637 research outputs found
Menopause accelerates biological aging
- Author
- Publication venue
- NATL ACAD SCIENCES
- Publication date
- 26/07/2016
- Field of study
Although epigenetic processes have been linked to aging and disease in other systems, it is not yet known whether they relate to reproductive aging. Recently, we developed a highly accurate epigenetic biomarker of age (known as the “epigenetic clock”), which is based on DNA methylation levels. Here we carry out an epigenetic clock analysis of blood, saliva, and buccal epithelium using data from four large studies: the Women's Health Initiative (n = 1,864); Invecchiare nel Chianti (n = 200); Parkinson's disease, Environment, and Genes (n = 256); and the United Kingdom Medical Research Council National Survey of Health and Development (n = 790). We find that increased epigenetic age acceleration in blood is significantly associated with earlier menopause (P = 0.00091), bilateral oophorectomy (P = 0.0018), and a longer time since menopause (P = 0.017). Conversely, epigenetic age acceleration in buccal epithelium and saliva do not relate to age at menopause; however, a higher epigenetic age in saliva is exhibited in women who undergo bilateral oophorectomy (P = 0.0079), while a lower epigenetic age in buccal epithelium was found for women who underwent menopausal hormone therapy (P = 0.00078). Using genetic data, we find evidence of coheritability between age at menopause and epigenetic age acceleration in blood. Using Mendelian randomization analysis, we find that two SNPs that are highly associated with age at menopause exhibit a significant association with epigenetic age acceleration. Overall, our Mendelian randomization approach and other lines of evidence suggest that menopause accelerates epigenetic aging of blood, but mechanistic studies will be needed to dissect cause-and-effect relationships further
Coordination and resource-related difficulties encountered by Quebec's public health specialists and infectious diseases/medical microbiologists in the management of A (H1N1) - a mixed-method, exploratory survey
- Author
- Publication venue
- BioMed Central
- Publication date
- 01/01/2012
- Field of study
<p>Abstract</p> <p>Background</p> <p>In Quebec, the influenza A (H1N1) pandemic was managed using a top-down style that left many involved players with critical views and frustrations. We aimed to describe physicians' perceptions - infectious diseases specialists/medical microbiologists (IDMM) and public health/preventive medicine specialists (PHPMS) - in regards to issues encountered with the pandemics management at the physician level and highlight suggested improvements for future healthcare emergencies.</p> <p>Methods</p> <p>In April 2010, Quebec IDMM and PHPMS physicians were invited to anonymously complete a web-based learning needs assessment. The survey included both open-ended and multiple-choice questions. Descriptive statistics were used to report on the frequency distribution of multiple choice responses whereas thematic content analysis was used to analyse qualitative data generated from the survey and help understand respondents' experience and perceptions with the pandemics.</p> <p>Results</p> <p>Of the 102 respondents, 85.3% reported difficulties or frustrations in their practice during the pandemic. The thematic analysis revealed two core themes describing the problems experienced in the pandemic management: coordination and resource-related difficulties. Coordination issues included communication, clinical practice guidelines, decision-making, roles and responsibilities, epidemiological investigation, and public health expert advisory committees. Resources issues included laboratory resources, patient management, and vaccination process.</p> <p>Conclusion</p> <p>Together, the quantitative and qualitative data suggest a need for improved coordination, a better definition of roles and responsibilities, increased use of information technologies, merged communications, and transparency in the decisional process. Increased flexibility and less contradiction in clinical practice guidelines from different sources and increased laboratory/clinical capacity were felt critical to the proper management of infectious disease emergencies.</p
Propagation of Epileptiform Events across the Corpus Callosum in a Cingulate Cortical Slice Preparation
- Author
- AA sadi-Pooya
- AJ Trevelyan
- AJ Trevelyan
- AJ Trevelyan
- AL Horne
- AT Berg
- BA Vogt
- BA Vogt
- BA Vogt
- BL Ralston
- Bonnie Quach-Wong
- E Tanaka
- ED Kanter
- EM Marcus
- EM Marcus
- G Aaron
- G Panuccio
- G Panuccio
- GJ Sills
- Gloster Aaron
- Gregory Storch
- H Walther
- HA Swadlow
- HA Swadlow
- I Khalilov
- J Kang
- J Liauw
- J Liauw
- J Musgrave
- Jeffrey Walker
- Jon T. Brown
- Julian Sonnenfeld
- M de Curtis
- M De Curtis
- M Galarreta
- MA Whittington
- O Devinsky
- O Devinsky
- P Sah
- P Sah
- S Cookson
- SS Kumar
- SS Spencer
- SS Spencer
- T Paus
- TC Erickson
- WA Hauser
- WW Anderson
- Y Ben-Ari
- Y Cisse
- Publication venue
- Public Library of Science
- Publication date
- 01/01/2012
- Field of study
