196 research outputs found

    Peningkatan Aktivitas Dan Hasil Belajar Kognitif Siswa Melalui Penerapan Model Pembelajaran Think Talk Write (Ttw) Di Smuk

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    The study aims to improve activities and cognitive learning results trought the Think Talk Write. The study was in class X SMAK Warta Bhakti Kefamenanu with responden 35 people. Data collecting data through observation and tests students' cognitive learning outcomes. Data analysis using quantitative descriptive. Results of research on learning activities in the first cycle an average of 60%, and the second cycle reaches an average of 90%. Cognitive learning results in the first cycle an average of 72.53% and the second cycle average reached 94.59%. Based on these data concluded that an increase in activity and cognitive learning outcomes in each cycle through the implementation of learning model Think Talk Write.Tujuan penelitian ini untuk mengetahui peningkatan aktivitas dan hasil belajar siswa melalui penerapan model pembelajaran TTW. Penelitian dilakukan pada siswa kelas X SMAK Warta Bakti Kefamenanu dengan jumlah responden 35 orang. Pengumpulan data dilakukan melalui observasi dan tes hasil belajar kognitif siswa. Analisis data menggunakan deskriptif kuantitatif. Hasil penelitian pada aktivitas belajar pada siklus I rata-rata 60% dan siklus II mencapai rata-rata 90%. Hasil belajar kognitif pada siklus I rata-rata 72,53% dan siklus II rata-rata mencapai 94,59%. Berdasarkan data tersebut disimpulkan bahwa terjadi peningkatan aktivitas dan hasil belajar kognitif di setiap siklus melalui penerapan model pembelajaran Think Talk Write

    Preliminary trajectories in dietary behaviors during the COVID-19 pandemic: A public health call to action to face obesity

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    The world is currently struggling to face the coronavirus pandemic (COVID-19), and many countries have imposed lockdowns and recommended quarantine to limit both the spread of the virus and overwhelming demands for medical care. Direct implications include the disruption of work routines, boredom, depression, increased calorie consumption, and other similar harmful effects. The present narrative review article briefly analyzes the preliminary effects of the quarantine lifestyle from the standpoint of dietary habits. In six different databases, we searched for original articles up to 10 August 2020, assessing eating habits among populations during the COVID-19 pandemic, and recorded any change in the intake of major food categories, as well as changes in body weight. The research strategy yielded 364 articles, from which we selected 12 articles that fitted our goal. Our preliminary findings revealed a sharp rise of carbohydrates sources consumption, especially those with a high glycemic index (i.e., homemade pizza, bread, cake, and pastries), as well as more frequent snacks. A high consumption of fruits and vegetables, and protein sources, particularly pulses, was also recorded, although there was no clear peak of increase in the latter. Data concerning the consumption of junk foods lacked consistency, while there was a decreased alcohol intake and fresh fish/seafood consumption. As a possible connection, people gained body weight. Therefore, in the realistic perspective of a continuing global health emergency situation, timely preventive measures are needed to counteract obesity-related behaviors in the long-term, so as to prevent further health complications

    Morning and Afternoon Sampling and Herbage Chemical Composition of Rotationally Stocked Elephant Grass cv. Napier

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    Nutrient intake by grazing animals depends on the amount of dry matter consumed and its chemical composition. Forage grasses, as with any other plants, produce assimilates during the day via photosynthesis to sustain live tissues, plant growth and organic reserves (Taiz and Zeiger 2013). In that context, herbage chemical composition may vary according to variations in the photosynthesis-respiration balance throughout the day. From dawn to dusk the balance increases and herbage dry matter content as well as concentration of soluble carbohydrates increase, the reverse happening from dusk to dawn. That could interfere with nutritive value and nutrient intake of grazing animals (Delagarde 2000), since for a given bite volume the amount of herbage and its composition could vary depending on the time of the day. That could have implications for rotationally managed pastures, indicating a potential effect of time of changing animals from one paddock to the other as a management strategy. Against that background, the objective of this experiment was to evaluate dry matter (DM) content and the concentration of soluble carbohydrates (SC), crude protein (CP), neutral (NDF) and acid (ADF) detergent fibre in herbage samples harvested during the morning and afternoon periods from rotationally stocked elephant grass cv. Napier

