Genetic code on the dyadic plane

We introduce the simple parametrization for the space of codons (triples of nucleotides) by 8\times 8 table. This table (which we call the dyadic plane) possesses the natural 2-adic ultrametric. We show that after this parametrization the genetic code will be a locally constant map of the simple form. The local constancy of this map will describe degeneracy of the genetic code. The map of the genetic code defines 2-adic ultrametric on the space of amino acids. We show that hydrophobic amino acids will be clustered in two balls with respect to this ultrametric. Therefore the introduced parametrization of space of codons exhibits the hidden regularity of the genetic code.Comment: Some gap in the construction was fixe

Unusual physics of quantum plasmas

We discuss some of the peculiarities of collective phenomena in a quantum plasma. In particular, we consider “elementary” collective phenomena such as charge shielding, volume and surface oscillations in a degenerate quantum plasma, and discuss how they change compared to those in a classical plasma.Обсуждаются некоторые особенности коллективных эффектов в квантовой плазме. В частности, рассматриваются такие “элементарные” коллективные явления, как экранирование заряда, объемные и поверхностные колебания в вырожденной квантовой плазме, и обсуждаются их отличия от аналогичных явлений в классической плазме.Обговорюються деякi особливостi колективних ефектiв у квантовiй плазмi. Зокрема, розглядаються такi “елементарнi” колективнi явища, як екранування заряду, об’ємнi та поверхневi коливання в виродженiй квантовій плазмi, та обговорюються їх вiдмiнностi вiд аналогiчних явищ у класичнiй плазм

Replica symmetry breaking related to a general ultrametric space III: the case of general measure

Family of replica matrices, related to general ultrametric spaces with general measures, is introduced. These matrices generalize the known Parisi matrices. Some functionals of replica approach are computed. Replica symmetry breaking solution is found.Comment: 21 page

A p-Adic Model of DNA Sequence and Genetic Code

Using basic properties of p-adic numbers, we consider a simple new approach to describe main aspects of DNA sequence and genetic code. Central role in our investigation plays an ultrametric p-adic information space which basic elements are nucleotides, codons and genes. We show that a 5-adic model is appropriate for DNA sequence. This 5-adic model, combined with 2-adic distance, is also suitable for genetic code and for a more advanced employment in genomics. We find that genetic code degeneracy is related to the p-adic distance between codons.Comment: 13 pages, 2 table

Rotational kinetics of absorbing dust grains in neutral gas

We study the rotational and translational kinetics of massive particulates (dust grains) absorbing the ambient gas. Equations for microscopic phase densities are deduced resulting in the Fokker-Planck equation for the dust component. It is shown that although there is no stationary distribution, the translational and rotational temperatures of dust tend to certain values, which differ from the temperature of the ambient gas. The influence of the inner structure of grains on rotational kinetics is also discussed.Comment: REVTEX4, 20 pages, 2 figure

Long-range attraction between particles in dusty plasma and partial surface tension of dusty phase boundary

Effective potential of a charged dusty particle moving in homogeneous plasma has a negative part that provides attraction between similarly charged dusty particles. A depth of this potential well is great enough to ensure both stability of crystal structure of dusty plasma and sizable value of surface tension of a boundary surface of dusty region. The latter depends on the orientation of the surface relative to the counter-ion flow, namely, it is maximal and positive for the surface normal to the flow and minimal and negative for the surface along the flow. For the most cases of dusty plasma in a gas discharge, a value of the first of them is more than sufficient to ensure stability of lenticular dusty phase void oriented across the counter-ion flow.Comment: LATEX, REVTEX4, 7 pages, 6 figure

p-Adic Mathematical Physics

A brief review of some selected topics in p-adic mathematical physics is presented.Comment: 36 page