We report on a novel mouse in vitro brain slice preparation that contains intact callosal axons connecting anterior cingulate cortices (ACC). Callosal connections are demonstrated by the ability to regularly record epileptiform events between hemispheres (bilateral events). That the correlation of these events depends on the callosum is demonstrated by the bisection of the callosum in vitro. Epileptiform events are evoked with four different methods: (1) bath application of bicuculline (a GABA-A antagonist); (2) bicuculline+MK801 (an NMDA receptor antagonist), (3) a zero magnesium extracellular solution (0Mg); (4) focal application of bicuculline to a single cortical hemisphere. Significant increases in the number of epileptiform events, as well as increases in the ratio of bilateral events to unilateral events, are observed during bath applications of bicuculline, but not during applications of bicuculline+MK-801. Long ictal-like events (defined as events >20 seconds) are only observed in 0Mg. Whole cell patch clamp recordings of single neurons reveal strong feedforward inhibition during focal epileptiform events in the contralateral hemisphere. Within the ACC, we find differences between the rostral areas of ACC vs. caudal ACC in terms of connectivity between hemispheres, with the caudal regions demonstrating shorter interhemispheric latencies. The morphologies of many patch clamped neurons show callosally-spanning axons, again demonstrating intact callosal circuits in this in vitro preparation
A meta-analysis of genome-wide association studies of epigenetic age acceleration
- Author
- A Castaing-Berthou
- A Kundaje
- A Quach
- Ake T. Lu
- Alison D. Murray
- Andrew M. McIntosh
- AP Boyle
- Archie Campbell
- AT Lu
- B Agrawal
- B Bulik-Sullivan
- B Guo
- BC Christensen
- BH Chen
- BH Smith
- BH Smith
- BK Bulik-Sullivan
- C Giambartolomei
- C-H Wang
- C-Y Wu
- CA de Leeuw
- Caroline Hayward
- CJ Willer
- Consortium T 1000 GP
- D Vågerö
- D Welter
- David J. Porteous
- David M. Howard
- DL McCartney
- EA Houseman
- EY Krynetski
- F Aguet
- F Belinky
- FF Fagnoni
- G Hannum
- GJPL Kops
- H Tajima
- Heather C. Whalley
- J Ernst
- J MacArthur
- J Yang
- J Yang
- J Yang
- J Zheng
- John M. Greally
- JR Gibbs
- JT Bell
- JT Bell
- Jude Gibson
- K Nagaoka
- K Ozato
- K Wang
- K Watanabe
- Kathryn L. Evans
- L Rode
- LS Hall
- M Bonafè
- M Kircher
- MA Krasilnikov
- Mairead L. Bermingham
- ME Levine
- ME Levine
- MF Segura
- MP Mattson
- N Zaitlen
- NA Twine
- P Couarch
- R Nagy
- RA Gibbs
- RA Miller
- RE Marioni
- RE Marioni
- RE Marioni
- Riccardo E. Marioni
- RJ Pruim
- Robert F. Hillary
- Rosie M. Walker
- S Beck
- S Horvath
- S Horvath
- S Horvath
- S Jakob
- S Shah
- Steve Horvath
- Stewart W. Morris
- T Niccoli
- Tom C. Russ
- Toni-Kim Clarke
- TR Gaunt
- U Võsa
- V Bollati
- Y Benjamini
- Y Saheki
- Y Shi
- Y-F Chen
- Y-F Chen
- Z Zhu
- Publication venue
- 'Public Library of Science (PLoS)'
- Publication date
- 21/03/2019
- Field of study
Funding: Generation Scotland received core support from the Chief Scientist Office of the Scottish Government Health Directorates (CZD/16/6) and the Scottish Funding Council (HR03006). Genotyping and DNA methylation profiling of the GS samples was carried out by the Genetics Core Laboratory at the Wellcome Trust Clinical Research Facility, Edinburgh, Scotland and was funded by the Medical Research Council UK and the Wellcome Trust (Wellcome Trust Strategic Award “STratifying Resilience and Depression Longitudinally” ((STRADL) Reference 104036/Z/14/Z)). Funding details for the cohorts included in the study by Lu et al. (2018) can be found in their publication. HCW is supported by a JMAS SIM fellowship from the Royal College of Physicians of Edinburgh and by an ESAT College Fellowship from the University of Edinburgh. AMM & HCW acknowledge the support of the Dr. Mortimer and Theresa Sackler Foundation. SH acknowledges support from grant 1U01AG060908-01. REM is supported by Alzheimer’s Research UK major project grant ARUK-PG2017B-10. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. Data Availability: Summary statistics from the research reported in the manuscript will be made available immediately following publication on the Edinburgh Data Share portal with a permanent digital object identifier (DOI). According to the terms of consent for Generation Scotland participants, requests for access to the individual-level data must be reviewed by the GS Access Committee ([email protected]). Individual-level data are not immediately available, due to confidentiality considerations and our legal obligation to protect personal information. These data will, however, be made available upon request and after review by the GS access committee, once ethical and data governance concerns regarding personal data have been addressed by the receiving institution through a Data Transfer Agreement.Peer reviewedPublisher PD
The role of epigenetics in renal ageing
- Author
- A De Sandre-Giovannoli
- A Kataria
- A Parsa
- A Quach
- A Salminen
- A Venkatraman
- AC Aragon
- AC Hofer
- AE Pasquinelli
- AS Levey
- AS Wierzbicki
- AT Geronimus
- B Bartholomew
- B Heinemann
- B Stengel
- BP Lewis
- BS McEwen
- C Braconi
- C Faul
- C Franceschi
- C Koppelstaetter
- C Missailidis
- C Otín
- C Selman
- C-Y Sun
- CE Riera
- CH Kim
- CJ Packard
- CM Shanahan
- CP Au
- CR Burtner