    PARÂMETROS DE QUALIDADE DO PÃO FRANCÊS

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    Devido à ausência de metodologia para avaliação da qualidade do pão francês em Sistema de Alimentação Coletiva, o presente trabalho teve como objetivo avaliar os parâmetros físicos, físico-químicos e sensoriais do pão francês, comercializado em cinco panificadoras de Curitiba. Nas análises físicas, em cinco repetições, as amostras foram submetidas à determinação do peso, volume, volume específico, densidade e peso seco. As análises físicoquímicas foram realizadas em triplicata de acordo com procedimento da Association of Official Analytical Chemists (AOAC). Para avaliar a qualidade do pão foi utilizada a metodologia do sistema de pontuação global, mediante análise sensorial dos seguintes atributos: cor da crosta, forma e simetria, características da crosta, aspecto da pestana, aspecto de quebra da crosta, cor do miolo, porosidade, textura, aroma e sabor. Atribuiu-se pontuação (de 0 a 5) para cada variável, a qual foi multiplicada pelo fator que expressa a importância relativa de cada variável (totalizando 100 pontos), obtendo-se a classificação dos produtos pela soma dos pontos. Os resultados dos testes físicos e físicoquímicos das cinco amostras de pão francês apresentaram média de 52,23 g de peso, 31,98% de umidade, 68,02% de extrato seco, 35,49 g de peso seco, 371,8 cm3 de volume, 7,23 cm3/g de volume específico e 0,15 g/cm3 de densidade. As amostras XA, XB e XC apresentaram os melhores resultados podendo ser consideradas como as melhores. Na classificação pelo sistema de pontuação global, as amostras apresentaram diferença em nível de 1% de significância em relação à qualidade. As amostras XA e XB apresentaram boa qualidade, seguidas pelas amostras XC e XE (regular), sendo a amostra XD classificada como ruim. Os resultados obtidos permitem sugerir a adoção desta metodologia de avaliação para seleção de pão francês, em Sistema de Alimentação Coletiva. QUALITY PATTERNS OF FRENCH BREAD Abstract Due to the absence of a methodology to evaluate the quality of French bread in a Production of Collective Meals System, the present work had as objective to evaluate the quality, physical, physical-chemical and sensorial parameters of the French bread marketed in five bakeries in Curitiba (Brazil). In the physical analyses, with five repetitions, the samples were submitted to the determination of weight, volume, specific volume, density and dry weight. The physical-chemical analysis was accomplished with three replicates in agreement with the AOAC procedure. To evaluate the quality of the bread, the methodology of global punctuation system was used, by sensorial analysis of the following attributes: color of the crust, form and symmetry, characteristics of the crust, aspect of the lash, aspect of crust break, color of the crumb, porosity, texture, aroma and flavor. For each variable a grade (from 0 to 5) was attributed, which was multiplied by a factor that expressed the relative importance of each variable (to a total of 100 points), obtaining the product classification by the sum of the points. The results of the physical and physical-chemical tests of the five samples of French bread presented an average of 52,23 g of weight; 31,98% of humidity, 68,02% of dry extract, 35,49 g of dry weight, 371,8 cm3 of volume, 7,23 cm3/g of specific volume and 0,15 g/cm3 of density. The samples XA, XB and XC presented better results and could be considered as the best. In the classification using the global punctuation system, the samples presented difference at the level of 1% of significance in relation to the quality. The samples XA and XB presented good quality, followed by the samples XC and XE (regular), being the sample XD classified as bad. The results obtained allow suggest the evaluation methodology for selection of French bread in a Production of Collective Meals System

    Failure of cytokinesis and 2n gamete formation in Brazilian accessions of Paspalum.

