138 research outputs found

    Exploring the Role of Contextual Integrity in Electronic Medical Record (EMR) System Workaround Decisions: An Information Security and Privacy Perspective

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    Many healthcare providers in the US are seeking increased efficiency and effectiveness by rapidly adopting information technology (IT) solutions such as electronic medical record (EMR) systems. Legislation such as the Health Information Technology for Economic and Clinical Health Act (HITECH), which codified the adoption and “meaningful use” of electronic records in the US, has further spurred the industry-wide adoption of EMR. However, despite what are often large investments in EMR, studies indicate that the healthcare industry maintains a culture of system workarounds. Though perhaps not uncommon, the creation of informal workflows among healthcare workers is problematic for assuring information security and patient privacy, particularly when involving decisions of information management (e.g., information storage, retrieval, and/or transmission). Drawing on the framework of contextual integrity, we assert that one can often explain workarounds involving information transmissions in terms of trade-offs informed by context-specific informational norms. We surveyed healthcare workers and analyzed their willingness to engage in a series of EMR workaround scenarios. Our results indicate that contextual integrity provides a useful framework for understanding information transmission and workaround decisions in the health sector. Armed with these findings, managers and system designers should be better able to anticipate healthcare workers’ information transmission principles (e.g., privacy norms) and workaround patterns (e.g., usage norms). We present our findings and discuss their significance for research and practice

    Parents who wait: acknowledging the support needs and vulnerabilities of approved adopters during their wait to become adoptive parents

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    There is a significant amount of existing research exploring adoption policies, processes, and the experiences and safeguarding of children. However, although much research has children at the focus, little research has been conducted into the experiences of approved and waiting adopters. Where research has included adopters, focus tends to be on how adopters can aid an adoptive placement and what support they can provide to an adoptive child. In this article, the experiences of approved and waiting adopters are at the centre. This article reports on a digital ethnographic research project, which used unobtrusive methods to conduct a thematic analysis of over 600 posts made by waiting adopters on publically available UK online adoption forums in 2015. Online posts discussed the perceived over‐recruitment of adopters; the decision‐making behind adopters' initial preferences; and the negative emotional effects of the waiting period following approval. This article argues that more consideration needs to be given to the needs of and support for approved adopters whilst they wait for an adoptive child

    Deconstructing doing well; what can we learn from care experienced young people in England, Denmark and Norway?

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    This paper addresses the conceptualization of ‘outcomes’ for care experienced people through an in-depth longitudinal study of 75 young adults in Denmark, England and Norway. ‘Outcome’ studies have played a crucial role in raising awareness of the risk of disadvantage that care experienced people face, across a variety of domains including education and employment. These studies may have an unintended consequence, however, if care experienced people are predominantly viewed, and studied, through a problem-focused lens. The danger is that policy and research neglects other – perhaps less readily measurable – aspects of experience, including subjective understandings – what matters to care experienced people themselves. Our analyses are based on an in-depth qualitative longitudinal study, which explored meanings of ‘doing well’ over time among care experienced people (aged 16–32), all of whom were ‘successful’ in relation to traditional indicators of participation in education and/or employment (including voluntary work). Across countries, their accounts revealed the importance of attending to subjective and dynamic understandings of ‘doing well’, and the significance of ordinary, mundane and ‘do-able’ lives. Participants’ narratives highlight aspects of doing well that raise challenging questions about how traditional outcome indicators – and corresponding policy priorities – might better capture what young people themselves see as important. A narrow interpretation of outcomes may lead to misrecognition of what it means to do well, and so to a stigmatizing ‘way of seeing’ care experienced lives. A broader conceptualization of outcomes is necessary to recognize – and so to develop policy and services to support – the complex, dynamic relationality of doing well

    The Gaseous Electronics Conference radio‐frequency reference cell: A defined parallel‐plate radio‐frequency system for experimental and theoretical studies of plasma‐processing discharges

