Inclusive sports and wellness practice in preschool educational institution

The article presents the experience of inclusive sports and recreation activities in preschool educational institution based on the health of childrenВ статье представлен опыт организации инклюзивной физкультурно-оздоровительной работы в дошкольном образовательном учреждении с учетом особенностей здоровья воспитаннико

Approaches for the design health educational environment

Described the approaches for the design health educational environment. As these environments presents health-environment ecologically safe environment, tolerant environment, psychologically safe environment, a non-violent environment creative environmentОписаны подходы к проектированию образовательной среды, в качестве целевого ориентира которой выбрано сохранение психического и физического здоровья обучающихся. В качестве таких сред представлены здоровьесберегающая среда, экологически безопасная среда, толерантная среда, психологически безопасная среда, ненасильственная среда, креативная сред

Features of subjective well-being as an indicator of socio-psychological security and social health of children with intellectual disabilities

Presents the results of research of subjective well-being of children with intellectual disabilities, who acts as the indicator of their socio-psychological safety and social healthПредставлены результаты исследования субъективного благополучия детей с нарушениями интеллекта, выступающего показателем их социально-психологической безопасности и социального здоровь

Duodenal Eosinophilia in Functional Dyspepsia

Aim: to present observation of a patient diagnosed with functional dyspepsia based on current guidelines, and having increased eosinophil counts in the biopsy specimen of duodenal mucosa. To consider possible causes of duodenal eosinophilia in the light of present-day concepts.Highlights. Patient K., 40 years old, complained of dyspeptic phenomena, the first appearance of which she had noted at the age of 18. The patient noted poor tolerance to canned and fermented foods, which provoked an increase in dyspepsia and sometimes caused watery diarrhea. The examination excluded “symptoms of concern”. Successful antihelicobacter eradication therapy was carried out. Morphological examination of the stomach showed phenomena of mild chronic inflammation without intestinal metaplasia or glandular atrophy. A biopsy of the mucosa of the descending part of the duodenum showed a moderate increase in the levels of mononuclears and eosinophils in its lamina propria without penetration into the epithelium of the villi or formation of clusters. The patient suffers from pollinosis; sensitization to birch pollen was diagnosed by a skin prick test. However, she has no oral allergy symptoms, which does not allow linking duodenal eosinophilia to food allergy. Based on current guidelines, the patient was diagnosed with functional dyspepsia. In addition to dietary restrictions, treatment courses with a proton pump inhibitor, itopride, and S-methylmethionine sulfonium chloride, which has an antihistamine effect, were recommended for periods of worsening dyspepsia.Conclusion. The clinical significance of duodenal eosinophilia and local histamine production in patients with a clinical diagnosis of functional dyspepsia deserves special attention. Triggering factors provoking the worsening of symptoms should be analyzed; in particular, a food diary and exclusion of food allergies are recommended. Histamine-neutralizing drugs may play a role in the treatment of FD with duodenal eosinophilia in the future

On the way from SARS-CoV-sensitive mice to murine COVID-19 model

The coronavirus disease 2019 (COVID-19) is a master killer which appeared suddenly and which has already claimed more than 200,000 human lives. In this situation, laboratories are in urgent need for a COVID-19 murine model to search for effective antiviral compounds. Here we propose a novel strategy for the development of mice that can be inoculated by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the COVID-19 causative agen

Constraints on jet quenching in p-Pb collisions at root s(NN)=5.02 TeV measured by the event-activity dependence of semi-inclusive hadron-jet distributions

CNPQ - CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICOFINEP - FINANCIADORA DE ESTUDOS E PROJETOSFAPESP - FUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULOThe ALICE Collaboration reports the measurement of semi-inclusive distributions of charged-particle jets recoiling from a high-transverse momentum trigger hadron in p-Pb collisions at root s(NN) = 5.02TeV. Jets are reconstructed from charged-particle tracks using the anti-k(T) algorithm with resolution parameter R = 0.2 and 0.4. A data-driven statistical approach is used to correct the uncorrelated background jet yield. Recoil jet distributions are reported for jet transverse momentum 15 < p(T,jet)(ch) < 50 GeV/c and are compared in various intervals of p-Pb event activity, based on charged-particle multiplicity and zero-degree neutral energy in the forward (Pb-going) direction. The semi-inclusive observable is self-normalized and such comparisons do not require the interpretation of p-Pb event activity in terms of collision geometry, in contrast to inclusive jet observables. These measurements provide new constraints on the magnitude of jet quenching in small systems at the LHC. In p-Pb collisions with high event activity, the average medium-induced out-of-cone energy transport for jets with R = 0.4 and 15 < p(T,jet)(ch) < 50 GeV/c is measured to be less than 0.4 GeV/c at 90% confidence, which is over an order of magnitude smaller than a similar measurement for central Pb-Pb collisions at root s(NN) = 2.76 TeV. Comparison is made to theoretical calculations of jet quenching in small systems, and to inclusive jet measurements in p-Pb collisions selected by event activity at the LHC and in d-Au collisions at RHIC.78395113CNPQ - CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICOFINEP - FINANCIADORA DE ESTUDOS E PROJETOSFAPESP - FUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULOCNPQ - CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICOFINEP - FINANCIADORA DE ESTUDOS E PROJETOSFAPESP - FUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULOSem informaçãoSem informaçãoSem informaçãoAgências de fomento estrangeiras apoiaram essa pesquisa, mais informações acesse artig