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    Cytological analysis on 112 Brazilian accessions of Paspalum showed that 52 were affected by failure of first or second cytokinesis during microsporogenesis. When the failure of cytokinesis occurred only in the first division and in the second division the cytokinesis was normal, a dyad of microspores was formed. In most of them the two cells remained binucleate, but in some a restitutional nucleus was observed. When the first division was normal and the failure of cytokinesis occurred only in the second division, dyads and triads were observed. A restitutional nucleus in one or both cells of the dyad, or in the binucleate cell of the triad was also observed. The percentage of dyads and triads varied among accessions, reaching 15.75 of the sporads in some. The absence of cytokinesis indicates the possibility that the widespread occurrence of polyploidy in the genus Paspalum originates from 2n pollen grains

    Antimicrobial Nanoplexes meet Model Bacterial Membranes: the key role of Cardiolipin

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    Antimicrobial resistance to traditional antibiotics is a crucial challenge of medical research. Oligonucleotide therapeutics, such as antisense or Transcription Factor Decoys (TFDs), have the potential to circumvent current resistance mechanisms by acting on novel targets. However, their full translation into clinical application requires efficient delivery strategies and fundamental comprehension of their interaction with target bacterial cells. To address these points, we employed a novel cationic bolaamphiphile that binds TFDs with high affinity to form self-assembled complexes (nanoplexes). Confocal microscopy revealed that nanoplexes efficiently transfect bacterial cells, consistently with biological efficacy on animal models. To understand the factors affecting the delivery process, liposomes with varying compositions, taken as model synthetic bilayers, were challenged with nanoplexes and investigated with Scattering and Fluorescence techniques. Thanks to the combination of results on bacteria and synthetic membrane models we demonstrate for the first time that the prokaryotic-enriched anionic lipid Cardiolipin (CL) plays a key-role in the TFDs delivery to bacteria. Moreover, we can hypothesize an overall TFD delivery mechanism, where bacterial membrane reorganization with permeability increase and release of the TFD from the nanoplexes are the main factors. These results will be of great benefit to boost the development of oligonucleotides-based antimicrobials of superior efficacy

    Antimicrobial resistance among migrants in Europe: a systematic review and meta-analysis

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    BACKGROUND: Rates of antimicrobial resistance (AMR) are rising globally and there is concern that increased migration is contributing to the burden of antibiotic resistance in Europe. However, the effect of migration on the burden of AMR in Europe has not yet been comprehensively examined. Therefore, we did a systematic review and meta-analysis to identify and synthesise data for AMR carriage or infection in migrants to Europe to examine differences in patterns of AMR across migrant groups and in different settings. METHODS: For this systematic review and meta-analysis, we searched MEDLINE, Embase, PubMed, and Scopus with no language restrictions from Jan 1, 2000, to Jan 18, 2017, for primary data from observational studies reporting antibacterial resistance in common bacterial pathogens among migrants to 21 European Union-15 and European Economic Area countries. To be eligible for inclusion, studies had to report data on carriage or infection with laboratory-confirmed antibiotic-resistant organisms in migrant populations. We extracted data from eligible studies and assessed quality using piloted, standardised forms. We did not examine drug resistance in tuberculosis and excluded articles solely reporting on this parameter. We also excluded articles in which migrant status was determined by ethnicity, country of birth of participants' parents, or was not defined, and articles in which data were not disaggregated by migrant status. Outcomes were carriage of or infection with antibiotic-resistant organisms. We used random-effects models to calculate the pooled prevalence of each outcome. The study protocol is registered with PROSPERO, number CRD42016043681. FINDINGS: We identified 2274 articles, of which 23 observational studies reporting on antibiotic resistance in 2319 migrants were included. The pooled prevalence of any AMR carriage or AMR infection in migrants was 25·4% (95% CI 19·1-31·8; I2 =98%), including meticillin-resistant Staphylococcus aureus (7·8%, 4·8-10·7; I2 =92%) and antibiotic-resistant Gram-negative bacteria (27·2%, 17·6-36·8; I2 =94%). The pooled prevalence of any AMR carriage or infection was higher in refugees and asylum seekers (33·0%, 18·3-47·6; I2 =98%) than in other migrant groups (6·6%, 1·8-11·3; I2 =92%). The pooled prevalence of antibiotic-resistant organisms was slightly higher in high-migrant community settings (33·1%, 11·1-55·1; I2 =96%) than in migrants in hospitals (24·3%, 16·1-32·6; I2 =98%). We did not find evidence of high rates of transmission of AMR from migrant to host populations. INTERPRETATION: Migrants are exposed to conditions favouring the emergence of drug resistance during transit and in host countries in Europe. Increased antibiotic resistance among refugees and asylum seekers and in high-migrant community settings (such as refugee camps and detention facilities) highlights the need for improved living conditions, access to health care, and initiatives to facilitate detection of and appropriate high-quality treatment for antibiotic-resistant infections during transit and in host countries. Protocols for the prevention and control of infection and for antibiotic surveillance need to be integrated in all aspects of health care, which should be accessible for all migrant groups, and should target determinants of AMR before, during, and after migration. FUNDING: UK National Institute for Health Research Imperial Biomedical Research Centre, Imperial College Healthcare Charity, the Wellcome Trust, and UK National Institute for Health Research Health Protection Research Unit in Healthcare-associated Infections and Antimictobial Resistance at Imperial College London

