El papel de enfermería en la seguridad del paciente

Se realizó una revisión documental en la que analiza la evolución de la seguridad del paciente y la adopción de esta como una cultura institucional en el momento de la prestación de servicios de salud, teniendo esto como resultado una mejora en la percepción de calidad y el mejoramiento continuo en los procesos institucionales, que demanda de los profesionales de enfermería un arduo trabajo en el fortalecimiento y empoderamiento de todos los miembros del equipo de salud, para poder lograr que en todas las instituciones se hable el mismo idioma en lo relacionado con seguridad del paciente. En el análisis realizado se encontró que el papel de enfermería es muy importante, ya que los profesionales de enfermería son los encargados del cuidado directo en cada una de las etapas, desde la prevención hasta la rehabilitación. Esta revisión documental se realizó desde marzo de 2019 hasta mayo del mismo año. Se pudo concluir que, independientemente del servicio de salud o el lugar donde se encuentra dicha entidad prestadora de servicios de salud, se presentan eventos adversos debido a múltiples factores, pero con la adopción de la cultura de seguridad del paciente se pueden disminuir y en muchos casos prevenir. Además, se resalta la importancia del rol del profesional de enfermería en el empoderamiento de la seguridad del paciente en las instituciones de servicios de salud

Diseño de un programa de farmacovigilancia en un establecimiento farmacéutico independiente

Los programas de farmacovigilancia son importantes debido a que posibilita efectuar seguimiento de manera confiable y seguridad de los medicamentos empleados por la comunidad bajo condiciones no supervisadas. Este documento puntualiza los procesos desarrollados para llevar a cabo el funcionamiento de un programa de farmacovigilancia en un establecimiento farmacéutico independiente en la comuna dos (2) de la ciudad de Neiva, con el objetivo de establecer los mecanismos para gestionar de forma oportuna los eventos adversos que pueden suceder al momento de administrar un de medicamento dispensado por el personal de la salud del establecimiento, a través de la detección, comprensión, evaluación y prevención de los eventos adversos o algún otro Problema Relacionado con Medicamentos (PRM), evitando el incremento de costos en el tratamiento y lesiones a la salud ocasionando discapacidad o incapacidad resultantes de estos sucesos.Pharmacovigilance programs are important because they make it possible to reliably and safely monitor medicines used by the community under unsupervised conditions. This document specifies the processes developed to carry out the operation of a pharmacovigilance program in an independent pharmaceutical establishment in commune 2 of the city of Neiva, with the aim of establishing mechanisms to manage adverse events that may occur in a timely manner. at the time of administering a medication dispensed by the health personnel of the establishment, through the detection, understanding, evaluation and prevention of adverse events or some other Problem Related to Medications (PRM), avoiding the increase in costs in the treatment and health injuries causing disability or incapacity resulting from these events

The Fourteenth Data Release of the Sloan Digital Sky Survey: First Spectroscopic Data from the extended Baryon Oscillation Spectroscopic Survey and from the second phase of the Apache Point Observatory Galactic Evolution Experiment

The fourth generation of the Sloan Digital Sky Survey (SDSS-IV) has been in operation since July 2014. This paper describes the second data release from this phase, and the fourteenth from SDSS overall (making this, Data Release Fourteen or DR14). This release makes public data taken by SDSS-IV in its first two years of operation (July 2014-2016). Like all previous SDSS releases, DR14 is cumulative, including the most recent reductions and calibrations of all data taken by SDSS since the first phase began operations in 2000. New in DR14 is the first public release of data from the extended Baryon Oscillation Spectroscopic Survey (eBOSS); the first data from the second phase of the Apache Point Observatory (APO) Galactic Evolution Experiment (APOGEE-2), including stellar parameter estimates from an innovative data driven machine learning algorithm known as "The Cannon"; and almost twice as many data cubes from the Mapping Nearby Galaxies at APO (MaNGA) survey as were in the previous release (N = 2812 in total). This paper describes the location and format of the publicly available data from SDSS-IV surveys. We provide references to the important technical papers describing how these data have been taken (both targeting and observation details) and processed for scientific use. The SDSS website (www.sdss.org) has been updated for this release, and provides links to data downloads, as well as tutorials and examples of data use. SDSS-IV is planning to continue to collect astronomical data until 2020, and will be followed by SDSS-V.Comment: SDSS-IV collaboration alphabetical author data release paper. DR14 happened on 31st July 2017. 19 pages, 5 figures. Accepted by ApJS on 28th Nov 2017 (this is the "post-print" and "post-proofs" version; minor corrections only from v1, and most of errors found in proofs corrected

