Evaluation of a digital learning object (HistoPete©) at OSUCHS

Introduction: Digital learning objects (DLOs) are units of learning designed for electronic delivery, can be used almost anywhere, can stand alone or be part of a system, and can be used independently or collaboratively. HistoPete© grew out of a computer-based instruction format in 1989, composed of several modules that took the student through the microscopic anatomy of the human body. DLOs can be reviewed or rated according to content quality, learning goal alignment, feedback and adaptation, motivation, presentation design, interaction usability, accessibility, reusability, and standards compliance. MERLOT suggests that an evaluation model for DLOs should include content quality, usability, and effective potential.Hypotheses: HistoPete© provides an active learning strategy in the histology course, biomedical foundation course, and systems courses.Study Design: The method of investigation was quantitative.Methods: Mixed methods were used in study. Student course evaluations were available from years 1999-2012. Comments from classes 2007-2016 were subjected to qualitative analyses using coding and placing in categories.Results: Results were graphed on a Likert scale for "HistoPete was useful" and a coding of the students comments revealed nine categories of comments.Conclusion: Students in the old and new curriculum found that HistoPete was useful and that it was an effective learning tool. Students in the old curriculum thought that it was a good preparation for the lab meeting. Students wanted larger images with higher resolution

Assessment of empiric outpatient therapy and readmission rates from the emergency department for community acquired pneumonia

Background: Community acquired pneumonia (CAP) is a common reason for emergency department visits and is associated with high mortality and readmission rates. The Center for Medicare and Medicaid Services (CMS) aims to decrease readmission rates for pneumonia through their Hospital Readmissions Reduction Program (HRRP) that was initiated in 2012. One study investigated avoidable causes of CAP readmission and discovered that the highest percentage of avoidable causes of readmission was related to discharging patients with either missing or incorrect diagnosis or therapy (31.7%). Emergency department (ED) physicians are in a unique position to impact these factors, as they are often responsible for initial diagnosis and empiric therapy initiation. The purpose of this study is to identify adherence to guideline-recommended empiric therapy and utilize the data to develop targeted interventions to refine our current practices.Methods: This study was performed as a single-center, retrospective, observational chart review. The study period was July 1, 2021-June 30, 2022, and the study included ED patients with an ICD-10 diagnosis code for pneumonia. Patients were independently reviewed by two investigators, with a third available for final statistical decision if needed. Each patient was reviewed for inclusion and exclusion criteria, and appropriateness of empiric therapy was evaluated according to the 2019 CAP guidelines. Patients were also reviewed for readmission within 30 days.Results: Data collection and analysis is still ongoing for this project. There were 169 total patients with a diagnosis code for CAP discharged from the emergency department during the pre-specified timeframe. For preliminary results 39 charts have been completed. 29 charts met inclusion criteria. Of these, only 2 had received appropriate empiric therapy. There were 10 total readmissions, with 3 of them being due to worsening pneumonia. None of the patients readmitted for worsening pneumonia had received appropriate empiric therapy. Extended duration and incomplete regimens for patients with comorbidities were the most common reasons for inappropriate therapy. Based on preliminary data, only 6% of patients received appropriate empiric therapy for CAP. Readmission rate overall was 35%, and rate of readmission for worsening pneumonia was 10%.Conclusions: Based on preliminary data, overall prescribing habits from the emergency department are not adherent with the guidelines. There is insufficient data to draw conclusions about the effect of this on readmission. Targeted provider education will be developed based on the most common reasons for incorrect therapy, with the goal of improving guideline adherence

Project Report No. 43, Site Index Equations for Loblolly and Slash Pine Plantations in East Texas, Update: 1996

In this update, after combining the data from the two subplots comprising each ETPPRP plot, the number of age-height pairs available for this analysis is 1,520 loblolly and 658 slash. the It is anticipated that the equations in this :996 update may productivity of East Texas loblolly and slash pine plantations quantify in a more accurate and reliable manner than the four previous sets 0: equations

Mitochondrial Genome Sequences Effectively Reveal the Phylogeny of Hylobates Gibbons

