49 research outputs found
Using The Censored Gamma Distribution for Modeling Fractional Response Variables with an Application to Loss Given Default
Regression models for limited continuous dependent variables having a
non-negligible probability of attaining exactly their limits are presented. The
models differ in the number of parameters and in their flexibility. Fractional
data being a special case of limited dependent data, the models also apply to
variables that are a fraction or a proportion. It is shown how to fit these
models and they are applied to a Loss Given Default dataset from insurance to
which they provide a good fit
A dynamic nonstationary spatio-temporal model for short term prediction of precipitation
Precipitation is a complex physical process that varies in space and time.
Predictions and interpolations at unobserved times and/or locations help to
solve important problems in many areas. In this paper, we present a
hierarchical Bayesian model for spatio-temporal data and apply it to obtain
short term predictions of rainfall. The model incorporates physical knowledge
about the underlying processes that determine rainfall, such as advection,
diffusion and convection. It is based on a temporal autoregressive convolution
with spatially colored and temporally white innovations. By linking the
advection parameter of the convolution kernel to an external wind vector, the
model is temporally nonstationary. Further, it allows for nonseparable and
anisotropic covariance structures. With the help of the Voronoi tessellation,
we construct a natural parametrization, that is, space as well as time
resolution consistent, for data lying on irregular grid points. In the
application, the statistical model combines forecasts of three other
meteorological variables obtained from a numerical weather prediction model
with past precipitation observations. The model is then used to predict
three-hourly precipitation over 24 hours. It performs better than a separable,
stationary and isotropic version, and it performs comparably to a deterministic
numerical weather prediction model for precipitation and has the advantage that
it quantifies prediction uncertainty.Comment: Published in at http://dx.doi.org/10.1214/12-AOAS564 the Annals of
Applied Statistics (http://www.imstat.org/aoas/) by the Institute of
Mathematical Statistics (http://www.imstat.org
Using the Censored Gamma Distribution for Modeling Fractional Response Variables with an Application to Loss Given Default
Regression models for limited continuous dependent variables having a non-negligible probability of attaining exactly their limits are presented. The models differ in the number of parameters and in their flexibility. Fractional data being a special case of limited dependent data, the models also apply to variables that are a fraction or a proportion. It is shown how to fit these models and they are applied to a Loss Given Default dataset from insurance to which they provide a good fi
Problems with Using the Normal Distribution â and Ways to Improve Quality and Efficiency of Data Analysis
Background: The Gaussian or normal distribution is the most established model to characterize quantitative variation of original data. Accordingly, data are summarized using the arithmetic mean and the standard deviation, by x 6 SD, or with the standard error of the mean, x 6 SEM. This, together with corresponding bars in graphical displays has become the standard to characterize variation. Methodology/Principal Findings: Here we question the adequacy of this characterization, and of the model. The published literature provides numerous examples for which such descriptions appear inappropriate because, based on the ââ95 % range checkââ, their distributions are obviously skewed. In these cases, the symmetric characterization is a poor description and may trigger wrong conclusions. To solve the problem, it is enlightening to regard causes of variation. Multiplicative causes are by far more important than additive ones, in general, and benefit from a multiplicative (or log-) normal approach. Fortunately, quite similar to the normal, the log-normal distribution can now be handled easily and characterized at the level of the original data with the help of both, a new sign, x /, times-divide, and notation. Analogous to x 6 SD, it connects the multiplicative (or geometric) mean x * and the multiplicative standard deviation s * in the form x * x /s*, that is advantageous and recommended. Conclusions/Significance: The corresponding shift from the symmetric to the asymmetric view will substantially increas
Correction to: Two years later: Is the SARS-CoV-2 pandemic still having an impact on emergency surgery? An international cross-sectional survey among WSES members
Background: The SARS-CoV-2 pandemic is still ongoing and a major challenge for health care services worldwide. In the first WSES COVID-19 emergency surgery survey, a strong negative impact on emergency surgery (ES) had been described already early in the pandemic situation. However, the knowledge is limited about current effects of the pandemic on patient flow through emergency rooms, daily routine and decision making in ES as well as their changes over time during the last two pandemic years. This second WSES COVID-19 emergency surgery survey investigates the impact of the SARS-CoV-2 pandemic on ES during the course of the pandemic.