Glucose Depletion in the Airway Surface Liquid Is Essential for Sterility of the Airways

Diabetes mellitus predisposes the host to bacterial infections. Moreover, hyperglycemia has been shown to be an independent risk factor for respiratory infections. The luminal surface of airway epithelia is covered by a thin layer of airway surface liquid (ASL) and is normally sterile despite constant exposure to bacteria. The balance between bacterial growth and killing in the airway determines the outcome of exposure to inhaled or aspirated bacteria: infection or sterility. We hypothesized that restriction of carbon sources –including glucose– in the ASL is required for sterility of the lungs. We found that airway epithelia deplete glucose from the ASL via a novel mechanism involving polarized expression of GLUT-1 and GLUT-10, intracellular glucose phosphorylation, and low relative paracellular glucose permeability in well-differentiated cultures of human airway epithelia and in segments of airway epithelia excised from human tracheas. Moreover, we found that increased glucose concentration in the ASL augments growth of P. aeruginosa in vitro and in the lungs of hyperglycemic ob/ob and db/db mice in vivo. In contrast, hyperglycemia had no effect on intrapulmonary bacterial growth of a P. aeruginosa mutant that is unable to utilize glucose as a carbon source. Our data suggest that depletion of glucose in the airway epithelial surface is a novel mechanism for innate immunity. This mechanism is important for sterility of the airways and has implications in hyperglycemia and conditions that result in disruption of the epithelial barrier in the lung

Conferencia internacional. Desafíos de la Investigación e innovación en tiempos de Covid-19

En 2018, Treinta y nueve estudiantes femeninas del X ciclo del periodo 2018-1 de la escuela de Psicología de una universidad particular del cono norte de Lima, ellas han descrito el romance de su personas cercanas a ellas. Se analizaron los 266 casos de parejas de enamorados estaban el rango de 17 a 25 años. El instrumento que se usó fue una CUESTIONARIO CUPIDO que es una escala nominal de conductas donde las estudiantes de psicología clasificaban los comportamientos en categorías preestablecidas, claramente definidas y mutuamente excluyentes. La conclusión más importante del estudio observacional fue que las parejas analizadas en un 64.4 % la mujer ero atrajo al varón y después el varón emo conectó con la mujer. También han observado otro estilo de romance cuando el varón ero atrajo a la mujer por su cuerpo atracción y después la mujer fue la que emo conectó con el varón y observaron este hecho en un 35.6 % de los casos

