409 research outputs found
Chiral Lagrangians at finite density
The effective SU(2) chiral Lagrangian with external sources is given in the
presence of non-vanishing nucleon densities by calculating the in-medium
contributions of the chiral pion-nucleon Lagrangian. As a by product, a
relativistic quantum field theory for Fermi many-particle systems at zero
temperature is directly derived from relativistic quantum field theory with
functional methods.Comment: 6 Pages, 3 figures, REVTeX. Extended version. Explicit Feynman rules
are give
Propiconazole is an activator of AHR and causes concentration additive effects with an established AHR ligand
Consumers are exposed to pesticide residues and other food contaminants via the diet. Both can exert adverse effects on different target organs via the activation of nuclear receptor pathways. Hepatotoxic effects of the widely used triazole fungicide propiconazole (Pi) are generally attributed to the activation of the constitutive androstane receptor (CAR) or the pregnane X receptor (PXR). We now investigated the effects of Pi on the aryl hydrocarbon receptor (AHR) and possible mixture toxicity when Pi is present in combination with BbF, an AHR ligand. In silico docking simulations indicate that Pi can bind to human AHR. Subsequent dual luciferase reporter gene assays in human HepG2 cells showed that Pi activates the AHR in vitro. This concentration-dependent activation was confirmed by real-time RT-PCR analyses of the model AHR target genes CYP1A1 and CYP1A2 in human HepaRG and HepG2 cells. In addition, induction of CYP1A1 protein levels and enzyme activity were recorded. Similarly, increased mRNA expression and enzyme activity of Cyp1a1 and Cyp1a2 was observed in livers of rats treated with Pi for 28 days via the diet. Gene expression analysis in AHR-knockout HepaRG cells showed no induction of CYP1A1 and CYP1A2, whereas gene expression in CAR-, and PXR-knockout cells was induced. Finally, mixture effects of Pi and BbF were analyzed in human cell lines: modeling of concentration\u2013response curves revealed concentration additivity. In conclusion, our results demonstrate that the triazole Pi is an activator of AHR in silico, in vitro and in vivo and causes additive effects with an established AHR ligand
Deuteron Electroweak Disintegration
We study the deuteron electrodisintegration with inclusion of the neutral
currents focusing on the helicity asymmetry of the exclusive cross section in
coplanar geometry. We stress that a measurement of this asymmetry in the quasi
elastic region is of interest for an experimental determination of the weak
form factors of the nucleon, allowing one to obtain the parity violating
electron neutron asymmetry. Numerically, we consider the reaction at low
momentum transfer and discuss the sensitivity of the helicity asymmetry to the
strangeness radius and magnetic moment. The problems coming from the finite
angular acceptance of the spectrometers are also considered.Comment: 30 pages, Latex, 7 eps figures, submitted to Phys.Rev.C e-mail:
[email protected] , [email protected]
Parity violating target asymmetry in electron - proton scattering
We analyze the parity-violating (PV) components of the analyzing power in
elastic electron-proton scattering and discuss their sensitivity to the strange
quark contributions to the proton weak form factors. We point out that the
component of the analyzing power along the momentum transfer is independent of
the electric weak form factor and thus compares favorably with the PV beam
asymmetry for a determination of the strangeness magnetic moment. We also show
that the transverse component could be used for constraining the strangeness
radius. Finally, we argue that a measurement of both components could give
experimental information on the strangeness axial charge.Comment: 24 pages, Latex, 5 eps figures, submitted to Phys.Rev.
