207 research outputs found

    Effect of Study Circle on Moral Attitudes of Filipino College Students

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    The study sought to find out the effect of study circle on the moral values of Filipino psychology students of Samar State University, to identify probable external factors, and to develop an improved study circle material to use in this inquiry. The study is anchored on the interrelated theories of cognitive, affective and social potentials as a way to achieve moral and social learning set forth by Kohlberg, Fraenkel, Raths, and Durkheim that occurs spontaneously within the individual. Utilizing the method of triangulation composed of qualitative and quantitative approaches to research, the study examined the process of participation in religious scripture-based study material resulting in the transformation of the person’s moral attitude. The findings revealed that participants in the study circle developed better moral attitudes and perception from moderate to strong moral attitude. It also showed that attendance and profile variates of age, sex, family income, occupation, and religion did not correlate to the moral attitude level of the respondents. This implied that participation in the study circle and the usage of the study material were the only factors that caused the significant difference in the mean score, and consequently, the leveling up of participants’ moral attitude. The number of participants in the discussions and activities from start to the last session improved from few to almost all, and the qualitative data generated through focus group discussion (FGD) and observation revealed highly favorable comments by respondents on various elements of the program

    Principios básicos de resonancia magnética cardiovascular (RMC): secuencias, planos de adquisición y protocolo de estudio

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    ABSTRACT Evaluation of the cardiovascular system with magnetic resonance (CMR) has become one of the most relevant and up-to-the-minute clinical applications of this diagnostic technique, as CMR makes possible an exact and reproducible study of the anatomy and function of the heart and great vessels. The complexity of this technique is mainly due to the anatomical location and orientation of the cardiovascular structures, the specific CMR sequences that have to be used and a lack of familiarity amongst radiologists regarding cardiovascular pathology. In this report the most basic principles of CMR are described. The clinical usefulness of anatomical, functional, and flow quantification sequences are discussed, conventional CMR acquisition planes are described, and an easy CMR study protocol is proposed

    Propuesta de un modelo de gesti?n bajo el esquema de la teor?a de restricci?n para incrementar la productividad en un establecimiento de salud de categor?a III-2

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    Esta investigaci?n tiene como prop?sito el mejorar la productividad, identificando los factores que determinan la implementaci?n efectiva en el Sistema Nacional de Salud de un establecimiento de Salud de categor?a III-2, y presentar una propuesta de metodolog?a que est? a disposici?n para ser replicable en todas las Instituciones de Salud de igual o menor complejidad, permitiendo conocer el comportamiento de las instituciones tanto a nivel gerencial como operativo, integrando y haciendo visible a trav?s de la cadena de valor los componentes asistenciales y administrativos involucrados en la prestaci?n de servicios para el ciudadano y los componentes del Sistema de Salud. La motivaci?n primordial es poder identificar con hechos concretos el proceso de atenci?n del paciente, desde su ingreso hasta la condici?n del egreso del establecimiento de salud, haciendo visible los cuellos de botella que limitan el flujo en cada paso de la atenci?n, cuya resoluci?n significa dar fluidez al proceso, desde el primer contacto con el paciente, el tratamiento de la enfermedad y su rehabilitaci?n

    First observations of oblique ionospheric sounding chirp signal in Mexico

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    The results of the first experiment of oblique ionospheric sounding (OIS) chirp signal reception in Mexico are reported. Maximal and Lowest Observed Frequencies variations were studied under the quiet Space Weather conditions. The diurnal ionospheric variations by OIS signal confirm the results based on GNSS data in the Mexican region. The best HF radio propagation conditions along the considered path are during morning and daytime hours. The multi-hop propagation is frequent. The interlayer propagation modes are present at nighttime

    A systematic review of the evidence for single stage and two stage revision of infected knee replacement

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    BACKGROUND: Periprosthetic infection about the knee is a devastating complication that may affect between 1% and 5% of knee replacement. With over 79 000 knee replacements being implanted each year in the UK, periprosthetic infection (PJI) is set to become an important burden of disease and cost to the healthcare economy. One of the important controversies in treatment of PJI is whether a single stage revision operation is superior to a two-stage procedure. This study sought to systematically evaluate the published evidence to determine which technique had lowest reinfection rates. METHODS: A systematic review of the literature was undertaken using the MEDLINE and EMBASE databases with the aim to identify existing studies that present the outcomes of each surgical technique. Reinfection rate was the primary outcome measure. Studies of specific subsets of patients such as resistant organisms were excluded. RESULTS: 63 studies were identified that met the inclusion criteria. The majority of which (58) were reports of two-stage revision. Reinfection rated varied between 0% and 41% in two-stage studies, and 0% and 11% in single stage studies. No clinical trials were identified and the majority of studies were observational studies. CONCLUSIONS: Evidence for both one-stage and two-stage revision is largely of low quality. The evidence basis for two-stage revision is significantly larger, and further work into direct comparison between the two techniques should be undertaken as a priority

    Polymorphisms within autophagy-related genes influence the risk of developing colorectal cancer: a meta-analysis of four large cohorts

