Exciting surface plasmons with transformation media

The final publication is available at Springer via http://dx.doi.org/10.1007/s11468-012-9361-5We present a way of exciting surface plasmon polaritons along non-patterned metallic surfaces by means of a flat squeezing slab designed with transformation optics. The slab changes the dispersion relation of incident light, enabling evanescent coupling to propagating surface plasmons. Unlike prism couplers, the proposed device does not introduce reflections at its input interface. Moreover, its compact geometry is suitable for integration. A feasible dielectric implementation of the coupler is suggested. Finally, we show that the angular response of the device can be engineered by using a non-uniform compression factor. As an example, we design a coupler with a half-power angular bandwidth 2. 5 times higher than that of a conventional dielectric coupler. © 2012 Springer Science+Business Media, LLC.Financial support by Spanish Ministerio de Ciencia e Innovacion (contracts CSD2008-00066 and TEC2008-06871-C02, and FPU grant) is gratefully acknowledged.García Meca, C.; Ortuño Molinero, R.; Martí Sendra, J.; Martínez Abietar, AJ. (2012). Exciting surface plasmons with transformation media. Plasmonics. 7(4):701-707. https://doi.org/10.1007/s11468-012-9361-5S70170774Raether H (1988) Surface plasmons on smooth and rough surfaces and on gratings. Springer-Verlag, BerlinBarnes WL, Dereux A, Ebbesen TW (2003) Surface plasmon subwavelength optics. Nature 424:824–830Maier SA (2007) Plasmonics: fundamentals and applications. Springer, New YorkSchuller JA, Barnard ES, Cai W, Jun YC, White JS, Brongersma ML (2010) Plasmonics for extreme light concentration and manipulation. Nat Mater 9:193–204Brongersma ML, Shalaev VM (2010) The case for plasmonics. Science 328:440–441Liu Y, Zentgraf T, Bartal G, Zhang X (2010) Transformational plasmon optics. Nano Lett 10:1991–1997Huidobro PA, Nesterov ML, Martín-Moreno L, García-Vidal FJ (2010) Transformation optics for plasmonics. Nano Lett 10:1985–1990Kadic M, Guenneau S, Enoch S (2010) Transformational plasmonics: cloak, concentrator and rotator for SPPs. Opt Express 18:12027–12032Zhang J, Xiao S, Wubs M, Mortensen NA (2011) Surface plasmon wave adapter designed with transformation optics. ACS Nano 5:4359–4364Pendry JB, Schurig D, Smith DR (2006) Controlling electromagnetic fields. Science 312:1780–1782Leonhardt U (2006) Optical conformal mapping. Science 312:1777–1780Leonhardt U, Philbin TG (2006) General relativity in electrical engineering. New J Phys 8:247Sambles JR, Bradbery GW, Yang F (1991) Optical excitation of surface plasmons: an introduction. Contemp Phys 32:173–183Rahm M, Roberts DA, Pendry JB, Smith DR (2008) Transformation-optical design of adaptive beam bends and beam expanders. Opt Express 16:11555–11567Vasic B, Isic G, Gajic R, Hingerl K (2009) Coordinate transformation based design of confined metamaterial structures. Phys Rev B 79:85103Tichit P, Burokur SN, Lustrac A (2009) Waveguide taper engineering using coordinate transformation technology. Opt Express 18:767–772Zang X, Jiang C (2010) Manipulating the field distribution via optical transformation. Opt Express 18:10168–10176García-Meca C, Tung MM, Galán JV, Ortuño R, Rodríguez-Fortuño FJ, Martí J, Martínez A (2011) Squeezing and expanding light without reflections via transformation optics. Opt Express 19:3562–3575Li J, Han S, Zhang S, Bartal G, Zhang X (2009) Designing the Fourier space with transformation optics. Opt Lett 34:3128–3130Li J, Pendry JB (2008) Hiding under the carpet: a new strategy for cloaking. Phys Rev Lett 101:20390

Transient disruption of M1 during response planning impairs subsequent offline consolidation