- CW McIntyre
- D Di Bona
- D Hershkovitz
- D McClintock
- D McGuinness
- D McGuinness
- D McGuinness
- DA Ferenbach
- Dagmara McGuinness
- DK Shumaker
- DR Appling
- DR Hodge
- E Londin
- EH Blackburn
- EJ Tomayko
- EM Crimmins
- EM Mercken
- ES Epel
- FG Osorio
- G Der
- G Hannum
- G-H Young
- GT Baker
- H Khalil
- I Beerman
- I Beerman
- I Grammatikakis
- I Sturmlechner
- J Aron-Wisnewsky
- J Chen
- J Grillari
- J Himmelfarb
- J Lara
- J Long
- J Mertens
- JA Brassard
- JC Chillarón
- Jeroen P. Kooman
- JJ Carrero
- JJ Fuster
- JJ Scialla
- JM Lorenzen
- JP Kooman
- K Cao
- K Luttropp
- K Mawlood
- KA Deans
- KA Mather
- KL Yap
- L Christiansen
- L Fontana
- L Perna
- LF Cherkas
- LM McGlynn
- LP Rubin
- M Eriksson
- M Gardner
- M Gingell-Littlejohn
- M Inui
- M Kuro-o
- M Kuro-o
- M Montes
- M Montes
- M Olive
- M Picard
- M Romani
- M Xu
- M Zampieri
- M-C Tsai
- MA Reddy
- Maria Eriksson
- MD Anway
- MP Baar
- MP Gardner
- MR Wing
- MS Cunnington
- MW Robinson
- N Malaquin
- N Panagiotou
- N Tasdemir
- ND Vaziri
- O Zhdanova
- P Buendía
- P Christopher
- P Dominguez-Salas
- P Loher
- P Monnier
- P Sen
- P Stenvinkel
- P Stenvinkel
- P Yi
- Paul G. Shiels
- PD Adams
- PD Gluckman
- Peter Stenvinkel
- PG Shiels
- PG Shiels
- PG Shiels
- PP Shah
- R Cooper
- R McClelland
- R Ramírez
- R Schmitt
- R Thaler
- R Woroniecki
- RC Friedman
- RC Painter
- RD Goldman
- RE Marioni
- RG Nelson
- RJ Simpson
- RP McCord
- S Fichtlscherer
- S Hamed
- S Horvath
- S Horvath
- S Horvath
- S Imai
- S Krauss-Etschmann
- SC Johnson
- SJ Harvey
- SJ Mitchell
- SL Berger
- T Isakova
- T McKenna
- T McKenna
- T Tchkonia
- TH Hostetter
- TJ Roseboom
- U Degirmenci
- W Arancio
- W Bechtel
- W Zhang
- WHW Tang
- WL Lau
- X Han
- X Tan
- Y Kotake
- Y-A Ko
- YN Velupillai
- Z Chen
- Z Wang
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 19/06/2017
- Field of study
An ability to separate natural ageing processes from processes specific to morbidities is required to understand the heterogeneity of age-related organ dysfunction. Mechanistic insight into how epigenetic factors regulate ageing throughout the life course, linked to a decline in renal function with ageing, is already proving to be of value in the analyses of clinical and epidemiological cohorts. Noncoding RNAs provide epigenetic regulatory circuits within the kidney, which reciprocally interact with DNA methylation processes, histone modification and chromatin. These interactions have been demonstrated to reflect the biological age and function of renal allografts. Epigenetic factors control gene expression and activity in response to environmental perturbations. They also have roles in highly conserved signalling pathways that modulate ageing, including the mTOR and insulin/insulin-like growth factor signalling pathways, and regulation of sirtuin activity. Nutrition, the gut microbiota, inflammation and environmental factors, including psychosocial and lifestyle stresses, provide potential mechanistic links between the epigenetic landscape of ageing and renal dysfunction. Approaches to modify the renal epigenome via nutritional intervention, targeting the methylome or targeting chromatin seem eminently feasible, although caution is merited owing to the potential for intergenerational and transgenerational effects
Search for dark matter produced in association with a single top quark or a top quark pair in proton-proton collisions at s=13 TeV
- Author
- Aarrestad TK
- Abbaneo D
- Abbiendi G
- Abbrescia M
- Abdullah WAT Wan
- Abdullin S
- Abdulsalam A
- Abercrombie D
- Abu Zeid S
- Ackert A
- Acosta D
- Acosta JG
- Adam W
- Adams MR
- Adams T
- Adzic P
- Afanasiev S
- Agapitos A
- Agaras MN
- Aggleton R
- Agram J-L
- Ahmad A
- Ahmad M
- Ahmad M
- Ahmed I
- Ahuja S
- Akbiyik M
- Akchurin N
- Akgun B
- Al-Bataineh A
- Albajar C
- Albergo S
- Albert A
- Albrow M
- Alcaraz Maestre J
- Aleksandrov A
- Alexander J
- Alhusseini M
- Ali MAB Md
- Alimena J
- Allen B
- Almond J
- Alvarez Fernandez A
- Alvarez JD Ruiz
- Alverson G
- Alves FL
- Alves GA
- Alyari M
- Amapane N
- Ambrogi F
- Amendola C
- Amin N
- Amsler C
- Anagnostou G
- Anampa K Hurtado
- Anderson D
- Andrea J
- Andreev V
- Andreev Yu
- Andrews MB
- Androsov K
- Angioni L Pinna
- Antonelli L
- Antropov I
- Antunovic Z
- Apanasevich L
- Apollinari G
- Apresyan A
- Apyan A
- Araujo M
- Arcaro D
- Arcidiacono R
- Arenton MW
- Argiro S
- Arndt T
- Arneodo M
- Asavapibhop B
- Asawatangtrakuldee C
- Asghar MI
- Asilar E
- Askew A
- Assran Y
- Atakisi IO
- Ather MW
- Attikis A
- Auffray E
- Aushev T
- Autermann C
- Auzinger G
- Avdeeva E
- Avery P
- Avila C
- Ayala E
- Azarkin M
- Azhgirey I
- Aziz T
- Azzi P
- Azzolini V
- Azzurri P
- Baarmand MM
- Babaev A
- Babounikau I
- Bacchetta N
- Bachiller I
- Bachtis M
- Backhaus M
- Baden A
- Bagliesi G
- Bahinipati S
- Baidali S
- Baillon P
- Bainbridge R
- Bakhshiansohi H
- Bakirci MN
- Ball AH
- Ball F
- Ban Y
- Band R
- Banerjee S
- Banerjee S
- Bani L
- Bansal S
- Barbagli G
- Barberis E
- Bargassa P
- Baringer P
- Barker A
- Barnes VE
- Barney D
- Barnyakov A
- Baron O
- Barone L
- Barria P
- Barrio Luna M
- Bartek R
- Barth C
- Bartok M
- Bartosik N
- Baselga M
- Baskakov A
- Bat A
- Battilana C
- Baty A
- Bauer G
