Serum hyaluronic acid and its association with liver stiffness in chronic hepatitis B patients

Background: Serum hyaluronic acid has an important role in the pathogenesis of liver fibrosis and is one of the most studied extracellular liver matrices. The purpose of this study was to examine the relationship between serum hyaluronic acid level and liver stiffness in hepatitis B chronic patients. Methods: This was an observational cross-sectional analytic study consisting of 43 samples of chronic hepatitis B patients. Serum hyaluronic acid was measured by the ELISA method. Liver stiffness describing fibrosis was examined using Fibro scan. Results: Among forty-three subject was predominantly by females (65.1%). The average age of the study subjects was 44.023 years old. The median serum hyaluronic acid level of the study subjects was 40.318 ng/mL. The median liver stiffness in the study subjects was 5.8 kPa. There was a significant positive correlation between serum hyaluronic acid levels and liver stiffness in the study subjects with a moderate strength of r = 0.448 (P = 0.003). Conclusion: Serum hyaluronic acid levels associated with liver stiffness

PEMBERDAYAAN MASYARAKAT DESA AIR GENTING DALAM PEMBUATAN PLANG NAMA JALAN

Plang nama jalan sangat berguna bagi masyarakat karena berisikan informasi tentang siatu lokasi/ nama jalan. Tidak adanya plang nama jalan di dusun IV, Desa Air Genting, Kecamata  Air Batu, Kabupaten Asahan, membuat masyarakat luar kesulitan untuk menemukan suatu lokasi diwilayah tersebut. Mahasiswa KKNT tahun 2022 berncana untuk menyelesaikan permasalahan tersebut dengan membuat plang nama jalan untuk dusun IV, Desa Air Genting, Kecamata  Air Batu, Kabupaten Asahan. Metode yang digunakan yaitu penyelesaian mitra secara langsung.pembuatan Plang nama jalan terdiri dari 6 unit, dengan ukuran 20 x 55 Cm dengan tinggi 165 Cm. dengan warna hijau dan tulisan berwarna putih, yang terdiri dari tiga bagian yaitu nama jalan, Dusun VI dan KKNT UNA 2022. Plang nama jalan kemudian dipasang dengan coran sedalam 20 Cm. pemasangan plang nama jalan ini sangat bermanfaat bagi masyarakat agar lebih mudah menemukan suatu lokasi. Kata Kunci : Plang, Nama Jala

Yang silam jadi suluh jadi suar : masjid warisan budaya di Jawa dan Madura

Buku ini dipersembahkan kepada khalayak sebagai pengingat kejayaan masa lalu. Pada masanya, para ulama pun bersatu padu bersama umat turut merintis kemerdekaan. Bahkan dalam perjalanannya kental dengan proses akulturasi budaya dan terjalinnya rasa toleransi antar agama yang tercermin nyata dari keagungan masjid-masjid lama yang masih kokoh berdiri di berbagai wilayah di Indonesia

Antimicrobial resistance among migrants in Europe: a systematic review and meta-analysis