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    The role of genetic variation in autophagy-related genes in modulating autophagy and cancer is poorly understood. Here, we comprehensively investigated the association of autophagy-related variants with colorectal cancer (CRC) risk and provide new insights about the molecular mechanisms underlying the associations. After meta-analysis of the genome-wide association study (GWAS) data from four independent European cohorts (8006 CRC cases and 7070 controls), two loci, DAPK2 (p = 2.19 × 10−5) and ATG5 (p = 6.28 × 10−4) were associated with the risk of CRC. Mechanistically, the DAPK2rs11631973G allele was associated with IL1 β levels after the stimulation of peripheral blood mononuclear cells (PBMCs) with Staphylococcus aureus (p = 0.002), CD24 + CD38 + CD27 + IgM + B cell levels in blood (p = 0.0038) and serum levels of en-RAGE (p = 0.0068). ATG5rs546456T allele was associated with TNF α and IL1 β levels after the stimulation of PBMCs with LPS (p = 0.0088 and p = 0.0076, respectively), CD14+CD16− cell levels in blood (p = 0.0068) and serum levels of CCL19 and cortisol (p = 0.0052 and p = 0.0074, respectively). Interestingly, no association with autophagy flux was observed. These results suggested an effect of the DAPK2 and ATG5 loci in the pathogenesis of CRC, likely through the modulation of host immune responses.This work was partially supported by grants from the Instituto de Salud Carlos III (Madrid, Spain; PI12/02688 and PI17/02256). CORSA was funded by the Austrian Research Promotion Agency (FFG) BRIDGE grant (no. 829675, to Andrea Gsur), the “Herzfelder’sche Familienstiftung” (grant to Andrea Gsur). Czech Republic CCS was funded by GACR grants (18–09709S, 19–10543S and 20–03997S), ProgresQ28/1.LF and UNCE/MED/006 grants. This article is based upon work from COST Action CA17118, supported by COST (European Cooperation in Science and Technology). A.K. is a recipient of a Ramalingaswami Re-Retry Faculty Fellowship (Grant; BT/RLF/Re-entry/38/2017) from the Department of Biotechnology (DBT), Government of India (GOI). V.M. received funding from the Agency for Management of University and Research Grants (AGAUR) of the Catalan Government grant 2017SGR723, the Instituto de Salud Carlos III, co-funded by FEDER funds–a way to build Europe–grants PI14-00613, PI17-00092 and the Spanish Association Against Cancer (AECC) Scientific Foundation grant GCTRA18022MORE. K.H. was supported by European Union Horizon 2020 grant No. 856620. We thank the CERCA Programme, Generalitat de Catalunya for institutional support

    Comparación de la castración quirúrgica al nacimiento versus inmunocastration sobre las características de la canal y carne en machos Holstein

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    El objetivo fue comparar el efecto de la castración quirúrgica al nacimiento vs immunocastración, sobre las características de la canal y carne en machos Holstein en engorda; se utilizaron 720 machos Holstein aproximadamente de 7 a 8 meses de edad con peso inicial de 240.82 kg. Se formaron 2 tratamientos con 4 corrales de 90 animales en cada uno: toros castrados quirúrgicamente que fueron castrados 24 h después del nacimiento y toros inmunocastrados vacunados con Bopriva aplicando cuatro dosis, al día 1, 21, 101 y 181 de engorda. Se tomaron pesos individuales en cada vacunación. Los animales se sacrificaron a los 242 días de engorda. A partir de la segunda vacunación se observaron diferencias (P0.05) entre tratamientos mientras que los valores de b*, C* y H* fueron más altos (P<0.05) en los animales inmunocastrados. Para fines de producción, el sacrificar los machos Holstein al nacimiento, se obtienen animales más pesados y con mejores características en la canal; sin embargo es importante evaluar el impacto del bienestar animal por la castración al nacimiento

    Performance and Operation of the CMS Electromagnetic Calorimeter

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    The operation and general performance of the CMS electromagnetic calorimeter using cosmic-ray muons are described. These muons were recorded after the closure of the CMS detector in late 2008. The calorimeter is made of lead tungstate crystals and the overall status of the 75848 channels corresponding to the barrel and endcap detectors is reported. The stability of crucial operational parameters, such as high voltage, temperature and electronic noise, is summarised and the performance of the light monitoring system is presented

    La Ilustración hispánica. Mestiza y universal

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    Catálogo de la exposición celebrada en la AECID (Madrid) de septiembre de 2017 a febrero de 2018Antecedentes y precursores de la Ilustración hispánica / Fermín del Pino -- La Escuela Universalista Hispánica o Española del siglo XVIII / Pedro Aullón de Haro -- El Galeón de Manila en la historia de la globalización / Davide Mombelli -- El Pacífico, Filipinas y los Mares del sur / Francisco G. Villanueva -- Expediciones de límites geográficos en América durante la segunda mitad del siglo XVIII / Carmen Martínez Martín -- Andrés, Hervás y la filología universal / Jesús García Gabaldón -- La Ilustración en Filipinas / Isaac Donoso -- La colaboración europea en materia científica. El período ilustrado / Fernando Miguel Pérez Herranz -- La salud como objetivo, la Real Expedición Filantrópica de la Vacuna : textos y contextos / Susana María Ramírez Martín -- El método del viaje / Joaquín Ibáñez Montoya -- La investigación basada en fuentes bibliográficas / Araceli Garcí
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