Transcranial magnetic stimulation (TMS) was used to probe the involvement of the left primary motor cortex (M1) in the consolidation of a sequencing skill. In particular we asked: (1) if M1 is involved in consolidation of planning processes prior to response execution (2) whether movement preparation and movement execution can undergo consolidation independently and (3) whether sequence consolidation can occur in a stimulus specific manner. TMS was applied to left M1 while subjects prepared left hand sequential finger responses for three different movement sequences, presented in an interleaved fashion. Subjects also trained on three control sequences, where no TMS was applied. Disruption of subsequent consolidation was observed, but only for sequences where subjects had been exposed to TMS during training. Further, reduced consolidation was only observed for movement preparation, not movement execution. We conclude that left M1 is causally involved in the consolidation of effective response planning for left hand movements prior to response execution, and mediates consolidation in a sequence specific manner. These results provide important new insights into the role of M1 in sequential memory consolidation and sequence response planning

Seed Regeneration Potential of Canopy Gaps at Early Formation Stage in Temperate Secondary Forests, Northeast China

Promoting the seed regeneration potential of secondary forests undergoing gap disturbances is an important approach for achieving forest restoration and sustainable management. Seedling recruitment from seed banks strongly determines the seed regeneration potential, but the process is poorly understood in the gaps of secondary forests. The objectives of the present study were to evaluate the effects of gap size, seed availability, and environmental conditions on the seed regeneration potential in temperate secondary forests. It was found that gap formation could favor the invasion of more varieties of species in seed banks, but it also could speed up the turnover rate of seed banks leading to lower seed densities. Seeds of the dominant species, Fraxinus rhynchophylla, were transient in soil and there was a minor and discontinuous contribution of the seed bank to its seedling emergence. For Quercus mongolica, emerging seedling number was positively correlated with seed density in gaps (R = 0.32, P<0.01), especially in medium and small gaps (<500 m2). Furthermore, under canopies, there was a positive correlation between seedling number and seed density of Acer mono (R = 0.43, P<0.01). Gap formation could promote seedling emergence of two gap-dependent species (i.e., Q. mongolica and A. mono), but the contribution of seed banks to seedlings was below 10% after gap creation. Soil moisture and temperature were the restrictive factors controlling the seedling emergence from seeds in gaps and under canopies, respectively. Thus, the regeneration potential from seed banks is limited after gap formation

X-ray emission from the Sombrero galaxy: discrete sources

We present a study of discrete X-ray sources in and around the bulge-dominated, massive Sa galaxy, Sombrero (M104), based on new and archival Chandra observations with a total exposure of ~200 ks. With a detection limit of L_X = 1E37 erg/s and a field of view covering a galactocentric radius of ~30 kpc (11.5 arcminute), 383 sources are detected. Cross-correlation with Spitler et al.'s catalogue of Sombrero globular clusters (GCs) identified from HST/ACS observations reveals 41 X-rays sources in GCs, presumably low-mass X-ray binaries (LMXBs). We quantify the differential luminosity functions (LFs) for both the detected GC and field LMXBs, whose power-low indices (~1.1 for the GC-LF and ~1.6 for field-LF) are consistent with previous studies for elliptical galaxies. With precise sky positions of the GCs without a detected X-ray source, we further quantify, through a fluctuation analysis, the GC LF at fainter luminosities down to 1E35 erg/s. The derived index rules out a faint-end slope flatter than 1.1 at a 2 sigma significance, contrary to recent findings in several elliptical galaxies and the bulge of M31. On the other hand, the 2-6 keV unresolved emission places a tight constraint on the field LF, implying a flattened index of ~1.0 below 1E37 erg/s. We also detect 101 sources in the halo of Sombrero. The presence of these sources cannot be interpreted as galactic LMXBs whose spatial distribution empirically follows the starlight. Their number is also higher than the expected number of cosmic AGNs (52+/-11 [1 sigma]) whose surface density is constrained by deep X-ray surveys. We suggest that either the cosmic X-ray background is unusually high in the direction of Sombrero, or a distinct population of X-ray sources is present in the halo of Sombrero.Comment: 11 figures, 5 tables, ApJ in pres

Identification of methylated deoxyadenosines in vertebrates reveals diversity in DNA modifications.