The Caldera. No. 22

“Ten fe ciega no en tu capacidad para el triunfo, sino en el ardor con que lo deseas. Ama a tu arte como a tu novia, dándole todo tu corazón” Horacio Quiroga Los retos de la educación del siglo XXI son cada vez más altos; el perfil de un profesional, en cualquier ámbito, requiere reunir una serie de cualidades, de capacidades, de destrezas y de habilidades, que le permitan, a cada persona, sobresalir entre todos los demás; Unab Creative, es el Centro de Creatividad, Innovación y Emprendimiento, en donde se están gestando toda una serie de propuestas que lleven a nuestros estudiantes, del Instituto Caldas y de la UNAB, a convertirse en esos profesionales que el mundo reclama; así, en nuestras aulas de clase, se despierta la curiosidad de los niños y jóvenes y se les permite, mediante una educación basada en la comprensión, aplicar sus saberes, de las diferentes disciplinas, a nuevas situaciones, a nuevos contextos, de una manera flexible y creativa.Editorial…02 Índice…04 Inner sameness…Identidad; Por: Gisela Afanador Díaz…06 Belouga is at caldas school; Por: Mireya Martinez Silva…10 Perfiles Caldistas; Por María Andrea Puyana…11 Bioweblearns; Por: Mariana Suarez Pacheco, María Camila Cervera Rey …13 Encuentro líderes estudiantiles; Por: Matías Gómez Buitrago, Santiago Pérez Valencia…15 Un profesor inolvidable; Por: Laura Prada Taborda, Gabriela Almeyda Carreño…20 Creatividad en el instituto caldas…28 V Concurso Intercolegiado de Oratoria; Por: Andrés Felipe Galeano Fontecha…29 Expresiones Caldistas…33 La presencia de Joseph Conrad en Horacio Quiroga a partir de la relación entre los cuentos “Los idiotas” y “La gallina degollada”; Por: Profesora Kelly Johanna Palacios…58 Bibliografía…63 Galeria De Imágenes…64Have blind faith not in your ability to succeed, but in the ardor with which you desire it. Love your art as your girlfriend, giving her all your heart ”Horacio Quiroga The challenges of education in the 21st century are increasingly high; The profile of a professional, in any field, requires gathering a series of qualities, capacities, skills and abilities, which allows each person to stand out from all others; Unab Creative is the Center for Creativity, Innovation and Entrepreneurship, where a whole series of proposals are being developed that will lead our students, from the Caldas Institute and UNAB, to become those professionals that the world demands; Thus, in our classrooms, the curiosity of children and young people is awakened and they are allowed, through an education based on understanding, to apply their knowledge, from different disciplines, to new situations, to new contexts, in a way flexible and creative

Cumulative Genetic Score and C9orf72 Repeat Status Independently Contribute to Amyotrophic Lateral Sclerosis Risk in 2 Case-Control Studies

[Background and Objectives] Most patients with amyotrophic lateral sclerosis (ALS) lack a monogenic mutation. This study evaluates ALS cumulative genetic risk in an independent Michigan and Spanish replication cohort using polygenic scores.[Methods] Participant samples from University of Michigan were genotyped and assayed for the chromosome 9 open reading frame 72 hexanucleotide expansion. Final cohort size was 219 ALS and 223 healthy controls after genotyping and participant filtering. Polygenic scores excluding the C9 region were generated using an independent ALS genome-wide association study (20,806 cases, 59,804 controls). Adjusted logistic regression and receiver operating characteristic curves evaluated the association and classification between polygenic scores and ALS status, respectively. Population attributable fractions and pathway analyses were conducted. An independent Spanish study sample (548 cases, 2,756 controls) was used for replication.[Results] Polygenic scores constructed from 275 single-nucleotide variation (SNV) had the best model fit in the Michigan cohort. An SD increase in ALS polygenic score associated with 1.28 (95% CI 1.04–1.57) times higher odds of ALS with area under the curve of 0.663 vs a model without the ALS polygenic score (p value = 1 × 10−6). The population attributable fraction of the highest 20th percentile of ALS polygenic scores, relative to the lowest 80th percentile, was 4.1% of ALS cases. Genes annotated to this polygenic score enriched for important ALS pathomechanisms. Meta-analysis with the Spanish study, using a harmonized 132 single nucleotide variation polygenic score, yielded similar logistic regression findings (odds ratio: 1.13, 95% CI 1.04–1.23).[Discussion] ALS polygenic scores can account for cumulative genetic risk in populations and reflect disease-relevant pathways. If further validated, this polygenic score will inform future ALS risk models.National ALS Registry/CDC/ATSDR (1R01TS000289); National ALS Registry/CDC/ATSDR CDCP-DHHS-US (CDC/ATSDR 200-2013-56856); NIEHS K23ES027221; NIEHS R01ES030049; NINDS R01NS127188, ALS Association (20-IIA-532), the Dr. Randall W. Whitcomb Fund for ALS Genetics, the Peter R. Clark Fund for ALS Research, the Scott L. Pranger ALS Clinic Fund, and the NeuroNetwork for Emerging Therapies at the University of Michigan. This work was supported in part by the Intramural Research Program of the NIH, National Institute on Aging (Z01-AG000949-02). Project “ALS Genetic study in Madrid Autonomous Community” funded by “ESTRATEGIAS FRENTE A ENFERMEDADES NEURODEGENERATIVAS” from Spanish Ministry of Health.Peer reviewe