- Bauerdick LAT
- Baur S
- Bayshev I
- Bean A
- Beauceron S
- Beaudette F
- Becerra DA Sanz
- Beernaert K
- Beghin D
- Behera PK
- Behnke O
- Behrens U
- Bein S
- Beirao Da Cruz E Silva C
- Belchior Batista Das Chagas E
- Belforte S
- Bell KW
- Bellan R
- Belloni A
- Belyaev A
- Belyaev A
- Benaglia A
- Benato L
- Bencze G
- Bendavid J
- Benecke A
- Benelli G
- Beni N
- Benitez JF
- Benussi L
- Benvenuti AC
- Beretvas A
- Bergauer T
- Berger P
- Beri SB
- Bernardes CA
- Bernet C
- Berry D
- Berryhill J
- Bertsche D
- Besancon M
- Beschi A
- Betts RR
- Bhandari R
- Bhardwaj A
- Bhardwaj R
- Bharti M
- Bhat MA
- Bhat PC
- Bhatnagar V
- Bhattacharya R
- Bhattacharya S
- Bhattacharya S
- Bhattacharya S
- Bhawandeep U
- Bheesette S
- Bhopatkar V
- Bhowmik D
- Bhowmik S
- Bi R
- Bialkowska H
- Bian JG
- Bianchini L
- Bianco M
- Bianco S
- Biasini M
- Biino C
- Bilei GM
- Bilin B
- Bilki B
- Bin Anuar AA
- Bisello D
- Bitioukov S
- Blanco J Martin
- Blekman F
- Blinov V
- Blobel V
- Bloch D
- Bloch P
- Bloom K
- Bluj M
- Blumenfeld B
- Boccali T
- Bocci A
- Bodek A
- Boimska B
- Boletti A
- Bonacorsi D
- Bondu O
- Boos E
- Boran F
- Boren S
- Borg J
- Borgonovi L
- Bornheim A
- Borras K
- Borrello L
- Bortignon P
- Bose T
- Botta C
- Botta V
- Boudoul G
- Bouhali O
- Bourilkov D
- Bouvier E
- Bowen J
- Bragagnolo A
- Braghieri A
- Braibant-Giacomelli S
- Brainerd C
- Brandstetter J
- Brandt S
- Branson JG
- Bravo C
- Breedon R
- Breeze S
- Brew C
- Brigljevic V
- Brinkerhoff A
- Brivio F
- Brochero Cifuentes JA
- Brochet S
- Brodski M
- Brom J-M
- Brondolin E
- Brooke JJ
- Brown RM
- Brun H
- Bruno G
- Brzhechko D
- Bucci R
- Buccilli A
- Buchanan J
- Buchmuller O
- Bueghly J
- Bundock A
- Bunin P
- Bunkowski K
- Buontempo S
- Burkett K
- Burns D
- Burns D
- Burt K
- Busson P
- Busza W
- Butler JN
- Butler PH
- Butz E
- Bylinkin A
- Bylsma B
- Byszuk A
- Cabrera A
- Cabrillo IJ
- Cadamuro L
- Caillol C
- Cakir A
- Calabria C
- Calderon A
- Cali IA
- Call K
- Calligaris L
- Caminada L
- Campagnari C
- Campanini R
- Campbell A
- Camporesi T
- Candelise V
- Canelli MF
- Canepa A
- Cankocak K
- Capiluppi P
- Cappati A
- Caputo C
- Carlin R
- Carlsmith D
- Carnes A
- Carrera Jarrin E
- Carrillo Montoya CA
- Carrillo Moreno S
- Cartiglia N
- Carvalho W
- Casarsa M
- Caspart R
- Castaldi R
- Castaneda Hernandez A
- Castilla-Valdez H
- Castle J
- Castro A
- Cavallari F
- Cavallo FR
- Cavallo N
- Cavanaugh R
- Ceballos G Gomez
- Cecchi C
- Celik A
- Cenna F
- Cepeda M
- Cerati GB
- Cerci D Sunar
- Cerci S
- Cerminara G
- Cerrada M
- Chabert EC
- Chadeeva M
- Chang P
- Chang P
- Chanon N
- Chao Y
- Chaparro Sierra LF
- Chapon E
- Charaf O
- Charlot C
- Chatterjee K
- Chatterjee RM
- Chatterjee S
- Chauhan S
- Chauhan S
- Chaves J
- Chawla R
- Chazin Quero B
- Checchia P
- Chekhovsky V
- Chen G
- Chen GM
- Chen HS
- Chen KF
- Chen M
- Chen PH
- Chen X
- Chen Y
- Chen Y
- Chen Z
- Chenarani S
- Cheng T
- Cheng Y
- Cherepanov V
- Chernyavskaya N
- Chertok M
- Cheung HWK
- Chhibra SS
- Chierici R
- Chinellato J
- Chlebana F
- Cho S
- Choi S
- Choi Y
- Chou JP
- Choudhary BC
- Choudhury S
- Chowdhury S Roy
- Chu J
- Chudasama R
- Chwalek T
- Ciangottini D
- Cieri D
- Ciocca C
- Ciocci MA
- Cipriani M
- Ciriolo V
- Cirkovic P
- Citron M
- Cittolin S
- Ciulli V
- Civinini C
- Claes DR
- Clare R
- Clarida W
- Clement E
- Clerbaux B
- Cockerill DJA
- Cocoros A
- Codispoti G
- Coelho E
- Colafranceschi S
- Colaleo A
- Cole JE
- Colino N
- Collaboration CMS
- Collard C
- Colling D
- Colombo F
- Cometti S
- Connor P
- Contardo D
- Conte E
- Contreras-Campana C
- Conway J
- Conway R
- Cooper SI
- Cooperstein S
- Cornelis T
- Correia Silva G
- Cossutti F
- Costa M
- Coubez X
- Couderc F
- Coughlan JA
- Courbon B
- Cousins R
- Covarelli R
- Cox B
- Cox PT
- Creanza D
- Cremonesi M
- Cristella L
- Csanad M
- Cucciati G
- Cuevas J
- Cuffiani M
- Cumalat JP
- Curry D
- Cussans D
- Cutts D
- Czellar S
- D'Alessandro R
- D'Alfonso M
- d'Enterria D
- D'Hondt J
- Da Costa EM
- Da Rold A
- Da Silveira GG
- Dabrowski A
- Daci N
- Dalchenko M
- Dall'Osso M
- Dallavalle GM
- Damarseckin S
- Damgov J
- Damiani D Dominguez
- Danilov V
- Daponte V
- Das P
- Das S
- Dasgupta A
- Daskalakis G
- Dasu S
- Datta A
- Dauncey P
- David A
- David P
- Davies G
- Davignon O
- de Barbaro P
- De Boer W
- De Bruyn I
- de Cassagnac R Granier
- De Clercq J
- De Cosa A
- de Fatis T Tabarelli
- De Filippis N
- De Guio F
- De Iorio A
- De Jesus Damiao D
- De La Cruz B
- De La Cruz-Burelo E
- De Lentdecker G
- De Lima R Teixeira
- De Mattia M
- de Monchenault G Hamel
- De Oliveira Martins C
- De Oliveira A Carvalho Antunes
- De Palma M
- De Roeck A
- de Troconiz JF
- De Wit A
- De Wolf EA
- Deelen N
- Defranchis MM
- Deiters K
- Dejardin M
- Del Burgo R
- Del Re D
- Del Valle A Escalante
- Delaere C
- Delannoy AG
- Delannoy H
- Delcourt M
- Delgado Peris A
- Delgado A
- Dell'Orso R
- Della Negra M
- Della Porta G Zevi
- Della Ricca G
- Demaria N
- Demina R
- Demiragli Z
- Demiroglu ZS
- Denegri D
- Depasse P
- Derdzinski M
- Dermenev A
- Deroover K
- Dev N
- Devetak D
- Dewanjee RK
- Dey S
- Dhingra N
- Di Crescenzo A
- Di Croce D
- Di Florio A
- Di Francesco A
- Di Guida S
- Di Marco E
- Di Maria R
- Di Mattia A
- Diemoz M
- Dierlamm A