BACKGROUND: Rates of antimicrobial resistance (AMR) are rising globally and there is concern that increased migration is contributing to the burden of antibiotic resistance in Europe. However, the effect of migration on the burden of AMR in Europe has not yet been comprehensively examined. Therefore, we did a systematic review and meta-analysis to identify and synthesise data for AMR carriage or infection in migrants to Europe to examine differences in patterns of AMR across migrant groups and in different settings. METHODS: For this systematic review and meta-analysis, we searched MEDLINE, Embase, PubMed, and Scopus with no language restrictions from Jan 1, 2000, to Jan 18, 2017, for primary data from observational studies reporting antibacterial resistance in common bacterial pathogens among migrants to 21 European Union-15 and European Economic Area countries. To be eligible for inclusion, studies had to report data on carriage or infection with laboratory-confirmed antibiotic-resistant organisms in migrant populations. We extracted data from eligible studies and assessed quality using piloted, standardised forms. We did not examine drug resistance in tuberculosis and excluded articles solely reporting on this parameter. We also excluded articles in which migrant status was determined by ethnicity, country of birth of participants' parents, or was not defined, and articles in which data were not disaggregated by migrant status. Outcomes were carriage of or infection with antibiotic-resistant organisms. We used random-effects models to calculate the pooled prevalence of each outcome. The study protocol is registered with PROSPERO, number CRD42016043681. FINDINGS: We identified 2274 articles, of which 23 observational studies reporting on antibiotic resistance in 2319 migrants were included. The pooled prevalence of any AMR carriage or AMR infection in migrants was 25·4% (95% CI 19·1-31·8; I2 =98%), including meticillin-resistant Staphylococcus aureus (7·8%, 4·8-10·7; I2 =92%) and antibiotic-resistant Gram-negative bacteria (27·2%, 17·6-36·8; I2 =94%). The pooled prevalence of any AMR carriage or infection was higher in refugees and asylum seekers (33·0%, 18·3-47·6; I2 =98%) than in other migrant groups (6·6%, 1·8-11·3; I2 =92%). The pooled prevalence of antibiotic-resistant organisms was slightly higher in high-migrant community settings (33·1%, 11·1-55·1; I2 =96%) than in migrants in hospitals (24·3%, 16·1-32·6; I2 =98%). We did not find evidence of high rates of transmission of AMR from migrant to host populations. INTERPRETATION: Migrants are exposed to conditions favouring the emergence of drug resistance during transit and in host countries in Europe. Increased antibiotic resistance among refugees and asylum seekers and in high-migrant community settings (such as refugee camps and detention facilities) highlights the need for improved living conditions, access to health care, and initiatives to facilitate detection of and appropriate high-quality treatment for antibiotic-resistant infections during transit and in host countries. Protocols for the prevention and control of infection and for antibiotic surveillance need to be integrated in all aspects of health care, which should be accessible for all migrant groups, and should target determinants of AMR before, during, and after migration. FUNDING: UK National Institute for Health Research Imperial Biomedical Research Centre, Imperial College Healthcare Charity, the Wellcome Trust, and UK National Institute for Health Research Health Protection Research Unit in Healthcare-associated Infections and Antimictobial Resistance at Imperial College London

Surgical site infection after gastrointestinal surgery in high-income, middle-income, and low-income countries: a prospective, international, multicentre cohort study

Background: Surgical site infection (SSI) is one of the most common infections associated with health care, but its importance as a global health priority is not fully understood. We quantified the burden of SSI after gastrointestinal surgery in countries in all parts of the world. Methods: This international, prospective, multicentre cohort study included consecutive patients undergoing elective or emergency gastrointestinal resection within 2-week time periods at any health-care facility in any country. Countries with participating centres were stratified into high-income, middle-income, and low-income groups according to the UN's Human Development Index (HDI). Data variables from the GlobalSurg 1 study and other studies that have been found to affect the likelihood of SSI were entered into risk adjustment models. The primary outcome measure was the 30-day SSI incidence (defined by US Centers for Disease Control and Prevention criteria for superficial and deep incisional SSI). Relationships with explanatory variables were examined using Bayesian multilevel logistic regression models. This trial is registered with ClinicalTrials.gov, number NCT02662231. Findings: Between Jan 4, 2016, and July 31, 2016, 13 265 records were submitted for analysis. 12 539 patients from 343 hospitals in 66 countries were included. 7339 (58·5%) patient were from high-HDI countries (193 hospitals in 30 countries), 3918 (31·2%) patients were from middle-HDI countries (82 hospitals in 18 countries), and 1282 (10·2%) patients were from low-HDI countries (68 hospitals in 18 countries). In total, 1538 (12·3%) patients had SSI within 30 days of surgery. The incidence of SSI varied between countries with high (691 [9·4%] of 7339 patients), middle (549 [14·0%] of 3918 patients), and low (298 [23·2%] of 1282) HDI (p < 0·001). The highest SSI incidence in each HDI group was after dirty surgery (102 [17·8%] of 574 patients in high-HDI countries; 74 [31·4%] of 236 patients in middle-HDI countries; 72 [39·8%] of 181 patients in low-HDI countries). Following risk factor adjustment, patients in low-HDI countries were at greatest risk of SSI (adjusted odds ratio 1·60, 95% credible interval 1·05–2·37; p=0·030). 132 (21·6%) of 610 patients with an SSI and a microbiology culture result had an infection that was resistant to the prophylactic antibiotic used. Resistant infections were detected in 49 (16·6%) of 295 patients in high-HDI countries, in 37 (19·8%) of 187 patients in middle-HDI countries, and in 46 (35·9%) of 128 patients in low-HDI countries (p < 0·001). Interpretation: Countries with a low HDI carry a disproportionately greater burden of SSI than countries with a middle or high HDI and might have higher rates of antibiotic resistance. In view of WHO recommendations on SSI prevention that highlight the absence of high-quality interventional research, urgent, pragmatic, randomised trials based in LMICs are needed to assess measures aiming to reduce this preventable complication