Formación y desarrollo profesional docente. El enseñante y su desarrollo profesional según los medios de comunicación en prospectiva 2030

Fil: Bazzanella, María Cecilia. Universidad Católica de Córdoba. Facultad de Educación; ArgentinaFil: Boccardo, Silvia del Carmén. Universidad Católica de Córdoba. Facultad de Educación; Argentina.Fil: Cangelosi, Daniel Horacio. Universidad Católica de Córdoba. Facultad de Educación; ArgentinaFil: Capdevila, Miriam Inés. Universidad Católica de Córdoba. Facultad de Educación; Argentina

Cardiovascular disease, chronic kidney disease, and diabetes mortality burden of cardiometabolic risk factors from 1980 to 2010: a comparative risk assessment

Background High blood pressure, blood glucose, serum cholesterol, and BMI are risk factors for cardiovascular diseases and some of these factors also increase the risk of chronic kidney disease and diabetes. We estimated mortality from cardiovascular diseases, chronic kidney disease, and diabetes that was attributable to these four cardiometabolic risk factors for all countries and regions from 1980 to 2010. Methods We used data for exposure to risk factors by country, age group, and sex from pooled analyses of populationbased health surveys. We obtained relative risks for the eff ects of risk factors on cause-specifi c mortality from metaanalyses of large prospective studies. We calculated the population attributable fractions for- each risk factor alone, and for the combination of all risk factors, accounting for multicausality and for mediation of the eff ects of BMI by the other three risks. We calculated attributable deaths by multiplying the cause-specifi c population attributable fractions by the number of disease-specifi c deaths. We obtained cause-specifi c mortality from the Global Burden of Diseases, Injuries, and Risk Factors 2010 Study. We propagated the uncertainties of all the inputs to the fi nal estimates. Findings In 2010, high blood pressure was the leading risk factor for deaths due to cardiovascular diseases, chronic kidney disease, and diabetes in every region, causing more than 40% of worldwide deaths from these diseases; high BMI and glucose were each responsible for about 15% of deaths, and high cholesterol for more than 10%. After accounting for multicausality, 63% (10\ub78 million deaths, 95% CI 10\ub71\u201311\ub75) of deaths from these diseases in 2010 were attributable to the combined eff ect of these four metabolic risk factors, compared with 67% (7\ub71 million deaths, 6\ub76\u20137\ub76) in 1980. The mortality burden of high BMI and glucose nearly doubled from 1980 to 2010. At the country level, age-standardised death rates from these diseases attributable to the combined eff ects of these four risk factors surpassed 925 deaths per 100 000 for men in Belarus, Kazakhstan, and Mongolia, but were less than 130 deaths per 100 000 for women and less than 200 for men in some high-income countries including Australia, Canada, France, Japan, the Netherlands, Singapore, South Korea, and Spain. Interpretation The salient features of the cardiometabolic disease and risk factor epidemic at the beginning of the 21st century are high blood pressure and an increasing eff ect of obesity and diabetes. The mortality burden of cardiometabolic risk factors has shifted from high-income to low-income and middle-income countries. Lowering cardiometabolic risks through dietary, behavioural, and pharmacological interventions should be a part of the globalresponse to non-communicable diseases