- Dildick S
- Dilsiz K
- Dimitrov A
- Dimova T
- Dinardo ME
- Dissertori G
- Dittmann J
- Dittmar M
- Dittmer S
- Doan TH
- Dobson M
- Dobur D
- Dodd L
- Dolek F
- Dolen J
- Dominguez A
- Donato S
- Donega M
- Dordevic M
- Dorfer C
- Dorigo T
- Dorney B
- Doroba K
- Dosselli U
- Dozen C
- Dragicevic M
- Dremin I
- Dreyer T
- Duarte Campderros J
- Duarte J
- Dube S
- Dubinin M
- Duchardt D
- Dudenas V
- Dudero PR
- Dudko L
- Dugad S
- Duh YT
- Dulemba JL
- Dunser M
- Dupont N
- Duran-Osuna MC
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- Yusli MN
- Zabi A
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- Zalewski P
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- Zarubin A
- Zarucki M
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- Zenaiev O
- Zenz SC
- Zeuner WD
- Zeyrek M
- Zghiche A
- Zhang A
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- Zolkapli Z
- Zorbakir IS
- Zorbilmez C
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- Zou D
- Zucchetta A
- Zumerle G
- Zuo X
- Zuolo D
- Publication venue
- Publication date
- 01/01/2019
- Field of study
A search has been performed for heavy resonances decaying to ZZ or ZW in 2l2q final states, with two charged leptons (l = e, mu) produced by the decay of a Z boson, and two quarks produced by the decay of a W or Z boson. The analysis is sensitive to resonances with masses in the range from 400 to 4500 GeV. Two categories are defined based on the merged or resolved reconstruction of the hadronically decaying vector boson, optimized for high- and low-mass resonances, respectively. The search is based on data collected during 2016 by the CMS experiment at the LHC in proton-proton collisions with a center-of-mass energy of root s = 13 TeV, corresponding to an integrated luminosity of 35.9 fb(-1). No excess is observed in the data above the standard model background expectation. Upper limits on the production cross section of heavy, narrow spin-1 and spin-2 resonances are derived as a function of the resonance mass, and exclusion limits on the production of W' bosons and bulk graviton particles are calculated in the framework of the heavy vector triplet model and warped extra dimensions, respectively.A search has been performed for heavy resonances decaying to ZZ or ZW in 2l2q final states, with two charged leptons (l = e, mu) produced by the decay of a Z boson, and two quarks produced by the decay of a W or Z boson. The analysis is sensitive to resonances with masses in the range from 400 to 4500 GeV. Two categories are defined based on the merged or resolved reconstruction of the hadronically decaying vector boson, optimized for high- and low-mass resonances, respectively. The search is based on data collected during 2016 by the CMS experiment at the LHC in proton-proton collisions with a center-of-mass energy of root s = 13 TeV, corresponding to an integrated luminosity of 35.9 fb(-1). No excess is observed in the data above the standard model background expectation. Upper limits on the production cross section of heavy, narrow spin-1 and spin-2 resonances are derived as a function of the resonance mass, and exclusion limits on the production of W' bosons and bulk graviton particles are calculated in the framework of the heavy vector triplet model and warped extra dimensions, respectively.A search for dark matter produced in association with top quarks in proton-proton collisions at a center-of-mass energy of 13 TeV is presented. The data set used corresponds to an integrated luminosity of 35.9 fb(-1) recorded with the CMS detector at the LHC. Whereas previous searches for neutral scalar or pseudoscalar mediators considered dark matter production in association with a top quark pair only, this analysis also includes production modes with a single top quark. The results are derived from the combination of multiple selection categories that are defined to target either the single top quark or the top quark pair signature. No significant deviations with respect to the standard model predictions are observed. The results are interpreted in the context of a simplified model in which a scalar or pseudoscalar mediator particle couples to a top quark and subsequently decays into dark matter particles. Scalar and pseudoscalar mediator particles with masses below 290 and 300 GeV, respectively, are excluded at 95% confidence level, assuming a dark matter particle mass of 1 GeV and mediator couplings to fermions and dark matter particles equal to unity.Peer reviewe
Measurement of the top quark forward-backward production asymmetry and the anomalous chromoelectric and chromomagnetic moments in pp collisions at √s = 13 TeV
- Author
- Aarrestad Thea Klaeboe
- Abbaneo Duccio
- Abbiendi Giovanni
- Abbrescia Marcello
- Abdelalim Ahmed Ali
- Abdullin Salavat
- Abercrombie Daniel
- Abu Zeid Shimaa
- Acharya Himal
- Acosta Darin
- Acosta John Gabriel
- Adam Wolfgang
- Adams Mark Raymond
- Adams Todd
- Adzic Petar
- Afanasiev Serguei
- Agapitos Antonis
- Agarwal Garvita
- Aggleton Robin
- Agram Jean-Laurent
- Aguilar-Benitez Manuel
- Ahmad Ashfaq
- Ahmad Muhammad
- Ahmad Muhammad
- Ahuja Sudha
- Akbiyik Melike
- Akchurin Nural
- Akgun Bora
- Albajar Carmen
- Albergo Sebastiano
- Albert Andreas
