflects upon
the dynamics of functional connectivity, and brings to the fore the importance of a ‘signature’
functional network in an assembly that is strictly related to a specific stimulus. Apparently, it
points to the fact that an assembly is the major ‘functional unit’ of information processing in
cortical circuits, rather than the individual neurons
Information Transmission in Cercal Giant Interneurons Is Unaffected by Axonal Conduction Noise
What are the fundamental constraints on the precision and accuracy with which nervous systems can process information? One constraint must reflect the intrinsic “noisiness” of the mechanisms that transmit information between nerve cells. Most neurons transmit information through the probabilistic generation and propagation of spikes along axons, and recent modeling studies suggest that noise from spike propagation might pose a significant constraint on the rate at which information could be transmitted between neurons. However, the magnitude and functional significance of this noise source in actual cells remains poorly understood. We measured variability in conduction time along the axons of identified neurons in the cercal sensory system of the cricket Acheta domesticus, and used information theory to calculate the effects of this variability on sensory coding. We found that the variability in spike propagation speed is not large enough to constrain the accuracy of neural encoding in this system
Optimality of Human Contour Integration
For processing and segmenting visual scenes, the brain is required to combine a multitude of features and sensory channels. It is neither known if these complex tasks involve optimal integration of information, nor according to which objectives computations might be performed. Here, we investigate if optimal inference can explain contour integration in human subjects. We performed experiments where observers detected contours of curvilinearly aligned edge configurations embedded into randomly oriented distractors. The key feature of our framework is to use a generative process for creating the contours, for which it is possible to derive a class of ideal detection models. This allowed us to compare human detection for contours with different statistical properties to the corresponding ideal detection models for the same stimuli. We then subjected the detection models to realistic constraints and required them to reproduce human decisions for every stimulus as well as possible. By independently varying the four model parameters, we identify a single detection model which quantitatively captures all correlations of human decision behaviour for more than 2000 stimuli from 42 contour ensembles with greatly varying statistical properties. This model reveals specific interactions between edges closely matching independent findings from physiology and psychophysics. These interactions imply a statistics of contours for which edge stimuli are indeed optimally integrated by the visual system, with the objective of inferring the presence of contours in cluttered scenes. The recurrent algorithm of our model makes testable predictions about the temporal dynamics of neuronal populations engaged in contour integration, and it suggests a strong directionality of the underlying functional anatomy
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The role of the pod in seed development: strategies for manipulating yield
Pods play a key role in encapsulating the developing seeds and protecting them from pests and pathogens. In addition to this protective function, it has been shown that the photosynthetically active pod wall contributes assimilates and nutrients to fuel seed growth. Recent work has revealed that signals originating from the pod may also act to coordinate grain filling and regulate the reallocation of reserves from damaged seeds to those that have retained viability. In this review we consider the evidence that pods can regulate seed growth and maturation, particularly in members of the Brassicaceae family, and explore how the timing and duration of pod development might be manipulated to enhance either the quantity of crop yield or its nutritional properties
A Model of Late Long-Term Potentiation Simulates Aspects of Memory Maintenance
Late long-term potentiation (L-LTP) appears essential for the formation of
long-term memory, with memories at least partly encoded by patterns of
strengthened synapses. How memories are preserved for months or years, despite
molecular turnover, is not well understood. Ongoing recurrent neuronal
activity, during memory recall or during sleep, has been hypothesized to
preferentially potentiate strong synapses, preserving memories. This hypothesis
has not been evaluated in the context of a mathematical model representing
biochemical pathways important for L-LTP. I incorporated ongoing activity into
two such models: a reduced model that represents some of the essential
biochemical processes, and a more detailed published model. The reduced model
represents synaptic tagging and gene induction intuitively, and the detailed
model adds activation of essential kinases by Ca. Ongoing activity was modeled
as continual brief elevations of [Ca]. In each model, two stable states of
synaptic weight resulted. Positive feedback between synaptic weight and the
amplitude of ongoing Ca transients underlies this bistability. A tetanic or
theta-burst stimulus switches a model synapse from a low weight to a high
weight stabilized by ongoing activity. Bistability was robust to parameter
variations. Simulations illustrated that prolonged decreased activity reset
synapses to low weights, suggesting a plausible forgetting mechanism. However,
episodic activity with shorter inactive intervals maintained strong synapses.
Both models support experimental predictions. Tests of these predictions are
expected to further understanding of how neuronal activity is coupled to
maintenance of synaptic strength.Comment: Accepted to PLoS One. 8 figures at en
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