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    A ‘‘reference cell’’ for generating radio‐frequency (rf) glow discharges in gases at a frequency of 13.56 MHz is described. The reference cell provides an experimental platform for comparing plasma measurements carried out in a common reactor geometry by different experimental groups, thereby enhancing the transfer of knowledge and insight gained in rf discharge studies. The results of performing ostensibly identical measurements on six of these cells in five different laboratories are analyzed and discussed. Measurements were made of plasma voltage and current characteristics for discharges in pure argon at specified values of applied voltages, gas pressures, and gas flow rates. Data are presented on relevant electrical quantities derived from Fourier analysis of the voltage and current wave forms. Amplitudes, phase shifts, self‐bias voltages, and power dissipation were measured. Each of the cells was characterized in terms of its measured internal reactive components. Comparing results from different cells provides an indication of the degree of precision needed to define the electrical configuration and operating parameters in order to achieve identical performance at various laboratories. The results show, for example, that the external circuit, including the reactive components of the rf power source, can significantly influence the discharge. Results obtained in reference cells with identical rf power sources demonstrate that considerable progress has been made in developing a phenomenological understanding of the conditions needed to obtain reproducible discharge conditions in independent reference cells.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/70394/2/RSINAK-65-1-140-1.pd

    Identification and Clonal Characterisation of a Progenitor Cell Sub-Population in Normal Human Articular Cartilage

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    Background: Articular cartilage displays a poor repair capacity. The aim of cell-based therapies for cartilage defects is to repair damaged joint surfaces with a functional replacement tissue. Currently, chondrocytes removed from a healthy region of the cartilage are used but they are unable to retain their phenotype in expanded culture. The resulting repair tissue is fibrocartilaginous rather than hyaline, potentially compromising long-term repair. Mesenchymal stem cells, particularly bone marrow stromal cells (BMSC), are of interest for cartilage repair due to their inherent replicative potential. However, chondrocyte differentiated BMSCs display an endochondral phenotype, that is, can terminally differentiate and form a calcified matrix, leading to failure in long-term defect repair. Here, we investigate the isolation and characterisation of a human cartilage progenitor population that is resident within permanent adult articular cartilage. Methods and Findings: Human articular cartilage samples were digested and clonal populations isolated using a differential adhesion assay to fibronectin. Clonal cell lines were expanded in growth media to high population doublings and karyotype analysis performed. We present data to show that this cell population demonstrates a restricted differential potential during chondrogenic induction in a 3D pellet culture system. Furthermore, evidence of high telomerase activity and maintenance of telomere length, characteristic of a mesenchymal stem cell population, were observed in this clonal cell population. Lastly, as proof of principle, we carried out a pilot repair study in a goat in vivo model demonstrating the ability of goat cartilage progenitors to form a cartilage-like repair tissue in a chondral defect. Conclusions: In conclusion, we propose that we have identified and characterised a novel cartilage progenitor population resident in human articular cartilage which will greatly benefit future cell-based cartilage repair therapies due to its ability to maintain chondrogenicity upon extensive expansion unlike full-depth chondrocytes that lose this ability at only seven population doublings

    Beta-lactam antibiotics: from antibiosis to resistance and bacteriology

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    This review focuses on the era of antibiosis that led to a better understanding of bacterial morphology, in particlar the cell wall component peptidoglycan. This is an effort to take readers on a tour de force from the concept of antibiosis, to the serepidity of antibiotics, evolution of betalactam development, and the molecular biology of antibiotic resistance. These areas of research have culminated in a deeper understanding of microbiology, particularly in the area of bacterial cell wall synthesis and recycling. In spite of this knowledge, which has enabled design of new even more effective therapeutics to combat bacterial infection and has provided new research tools, antibiotic resistance remains a worldwide health care problem

    A community-based geological reconstruction of Antarctic Ice Sheet deglaciation since the Last Glacial Maximum

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    A robust understanding of Antarctic Ice Sheet deglacial history since the Last Glacial Maximum is important in order to constrain ice sheet and glacial-isostatic adjustment models, and to explore the forcing mechanisms responsible for ice sheet retreat. Such understanding can be derived from a broad range of geological and glaciological datasets and recent decades have seen an upsurge in such data gathering around the continent and Sub-Antarctic islands. Here, we report a new synthesis of those datasets, based on an accompanying series of reviews of the geological data, organised by sector. We present a series of timeslice maps for 20ka, 15ka, 10ka and 5ka, including grounding line position and ice sheet thickness changes, along with a clear assessment of levels of confidence. The reconstruction shows that the Antarctic Ice sheet did not everywhere reach the continental shelf edge at its maximum, that initial retreat was asynchronous, and that the spatial pattern of deglaciation was highly variable, particularly on the inner shelf. The deglacial reconstruction is consistent with a moderate overall excess ice volume and with a relatively small Antarctic contribution to meltwater pulse 1a. We discuss key areas of uncertainty both around the continent and by time interval, and we highlight potential priorit. © 2014 The Authors
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