Broad-Spectrum Drugs Against Viral Agents

Development of antivirals has focused primarily on vaccines and on treatments for specific viral agents. Although effective, these approaches may be limited in situations where the etiologic agent is unknown or when the target virus has undergone mutation, recombination or reassortment. Augmentation of the innate immune response may be an effective alternative for disease amelioration. Nonspecific, broad-spectrum immune responses can be induced by double-stranded (ds)RNAs such as poly (ICLC), or oligonucleotides (ODNs) containing unmethylated deocycytidyl-deoxyguanosinyl (CpG) motifs. These may offer protection against various bacterial and viral pathogens regardless of their genetic makeup, zoonotic origin or drug resistance

The quantity surveyor's role in innovation generation, adoption and diffusion in the Australian construction industry

In 2004 the Building Research Innovation Technology and Environment (BRITE) Project conducted a survey on technological and organisational innovations in the Australian construction industry. This research uses the survey information to test the perception that there is a dichotomy between the self perceptions of quantity surveyors and the way that other stakeholders in the industry view the profession. A comparison is made of the survey responses given by quantity surveyors with those of the construction industry generally as well as with an identified group of high innovators in the industry. Quantity surveyors tend to innovate in the fields of data collection, management and monitoring processes which are perhaps not as visible to other members of the team as design innovations. Our research revealed that they widely believed innovation to have a positive effect on productivity but preferred informal measures of the value of such innovations. This is a somewhat surprising result as their core business is the collecting and measuring of information. To encourage improved innovation performance, quantity surveyors favoured increased training, more open attitudes and the removal of lowest cost tendering for quick profit. They specifically did not seek increased recognition or incentives as a way of improving performance. Generally they believed that it is design consultants who drive innovation in construction projects. Quantity surveyors perceived themselves to be supporters of innovation rather than blockers and saw themselves as contributors to a team but not usually as leaders of that team. Other industry groupings, however, did see the profession as potential blockers of innovation. Quantity surveying professionals need to be aware of the risk that other team members may see them more as “management’s auditors” rather than as genuine team contributors

25th New Zealand Singing School - Te Wananga Toi Waiata

Accompanist at the 25th New Zealand Singing School - Te Wananga Toi Waiata. 5 - 15th January 2011. School Director; Judy Bellingha

Providing Risk of the Environment’s Changing Climate Threats for Galleries, Libraries, Archives, & Museums (PROTECCT-GLAM) Data File

The data file was created as part of the IMLS-funded project, PROTECCT-GLAM: Risk of The Environment’s Changing Climate Threats for Galleries, Libraries, Archives, and Museums in an effort to gather the identities and georeferences of all galleries, libraries, archives, and museums located within the United States. The data file includes 22,388 archives, 21,189 libraries, and 29,781 museums