Constraining the magnitude of the chiral magnetic effect with event shape engineering in Pb-Pb collisions at root s(NN)=2.76 TeV

CNPQ - CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICOFINEP - FINANCIADORA DE ESTUDOS E PROJETOSFAPESP - FUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULOIn ultrarelativistic heavy-ion collisions, the event-by-event variation of the elliptic flow v(2) reflects fluctuations in the shape of the initial state of the system. This allows to select events with the same centrality but different initial geometry. This selection technique, Event Shape Engineering, has been used in the analysis of charge-dependent two-and three-particle correlations in Pb-Pb collisions at root s(NN) = 2.76 TeV. The two-particle correlator < cos(phi(alpha) - phi(ss))gt;, calculated for different combinations of charges alpha and beta, is almost independent of v(2) (for a given centrality), while the three-particle correlator < cos(phi(alpha) + phi(beta) - 2 Psi(2))gt; scales almost linearly both with the event v(2) and charged-particle pseudorapidity density. The charge dependence of the three-particle correlator is often interpreted as evidence for the Chiral Magnetic Effect (CME), a parity violating effect of the strong interaction. However, its measured dependence on v(2) points to a large non-CME contribution to the correlator. Comparing the results with Monte Carlo calculations including a magnetic field due to the spectators, the upper limit of the CME signal contribution to the three-particle correlator in the 10-50% centrality interval is found to be 26-33% at 95% confidence level.777151162CNPQ - CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICOFINEP - FINANCIADORA DE ESTUDOS E PROJETOSFAPESP - FUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULOCNPQ - CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICOFINEP - FINANCIADORA DE ESTUDOS E PROJETOSFAPESP - FUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULOSem informaçãoSem informaçãoSem informaçãoAgências de fomento estrangeiras apoiaram essa pesquisa, mais informações acesse artig

Measurement of Z(0)-boson production at large rapidities in Pb-Pb collisions at root s(NN)=5.02 TeV

The production of Z(0) bosons at large rapidities in Pb-Pb collisions at root s(NN) = 5.02 TeV is reported. Z(0) candidates are reconstructed in the dimuon decay channel (Z(0) -> mu(+) mu(-)), based on muons selected with pseudo-rapidity -4.0 20 GeV/c. The invariant yield and the nuclear modification factor, RAA, are presented as a function of rapidity and collision centrality. The value of R-AA for the 0-20% central Pb-Pb collisions is 0.67 +/- 0.11(stat.) +/- 0.03 (syst.) f 0.06(corr. syst.), exhibiting a deviation of 2.6 sigma from unity. The results are well-described by calculations that include nuclear modifications of the parton distribution functions, while the predictions using vacuum PDFs deviate from data by 2.3 sigma in the 0-90% centrality class and by 3 sigma in the 0-20% central collisions. (C) 2018 The Author(s). Published by Elsevier B.V.Peer reviewe

Longitudinal asymmetry and its effect on pseudorapidity distributions in Pb-Pb collisions at root s(NN)=2.76 TeV

First results on the longitudinal asymmetry and its effect on the pseudorapidity distributions in Pb-Pb collisions at root s(NN) = 2.76 TeV at the Large Hadron Collider are obtained with the ALICE detector. The longitudinal asymmetry arises because of an unequal number of participating nucleons from the two colliding nuclei, and is estimated for each event by measuring the energy in the forward neutron-Zero-Degree-Calorimeters (ZNs). The effect of the longitudinal asymmetry is measured on the pseudorapidity distributions of charged particles in the regions vertical bar eta vertical bar < 0.9, 2.8 < eta < 5.1 and -3.7 < eta < -1.7 by taking the ratio of the pseudorapidity distributions from events corresponding to different regions of asymmetry. The coefficients of a polynomial fit to the ratio characterise the effect of the asymmetry. A Monte Carlo simulation using a Glauber model for the colliding nuclei is tuned to reproduce the spectrum in the ZNs and provides a relation between the measurable longitudinal asymmetry and the shift in the rapidity (y(0)) of the participant zone formed by the unequal number of participating nucleons. The dependence of the coefficient of the linear term in the polynomial expansion, c(1), on the mean value of y(0) is investigated.Peer reviewe

First measurement of Ξc0 production in pp collisions at s=7 TeV

The production of the charm-strange baryon Csi0c is measured for the first time at the LHC via its semileptonic decay into e+Csi-νe in pp collisions at sqrt(s) = 7 TeV with the ALICE detector. The transverse momentum (pT) differential cross section multiplied by the branching ratio is presented in the interval 1 &lt; pT &lt; 8 GeV/c at mid-rapidity, |y| &lt; 0.5. The transverse momentum dependence of the Csi0c baryon production relative to the D0 meson production is compared to predictions of event generators with various tunes of the hadronisation mechanism, which are found to underestimate the measured cross- section ratio.The production of the charm-strange baryon Csi0c is measured for the first time at the LHC via its semileptonic decay into e+Csi-νe in pp collisions at sqrt(s) = 7 TeV with the ALICE detector. The transverse momentum (pT) differential cross section multiplied by the branching ratio is presented in the interval 1 &lt; pT &lt; 8 GeV/c at mid-rapidity, |y| &lt; 0.5. The transverse momentum dependence of the Csi0c baryon production relative to the D0 meson production is compared to predictions of event generators with various tunes of the hadronisation mechanism, which are found to underestimate the measured cross- section ratio