Methods: A web survey had been distributed to medical specialists in ES during a four-week period from January 2022, investigating the impact of the pandemic on patients and septic diseases both requiring ES, structural problems due to the pandemic and time-to-intervention in ES routine.
Results: 367 collaborators from 59 countries responded to the survey. The majority indicated that the pandemic still significantly impacts on treatment and outcome of surgical emergency patients (83.1% and 78.5%, respectively). As reasons, the collaborators reported decreased case load in ES (44.7%), but patients presenting with more prolonged and severe diseases, especially concerning perforated appendicitis (62.1%) and diverticulitis (57.5%). Otherwise, approximately 50% of the participants still observe a delay in time-to-intervention in ES compared with the situation before the pandemic. Relevant causes leading to enlarged time-to-intervention in ES during the pandemic are persistent problems with in-hospital logistics, lacks in medical staff as well as operating room and intensive care capacities during the pandemic. This leads not only to the need for triage or transferring of ES patients to other hospitals, reported by 64.0% and 48.8% of the collaborators, respectively, but also to paradigm shifts in treatment modalities to non-operative approaches reported by 67.3% of the participants, especially in uncomplicated appendicitis, cholecystitis and multiple-recurrent diverticulitis.
Conclusions: The SARS-CoV-2 pandemic still significantly impacts on care and outcome of patients in ES. Well-known problems with in-hospital logistics are not sufficiently resolved by now; however, medical staff shortages and reduced capacities have been dramatically aggravated over last two pandemic years
Diversity and ethics in trauma and acute care surgery teams: results from an international survey
Background Investigating the context of trauma and acute care surgery, the article aims at understanding the factors that can enhance some ethical aspects, namely the importance of patient consent, the perceptiveness of the ethical role of the trauma leader, and the perceived importance of ethics as an educational subject. Methods The article employs an international questionnaire promoted by the World Society of Emergency Surgery. Results Through the analysis of 402 fully filled questionnaires by surgeons from 72 different countries, the three main ethical topics are investigated through the lens of gender, membership of an academic or non-academic institution, an official trauma team, and a diverse group. In general terms, results highlight greater attention paid by surgeons belonging to academic institutions, official trauma teams, and diverse groups. Conclusions Our results underline that some organizational factors (e.g., the fact that the team belongs to a university context or is more diverse) might lead to the development of a higher sensibility on ethical matters. Embracing cultural diversity forces trauma teams to deal with different mindsets. Organizations should, therefore, consider those elements in defining their organizational procedures. Level of evidence Trauma and acute care teams work under tremendous pressure and complex circumstances, with their members needing to make ethical decisions quickly. The international survey allowed to shed light on how team assembly decisions might represent an opportunity to coordinate team member actions and increase performance
Oral or topical administration of L-arginine changes the expression of TGF and iNOS and results in early wounds healing
Photodissociation and photoionisation of atoms and molecules of astrophysical interest
Respiratory responses during affective picture viewing
Previous research has demonstrated covariation of physiological responding with judgments of valence and arousal. However, until now links between these affective dimensions and respiratory measures have not been extensively investigated. In this study, eight picture series of different affective valence and arousal level were shown to 30 subjects, while respiration, skin conductance level (SCL), heart rate (HR) and affective judgments were measured. With increasing pleasantness, inspiratory time lengthened, mean inspiratory flow decreased and thoracic breathing increased. With increasing arousal, inspiratory time and total breath duration shortened and mean inspiratory flow, minute ventilation, thoracic breathing and electrodermal activity increased. These findings confirm the importance of arousal in respiratory responding, but also indicate a modulatory role of affective valence.We propose that the arousal effects reflect energy mobilization in preparation to act, and thatthe valence effects might be a manifestation of an attention bias toward negative stimuli. [Authors]]]>
eng
oai:serval.unil.ch:BIB_4350
2022-02-19T02:20:17Z
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ElÚves en difficultés: la pédagogie compensatoire est-elle efficace ?
