The Hepatic Monocarboxylate Transporter 1 (MCT1) Contributes to the Regulation of Food Anticipation in Mice.

Daily recurring events can be predicted by animals based on their internal circadian timing system. However, independently from the suprachiasmatic nuclei (SCN), the central pacemaker of the circadian system in mammals, restriction of food access to a particular time of day elicits food anticipatory activity (FAA). This suggests an involvement of other central and/or peripheral clocks as well as metabolic signals in this behavior. One of the metabolic signals that is important for FAA under combined caloric and temporal food restriction is β-hydroxybutyrate (βOHB). Here we show that the monocarboxylate transporter 1 (Mct1), which transports ketone bodies such as βOHB across membranes of various cell types, is involved in FAA. In particular, we show that lack of the Mct1 gene in the liver, but not in neuronal or glial cells, reduces FAA in mice. This is associated with a reduction of βOHB levels in the blood. Our observations suggest an important role of ketone bodies and its transporter Mct1 in FAA under caloric and temporal food restriction

Meson-exchange currents and quasielastic neutrino cross sections in the SuperScaling Approximation model

We evaluate the quasielastic double differential neutrino cross sections obtained in a phenomenological model based on the superscaling behavior of electron scattering data. We compare our results with the recent experimental data for neutrinos of MiniBooNE and estimate the contribution of the vector meson-exchange currents in the 2p-2h sector.Comment: 6 pages, 4 figure

Scaling and isospin effects in quasielastic lepton-nucleus scattering in the Relativistic Mean Field Approach

The role of isospin in quasielastic electron scattering and charge-changing neutrino reactions is investigated in the relativistic impulse approximation. We analyze proton and neutron scaling functions making use of various theoretical descriptions for the final-state interactions, focusing on the effects introduced by the presence of strong scalar and vector terms in the relativistic mean field approach. An explanation for the differences observed in the scaling functions evaluated from $(e,e')$ and $(\nu,\mu)$ reactions is provided by invoking the differences in isoscalar and isovector contributions.Comment: 10 pages, 5 figures, submitted to Phys. Lett.

Superscaling predictions for neutrino-induced charged-current charged pion production at MiniBooNE

Superscaling approximation (SuSA) predictions to neutrino-induced charged-current charged pion production in the \Delta-resonance region are explored under MiniBooNE experimental conditions. The results obtained within SuSA for the flux-averaged double-differential cross sections of the \pi+ production for the \nu_\mu+CH_2 reaction as a function of the muon kinetic energy and of the scattering angle, the cross sections averaged over the angle, the total cross section for the \pi+ production, as well as CC1\pi+ to CCQE cross section ratio are compared with the corresponding MiniBooNE experimental data. The SuSA predictions are in good agreement with data on neutrino flux average cross-sections, but a somewhat different dependence on the neutrino energy is predicted than the one resulting from the experimental analysis.Comment: 15 pages, 6 figures, accepted for publication in Physics Letters

Is Area-Wide Pest Management Useful? The Case of Citrus Greening.

Citrus greening currently poses a severe threat to citrus production worldwide. No treatment or management strategy is yet available to cure the disease. Scientists recommend controlling the vector of the disease, and area-wide pest management has been proposed as a superior alternative to individual pest management. We analyzed a unique dataset of farm-level citrus yields that allowed us to test this hypothesis. We found that yields of blocks located in an area with higher participation in coordinated sprays were 28%, 73% and 98% percent higher in 2012/13, 2013/14, and 2014/15, respectively, compared to the yields of blocks under the same management but located in an area with lower participation; providing evidence on the efficiency of a well-performing pest management area to deal with HLB. However, participation in CHMAs has not been commensurate with this evidence. We present survey data that provide insights about producers’ preferences and attitudes toward the area-wide pest management program. Despite the economic benefit we found area-wide pest management can provide, the strategic uncertainty involved in relying on neighbors seems to impose too high of a cost for most growers, who end up not coordinating sprays

