25 research outputs found

    MMBnet 2017 - Proceedings of the 9th GI/ITG Workshop „Leistungs-, Verlässlichkeits- und Zuverlässigkeitsbewertung von Kommunikationsnetzen und Verteilten Systemen“

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    Nowadays, mathematical methods of systems and network monitoring, modeling, simulation, and performance, dependability and reliability analysis constitute the foundation of quantitative evaluation methods with regard to software-defined next-generation networks and advanced cloud computing systems. Considering the application of the underlying methodologies in engineering practice, these sophisticated techniques provide the basis in many different areas. The GI/ITG Technical Committee “Measurement, Modelling and Evaluation of Computing Systems“ (MMB) and its members have investigated corresponding research topics and initiated a series of MMB conferences and workshops over the last decades. Its 9th GI/ITG Workshop MMBnet 2017 „Leistungs-, Verlässlichkeits- und Zuverlässigkeitsbewertung von Kommunikationsnetzen und Verteilten Systemen“ was held at Hamburg University of Technology (TUHH), Germany, on September 14, 2017. The proceedings of MMBnet 2017 summarize the contributions of one invited talk and four contributed papers of young researchers. They deal with current research issues in next-generation networks, IP-based real-time communication systems, and new application architectures and intend to stimulate the reader‘s future research in these vital areas of modern information society

    Antimicrobial resistance among migrants in Europe: a systematic review and meta-analysis

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    BACKGROUND: Rates of antimicrobial resistance (AMR) are rising globally and there is concern that increased migration is contributing to the burden of antibiotic resistance in Europe. However, the effect of migration on the burden of AMR in Europe has not yet been comprehensively examined. Therefore, we did a systematic review and meta-analysis to identify and synthesise data for AMR carriage or infection in migrants to Europe to examine differences in patterns of AMR across migrant groups and in different settings. METHODS: For this systematic review and meta-analysis, we searched MEDLINE, Embase, PubMed, and Scopus with no language restrictions from Jan 1, 2000, to Jan 18, 2017, for primary data from observational studies reporting antibacterial resistance in common bacterial pathogens among migrants to 21 European Union-15 and European Economic Area countries. To be eligible for inclusion, studies had to report data on carriage or infection with laboratory-confirmed antibiotic-resistant organisms in migrant populations. We extracted data from eligible studies and assessed quality using piloted, standardised forms. We did not examine drug resistance in tuberculosis and excluded articles solely reporting on this parameter. We also excluded articles in which migrant status was determined by ethnicity, country of birth of participants' parents, or was not defined, and articles in which data were not disaggregated by migrant status. Outcomes were carriage of or infection with antibiotic-resistant organisms. We used random-effects models to calculate the pooled prevalence of each outcome. The study protocol is registered with PROSPERO, number CRD42016043681. FINDINGS: We identified 2274 articles, of which 23 observational studies reporting on antibiotic resistance in 2319 migrants were included. The pooled prevalence of any AMR carriage or AMR infection in migrants was 25·4% (95% CI 19·1-31·8; I2 =98%), including meticillin-resistant Staphylococcus aureus (7·8%, 4·8-10·7; I2 =92%) and antibiotic-resistant Gram-negative bacteria (27·2%, 17·6-36·8; I2 =94%). The pooled prevalence of any AMR carriage or infection was higher in refugees and asylum seekers (33·0%, 18·3-47·6; I2 =98%) than in other migrant groups (6·6%, 1·8-11·3; I2 =92%). The pooled prevalence of antibiotic-resistant organisms was slightly higher in high-migrant community settings (33·1%, 11·1-55·1; I2 =96%) than in migrants in hospitals (24·3%, 16·1-32·6; I2 =98%). We did not find evidence of high rates of transmission of AMR from migrant to host populations. INTERPRETATION: Migrants are exposed to conditions favouring the emergence of drug resistance during transit and in host countries in Europe. Increased antibiotic resistance among refugees and asylum seekers and in high-migrant community settings (such as refugee camps and detention facilities) highlights the need for improved living conditions, access to health care, and initiatives to facilitate detection of and appropriate high-quality treatment for antibiotic-resistant infections during transit and in host countries. Protocols for the prevention and control of infection and for antibiotic surveillance need to be integrated in all aspects of health care, which should be accessible for all migrant groups, and should target determinants of AMR before, during, and after migration. FUNDING: UK National Institute for Health Research Imperial Biomedical Research Centre, Imperial College Healthcare Charity, the Wellcome Trust, and UK National Institute for Health Research Health Protection Research Unit in Healthcare-associated Infections and Antimictobial Resistance at Imperial College London

