Global properties of Stochastic Loewner evolution driven by Levy processes

Standard Schramm-Loewner evolution (SLE) is driven by a continuous Brownian motion which then produces a trace, a continuous fractal curve connecting the singular points of the motion. If jumps are added to the driving function, the trace branches. In a recent publication [1] we introduced a generalized SLE driven by a superposition of a Brownian motion and a fractal set of jumps (technically a stable L\'evy process). We then discussed the small-scale properties of the resulting L\'evy-SLE growth process. Here we discuss the same model, but focus on the global scaling behavior which ensues as time goes to infinity. This limiting behavior is independent of the Brownian forcing and depends upon only a single parameter, $\alpha$, which defines the shape of the stable L\'evy distribution. We learn about this behavior by studying a Fokker-Planck equation which gives the probability distribution for endpoints of the trace as a function of time. As in the short-time case previously studied, we observe that the properties of this growth process change qualitatively and singularly at $\alpha =1$. We show both analytically and numerically that the growth continues indefinitely in the vertical direction for $\alpha > 1$, goes as $\log t$ for $\alpha = 1$, and saturates for $\alpha< 1$. The probability density has two different scales corresponding to directions along and perpendicular to the boundary. In the former case, the characteristic scale is $X(t) \sim t^{1/\alpha}$. In the latter case the scale is $Y(t) \sim A + B t^{1-1/\alpha}$ for $\alpha \neq 1$, and $Y(t) \sim \ln t$ for $\alpha = 1$. Scaling functions for the probability density are given for various limiting cases.Comment: Published versio

Nanoscale Confinement and Fluorescence Effects of Bacterial Light Harvesting Complex LH2 in Mesoporous Silicas

Many key chemical and biochemical reactions, particularly in living cells, take place in confined space at the mesoscopic scale. Toward understanding of physicochemical nature of biomacromolecules confined in nanoscale space, in this work we have elucidated fluorescence effects of a light harvesting complex LH2 in nanoscale chemical environments. Mesoporous silicas (SBA-15 family) with different shapes and pore sizes were synthesized and used to create nanoscale biomimetic environments for molecular confinement of LH2. A combination of UV-vis absorption, wide-field fluorescence microscopy, and in situ ellipsometry supports that the LH2 complexes are located inside the silica nanopores. Systematic fluorescence effects were observed and depend on degree of space confinement. In particular, the temperature dependence of the steady-state fluorescence spectra was analyzed in detail using condensed matter band shape theories. Systematic electronic-vibrational coupling differences in the LH2 transitions between the free and confined states are found, most likely responsible for the fluorescence effects experimentally observed

EurA1c: the European HbA1c Trial to Investigate the Performance of HbA1c Assays in 2166 Laboratories across 17 Countries and 24 Manufacturers by Use of the IFCC Model for Quality Targets

Background: A major objective of the IFCC Committee on Education and Use of Biomarkers in Diabetes is to generate awareness and improvement of HbA1c assays through evaluation of the performance by countries and manufacturers. Methods: Fresh whole blood and lyophilized hemolysate specimens manufactured from the same pool were used by 17 external quality assessment organizers to evaluate analytical performance of 2166 laboratories. Results were evaluated per country, per manufacturer, and per manufacturer and country combined according to criteria of the IFCC model for quality targets. Results: At the country level with fresh whole blood specimens, 6 countries met the IFCC criterion, 2 did not, and 2 were borderline. With lyophilized hemolysates, 5 countries met the criterion, 2 did not, and 3 were borderline. At the manufacturer level using fresh whole blood specimens, 13 manufacturers met the criterion, 8 did not, and 3 were borderline. Using lyophilized hemolysates, 7 manufacturers met the criterion, 6 did not, and 3 were borderline. In both country and manufacturer groups, the major contribution to total error derived from between-laboratory variation. There were no substantial differences in performance between groups using fresh whole blood or lyophilized hemolysate samples. Conclusions: The state of the art is that 1 of 20 laboratories does not meet the IFCC criterion, but there are substantial differences between country and between manufacturer groups. Efforts to further improve quality should focus on reducing between-laboratory variation. With some limitations, fresh whole blood and well-defined lyophilized specimens are suitable for purpose