Measurement of the polarisation of W bosons produced with large transverse momentum in pp collisions at sqrt(s) = 7 TeV with the ATLAS experiment

This paper describes an analysis of the angular distribution of W->enu and W->munu decays, using data from pp collisions at sqrt(s) = 7 TeV recorded with the ATLAS detector at the LHC in 2010, corresponding to an integrated luminosity of about 35 pb^-1. Using the decay lepton transverse momentum and the missing transverse energy, the W decay angular distribution projected onto the transverse plane is obtained and analysed in terms of helicity fractions f0, fL and fR over two ranges of W transverse momentum (ptw): 35 < ptw < 50 GeV and ptw > 50 GeV. Good agreement is found with theoretical predictions. For ptw > 50 GeV, the values of f0 and fL-fR, averaged over charge and lepton flavour, are measured to be : f0 = 0.127 +/- 0.030 +/- 0.108 and fL-fR = 0.252 +/- 0.017 +/- 0.030, where the first uncertainties are statistical, and the second include all systematic effects.Comment: 19 pages plus author list (34 pages total), 9 figures, 11 tables, revised author list, matches European Journal of Physics C versio

Observation of a new chi_b state in radiative transitions to Upsilon(1S) and Upsilon(2S) at ATLAS

The chi_b(nP) quarkonium states are produced in proton-proton collisions at the Large Hadron Collider (LHC) at sqrt(s) = 7 TeV and recorded by the ATLAS detector. Using a data sample corresponding to an integrated luminosity of 4.4 fb^-1, these states are reconstructed through their radiative decays to Upsilon(1S,2S) with Upsilon->mu+mu-. In addition to the mass peaks corresponding to the decay modes chi_b(1P,2P)->Upsilon(1S)gamma, a new structure centered at a mass of 10.530+/-0.005 (stat.)+/-0.009 (syst.) GeV is also observed, in both the Upsilon(1S)gamma and Upsilon(2S)gamma decay modes. This is interpreted as the chi_b(3P) system.Comment: 5 pages plus author list (18 pages total), 2 figures, 1 table, corrected author list, matches final version in Physical Review Letter

Search for displaced vertices arising from decays of new heavy particles in 7 TeV pp collisions at ATLAS

We present the results of a search for new, heavy particles that decay at a significant distance from their production point into a final state containing charged hadrons in association with a high-momentum muon. The search is conducted in a pp-collision data sample with a center-of-mass energy of 7 TeV and an integrated luminosity of 33 pb^-1 collected in 2010 by the ATLAS detector operating at the Large Hadron Collider. Production of such particles is expected in various scenarios of physics beyond the standard model. We observe no signal and place limits on the production cross-section of supersymmetric particles in an R-parity-violating scenario as a function of the neutralino lifetime. Limits are presented for different squark and neutralino masses, enabling extension of the limits to a variety of other models.Comment: 8 pages plus author list (20 pages total), 8 figures, 1 table, final version to appear in Physics Letters

Measurement of the inclusive isolated prompt photon cross-section in pp collisions at sqrt(s)= 7 TeV using 35 pb-1 of ATLAS data

A measurement of the differential cross-section for the inclusive production of isolated prompt photons in pp collisions at a center-of-mass energy sqrt(s) = 7 TeV is presented. The measurement covers the pseudorapidity ranges |eta|<1.37 and 1.52<=|eta|<2.37 in the transverse energy range 45<=E_T<400GeV. The results are based on an integrated luminosity of 35 pb-1, collected with the ATLAS detector at the LHC. The yields of the signal photons are measured using a data-driven technique, based on the observed distribution of the hadronic energy in a narrow cone around the photon candidate and the photon selection criteria. The results are compared with next-to-leading order perturbative QCD calculations and found to be in good agreement over four orders of magnitude in cross-section.Comment: 7 pages plus author list (18 pages total), 2 figures, 4 tables, final version published in Physics Letters