Analysing Cultural Impacts of Compouter-Mediated Communication in Organisations

In our research in progress, we study how CMC affects culture in office life. By culture we mean here our way of life in general and thus our way of working in work places. We will investigate impacts of CMC on the way we work in offices. In the next section we will explain the meaning of culture used in this research in detail and present evaluation framing (Stamper, 1988) as a conceptual framework

Business model design for sustainable society: Therapy for the consumerist mindset

We address the problem of unsustainable business in the consumerist society with a reframing of the purpose of business, in recognition of the power of higher purpose for the company and contribution to society as the primary stakeholder. In this, the business model operated is crucial, but is generally under-invested, both conceptually unclear and usually more implicit than explicit, and thus lacking in guiding influence on the way a company performs. Despite the apparent significance of why and how a business operates, business model design is only in its infancy. A framework for business model design is outlined. We conclude with a discussion and proposed research agenda

Support: Can it be a value creation strategy for positive marketing?

In pursuit of improving people's wellbeing and engaging in positive marketing, this paper addresses the application of Vickers' Appreciation System to deepen our understanding of how people comprehend their environment and respond to improve their situation. The paper highlights how companies can collaboratively engage in people's appreciation and support them in fulfilling their needs

Consuming identity : the case of Scotland

The paper examines national identity in Scotland. The research explores how consumers perceive the symbols used to represent Scotland, how these symbols relate to their perceptions of contemporary Scottish identity and their responses to the use of these symbols to promote Scotland and Scottishness. A series of in-depth interviews revealed that national identity in Scotland was seen to be multidimensional. Activities associated with art and culture, as opposed to business and industry, were identified as primary characteristics of contemporary Scotland. The traditional symbols of Scottish identity (e.g. tartan and whiskey) remain dominant signifiers, however, and the problems of this are discussed

Public Discourse as Information System: the Use of SSM to Facilitate ‘Healthier’ Stakeholder Discourse

This paper explores dialogue between the diverse stakeholders affected by the introduction of the BioFuels Sales Obligation policy in New Zealand. The research will use ‘rich pictures’ within the framework of Soft Systems Methodology (SSM) to evaluate the extent to which such abstract visualization might facilitate the communication of different viewpoints. It will examine whether the act of representation might encourage individuals, organizations and interest groups to reflect upon their beliefs and assumptions thereby contributing to a healthy discourse around the subject of New Zealand biofuels

Theorizing about resource integration through service-dominant logic

Resource integration, as it relates to value creation, has recently been a key aspect of the discussions about service-dominant (S-D) logic. However, the majority of research pays relatively little explicit attention to the process of theorizing and the epistomological and ontological assumptions upon which the theorizing process is based. This article addresses these issues. The processes that relate to theorizing and developing strong theory are discussed. We then examine how to conceptualize ‘resources’ and ‘resource integration’ following differing ontological and epistemological assumptions that guide the theorizing process. Research recommendations to help navigate through the finer details underlying the theorizing process and to advance a general theory of resource integration are developed

VEGF-A165b is an endogenous neuroprotective splice isoform of vascular endothelial growth factor A in vivo and in vitro

Vascular endothelial growth factor (VEGF) A is generated as two isoform families by alternative RNA splicing, represented by VEGF-A165a and VEGF-A165b. These isoforms have opposing actions on vascular permeability, angiogenesis, and vasodilatation. The proangiogenic VEGF-A165a isoform is neuroprotective in hippocampal, dorsal root ganglia, and retinal neurons, but its propermeability, vasodilatatory, and angiogenic properties limit its therapeutic usefulness. In contrast, a neuroprotective effect of endogenous VEGF-A165b on neurons would be advantageous for neurodegenerative pathologies. Endogenous expression of human and rat VEGF-A165b was detected in hippocampal and cortical neurons. VEGF-A165b formed a significant proportion of total VEGF-A in rat brain. Recombinant human VEGF-A165b exerted neuroprotective effects in response to multiple insults, including glutamatergic excitotoxicity in hippocampal neurons, chemotherapy-induced cytotoxicity of dorsal root ganglion neurons, and retinal ganglion cells (RGCs) in rat retinal ischemia-reperfusion injury in vivo. Neuroprotection was dependent on VEGFR2 and MEK1/2 activation but not on p38 or phosphatidylinositol 3-kinase activation. Recombinant human VEGF-A165b is a neuroprotective agent that effectively protects both peripheral and central neurons in vivo and in vitro through VEGFR2, MEK1/2, and inhibition of caspase-3 induction. VEGF-A165b may be therapeutically useful for pathologies that involve neuronal damage, including hippocampal neurodegeneration, glaucoma diabetic retinopathy, and peripheral neuropathy. The endogenous nature of VEGF-A165b expression suggests that non-isoform-specific inhibition of VEGF-A (for antiangiogenic reasons) may be damaging to retinal and sensory neurons

Cues adopted by consumers in examining corporate website favorability: an empirical study of financial institutions in the UK and Russia

The purpose of this paper is to explore, reconcile and depict corporate website favorability (CWF), its antecedents and consequences in the financial setting in the UK and Russia context. To achieve the goals of this study, the research adopted a mixed method research design by using a survey, which is supported by insights from in-depth interviews and focus group discussions. Exploratory factor analysis (EFA), confirmatory factor analysis (CFA) and Structural equation modeling (SEM) were applied to gain insight into the various influences and relationships. The paper develops and empirically validates the framework of CWF antecedents and consequences. The paper indicates essential guidance for cross-functional managers and designers regarding the integrated and holistic utilization of building favorable corporate websites as part of the corporate identity management. The paper adds to the understanding of CWF and discusses the antecedents of CWF by drawing upon the existing literature. Furthermore, it offers possible consequences of CWF and provides a framework for future testing