A Gravimetric Support Network for Very Long Baseline Atom Interferometry

With the introduction of portable atom interferometers (AI), a genuinely independent method for the determination of g is available for the first time since the introduction of laser interferometer based instruments. Current AIs offer several advantages and already reach the accuracy of classical sensors. Additionally, a small number of stationary experiments were implemented for research in fundamental physics and geodesy. These instruments, extending the free fall distance of atoms to several meters, allow for longer evolution times of the wave function, thereby increasing the sensitivity of the AI compared to decimetres in portable devices. The construction of an AI with a 9 m interaction zone is currently being completed at Leibniz University Hannover. The knowledge of g and its gradient is required for the evaluation of systematic effects and uncertainties in AI experiments. Therefore, a gravimetric control network connected to one absolute gravimeter pier was established and repeatedly observed during the construction of the Very Long Baseline Atom Interferometry facility (VLBAI). Before the installation of the instrument, this network included the central axis of the VLBAI and one vertical off-axis parallel profile. The latter profile can also be observed during operation of the VLBAI. The effect of local gravity changes, e. g., hydrology, is comparable to 1 nm/s² on both axes. The gravimetric measurements serve as a reference during initial tests of the VLBAI. Repeated observations in the future will be used to characterize the effect of local hydrology and other mass variations along the vertical axis. A model of the research building and groundwater level monitoring supplements the gravimetric network. As the VLBAI is capable of measuring g and its vertical gradient with higher accuracy (<1 nm/s²) than classical instruments, the model will be used to transfer g to a gravimetry laboratory for gravimeter comparisons. We present our strategy for gravimetric control of the VLBAI. This will provide a reference at first and will later be used to establish the VLBAI as a reference for gravimeter comparisons. The results of the first gravimetric campaigns and the comparison with the model of the VLBAI environment show an agreement within the instrumental uncertainties of the relative gravimeters used

Gravity field modelling for the Hannover 10 m atom interferometer

Stable gravimetric measurements over timescales from several days to decades are required to provide relevant insight into geophysical processes or to realise a gravimetric reference frame. Users of absolute gravimeters participate in CIPM or RMO key comparisons with a metrological reference in order to monitor the temporal stability of the instruments and determine the bias to that reference. These comparisons provide the reference values of highest accuracy, around 10 nm/s², compared to the calibration against a single gravimeter operated at a metrological institute. The construction of stationary, large scale atom interferometers paves the way towards a new measurement standard in absolute gravimetry used as a reference with a potential stability better than 1 nm/s² at 1 second integration time. At the Leibniz University Hannover, we are currently building such a very long baseline atom interferometer with a 10 m high vertical free fall zone. Additionally, a 3D model of the instrument and its environment is adapted to derive the change of gravity due to the setup of the instrument. The model is then compared to episodic gravimetric measurements. The knowledge of local gravity and its gradient along and around the baseline is required to establish the instrument's uncertainty budget and enable transfers of gravimetric measurements to nearby devices for comparison and calibration purposes. We report on the progress of the gravimetric measurements and modelling of g inside and near the instrument in parallel to the construction of the atom interferometer

Opportunities and Alternatives of Modern Radiation Oncology and Surgery for the Management of Resectable Brain Metastases.

Postsurgical radiotherapy (RT) has been early proven to prevent local tumor recurrence, initially performed with whole brain RT (WBRT). Subsequent to disadvantageous cognitive sequalae for the patient and the broad distribution of modern linear accelerators, focal irradiation of the tumor has omitted WBRT in most cases. In many studies, the effectiveness of local RT of the resection cavity, either as single-fraction stereotactic radiosurgery (SRS) or hypo-fractionated stereotactic RT (hFSRT), has been demonstrated to be effective and safe. However, whereas prospective high-level incidence is still lacking on which dose and fractionation scheme is the best choice for the patient, further ablative techniques have come into play. Neoadjuvant SRS (N-SRS) prior to resection combines straightforward target delineation with an accelerated post-surgical phase, allowing an earlier start of systemic treatment or rehabilitation as indicated. In addition, low-energy intraoperative RT (IORT) on the surgical bed has been introduced as another alternative to external beam RT, offering sterilization of the cavity surface with steep dose gradients towards the healthy brain. This consensus paper summarizes current local treatment strategies for resectable brain metastases regarding available data and patient-centered decision-making