BACKGROUND: Uniquely among hominoids, gibbons exist as multiple geographically contiguous taxa exhibiting distinctive behavioral, morphological, and karyotypic characteristics. However, our understanding of the evolutionary relationships of the various gibbons, especially among Hylobates species, is still limited because previous studies used limited taxon sampling or short mitochondrial DNA (mtDNA) sequences. Here we use mtDNA genome sequences to reconstruct gibbon phylogenetic relationships and reveal the pattern and timing of divergence events in gibbon evolutionary history. METHODOLOGY/PRINCIPAL FINDINGS: We sequenced the mitochondrial genomes of 51 individuals representing 11 species belonging to three genera (Hylobates, Nomascus and Symphalangus) using the high-throughput 454 sequencing system with the parallel tagged sequencing approach. Three phylogenetic analyses (maximum likelihood, Bayesian analysis and neighbor-joining) depicted the gibbon phylogenetic relationships congruently and with strong support values. Most notably, we recover a well-supported phylogeny of the Hylobates gibbons. The estimation of divergence times using Bayesian analysis with relaxed clock model suggests a much more rapid speciation process in Hylobates than in Nomascus. CONCLUSIONS/SIGNIFICANCE: Use of more than 15 kb sequences of the mitochondrial genome provided more informative and robust data than previous studies of short mitochondrial segments (e.g., control region or cytochrome b) as shown by the reliable reconstruction of divergence patterns among Hylobates gibbons. Moreover, molecular dating of the mitogenomic divergence times implied that biogeographic change during the last five million years may be a factor promoting the speciation of Sundaland animals, including Hylobates species

Differential cross section measurements for the production of a W boson in association with jets in proton–proton collisions at √s = 7 TeV

Measurements are reported of differential cross sections for the production of a W boson, which decays into a muon and a neutrino, in association with jets, as a function of several variables, including the transverse momenta (pT) and pseudorapidities of the four leading jets, the scalar sum of jet transverse momenta (HT), and the difference in azimuthal angle between the directions of each jet and the muon. The data sample of pp collisions at a centre-of-mass energy of 7 TeV was collected with the CMS detector at the LHC and corresponds to an integrated luminosity of 5.0 fb[superscript −1]. The measured cross sections are compared to predictions from Monte Carlo generators, MadGraph + pythia and sherpa, and to next-to-leading-order calculations from BlackHat + sherpa. The differential cross sections are found to be in agreement with the predictions, apart from the pT distributions of the leading jets at high pT values, the distributions of the HT at high-HT and low jet multiplicity, and the distribution of the difference in azimuthal angle between the leading jet and the muon at low values.United States. Dept. of EnergyNational Science Foundation (U.S.)Alfred P. Sloan Foundatio

Penilaian Kinerja Keuangan Koperasi di Kabupaten Pelalawan

This paper describe development and financial performance of cooperative in District Pelalawan among 2007 - 2008. Studies on primary and secondary cooperative in 12 sub-districts. Method in this stady use performance measuring of productivity, efficiency, growth, liquidity, and solvability of cooperative. Productivity of cooperative in Pelalawan was highly but efficiency still low. Profit and income were highly, even liquidity of cooperative very high, and solvability was good

Optimasi Portofolio Resiko Menggunakan Model Markowitz MVO Dikaitkan dengan Keterbatasan Manusia dalam Memprediksi Masa Depan dalam Perspektif Al-Qur`an

Risk portfolio on modern finance has become increasingly technical, requiring the use of sophisticated mathematical tools in both research and practice. Since companies cannot insure themselves completely against risk, as human incompetence in predicting the future precisely that written in Al-Quran surah Luqman verse 34, they have to manage it to yield an optimal portfolio. The objective here is to minimize the variance among all portfolios, or alternatively, to maximize expected return among all portfolios that has at least a certain expected return. Furthermore, this study focuses on optimizing risk portfolio so called Markowitz MVO (Mean-Variance Optimization). Some theoretical frameworks for analysis are arithmetic mean, geometric mean, variance, covariance, linear programming, and quadratic programming. Moreover, finding a minimum variance portfolio produces a convex quadratic programming, that is minimizing the objective function ðð¥with constraintsð ð 𥠥 ðandð´ð¥ = ð. The outcome of this research is the solution of optimal risk portofolio in some investments that could be finished smoothly using MATLAB R2007b software together with its graphic analysis

Juxtaposing BTE and ATE – on the role of the European insurance industry in funding civil litigation

One of the ways in which legal services are financed, and indeed shaped, is through private insurance arrangement. Two contrasting types of legal expenses insurance contracts (LEI) seem to dominate in Europe: before the event (BTE) and after the event (ATE) legal expenses insurance. Notwithstanding institutional differences between different legal systems, BTE and ATE insurance arrangements may be instrumental if government policy is geared towards strengthening a market-oriented system of financing access to justice for individuals and business. At the same time, emphasizing the role of a private industry as a keeper of the gates to justice raises issues of accountability and transparency, not readily reconcilable with demands of competition. Moreover, multiple actors (clients, lawyers, courts, insurers) are involved, causing behavioural dynamics which are not easily predicted or influenced. Against this background, this paper looks into BTE and ATE arrangements by analysing the particularities of BTE and ATE arrangements currently available in some European jurisdictions and by painting a picture of their respective markets and legal contexts. This allows for some reflection on the performance of BTE and ATE providers as both financiers and keepers. Two issues emerge from the analysis that are worthy of some further reflection. Firstly, there is the problematic long-term sustainability of some ATE products. Secondly, the challenges faced by policymakers that would like to nudge consumers into voluntarily taking out BTE LEI