- Albrow Michael
- Alcaraz Maestre Juan
- Aldaya Martin Maria
- Aleksandrov Aleksandar
- Alexander James
- Alhusseini Mohammad
- Alimena Juliette
- Allen Brandon
- Almond John
- Alvarez Gonzalez Barbara
- Alverson George
- Alves Gilvan
- Aly Reham
- Alyari Maral
- Amapane Nicola
- Ambrogi Federico
- Amendola Chiara
- Amin Nick
- Amsler Claude
- Anagnostou Georgios
- Anderson Dustin
- Andrea Jeremy
- Andreev Vladimir
- Andreev Yuri
- Andrews Michael Benjamin
- Androsov Konstantin
- Antchev Georgy
- Antunovic Zeljko
- Apanasevich Leonard
- Apollinari Giorgio
- Apresyan Artur
- Apyan Aram
- Araujo Mariana
- Arcaro Daniel
- Arcidiacono Roberta
- Arenton Michael Wayne
- Argiro Stefano
- Arneodo Michele
- Asavapibhop Burin
- Asawatangtrakuldee Chayanit
- Asenov Patrick
- Askew Andrew
- Asmuss Paul
- Atakisi Ismail Okan
- Ather Mohsan Waseem
- Attikis Alexandros
- Auffray Etiennette
- Aushev Tagir
- Autermann Christian
- Auzinger Georg
- Avati Valentina
- Avery Paul
- Avila Carlos
- Awan Muhammad Imran Malik
- Ayala Edy
- Azarkin Maksim
- Azhgirey Igor
- Aziz Tariq
- Azzi Patrizia
- Azzurri Paolo
- Baarmand Marc M
- Babaev Anton
- Babounikau Illia
- Bacchetta Nicola
- Bachiller Irene
- Bachtis Michail
- Backhaus Malte
- Baden Drew
- Baechler Joachim
- Bagliesi Giuseppe
- Bahinipati Seema
- Baillon Paul
- Bainbridge Robert
- Bakas Georgios
- Bakhshiansohi Hamed
- Baldenegro Barrera Cristian
- Ball Austin
- Ban Yong
- Band Reyer
- Banerjee Sudeshna
- Banerjee Sunanda
- Bansal Sunil
- Barbagli Giuseppe
- Barberis Emanuela
- Bargassa Pedrame
- Baringer Philip
- Barker Anthony
- Barnes Virgil E
- Barney David
- Barnyakov Alexander
- Baron Owen
- Barria Patrizia
- Barrio Luna Mar
- Bartek Rachel
- Bartosik Nazar
- Bartók Márton
- Baselga Marta
- Baskakov Alexey
- Bastos Diogo
- Bat Ayse
- Battilana Carlo
- Baty Austin
- Bauerdick Lothar AT
- Baur Sebastian
- Bayshev Igor
- Bean Alice
- Beauceron Stephanie
- Beaudette Florian
- Beernaert Kelly
- Beghin Diego
- Behera Prafulla Kumar
- Behnke Olaf
- Behrens Ulf
- Bein Samuel
- Belchior Batista Das Chagas Ewerton
- Belforte Stefano
- Bell Ken W
- Bellan Riccardo
- Belloni Alberto
- Bellora Andrea
- Belyaev Alexander
- Belyaev Andrey
- Benaglia Andrea
- Benato Lisa
- Bencze Gyorgy
- Bendavid Joshua
- Benecke Anna
- Benelli Gabriele
- Beni Noemi
- Benitez Jose F
- Benussi Luigi
- Beretvas Andrew
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- Berger Pirmin
- Berger Thomas
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- Bhandari Rohan
- Bhardwaj Ashutosh
- Bhardwaj Rishika
- Bharti Monika
- Bhat Muzamil Ahmad
- Bhat Pushpalatha C
- Bhatnagar Vipin
- Bhattacharya Rajarshi
- Bhattacharya Saptaparna
- Bhattacharya Satyaki
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- Bhawandeep Bhawandeep
- Bheesette Srinidhi
- Bhowmik Debabrata
- Bhowmik Sandeep
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- Bi Ran
- Bialkowska Helena
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- Brainerd Christopher
- Brandt Stephanie
- Branson James G
- Bravo Cameron
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- Brew Christopher
- Brigljevic Vuko
- Brinkerhoff Andrew
- Brivio Francesco
- Brochero Cifuentes Javier Andres
- Brom Jean-Marie
- Brondolin Erica
- Brooke James John
- Brown Robert M
- Bruno Giacomo
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- Butler Philip H
- Butz Erik
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- Chwalek Thorsten
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- Yu Shin-Shan
- Yuan Li
- Yumiceva Francisco
- Yusli Mohd Nizam
- Zabi Alexandre
- Zahid Sema
- Zaleski Shawn
- Zalewski Piotr
- Zanetti Anna
- Zanetti Marco
- Zarubin Anatoli
- Zarucki Mateusz
- Zecchinelli Angelo Giacomo
- Zenaiev Oleksandr
- Zenz Seth Conrad
- Zeuner Wolfram Dietrich
- Zevi Della Porta Giovanni
- Zghiche Amina
- Zhang Aobo
- Zhang Fengwangdong
- Zhang Huaqiao
- Zhang Jingyu
- Zhang Sijing
- Zhang Wenyu
- Zhang Yi
- Zhang Zhicai
- Zhao Jingzhou
- Zhokin Alexander
- Zhu De Hua
- Zhu Ren-Yuan
- Zientek Margaret
- Zlebcik Radek
- Zobec Joze
- Zoi Irene
- Zolkapli Zukhaimira
- Zorbakir Ibrahim Soner
- Zorbilmez Caglar
- Zotto Pierluigi
- Zou David
- Zucchetta Alberto
- Zumerle Gianni
- Zuo Xunwu
- Zuolo Davide
- Álvarez Fernández Adrian
- Özçelik Özlem
- Publication venue
- Publication date
- 01/01/2019
- Field of study
Abstract The parton-level top quark (t) forward-backward asymmetry and the anomalous chromoelectric (d̂ t) and chromomagnetic (μ̂ t) moments have been measured using LHC pp collisions at a center-of-mass energy of 13 TeV, collected in the CMS detector in a data sample corresponding to an integrated luminosity of 35.9 fb−1. The linearized variable AFB(1) is used to approximate the asymmetry. Candidate t t ¯ events decaying to a muon or electron and jets in final states with low and high Lorentz boosts are selected and reconstructed using a fit of the kinematic distributions of the decay products to those expected for t t ¯ final states. The values found for the parameters are AFB(1)=0.048−0.087+0.095(stat)−0.029+0.020(syst),μ̂t=−0.024−0.009+0.013(stat)−0.011+0.016(syst), and a limit is placed on the magnitude of | d̂ t| < 0.03 at 95% confidence level. [Figure not available: see fulltext.