Nuclear astrophysics with radioactive ions at FAIR

The nucleosynthesis of elements beyond iron is dominated by neutron captures in the s and r processes. However, 32 stable, proton-rich isotopes cannot be formed during those processes, because they are shielded from the s-process flow and r-process, β-decay chains. These nuclei are attributed to the p and rp process. For all those processes, current research in nuclear astrophysics addresses the need for more precise reaction data involving radioactive isotopes. Depending on the particular reaction, direct or inverse kinematics, forward or time-reversed direction are investigated to determine or at least to constrain the desired reaction cross sections. The Facility for Antiproton and Ion Research (FAIR) will offer unique, unprecedented opportunities to investigate many of the important reactions. The high yield of radioactive isotopes, even far away from the valley of stability, allows the investigation of isotopes involved in processes as exotic as the r or rp processes

The low-frequency environment of the Murchison Widefield Array : radio-frequency interference analysis and mitigation

This is the Accepted Manuscript version of the following article: A. R. Offringa, et al., “The low-frequency environment of the Murchison Widefield Array: radio-frequency interference analysis and mitigation”, Publications of the Astronomical Society of Australia, Vol. 32, March 2015. The final published version is available at: https://doi.org/10.1017/pasa.2015.7 © Astronomical Society of Australia 2015The Murchison Widefield Array (MWA) is a new low-frequency interferometric radio telescope built in Western Australia at one of the locations of the future Square Kilometre Array (SKA). We describe the automated radio-frequency interference (RFI) detection strategy implemented for the MWA, which is based on the AOFlagger platform, and present 72-231-MHz RFI statistics from 10 observing nights. RFI detection removes 1.1% of the data. RFI from digital TV (DTV) is observed 3% of the time due to occasional ionospheric or atmospheric propagation. After RFI detection and excision, almost all data can be calibrated and imaged without further RFI mitigation efforts, including observations within the FM and DTV bands. The results are compared to a previously published Low-Frequency Array (LOFAR) RFI survey. The remote location of the MWA results in a substantially cleaner RFI environment compared to LOFAR's radio environment, but adequate detection of RFI is still required before data can be analysed. We include specific recommendations designed to make the SKA more robust to RFI, including: the availability of sufficient computing power for RFI detection; accounting for RFI in the receiver design; a smooth band-pass response; and the capability of RFI detection at high time and frequency resolution (second and kHz-scale respectively).Peer reviewedFinal Accepted Versio

Interview investigation of insecure attachment styles as mediators between poor childhood care and schizophrenia-spectrum phenomenology

Background Insecure attachment styles have received theoretical attention and some initial empirical support as mediators between childhood adverse experiences and psychotic phenomena; however, further specificity needs investigating. The present interview study aimed to examine (i) whether two forms of poor childhood care, namely parental antipathy and role reversal, were associated with subclinical positive and negative symptoms and schizophrenia-spectrum personality disorder (PD) traits, and (ii) whether such associations were mediated by specific insecure attachment styles. Method A total of 214 nonclinical young adults were interviewed for subclinical symptoms (Comprehensive Assessment of At-Risk Mental States), schizophrenia-spectrum PDs (Structured Clinical Interview for DSM-IV Axis II Disorders), poor childhood care (Childhood Experience of Care and Abuse Interview), and attachment style (Attachment Style Interview). Participants also completed the Beck Depression Inventory-II and all the analyses were conducted partialling out the effects of depressive symptoms. Results Both parental antipathy and role reversal were associated with subclinical positive symptoms and with paranoid and schizotypal PD traits. Role reversal was also associated with subclinical negative symptoms. Angry-dismissive attachment mediated associations between antipathy and subclinical positive symptoms and both angry-dismissive and enmeshed attachment mediated associations of antipathy with paranoid and schizotypal PD traits. Enmeshed attachment mediated associations of role reversal with paranoid and schizotypal PD traits. Conclusions Attachment theory can inform lifespan models of how adverse developmental environments may increase the risk for psychosis. Insecure attachment provides a promising mechanism for understanding the development of schizophrenia-spectrum phenomenology and may offer a useful target for prophylactic intervention