Vaping: Exploring perceptions and behaviors of students and ENDS products

Background: Electronic nicotine delivery systems (ENDS) have increased in use and media exposure with a 78% rise in usage between 2017 to 2018. While a gateway to addictive products, users are also unaware of the ingredients and their effects on the body. Interventions are limited. Further research is needed to investigate perceptions of ENDS and identify effective cessation strategies for young adults. Purpose: To explore the knowledge and attitudes of HS students regarding ENDS products and compare data collected over the year to determine effects of recent media exposure. Methods: Six focus groups (n = 45) were held in a rural high school. Students were asked four open ended questions which elicited dialogue regarding attitudes and behaviors about ENDS and suggestions for educational interventions. Results: Emerging themes were social and behavioral influences (peer pressure; nicotine addiction) ; knowledge deficit; media promotion or prevention. Suggested educational methods were explanation of the ingredients in ENDS, dramatic relief and visual depiction of the consequences. There was more focus in the media on prevention than last year. Conclusion/Implications: A knowledge deficit regarding the dangers of ENDS, including the damaging effects of nicotine, still exists. Data will lead to development of innovative interventions to decrease ENDS use in high schoolers.https://orb.binghamton.edu/research_days_posters_spring2020/1089/thumbnail.jp

Diagnosis of melanoma aspirates on ThinPrep®: The University of Michigan experience

The purpose of this study was to compare the cytologic features of melanoma fine-needle aspirates (FNAs) prepared by ThinPrep® (TP) with those in conventional smears (CS) and to identify any diagnostic pitfalls. Fifty-one aspirates diagnosed as melanoma were obtained, 36 of which were prepared by both TP and CS. The preparations were evaluated for cellularity, cell aggregates, cellular appearance, melanin pigment, cytoplasmic, and nuclear features. Categorical data were analyzed by the chi-square test and continuous data by the Wilcoxin-signed rank test. Correlation was determined by Spearman's test for bivariate correlations (rho). Good correlation between the two methods was identified for the following features: cellularity, cell type, bi/multinucleated cells, cytoplasmic features, NC ratio, and presence of macronucleoli. TP exhibits coarser chromatin compared to CS ( P = 0.005). Six of 36 CS contained large cellular groups; none of the TP contained them ( P = 0.018). Twenty-five of 36 CS contained intranuclear inclusions as opposed to 12/36 TP ( P < 0.001). The number of inclusions was significantly reduced on TP. The amount of intracellular melanin was the same with both techniques. Background melanin was markedly reduced on TP except when either trapped by fibrin or attached to cellular clusters ( P = 0.006). Background blood was also markedly reduced on TP ( P < 0.005). In summary, the cytological features of TP and CS for FNA evaluation of melanoma correlate well; however, one needs to be aware of the cytologic alterations introduced by TP. TP is a sufficient preparation method in the diagnosis of melanoma FNA aspirates when performed by clinicians. It is also a useful adjunct in bloody or low-cellular aspirates, where it tends to reduce the background blood and concentrate the cells. Diagn. Cytopathol. 2002;26:334–339. © 2002 Wiley-Liss, Inc.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/35310/1/10099_ftp.pd

Effort Mobilization when the Self is Involved: Some Lessons from the Cardiovascular System

In this article it is proposed that the principles of motivational intensity theory (Brehm & Self, 1989) apply to effort mobilization for challenges with consequences for performers' self-esteem and selfdefinition (i.e., self-involvement). Accordingly, involvement of the self makes success important and thus justifies the mobilization of high resources. However, up to this level of maximally justified resources, actual effort is mobilized in correspondence to subjective task difficulty as long as success is possible. We report a series of experimental studies that have operationalized effort intensity as cardiovascular reactivity during task performance and used multiple manipulations of self-involvement (social evaluation, self-awareness, ego involvement, personal goals) and task difficulty. The empirical evidence clearly supports the idea that the principles of motivational intensity theory apply to performance conditions that have direct consequences for self-definition and self-esteem and challenges a number of other theoretical accounts