    Business process management and supply chain collaboration: a critical comparison

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    The link between a firm and supply chain (SC) members has been recognised as one of the key issues for ensuring business success and achieving competitive advantage. Indeed, working across organisational boundaries is required to accomplish effective responses to customers’ needs. Our preliminary research confirmed that there are positive relationships between business process management (BPM), supply chain collaboration (SCC), collaborative advantage and organisational performance. This study is a step further and uses a multiple case design to illuminate the results and gain a greater understanding from extensive discussions about these relationships. By means of semi-structured interviews, the three main issues were identified as: (1) the link between BPM and organisational performance; (2) the link between BPM and SCC; and (3) the contextual factors and benefits achieved from working collaboratively with SC partners. The different scenarios of the link between BPM and SCC were developed in a taxonomy, and the case studies were used to illustrate the experience of intra- and inter-organisational practices in the developing economy of Thailand. The case studies’ results explain in depth that both BPM and SCC are important for improving organisational performance and competitiveness. BPM not only improves organisational performance directly, but also assists with collaborative activities that in turn help to improve internal capabilities. Additionally, the comparisons in issues relating to firm size, industry type, relationship closeness and relationship length were also included in this study

    Influence of single and binary doping of strontium and lithium on in vivo biological properties of bioactive glass scaffolds

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    Effects of strontium and lithium ion doping on the biological properties of bioactive glass (BAG) porous scaffolds have been checked in vitro and in vivo. BAG scaffolds were prepared by conventional glass melting route and subsequently, scaffolds were produced by evaporation of fugitive pore formers. After thorough physico-chemical and in vitro cell characterization, scaffolds were used for pre-clinical study. Soft and hard tissue formation in a rabbit femoral defect model after 2 and 4 months, were assessed using different tools. Histological observations showed excellent osseous tissue formation in Sr and Li + Sr scaffolds and moderate bone regeneration in Li scaffolds. Fluorochrome labeling studies showed wide regions of new bone formation in Sr and Li + Sr doped samples as compared to Li doped samples. SEM revealed abundant collagenous network and minimal or no interfacial gap between bone and implant in Sr and Li + Sr doped samples compared to Li doped samples. Micro CT of Li + Sr samples showed highest degree of peripheral cancellous tissue formation on periphery and cortical tissues inside implanted samples and vascularity among four compositions. Our findings suggest that addition of Sr and/or Li alters physico-chemical properties of BAG and promotes early stage in vivo osseointegration and bone remodeling that may offer new insight in bone tissue engineering
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