114 research outputs found

    The body as a text of pain: five stories of women who have experienced sexual violence in the city of Medellín

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    Este artículo integra el resultado de una investigación que tuvo como propósito indagar por las percepciones que tienen de su cuerpo cinco mujeres de la ciudad de Medellín que han vivido violencia sexual y han sido atendidas por el Centro de Recursos Integrales para la Familia –CERFAMI– en el período comprendido entre 2010-2016, explorando los cambios que se evidencian en la relación con el propio cuerpo antes y después del hecho violento. En el estudio se realizó un proceso dialógico desde la perspectiva feminista, donde se tuvo acceso a un conjunto de experiencias del dolor y del abuso sobre la corporalidad femenina que permitieron reflexionar sobre la condición encarnada de subjetividades violentadas. Por lo tanto, cada uno de los testimonios de las mujeres que participaron en esta investigación integra el tejido sensible y el compromiso político y ético de este artículo.This article integrates the result of an investigation that had as a purpose search the perceptions about the body, of five Medellin city women that had experienced sexual violence and were attended by the Center of Integral Resources for the Family - CERFAMI in the Period between 2010-2016, exploring the changes that are evidenced in the relationship with the body itself before and after the violent event. In the study, a dialogical process was carried out to have access to a series of experiences of pain and abuse on the feminine corporality that allowed to reflect on the incarnated condition of violated subjectivities. Therefore, each of the testimonies of women who participated in this research integrate the sensitive background and the political and ethical commitment of this article

    Induced cycles in triangle graphs

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    The triangle graph of a graph GG, denoted by T(G){\cal T}(G), is the graph whose vertices represent the triangles (K3K_3 subgraphs) of GG, and two vertices of T(G){\cal T}(G) are adjacent if and only if the corresponding triangles share an edge. In this paper, we characterize graphs whose triangle graph is a cycle and then extend the result to obtain a characterization of CnC_n-free triangle graphs. As a consequence, we give a forbidden subgraph characterization of graphs GG for which T(G){\cal T}(G) is a tree, a chordal graph, or a perfect graph. For the class of graphs whose triangle graph is perfect, we verify a conjecture of the third author concerning packing and covering of triangles.Comment: 27 page

    Chick Embryo Partial Ischemia Model: A New Approach to Study Ischemia Ex Vivo

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    Background: Ischemia is a pathophysiological condition due to blockade in blood supply to a specific tissue thus damaging the physiological activity of the tissue. Different in vivo models are presently available to study ischemia in heart and other tissues. However, no ex vivo ischemia model has been available to date for routine ischemia research and for faster screening of anti-ischemia drugs. In the present study, we took the opportunity to develop an ex vivo model of partial ischemia using the vascular bed of 4th day incubated chick embryo. Methodology/Principal Findings: Ischemia was created in chick embryo by ligating the right vitelline artery using sterile surgical suture. Hypoxia inducible factor- 1 alpha (HIF-1a), creatine phospho kinase-MB and reactive oxygen species in animal tissues and cells were measured to confirm ischemia in chick embryo. Additionally, ranolazine, N-acetyl cysteine and trimetazidine were administered as an anti-ischemic drug to validate the present model. Results from the present study depicted that blocking blood flow elevates HIF-1a, lipid peroxidation, peroxynitrite level in ischemic vessels while ranolazine administration partially attenuates ischemia driven HIF-1a expression. Endothelial cell incubated on ischemic blood vessels elucidated a higher level of HIF-1a expression with time while ranolazine treatment reduced HIF-1a in ischemic cells. Incubation of caprine heart strip on chick embryo ischemia model depicted an elevated creatine phospho kinase-MB activity under ischemic condition while histology of the treated heart sections evoked edema and disruption of myofibril structures. Conclusions/Significance: The present study concluded that chick embryo partial ischemia model can be used as a novel ex vivo model of ischemia. Therefore, the present model can be used parallel with the known in vivo ischemia models in understanding the mechanistic insight of ischemia development and in evaluating the activity of anti-ischemic drug.status: publishe

    Integrated Micro/Nanoengineered Functional Biomaterials for Cell Mechanics and Mechanobiology: A Materials Perspective

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    Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/106681/1/adma201304431.pd

    Effect of platelet-rich plasma on the early bone formation around Ca-P-coated and non-coated oral implants in cortical bone.

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    Contains fulltext : 70436.pdf (publisher's version ) (Closed access)OBJECTIVES: The purpose of the present study was to investigate the effect of local application of platelet-rich plasma (PRP) on the early healing of cortical bone around Ti implants with two different surface configurations. MATERIAL AND METHODS: Six goats were used in this study. PRP fractions were obtained from a venous blood sample of the goats and administered immediately before implant insertion. PRP was applied via gel preparation and installation of the gel into the implant site, or via dipping of the implants in PRP fraction before insertion. A total of 36 implants (18 non-coated and 18 Ca-P-coated) were placed into the tibial cortical bone. The animals were sacrificed at 6 weeks after implantation and implants with surrounding tissue were prepared for histological examination. Histomorphometrical variables like the percentage of implant surface with direct bone-implant contact and the percentage of new and old bone adjacent to the implant were evaluated. RESULTS: More interfacial bone-to-implant contact was observed for all the three groups of Ca-P-coated implants and the Ti/PRP liquid group. All groups revealed similar percentages of old and new bone adjacent to the implant. CONCLUSIONS: It was concluded that the additional use of PRP did not have any effect on the early cortical bone response to the Ca-P-coated implants, while PRP in a liquid form showed a tendency to increase bone apposition to roughened titanium implants
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