    Surgical site infection after gastrointestinal surgery in high-income, middle-income, and low-income countries: a prospective, international, multicentre cohort study

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    Background: Surgical site infection (SSI) is one of the most common infections associated with health care, but its importance as a global health priority is not fully understood. We quantified the burden of SSI after gastrointestinal surgery in countries in all parts of the world. Methods: This international, prospective, multicentre cohort study included consecutive patients undergoing elective or emergency gastrointestinal resection within 2-week time periods at any health-care facility in any country. Countries with participating centres were stratified into high-income, middle-income, and low-income groups according to the UN's Human Development Index (HDI). Data variables from the GlobalSurg 1 study and other studies that have been found to affect the likelihood of SSI were entered into risk adjustment models. The primary outcome measure was the 30-day SSI incidence (defined by US Centers for Disease Control and Prevention criteria for superficial and deep incisional SSI). Relationships with explanatory variables were examined using Bayesian multilevel logistic regression models. This trial is registered with ClinicalTrials.gov, number NCT02662231. Findings: Between Jan 4, 2016, and July 31, 2016, 13 265 records were submitted for analysis. 12 539 patients from 343 hospitals in 66 countries were included. 7339 (58·5%) patient were from high-HDI countries (193 hospitals in 30 countries), 3918 (31·2%) patients were from middle-HDI countries (82 hospitals in 18 countries), and 1282 (10·2%) patients were from low-HDI countries (68 hospitals in 18 countries). In total, 1538 (12·3%) patients had SSI within 30 days of surgery. The incidence of SSI varied between countries with high (691 [9·4%] of 7339 patients), middle (549 [14·0%] of 3918 patients), and low (298 [23·2%] of 1282) HDI (p < 0·001). The highest SSI incidence in each HDI group was after dirty surgery (102 [17·8%] of 574 patients in high-HDI countries; 74 [31·4%] of 236 patients in middle-HDI countries; 72 [39·8%] of 181 patients in low-HDI countries). Following risk factor adjustment, patients in low-HDI countries were at greatest risk of SSI (adjusted odds ratio 1·60, 95% credible interval 1·05–2·37; p=0·030). 132 (21·6%) of 610 patients with an SSI and a microbiology culture result had an infection that was resistant to the prophylactic antibiotic used. Resistant infections were detected in 49 (16·6%) of 295 patients in high-HDI countries, in 37 (19·8%) of 187 patients in middle-HDI countries, and in 46 (35·9%) of 128 patients in low-HDI countries (p < 0·001). Interpretation: Countries with a low HDI carry a disproportionately greater burden of SSI than countries with a middle or high HDI and might have higher rates of antibiotic resistance. In view of WHO recommendations on SSI prevention that highlight the absence of high-quality interventional research, urgent, pragmatic, randomised trials based in LMICs are needed to assess measures aiming to reduce this preventable complication

    Der River Ecosystem Service Index in der Modellregion "Donauauen zwischen Neu-Ulm und Donauwörth" - Berücksichtigung vielfältiger Ökosystemleistungen bei der Planung von Hochwasserschutzmaßnahmen

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    Geplante Hochwasserrückhalteräume an der Donau in Bayern bilden das Grundgerüst für Szenarien, in denen Öko-systemleistungen für einen Alternativenvergleich herangezogen wurden. Der Vergleich wurde mit Hilfe des River Eco-system Services Index RESI erstellt, der im Auenmagazin 16 vorgestellt wurde. Der RESI ergänzt die klassischen mo-netären Bewertungsverfahren wie etwa die Kosten-Nutzen-Analyse durch eine fünfstufig skalierte Bewertung von 27 Ökosystemleistungen, basierend auf einer quantitativen und räumlich expliziten Erfassung (Puschetal. 2019). Für das Fallbeispiel Donau zeigt er klar die Vor- und Nachteile verschiedener Planungszustände für unterschiedliche Sek-toren auf und ermöglicht so eine integrative Entscheidungsfindung

    Next-Generation Satellite Communication Networks

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    This paper gives an overview of our recent activities in the field of satellite communication networks, including an introduction to geostationary satellite systems and Low Earth Orbit megaconstellations. To mitigate the high latencies of geostationary satellite networks, TCP-splitting Performance Enhancing Proxies are deployed. However, these cannot be applied in the case of encrypted transport headers as it is the case for VPNs or QUIC. We summarize performance evaluation results from multiple measurement campaigns. In a recently concluded project, multipath communication was used to combine the advantages of very heterogeneous communication paths: low data rate, low latency (e.g., DSL light) and high data rate, high latency (e.g., geostationary satellite)