Search for the pair production of light top squarks in the e(+/-)mu(-/+) final state in proton-proton collisions at root s=13 TeV
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- Zhukov V
- Zientek M
- Zito G
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- Zorbilmez C
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- Zou D
- Zucchetta A
- Zumerle G
- Zuolo D
- Publication venue
- Publication date
- 01/01/2019
- Field of study
A search for the production of a pair of top squarks at the LHC is presented. This search targets a region of parameter space where the kinematics of top squark pair production and top quark pair production are very similar, because of the mass difference between the top squark and the neutralino being close to the top quark mass. The search is performed with 35.9 fb(-1) of proton-proton collisions at a centre-of-mass energy of root s = 13 TeV, collected by the CMS detector in 2016, using events containing one electron-muon pair with opposite charge. The search is based on a precise estimate of the top quark pair background, and the use of the M-T2 variable, which combines the transverse mass of each lepton and the missing transverse momentum. No excess of events is found over the standard model predictions. Exclusion limits are placed at 95% confidence level on the production of top squarks up to masses of 208 GeV for models with a mass difference between the top squark and the lightest neutralino close to that of the top quark.Peer reviewe
Measurement of t(t)over-bar normalised multi-differential cross sections in pp collisions at root s=13 TeV, and simultaneous determination of the strong coupling strength, top quark pole mass, and parton distribution functions
- Author
- Aarrestad Thea Klaeboe
- Abbaneo Duccio
- Abbiendi Giovanni
- Abbrescia Marcello
- Abdalla Hassan
- Abdullin Salavat
- Abercrombie Daniel
- Acharya Himal
- Acosta Darin
- Acosta John Gabriel
- Adam Wolfgang
- Adams Mark Raymond
- Adams Todd
- Adzic Petar
- Afanasiev Serguei
- Agapitos Antonis
- Aggleton Robin
- Agram Jean-Laurent
- Ahmad Ashfaq
- Ahmad Muhammad
- Ahmad Muhammad
- Ahuja Sudha
- Akbiyik Melike
- Akchurin Nural
- Akgun Bora
- Al-bataineh Ayman
- Albajar Carmen
- Albergo Sebastiano
- Albert Andreas
- Albrow Michael
- Alcaraz Maestre Juan
- Aldaya Martin Maria
- Aleksandrov Aleksandar
- Alexander James
- Alhusseini Mohammad
- Alimena Juliette
- Allen Brandon
- Almond John
- Alverson George
- Alves Fábio Lúcio
- Alves Gilvan
- Alyari Maral
- Amapane Nicola
- Ambrogi Federico
- Amendola Chiara
- Amin Nick
- Amsler Claude
- Anagnostou Georgios
- Anderson Dustin
- Andrea Jeremy
- Andreev Vladimir
- Andreev Yuri
- Andrews Michael Benjamin
- Androsov Konstantin
- Antonelli Louis
- Antunovic Zeljko
- Apanasevich Leonard
- Apollinari Giorgio
- Apresyan Artur
- Apyan Aram
- Araujo Mariana
- Arcaro Daniel
- Arcidiacono Roberta
- Arenton Michael Wayne
- Argiro Stefano
- Arndt Till
- Arneodo Michele
- Asavapibhop Burin
- Asawatangtrakuldee Chayanit
- Asghar Muhammad Irfan
- Asilar Ece
- Askew Andrew
- Atakisi Ismail Okan
- Ather Mohsan Waseem
- Attikis Alexandros
- Auffray Etiennette
- Aushev Tagir
- Autermann Christian
- Auzinger Georg
- Avdeeva Ekaterina
- Avery Paul
- Avila Carlos
- Ayala Edy
- Azarkin Maksim
- Azhgirey Igor
- Aziz Tariq
- Azzi Patrizia
- Azzolini Virginia
- Azzurri Paolo
- Baarmand Marc M
- Babaev Anton
- Babounikau Illia
- Bacchetta Nicola
- Bachiller Irene
- Bachtis Michail
- Backhaus Malte
- Baden Drew
- Bagliesi Giuseppe
- Bahinipati Seema
- Baidali Sergei
- Baillon Paul
- Bainbridge Robert
- Bakas Georgios
- Bakhshiansohi Hamed
- Ball Austin
- Ball Fionn
- Ban Yong
- Band Reyer
- Banerjee Sudeshna
- Banerjee Sunanda
- Bansal Sunil
- Barbagli Giuseppe
- Barberis Emanuela
- Bargassa Pedrame
- Baringer Philip
- Barker Anthony
- Barnes Virgil E
- Barney David
- Barnyakov Alexander
- Baron Owen
- Barone Luciano
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- Barrio Luna Mar
- Bartek Rachel
- Barth Christian
- Bartosik Nazar
- Bartók Márton
- Baselga Marta
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- Bean Alice
- Beauceron Stephanie
- Beaudette Florian
- Beernaert Kelly
- Beghin Diego
- Behera Prafulla Kumar
- Behnke Olaf
- Behrens Ulf
- Bein Samuel
- Beirão Da Cruz E Silva Cristóvão
- Belchior Batista Das Chagas Ewerton
- Belforte Stefano
- Bell Ken W
- Bellan Riccardo
- Belloni Alberto
- Belyaev Alexander
- Belyaev Andrey
- Benaglia Andrea
- Benato Lisa
- Bencze Gyorgy
- Bendavid Joshua
- Benecke Anna
- Benelli Gabriele
- Beni Noemi
- Benitez Jose F
- Benussi Luigi
- Benvenuti Alberto
- Beretvas Andrew
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- Bhardwaj Rishika
- Bharti Monika
- Bhat Muzamil Ahmad
- Bhat Pushpalatha C
- Bhatnagar Vipin
- Bhattacharya Rajarshi
- Bhattacharya Saptaparna
- Bhattacharya Satyaki
- Bhattacharya Soham
- Bhawandeep Bhawandeep
- Bheesette Srinidhi
- Bhopatkar Vallary
- Bhowmik Debabrata
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- Bi Ran
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- Bornheim Adolf
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- Brainerd Christopher
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- Bravo Cameron
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- Brivio Francesco
- Brochero Cifuentes Javier Andres
- Brom Jean-Marie
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- Chapon Emilien
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- Chatterjee Rajdeep Mohan
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- Chauhan Shubhanshu
- Chauhan Sushil
- Chaves Jorge