Magnetic fields in cosmic particle acceleration sources

We review here some magnetic phenomena in astrophysical particle accelerators associated with collisionless shocks in supernova remnants, radio galaxies and clusters of galaxies. A specific feature is that the accelerated particles can play an important role in magnetic field evolution in the objects. We discuss a number of CR-driven, magnetic field amplification processes that are likely to operate when diffusive shock acceleration (DSA) becomes efficient and nonlinear. The turbulent magnetic fields produced by these processes determine the maximum energies of accelerated particles and result in specific features in the observed photon radiation of the sources. Equally important, magnetic field amplification by the CR currents and pressure anisotropies may affect the shocked gas temperatures and compression, both in the shock precursor and in the downstream flow, if the shock is an efficient CR accelerator. Strong fluctuations of the magnetic field on scales above the radiation formation length in the shock vicinity result in intermittent structures observable in synchrotron emission images. Resonant and non-resonant CR streaming instabilities in the shock precursor can generate mesoscale magnetic fields with scale-sizes comparable to supernova remnants and even superbubbles. This opens the possibility that magnetic fields in the earliest galaxies were produced by the first generation Population III supernova remnants and by clustered supernovae in star forming regions.Comment: 30 pages, Space Science Review

Global, regional, and national age-sex-specific mortality and life expectancy, 1950–2017: a systematic analysis for the Global Burden of Disease Study 2017

BACKGROUND: Assessments of age-specific mortality and life expectancy have been done by the UN Population Division, Department of Economics and Social Affairs (UNPOP), the United States Census Bureau, WHO, and as part of previous iterations of the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD). Previous iterations of the GBD used population estimates from UNPOP, which were not derived in a way that was internally consistent with the estimates of the numbers of deaths in the GBD. The present iteration of the GBD, GBD 2017, improves on previous assessments and provides timely estimates of the mortality experience of populations globally. METHODS: The GBD uses all available data to produce estimates of mortality rates between 1950 and 2017 for 23 age groups, both sexes, and 918 locations, including 195 countries and territories and subnational locations for 16 countries. Data used include vital registration systems, sample registration systems, household surveys (complete birth histories, summary birth histories, sibling histories), censuses (summary birth histories, household deaths), and Demographic Surveillance Sites. In total, this analysis used 8259 data sources. Estimates of the probability of death between birth and the age of 5 years and between ages 15 and 60 years are generated and then input into a model life table system to produce complete life tables for all locations and years. Fatal discontinuities and mortality due to HIV/AIDS are analysed separately and then incorporated into the estimation. We analyse the relationship between age-specific mortality and development status using the Socio-demographic Index, a composite measure based on fertility under the age of 25 years, education, and income. There are four main methodological improvements in GBD 2017 compared with GBD 2016: 622 additional data sources have been incorporated; new estimates of population, generated by the GBD study, are used; statistical methods used in different components of the analysis have been further standardised and improved; and the analysis has been extended backwards in time by two decades to start in 1950. FINDINGS: Globally, 18·7% (95% uncertainty interval 18·4–19·0) of deaths were registered in 1950 and that proportion has been steadily increasing since, with 58·8% (58·2–59·3) of all deaths being registered in 2015. At the global level, between 1950 and 2017, life expectancy increased from 48·1 years (46·5–49·6) to 70·5 years (70·1–70·8) for men and from 52·9 years (51·7–54·0) to 75·6 years (75·3–75·9) for women. Despite this overall progress, there remains substantial variation in life expectancy at birth in 2017, which ranges from 49·1 years (46·5–51·7) for men in the Central African Republic to 87·6 years (86·9–88·1) among women in Singapore. The greatest progress across age groups was for children younger than 5 years; under-5 mortality dropped from 216·0 deaths (196·3–238·1) per 1000 livebirths in 1950 to 38·9 deaths (35·6–42·83) per 1000 livebirths in 2017, with huge reductions across countries. Nevertheless, there were still 5·4 million (5·2–5·6) deaths among children younger than 5 years in the world in 2017. Progress has been less pronounced and more variable for adults, especially for adult males, who had stagnant or increasing mortality rates in several countries. The gap between male and female life expectancy between 1950 and 2017, while relatively stable at the global level, shows distinctive patterns across super-regions and has consistently been the largest in central Europe, eastern Europe, and central Asia, and smallest in south Asia. Performance was also variable across countries and time in observed mortality rates compared with those expected on the basis of development. INTERPRETATION: This analysis of age-sex-specific mortality shows that there are remarkably complex patterns in population mortality across countries. The findings of this study highlight global successes, such as the large decline in under-5 mortality, which reflects significant local, national, and global commitment and investment over several decades. However, they also bring attention to mortality patterns that are a cause for concern, particularly among adult men and, to a lesser extent, women, whose mortality rates have stagnated in many countries over the time period of this study, and in some cases are increasing