Penilaian Kinerja Keuangan Koperasi di Kabupaten Pelalawan

This paper describe development and financial performance of cooperative in District Pelalawan among 2007 - 2008. Studies on primary and secondary cooperative in 12 sub-districts. Method in this stady use performance measuring of productivity, efficiency, growth, liquidity, and solvability of cooperative. Productivity of cooperative in Pelalawan was highly but efficiency still low. Profit and income were highly, even liquidity of cooperative very high, and solvability was good

Juxtaposing BTE and ATE – on the role of the European insurance industry in funding civil litigation

One of the ways in which legal services are financed, and indeed shaped, is through private insurance arrangement. Two contrasting types of legal expenses insurance contracts (LEI) seem to dominate in Europe: before the event (BTE) and after the event (ATE) legal expenses insurance. Notwithstanding institutional differences between different legal systems, BTE and ATE insurance arrangements may be instrumental if government policy is geared towards strengthening a market-oriented system of financing access to justice for individuals and business. At the same time, emphasizing the role of a private industry as a keeper of the gates to justice raises issues of accountability and transparency, not readily reconcilable with demands of competition. Moreover, multiple actors (clients, lawyers, courts, insurers) are involved, causing behavioural dynamics which are not easily predicted or influenced. Against this background, this paper looks into BTE and ATE arrangements by analysing the particularities of BTE and ATE arrangements currently available in some European jurisdictions and by painting a picture of their respective markets and legal contexts. This allows for some reflection on the performance of BTE and ATE providers as both financiers and keepers. Two issues emerge from the analysis that are worthy of some further reflection. Firstly, there is the problematic long-term sustainability of some ATE products. Secondly, the challenges faced by policymakers that would like to nudge consumers into voluntarily taking out BTE LEI

Severe early onset preeclampsia: short and long term clinical, psychosocial and biochemical aspects

Preeclampsia is a pregnancy specific disorder commonly defined as de novo hypertension and proteinuria after 20 weeks gestational age. It occurs in approximately 3-5% of pregnancies and it is still a major cause of both foetal and maternal morbidity and mortality worldwide1. As extensive research has not yet elucidated the aetiology of preeclampsia, there are no rational preventive or therapeutic interventions available. The only rational treatment is delivery, which benefits the mother but is not in the interest of the foetus, if remote from term. Early onset preeclampsia (<32 weeks’ gestational age) occurs in less than 1% of pregnancies. It is, however often associated with maternal morbidity as the risk of progression to severe maternal disease is inversely related with gestational age at onset2. Resulting prematurity is therefore the main cause of neonatal mortality and morbidity in patients with severe preeclampsia3. Although the discussion is ongoing, perinatal survival is suggested to be increased in patients with preterm preeclampsia by expectant, non-interventional management. This temporising treatment option to lengthen pregnancy includes the use of antihypertensive medication to control hypertension, magnesium sulphate to prevent eclampsia and corticosteroids to enhance foetal lung maturity4. With optimal maternal haemodynamic status and reassuring foetal condition this results on average in an extension of 2 weeks. Prolongation of these pregnancies is a great challenge for clinicians to balance between potential maternal risks on one the eve hand and possible foetal benefits on the other. Clinical controversies regarding prolongation of preterm preeclamptic pregnancies still exist – also taking into account that preeclampsia is the leading cause of maternal mortality in the Netherlands5 - a debate which is even more pronounced in very preterm pregnancies with questionable foetal viability6-9. Do maternal risks of prolongation of these very early pregnancies outweigh the chances of neonatal survival? Counselling of women with very early onset preeclampsia not only comprises of knowledge of the outcome of those particular pregnancies, but also knowledge of outcomes of future pregnancies of these women is of major clinical importance. This thesis opens with a review of the literature on identifiable risk factors of preeclampsia

Search for stop and higgsino production using diphoton Higgs boson decays

Results are presented of a search for a "natural" supersymmetry scenario with gauge mediated symmetry breaking. It is assumed that only the supersymmetric partners of the top-quark (stop) and the Higgs boson (higgsino) are accessible. Events are examined in which there are two photons forming a Higgs boson candidate, and at least two b-quark jets. In 19.7 inverse femtobarns of proton-proton collision data at sqrt(s) = 8 TeV, recorded in the CMS experiment, no evidence of a signal is found and lower limits at the 95% confidence level are set, excluding the stop mass below 360 to 410 GeV, depending on the higgsino mass