- Chawla Ridhi
- Chazin Quero Barbara
- Checchia Paolo
- Chekhovsky Vladimir
- Chen Geng
- Chen Guo-Ming
- Chen He-Sheng
- Chen Kai-Feng
- Chen Mingshui
- Chen Po-Hsun
- Chen Xuan
- Chen Ye
- Chen Yi
- Chen Zhenyu
- Chenarani Shirin
- Cheng Tongguang
- Cheng Yangyang
- Cherepanov Vladimir
- Chernyavskaya Nadezda
- Chertok Maxwell
- Cheung Harry
- Chhibra Simranjit Singh
- Chiarito Brandon
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- Chinellato Jose
- Chistov Ruslan
- Chlebana Frank
- Cho Sungwoong
- Choi Suyong
- Choi Young-Il
- Chou John Paul
- Choudhary Brajesh C
- Choudhury Somnath
- Chu Jennifer
- Chudasama Ruchi
- Chwalek Thorsten
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- Yohay Rachel
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- Yuan Li
- Yumiceva Francisco
- Yusli Mohd Nizam
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- Zaganidis Nicolas
- Zahid Sema
- Zaleski Shawn
- Zalewski Piotr
- Zanetti Anna
- Zanetti Marco
- Zarubin Anatoli
- Zarucki Mateusz
- Zeinali Maryam
- Zenaiev Oleksandr
- Zenz Seth Conrad
- Zeuner Wolfram Dietrich
- Zevi Della Porta Giovanni
- Zeyrek Mehmet
- Zghiche Amina
- Zhang Aobo
- Zhang Fengwangdong
- Zhang Huaqiao
- Zhang Jingyu
- Zhang Sijing
- Zhang Zhicai
- Zhao Jingzhou
- Zhokin Alexander
- Zhu De Hua
- Zhu Ren-Yuan
- Zientek Margaret
- Zobec Joze
- Zoi Irene
- Zolkapli Zukhaimira
- Zorbakir Ibrahim Soner
- Zorbilmez Caglar
- Zotto Pierluigi
- Zou David
- Zucchetta Alberto
- Zumerle Gianni
- Zuo Xunwu
- Zuolo Davide
- Álvarez Fernández Adrian
- Özçelik Özlem
- Publication venue
- Publication date
- 01/01/2019
- Field of study
Peer reviewe
Search for strongly interacting massive particles generating trackless jets in proton-proton collisions at s = 13 TeV
- Author
- Aarrestad TK
- Aarup Petersen H
- Abbaneo D
- Abbiendi G
- Abbrescia M
- Abdullin S
- Abercrombie D
- Acharya H
- Acosta D
- Acosta JG
- Adam W
- Adams E
- Adams MR
- Adams T
- Adloff C
- Adzic P
- Agapitos A
- Agarwal G
- Aggleton R
- Agram J-L
- Aguilar-Benitez M
- Ahmad A
- Ahmad M
- Ahmed A
- Ahuja S
- Aime C
- Akchurin N
- Akgun B
- Akpinar A
- Albajar C
- Albergo S
- Albert A
- Albrow M
- Alcaraz Maestre J
- Aldaya Martin M
- Aldá Júnior WL
- Aleksandrov A
- Alexander J
- Alhusseini M
- Alimena J
- Alison J
- Allen B
- Almond J
- Alvarez Gonzalez B
- Alverson G
- Alves GA
- Aly R
- Alyari M
- Amapane N
- Amendola C
- Amin N
- Amram O
- Amsler C
- Anagnostou G
- Andrea J
- Andreev V
- Andreev Y
- Andrews MB
- Androsov K
- Antchev G
- Antunovic Z
- Apanasevich L
- Apollinari G
- Appelt E
- Apresyan A
- Apyan A
- Araujo M
- Arcaro D
- Arcidiacono R
- Arenton MW
- Argiro S
- Arneodo M
- Aruta C
- Asavapibhop B
- Asawatangtrakuldee C
- Asenov P
- Asghar MI
- Asilar E
- Askew A
- Asmuss P
- Aspell P
- Atakisi IO
- Atanassov I
- Ather MW
- Attikis A
- Auffray E
- Aushev T
- Auzinger G
- Avati V
- Avery P
- Avila C
- Awais A
- Awan MIM
- Ayala E
- Ayala G
- Aydogmus Sen F
- Azarkin M
- Azhgirey I
- Aziz T
- Azzi P
- Azzurri P
- Baarmand MM
- Babaev A
- Babounikau I
- Bacchetta N
- Bachiller I
- Bachtis M
- Backhaus M
- Baden A
- Baechler J
- Baginyan A
- Bagliesi G
- Bahinipati S
- Baillon P
- Bainbridge R
- Bakas G
- Bakhshiansohi H
- Bakirci MN
- Baldenegro Barrera C
- Ball AH
- Ban Y
- Band R
- Bandyopadhyay H
- Banerjee S
- Banerjee S
- Bansal S
- Barbagli G
- Barberis E
- Bargassa P
- Baringer P
- Barnes VE
- Barney D
- Baron O
- Barrio Luna M
- Bartek R
- Bartosik N
- Bartók M
- Bastos D
- Battilana C
- Baty A
- Bauer G
- Bauerdick LAT
- Baxter S
- Bayshev I
- Bean A
- Beauceron S
- Beaudette F
- Becerril Gonzalez H
- Bechtel J
- Bedoya CF
- Beghin D
- Behera PK
- Behera SC
- Behnke O
- Bein S
- Belchior Batista Das Chagas E
- Belforte S
- Bell KW
- Bellan R
- Belloni A
- Bellora A
- Belyaev A
- Belyaev A
- Benaglia A
- Benato L
- Bencze G
- Bendavid J
- Benecke A
- Benelli G
- Beni N
- Benitez JF
- Benussi L
- Berardi V
- Berenguer Antequera J
- Beretvas A
- Bergauer T
- Berger P
- Berger T
- Beri SB
- Bermúdez Martínez A
- Bernardes CA
- Bernet C
- Berretti M
- Berry D
- Berryhill J
- Bertacchi V
- Besancon M
- Beschi A
- Bhal E
- Bhardwaj A
- Bharti M
- Bhat MA
- Bhat PC
- Bhatnagar V
- Bhattacharya R
- Bhattacharya S
- Bhattacharya S
- Bhattacharya S
- Bheesette S
- Bhowmik D
- Bhowmik S
- Bhyun JH
- Bi R
- Bialkowska H
- Bianchini L
- Bianco M
- Bianco S
- Biasini M
- Biino C
- Bilei GM
- Bilin B
- Bin Anuar AA
- Bisello D
- Black K
- Blekman F
- Blinov V
- Bloch D
- Bloch P
- Bloom K
- Bluj M
- Blumenfeld B
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- Boletti A
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- Özçelik Ö
- Široký J
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2022
- Field of study
A search for dark matter in the form of strongly interacting massive particles (SIMPs) using the CMS detector at the LHC is presented. The SIMPs would be produced in pairs that manifest themselves as pairs of jets without tracks. The energy fraction of jets carried by charged particles is used as a key discriminator to suppress efficiently the large multijet background, and the remaining background is estimated directly from data. The search is performed using proton-proton collision data corresponding to an integrated luminosity of 16.1 fb - 1 , collected with the CMS detector in 2016. No significant excess of events is observed above the expected background. For the simplified dark matter model under consideration, SIMPs with masses up to 100 GeV are excluded and further sensitivity is explored towards higher masses
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