Methylation of cytosine deoxynucleotides generates 5-methylcytosine (m(5)dC), a well-established epigenetic mark. However, in higher eukaryotes much less is known about modifications affecting other deoxynucleotides. Here, we report the detection of N(6)-methyldeoxyadenosine (m(6)dA) in vertebrate DNA, specifically in Xenopus laevis but also in other species including mouse and human. Our methylome analysis reveals that m(6)dA is widely distributed across the eukaryotic genome and is present in different cell types but is commonly depleted from gene exons. Thus, direct DNA modifications might be more widespread than previously thought.M.J.K. was supported by the Long-Term Human Frontiers Fellowship (LT000149/2010-L), the Medical Research Council grant (G1001690), and by the Isaac Newton Trust Fellowship (R G76588). The work was sponsored by the Biotechnology and Biological Sciences Research Council grant BB/M022994/1 (J.B.G. and M.J.K.). The Gurdon laboratory is funded by the grant 101050/Z/13/Z (J.B.G.) from the Wellcome Trust, and is supported by the Gurdon Institute core grants, namely by the Wellcome Trust Core Grant (092096/Z/10/Z) and by the Cancer Research UK Grant (C6946/A14492). C.R.B. and G.E.A. are funded by the Wellcome Trust Core Grant. We are grateful to D. Simpson and R. Jones-Green for preparing X. laevis eggs and oocytes, F. Miller for providing us with M. musculus tissue, T. Dyl for X. laevis eggs and D. rerio samples, and to Gurdon laboratory members for their critical comments. We thank U. Ruether for providing us with M. musculus kidney DNA (Entwicklungs- und Molekularbiologie der Tiere, Heinrich Heine Universitaet Duesseldorf, Germany). We also thank J. Ahringer, S. Jackson, A. Bannister and T. Kouzarides for critical input and advice, M. Sciacovelli and E. Gaude for suggestions.This is the author accepted manuscript. The final version is available from Nature Publishing Group via http://dx.doi.org/10.1038/nsmb.314

Performance of the CMS Cathode Strip Chambers with Cosmic Rays

The Cathode Strip Chambers (CSCs) constitute the primary muon tracking device in the CMS endcaps. Their performance has been evaluated using data taken during a cosmic ray run in fall 2008. Measured noise levels are low, with the number of noisy channels well below 1%. Coordinate resolution was measured for all types of chambers, and fall in the range 47 microns to 243 microns. The efficiencies for local charged track triggers, for hit and for segments reconstruction were measured, and are above 99%. The timing resolution per layer is approximately 5 ns

High temperature dielectric ceramics: a review of temperature-stable high-permittivity perovskites

Recent developments are reviewed in the search for dielectric ceramics which can operate at temperatures >200 °C, well above the limit of existing high volumetric efficiency capacitor materials. Compositional systems based on lead-free relaxor dielectrics with mixed cation site occupancy on the perovskite lattice are summarised, and properties compared. As a consequence of increased dielectric peak broadening and shifts to peak temperatures, properties can be engineered such that a plateau in relative permittivity–temperature response (εr–T) is obtained, giving a ±15 %, or better, consistency in εr over a wide temperature range. Materials with extended upper temperature limits of 300, 400 and indeed 500 °C are grouped in this article according to the parent component of the solid solution, for example BaTiO3 and Na0.5Bi0.5TiO3. Challenges are highlighted in achieving a lower working temperature of −55 °C, whilst also extending the upper temperature limit of stable εr to ≥300 °C, and achieving high-permittivity and low values of dielectric loss tangent, tan δ. Summary tables and diagrams are used to help compare values of εr, tan δ, and temperature ranges of stability for different material

RNA interference as a key to knockdown overexpressed cyclooxygenase-2 gene in tumour cells

Silencing those genes that are overexpressed in cancer and contribute to the survival and progression of tumour cells is the aim of several researches. Cyclooxygenase-2 (COX-2) is one of the most intensively studied genes since it is overexpressed in most tumours, mainly in colon cancer. The use of specific COX-2 inhibitors to treat colon cancer has generated great enthusiasm. Yet, the side effects of some inhibitors emerging during long-term treatment have caused much concern. Genes silencing by RNA interference (RNAi) has led to new directions in the field of experimental oncology. In this study, we detected sequences directed against COX-2 mRNA, that potently downregulate COX-2 gene expression and inhibit phorbol 12-myristate 13-acetate-induced angiogenesis in vitro in a specific, nontoxic manner. Moreover, we found that the insertion of a specific cassette carrying anti-COX-2 short hairpin RNA sequence into a viral vector (pSUPER.retro) greatly increased silencing potency in a colon cancer cell line (HT29) without activating any interferon response. Phenotypically, COX-2 deficient HT29 cells showed a significant impairment of their in vitro malignant behaviour. Thus, the retroviral approach enhancing COX-2 knockdown, mediated by RNAi, proved to be an useful tool to better understand the role of COX-2 in colon cancer. Furthermore, the higher infection efficiency we observed in tumour cells, if compared to normal endothelial cells, may disclose the possibility to specifically treat tumour cells without impairing endothelial COX-2 activity