856 research outputs found

    Generation and measurement of nonstationary random processes technical note no. 3

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    Generation and measurement of nonstationary stochastic processes related to Monte Carlo studies with analog compute

    Water content detection in aviation fuel by using PMMA based optical fiber grating

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    Water in aviation fuel is a destructive contaminant and can cause serious problems that compromise aircraft’s safe operation and reduce its efficiency and lifetime. Online monitoring of water content in aviation fuel would permit the control of water content before it builds up to dangerous level. Optical fibers made of PMMA have water affinity. In a PMMA based optical fiber Bragg grating (POFBG) its refractive index and volume vary with the water content. This feature is used to detect tiny water content in aviation fuel in this work. The sensing mechanism of POFBG is analyzed. POFBG wavelength is found to be the function of both temperature and equilibrium relative humidity (ERH). POFBG response to water content in fuel can be determined by the ERH. The sensor is experimented at different environmental conditions to identify its sensitivity. As a result, a general expression of POFBG response is achieved. Water content in Jet-A1 is measured by using POFBG sensor calibrated with both environmental chamber and coulometric titration. POFBG sensor is finally tested in a simulation fuel tank, demonstrating a better performance than coulometric titration. A sensitivity of POFBG wavelength change to water content of 33 pm/ppm is achieved at room temperature, indicating detectable water content of 0.03 ppm

    Category-specific effects in Welsh mutation

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    In this paper we investigate category-specific effects through the lens of Welsh mutation. Smith (2011) and Moreton et al. (2017) show that English distinguishes nouns and proper nouns in an experimental blending task. Here we show that Welsh distinguishes nouns, verbs, personal names, and place names in the mutation system. We demonstrate these effects experimentally in a translation task designed to elicit mutation intuitions and in several corpus studies. In addition, we show that these effects correlate with lexical frequency. Deeper statistical analysis and a review of the English data suggests that frequency is a more explanatory factor than part of speech in both languages. We therefore argue that these category-specific effects can be reduced to lexical frequency effects.Open access journalThis item from the UA Faculty Publications collection is made available by the University of Arizona with support from the University of Arizona Libraries. If you have questions, please contact us at [email protected]

    Neutralization in Aztec Phonology – the Case of Classical Nahuatl Nasals

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    This article investigates nasal assimilation in Classical Nahuatl. The distribution of nasal consonants is shown to be the result of coda neutralization. It is argued that generalizations made for root and word level are disproportionate and cannot be explained through the means of rule-based phonology. It is shown that the process responsible for nasal distribution can only be accounted for by introducing derivational levels in Optimality Theor

    The industrial meaning of "gradualism": the Labour party and industry, 1918-1931

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    In the period from 1918 until 1931, the British Labour party adhered to the precepts of "gradualism": incrementally and by degrees, the party would gain support and pass legislation in an inexorable progress toward the socialist millennium. For a while, it seemed that this strategy would carry all before it. Emerging from the First World War with a "socialist" commitment, it became the largest opposition party at the 1918 general election. In 1922 it became the clear opposition to the Conservatives, and Ramsay MacDonald was reelected leader after an eight-year break. A short-lived minority Labour government in 1924 was followed by heavy electoral defeat, but the party was able to form its second minority government in 1929. However, its credibility was destroyed by soaring unemployment, and the ministry collapsed in the summer of 1931 after failing to agree on public expenditure cuts. MacDonald and the chancellor of the Exchequer, Philip Snowden, led a small Labour cohort into a "National" government, which went on to crush Labour at the polls that October. Detailed work on this complex period of Labour's history is hard to find, however. Little work has been done on policy: in particular, it is surprising that, given the party's symbiotic link with trade unionism and the central role of industry in Labour leaders' conception of the transformation to socialism, so little attention has been paid to the party's industrial policy in this period

    The ethics of distress: Toward a framework for determining the ethical acceptability of distressing health promotion advertising

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    © 2014 International Union of Psychological Science. Distressing health promotion advertising involves the elicitation of negative emotion to increase the likelihood that health messages will stimulate audience members to adopt healthier behaviors. Irrespective of its effectiveness, distressing advertising risks harming audience members who do not consent to the intervention and are unable to withdraw from it. Further, the use of these approaches may increase the potential for unfairness or stigmatization toward those targeted, or be considered unacceptable by some sections of the public. We acknowledge and discuss these concerns, but, using the public health ethics literature as a guide, argue that distressing advertising can be ethically defensible if conditions of effectiveness, proportionality necessity, least infringement, and public accountability are satisfied. We do not take a broad view as to whether distressing advertising is ethical or unethical, because we see the evidence for both the effectiveness of distressing approaches and their potential to generate iatrogenic effects to be inconclusive. However, we believe it possible to use the current evidence base to make informed estimates of the likely consequences of specific message presentations. Messages can be pre-tested and monitored to identify and deal with potential problems. We discuss how advertisers can approach the problems of deciding on the appropriate intensity of ethical review, and evaluating prospective distressing advertising campaigns against the conditions outlined

    TIGIT Marks Exhausted T Cells, Correlates with Disease Progression, and Serves as a Target for Immune Restoration in HIV and SIV Infection.

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    HIV infection induces phenotypic and functional changes to CD8+ T cells defined by the coordinated upregulation of a series of negative checkpoint receptors that eventually result in T cell exhaustion and failure to control viral replication. We report that effector CD8+ T cells during HIV infection in blood and SIV infection in lymphoid tissue exhibit higher levels of the negative checkpoint receptor TIGIT. Increased frequencies of TIGIT+ and TIGIT+ PD-1+ CD8+ T cells correlated with parameters of HIV and SIV disease progression. TIGIT remained elevated despite viral suppression in those with either pharmacological antiretroviral control or immunologically in elite controllers. HIV and SIV-specific CD8+ T cells were dysfunctional and expressed high levels of TIGIT and PD-1. Ex-vivo single or combinational antibody blockade of TIGIT and/or PD-L1 restored viral-specific CD8+ T cell effector responses. The frequency of TIGIT+ CD4+ T cells correlated with the CD4+ T cell total HIV DNA. These findings identify TIGIT as a novel marker of dysfunctional HIV-specific T cells and suggest TIGIT along with other checkpoint receptors may be novel curative HIV targets to reverse T cell exhaustion
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