Doudin, PA
info:eu-repo/semantics/article
article
1996
Psychoscope, vol. 9, pp. 4-7
oai:serval.unil.ch:BIB_43500F74D76A
2022-02-19T02:20:17Z
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https://serval.unil.ch/notice/serval:BIB_43500F74D76A
The Apostle Philip, The Viper, The Leopard, and the Kid. The Masked Actors of a Religious Conflict in Hierapolis of Phrygia (Acts of Philip VIII-XV and Martyrdom)
Amsler, Frédéric
info:eu-repo/semantics/conferenceObject
inproceedings
1996
Society of Biblical Literature 1996 Seminar Papers, pp. 432-437
eng
oai:serval.unil.ch:BIB_4350488D87C6
2022-02-19T02:20:17Z
ehelvetica
openaire
documents
phdthesis
urnserval
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Etude du respect des mesures de prévention de la transmission verticale du virus de l'hépatite B chez les enfants nés dans les maternités des hÎpitaux publics du canton de Vaud
Guidon-Nidecker, M.
Université de Lausanne, Faculté de biologie et médecine
info:eu-repo/semantics/doctoralThesis
phdthesis
2013
<![CDATA[Actuellement, en Suisse, environ 1% des femmes en ùge de procréer ont une hépatite B chronique(8). En l'absence de mesures de prévention, le risque de transmission du virus de l'hépatite B, de la mÚre à son enfant, est estimé à 40%(3,4,5) lors de l'accouchement. Ce risque s'étend bien au-delà de la période périnatale. Les enfants infectés dans ces circonstances ont une probabilité de 90% de développer une infection chronique(5,7) et un quart meurent prématurément de cirrhose ou d'hépatocarcinome(2).
L'Office fĂ©dĂ©ral de la santĂ© publique recommande d'effectuer un dĂ©pistage antĂ©natal de l'antigĂšne HBsAg lors de toute grossesse(1) et d'effectuer une vaccination passive et active chez tous les enfants naissant d'une mĂšre avec une hĂ©patite B chronique. Cette prophylaxie doit ĂȘtre effectuĂ©e comme suit : immunoglobuline spĂ©cifique et lere dose de vaccin dans les 12 heures suivant la naissance (en maternitĂ©) ; 2eme dose de vaccin Ă 1 mois, 3eme dose de vaccin Ă 6 mois et contrĂŽle de la rĂ©ponse immune entre le 7eme et le 12eme mois (par le mĂ©decin traitant).
Cette étude vise à évaluer la compliance du systÚme de soins envers ces recommandations qui exigent l'intervention des maternités et des médecins traitants et qui s'étalent dans le temps. Pour ce faire, un recensement rétrospectif des enfants nés de mÚre avec une hépatite B chronique, en 2005 et 2006 dans 4 maternités vaudoises, a été effectué. Les mesures appliquées par les maternités, les informations transmises aux médecins traitants et les mesures appliquées par ces derniers ont été évaluées.
Sur un total de 10'412 parturientes testées, 70 présentent une infection chronique et 51 acceptent le recrutement dans l'étude (représentant un collectif de 54 enfants). En maternité, l'immunisation active et passive est effectuée chez tous les enfants. L'évidence qu'elle est effectuée dans les 12 heures suivant la naissance est fournie dans 61% des cas (mais dans 100% des dossiers dans lequel ce renseignement est consigné). La nécessité de poursuivre la vaccination n'est mentionné au médecin traitant que dans 15% des cas, et dans seulement 11% des cas les modalités du calendrier vaccinal sont précisées. La recommandation d'effectuer un contrÎle sérologique n'apparaßt dans aucun document de transmission.
Chez les médecins traitants, la 2eme dose de vaccin est administrée à 100% des enfants, mais seulement dans 15% des cas dans les délais recommandés. La 3eme dose de vaccination est administrée à 98% des enfants, mais seulement dans 43% des cas dans les délais recommandés. La sérologie de contrÎle n'est effectuée que chez 24% des enfants, et seulement dans 7% des cas dans les délais recommandés.
Les maternités appliquent les mesures de prophylaxie dans le délai imparti, tout au moins quand l'heure d'intervention est indiquée. Les médecins traitants sont rarement informés de la nécessité de compléter la vaccination et jamais des modalités ni de la nécessité d'effectuer un contrÎle sérologique. L'application des mesures de prévention par les médecins traitants est non conforme aux recommandations. Nous émettons l'hypothÚse que cet état reflÚte la carence d'information de la part des maternités et nous proposons que celles-ci utilisent un document de transmission standardisé qui indique précisément aux médecins traitants ce qui reste à faire, et quand, en matiÚre de prévention de l'hépatite B chez le nouveau-né/nourrisson