LKP : Rancang Bangun Aplikasi Penggajian Karyawanpada PT. Gagas Mandiri Surabaya

PT. Gagas Mandiri merupakan salah satu perusahaan yang bergerak di bidang konstruksi di Surabaya. Dalam menjalankan proses bisnisnya, PT. Gagas Mandiri memiliki berberapa divisi. Divisi personalia adalah salah satu divisi yang menangani permasalahan penggajian karyawan. Proses penggajian karyawan selama ini menggunakan proses manual dengan “Microsoft Office Excel”. Untuk meningkatkan efektif dan efisiensi proses perhitungan penggajian karyawan diterapkan aplikasi penggajian karyawan berbasis web. Aplikasi ini memiliki kecepatan proses pencatatan gaji pokok, perhitungan tunjangan, perhitungan lembur, serta perhitungan pinjaman, mencetak slip gaji, dan memberikan informasi setiap saat bagi pihak manajemen. Dengan mengimplementasikan aplikasi ini, dapat mengurangi waktu proses perhitungan gaji karyawan menjadi satu menit dibandingkan dua ribu delapan ratus delapan puluh menit. Implementasi aplikasi ini akan membantu Divisi Personalia bila ada kebijakan dari perusahaan

TA : Rancang Bangun Sistem Informasi Administrasi Akademik Berbasis Web pada SMA Ta’miriyah Surabaya

SMA Ta’miriyah Surabaya merupakan salah satu sekolah menengah atas swasta yang bercirikan islam beralamat di Jl. Indrapura No.2 Surabaya. Dalam penanganan informasi administrasi SMA Tamiriyah Surabaya mengenai data kehadiran, data nilai, data pembayaran SPP dan data pelanggaran, sangat sulit didapatkan oleh wali murid. Dikarenakan saat ini yang terjadi adalah pengolahan data yang masih internal menggunakan Microsoft office dan Microsoft excel, selain itu komunikasi antara wali murid dengan pihak sekolah hanya terjadi pada saat penerimaan rapot yang diadakan sekolah dua kali setiap semester. Akibatnya, wali murid kurang mendapatkan informasi mengenai perkembangan kegiatan putra-putrinya di sekolah. Solusi dari permasalahan di atas adalah dibuatnya suatu sistem informasi administrasi akademik berbasis web yang dapat mengatasi permasalahan mengenai proses pencatatan, penyimpanan, pemeliharaan, dan pencarian informasi administrasi pada SMA Ta’miriyah Surabaya. Sistem dibangun berbasis web karena pengguna dapat mengakses di mana saja melalui berbagai perangkat yang memiliki web browser. Metode yang digunakan untuk membangun sistem ini yaitu metode System Development Life Cycle (SDLC), yang memiliki 3 (tiga) tahapan antara lain: analisis sistem, desain sistem, dan implementasi sistem. Penelitian menghasilkan aplikasi sistem informasi administrasi akademik berbasis web. Aplikasi ini menghasilkan informasi kehadiran, informasi penilaian, informasi keuangan, dan informasi pelanggaran yang dapat digunakan oleh wali murid untuk memantau kegiatan putra-putrinya di sekolah terkait dengan informasi administrasi. Untuk pengembangan lebih lanjut dapat disarankan membuat sistem berbasis android serta ditambahkan proses rekap dan fasilitas unduh laporan informasi administrasi