    Towards a 5G Satellite Communication Framework for V2X

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    In recent years, satellite communication has been expanding its field of application in the world of computer networks. This paper aims to provide an overview of how a typical scenario involving 5G Non-Terrestrial Networks (NTNs) for vehicle to everything (V2X) applications is characterized. In particular, a first implementation of a system that integrates them together will be described. Such a framework will later be used to evaluate the performance of applications such as Vehicle Monitoring (VM), Remote Driving (RD), Voice Over IP (VoIP), and others. Different configuration scenarios such as Low Earth Orbit and Geostationary Orbit will be considered

    Das Konzept der Ökosystemleistungen – eine Chance für Integratives Gewässermanagement

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    The planning and implementation of management measures to improve the status of freshwaters and the natural flood retention potential of rivers and floodplains (Water Framework Directive, Natura2000, Floods directive) are often challenging due to the various users and diverse legal frameworks involved. The decision-making process could benefit from the assessment and evaluation of ecosystem services (ES) though the complementary knowledge about the effects of management options. ES can be understood as the direct and indirect contributions of ecosystems to human well-being. Research is needed on how the ES concept could be applied in riverine landscapes. Hence, the RESI (River Ecosystem Service Index) project developed a concept and a method for the assessment and evaluation of ES in rivers and floodplains in inter- and transdisciplinary cooperation across both theory and practice. Based on literature and feedback from experts in water management, the project aimed at defining key conceptual terms (such as offered ES, used ES, and human input) and an ES classification that is adapted to the application on riverine landscapes. For the resulting list of provisioning, regulating and cultural ES, methods for the spatially explicit assessment and evaluation were developed, which are presented here by the example of the regulating ES flood regulation and the cultural ES unspecific interaction with the riverine landscape. The results and the reflection of the practical relevance of ES show that the ES concept is applicable for river and floodplain management, and at the same time, stakeholders are interested in using it. The application of the RESI in planning scenarios created a crosssectoral basis for communication and knowledge exchange among all stakeholders, which facilitates the development of integrative management options and thus enables solving conflicts of interest.Die Planung und die Umsetzung von Bewirtschaftungsmaßnahmen zur Verbesserung des Gewässerzustands und des natürlichen Hochwasserrückhalts an Flüssen und Auen gemäß EG-Wasserrahmenrichtlinie (EU-WRRL), Flora-Fauna-Rahmenrichtlinie (FFH-RL) und Hochwasser-Risiko-Management-Richtlinie (HWRM-RL) sind häufig schwierig. Gründe dafür sind verschiedene Nutzungsansprüche und diverse rechtliche Rahmensetzungen. Die entsprechenden Entscheidungsprozesse können von einer Erfassung und Bewertung von Ökosystemleistungen (ÖSL) profitieren, indem ergänzende Informationen zu den Auswirkungen der Bewirtschaftungsoptionen bereitgestellt werden. ÖSL werden hier verstanden als direkte und indirekte Beiträge von Ökosystemen zum menschlichen Wohlbefinden. Allerdings wurde das ÖSL-Konzeptes bisher kaum in Flussauenlandschaften angewendet. Im Projekt RESI (River Ecosystem Service Index) wurde daher in Zusammenarbeit zwischen Wissenschaft und Praxis ein Konzept und eine Methodik zur Erfassung und Bewertung von ÖSL in Flüssen und Auen entwickelt. Ziel dabei war es, vor dem Hintergrund der aktuellen Literatur und des Feedbacks von Experten im Gewässermanagement anwendbare konzeptionelle Kernbegriffe wie bereitgestellte ÖSL, genutzte ÖSL und menschliche Beiträge zur Nutzbarmachung zu definieren und eine auf Flusslandschaften angepasste Klassifikation von ÖSL zu erstellen. Für die resultierende Liste der versorgenden, regulierenden und kulturellen ÖSL wurden geeignete Methoden zur Erfassung und Bewertung entwickelt, die hier am Beispiel der regulativen ÖSL „Hochwasserregulation“ und kulturellen ÖSL „unspezifische Interaktion mit der Flusslandschaft“ dargestellt werden. Die Ergebnisse sowie die Reflektion der Praxisrelevanz von ÖSL zeigen, dass das Konzept für die Bewirtschaftung von Flüssen und Auen anwendbar ist und in der Praxis auf großes Interesse stößt. Die Anwendung des RESI für Planungsszenarien schafft eine sektorenübergreifende Kommunikations- und Informationsbasis, in die alle Akteure einbezogen werden können, was die Ableitung integrativer Bewirtschaftungsoptionen erleichtert und somit die Lösung von Interessenskonflikten unterstützt
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