A study of the kinematics and binary-induced shaping of the planetary nebula HaTr 4

We present the first detailed spatio-kinematical analysis and modelling of the planetary nebula HaTr 4, one of few known to contain a post-common-envelope central star system. Common envelope evolution is believed to play an important role in the shaping of planetary nebulae, but the exact nature of this role is yet to be understood. High spatial- and spectral- resolution spectroscopy of the [OIII]5007 nebular line obtained with VLT-UVES are presented alongside deep narrowband Ha+[NII]6584 imagery obtained using EMMI-NTT, and together the two are used to derive the three-dimensional morphology of HaTr 4. The nebula is found to display an extended ovoid morphology with an enhanced equatorial region consistent with a toroidal waist - a feature believed to be typical amongst planetary nebulae with post-common-envelope central stars. The nebular symmetry axis is found to lie perpendicular to the orbital plane of the central binary, concordant with the idea that the formation and evolution of HaTr 4 has been strongly influenced by its central binary.Comment: 9 pages, 5 figures, accepted for publication in MNRA

A survey on cellular and engineered tissue therapies in Europe in 2008

Cellular therapy is an evolving investigational treatment modality in regenerative medicine, but little published information is available on its current use. Starting from the established European group for Blood and Marrow Transplantation activity survey on hematopoietic stem cell transplantation, a joint committee of four major scientific organizations made a coordinated attempt to collect detailed information in Europe for the year 2008. Thirty-three teams from 16 countries reported data on 656 patients to a "novel cellular therapy" survey, which were combined to additional 384 records reported to the standard European group for Blood and Marrow Transplantation survey. Indications were cardiovascular (29%; 100% autologous), musculoskeletal (18%; 97% autologous), neurological (9%; 39% autologous), epithelial/parenchymal (9%; 18% autologous), autoimmune diseases (12%; 77% autologous), or graft-versus-host disease (23%; 13% autologous). Reported cell types were hematopoietic stem cells (39%), mesenchymal stromal cells (47%), chondrocytes (5%), keratinocytes (7%), myoblasts (2%), and others (1%). In 51% of the grafts, cells were delivered after expansion; in 4% of the cases, cells were transduced. Cells were delivered intravenously (31%), intraorgan (45%), on a membrane or gel (14%), or using three-dimensional scaffolds (10%). This data collection platform is expected to capture and foresee trends for novel cellular therapies in Europe, and warrants further consolidation and extension

How low can you go? Towards a hierarchy of grey literature.

In recent times health sciences librarians have become increasingly involved in working closely with researchers who are undertaking literature reviews (often, but not always, systematic literature reviews). Due to the evidence-based push throughout the medical and health practice area, strong database searching skills have become essential to locate and identify the research necessary to inform practice. These are skills that librarians already have. In hospitals and universities, librarians have been heartened to find their expertise openly acknowledged as their role dovetails neatly into a position of strength. Working with researchers we find our opinions are sought and valued, and this extends to questioning our knowledge of the grey literature. While searching the published (black) literature is a given, there is a growing recognition that grey literature should be included to fully reflect the existing evidential base. Herein lies the rub. Without a clearly established hierarchy, what grey literature is admissible: particularly if we consider grey resources other than the unpublished equivalents of traditional studies and trials? Literature reviews need to include the most significant research available. And that might mean conference papers, reports, legislation or working papers - all grey. This paper examines the variety, relevance, advantages and disadvantages of grey literature and where it might ‘sit’ in the overall research picture

Can uptake of public health interventions be improved by including grey literature in the evidence-base?

Copyright © 2016 TextRelease. Published version of the paper reproduced here with permission from the publisher.Interventions to prevent obesity are not working. Despite the substantial efforts of a multiplicity of interventions and strategies from the public health sector, by 2025 Australian adult obesity rates are predicted to rise by 65%. There is little doubt that increased physical activity/decreased sedentary behaviour combined with dietary intervention produces an outcome of reduced BMI: this is the science of weight loss and not in dispute, though a profusion of RCTs continue to be conducted along similar lines and academic journals continue to publish them. Policy in this area abounds but practical long-term successes remain elusive. What is often missing from the debate is acknowledgement and understanding of the public’s resistance to uptake of obesity prevention interventions. This crucial information can be gleaned from the grey literature. To be genuinely evidence-informed, policy needs to access the broadest literature base and include both published and unpublished sources. Grey literature includes surveys, public opinion, crowdsourcing, social media, theses and conference papers, issues and working papers, technical reports, unpublished studies and projects, newspapers and blogs. It is vital to consider these sources in the evidence-base to balance the science of obesity. Grey literature is where societal attitudes, beliefs, values and opinions might be reasonably expected to be found, and also where pilot programs and case studies assessing the feasibility of public health interventions will have been reported. The degree to which this literature has been accessed and incorporated into the evidence that informs policy arguably has an impact on the ultimate success or sustained “take-up” of an intervention

The influence of binarity on the morpho-kinematics of planetary nebulae

The role of central star binarity in the shaping of planetary nebulae (PNe) has been the subject of much debate, with single stars believed to be incapable of producing the most highly collimated morphologies. However, observational support for binary-induced shaping has been sadly lacking. Here, we highlight the results of a continuing programme to spatio-kinematically model the morphologies of all PNe known to contain a close binary central star. Spatio-kinematical modelling is imperative for these objects, as it circumvents the degeneracy between morphology and orientation which can adversely affect determinations of morphology based on imaging alone. Furthermore, spatio-kinematical modelling accurately determines the orientation of the nebular shell, allowing the theoretically predicted perpendicular alignment, between nebular symmetry axis and binary orbital plane, to be tested. To date, every PN subjected to this investigation has displayed the predicted alignment, indicating that binarity has played an important role in the formation and evolution of these nebulae. The further results from this programme will be key, not only in determining whether binary interaction is responsible for shaping the studied PNe, but also in assessing the importance of binarity in the formation and evolution of all PNe in general.Comment: 2 pages, 2 tables, proceedings of the IAU Symposium No. 283, Planetary Nebulae: An Eye to the Futur