LKP : Rancang Bangun Aplikasi Penggajian Karyawanpada PT. Gagas Mandiri Surabaya

PT. Gagas Mandiri merupakan salah satu perusahaan yang bergerak di bidang konstruksi di Surabaya. Dalam menjalankan proses bisnisnya, PT. Gagas Mandiri memiliki berberapa divisi. Divisi personalia adalah salah satu divisi yang menangani permasalahan penggajian karyawan. Proses penggajian karyawan selama ini menggunakan proses manual dengan “Microsoft Office Excel”. Untuk meningkatkan efektif dan efisiensi proses perhitungan penggajian karyawan diterapkan aplikasi penggajian karyawan berbasis web. Aplikasi ini memiliki kecepatan proses pencatatan gaji pokok, perhitungan tunjangan, perhitungan lembur, serta perhitungan pinjaman, mencetak slip gaji, dan memberikan informasi setiap saat bagi pihak manajemen. Dengan mengimplementasikan aplikasi ini, dapat mengurangi waktu proses perhitungan gaji karyawan menjadi satu menit dibandingkan dua ribu delapan ratus delapan puluh menit. Implementasi aplikasi ini akan membantu Divisi Personalia bila ada kebijakan dari perusahaan

Portable and Customizable Solar Panel Cleaner Design

The purpose of this research is to design a solar panel cleaning tool that is easy to operate and can adjust the size of the installed solar panels. There are several factors that can affect the performance of solar panels, namely the placement of solar panels that cause accumulation of dust, bird droppings and water (salt) stains. The traditional cleaning system is still done manually. Manual cleaning has several disadvantages such as panel damage, risk of worker accidents, movement difficulties, poor maintenance, and others. Therefore, a solar panel cleaning tool is needed on the market that can help optimize solar panel performance and is easy to operate. The method used in this research is to design a prototype solar panel cleaner that can be operated easily and can be adjusted according to the size of the installed solar panel. The result of this research is a prototype of a solar panel cleaning tool with a total mass of 6 kg and easy to operate with a microcontroller system. Effectively this equipment shows the function of the cleaning tool to do its job, namely cleaning dust. Furthermore, this research needs to analyze the techno-economics of addition batteries to facilitate operation

Serum hyaluronic acid and its association with liver stiffness in chronic hepatitis B patients

Background: Serum hyaluronic acid has an important role in the pathogenesis of liver fibrosis and is one of the most studied extracellular liver matrices. The purpose of this study was to examine the relationship between serum hyaluronic acid level and liver stiffness in hepatitis B chronic patients. Methods: This was an observational cross-sectional analytic study consisting of 43 samples of chronic hepatitis B patients. Serum hyaluronic acid was measured by the ELISA method. Liver stiffness describing fibrosis was examined using Fibro scan. Results: Among forty-three subject was predominantly by females (65.1%). The average age of the study subjects was 44.023 years old. The median serum hyaluronic acid level of the study subjects was 40.318 ng/mL. The median liver stiffness in the study subjects was 5.8 kPa. There was a significant positive correlation between serum hyaluronic acid levels and liver stiffness in the study subjects with a moderate strength of r = 0.448 (P = 0.003). Conclusion: Serum hyaluronic acid levels associated with liver stiffness