A VALUE PLATFORM ANALYSIS PERSPECTIVE ON CUSTOMER ACCESS INFORMATION TECHNOLOGY
Customer access information technologies (CAITs) provide a link between a
firm and its customers. Firms invest in CAITs to reduce costs, increase revenues
and market share, lock in existing customers and capture new ones. These benefits,
however, are notoriously difficult to measure. This paper proposes an evaluative
method for CAlT deployment called value platform analysis, that is based on a
conceptual model drawn from the theory of retail outlet deployment in marketing
science. The model focuses on the impact of CAIT features and environmental
features on transactions generated by the CAIT. Specific econometric models are
developed for deployment. Hypotheses regarding the likely impact of automated
teller machine (ATM) location design choices and environmental features on ATM
transactions are evaluated. The results indicate that there are a number of key
features influencing ATM performance. Two distinct ATM deployment scenarios
emerge: one for servicing a bank's own customers, and another for providing
transaction services for customers for a fee.Information Systems Working Papers Serie
A tetragonal-to-monoclinic phase transition in a ferroelectric perovskite: the structure of PbZr(0.52)Ti(0.48)O3
The perovskite-like ferroelectric system PbZr(1-x)Ti(x)O3 (PZT) has a nearly
vertical morphotropic phase boundary (MPB) around x=0.45-0.50. Recent
synchrotron x-ray powder diffraction measurements by Noheda et al. [Appl. Phys.
Lett. 74, 2059 (1999)] have revealed a new monoclinic phase between the
previously-established tetragonal and rhombohedral regions. In the present work
we describe a Rietveld analysis of the detailed structure of the tetragonal and
monoclinic PZT phases on a sample with x= 0.48 for which the lattice parameters
are respectively: at= 4.044 A, ct= 4.138 A, at 325 K, and am= 5.721 A, bm=
5.708 A, cm= 4.138 A, beta= 90.496 deg., at 20K. In the tetragonal phase the
shifts of the atoms along the polar [001] direction are similar to those in
PbTiO3 but the refinement indicates that there are, in addition, local
disordered shifts of the Pb atoms of ~0.2 A perpendicular to the polar axis..
The monoclinic structure can be viewed as a condensation along one of the
directions of the local displacements present in the tetragonal phase. It
equally well corresponds to a freezing-out of the local displacements along one
of the directions recently reported by Corker et al.[J. Phys. Condens.
Matter 10, 6251 (1998)] for rhombohedral PZT. The monoclinic structure
therefore provides a microscopic picture of the MPB region in which one of the
"locally" monoclinic phases in the "average" rhombohedral or tetragonal
structures freezes out, and thus represents a bridge between these two phases.Comment: REVTeX, 7 figures. Modifications after referee's suggestion: new
figure (figure 5), comments in 2nd para. (Sect.III) and in 2nd & 3rd para.
(Sect. IV-a), in the abstract: "...of ~0.2 A perpendicular to the polar
axis.
Future Directions in Parity Violation: From Quarks to the Cosmos
I discuss the prospects for future studies of parity-violating (PV)
interactions at low energies and the insights they might provide about open
questions in the Standard Model as well as physics that lies beyond it. I cover
four types of parity-violating observables: PV electron scattering; PV hadronic
interactions; PV correlations in weak decays; and searches for the permanent
electric dipole moments of quantum systems.Comment: Talk given at PAVI 06 workshop on parity-violating interactions,
Milos, Greece (May, 2006); 10 page
Strong evidences of hadron acceleration in Tycho's Supernova Remnant
Very recent gamma-ray observations of G120.1+1.4 (Tycho's) supernova remnant
(SNR) by Fermi-LAT and VERITAS provided new fundamental pieces of information
for understanding particle acceleration and non-thermal emission in SNRs. We
want to outline a coherent description of Tycho's properties in terms of SNR
evolution, shock hydrodynamics and multi-wavelength emission by accounting for
particle acceleration at the forward shock via first order Fermi mechanism. We
adopt here a quick and reliable semi-analytical approach to non-linear
diffusive shock acceleration which includes magnetic field amplification due to
resonant streaming instability and the dynamical backreaction on the shock of
both cosmic rays (CRs) and self-generated magnetic turbulence. We find that
Tycho's forward shock is accelerating protons up to at least 500 TeV,
channelling into CRs about the 10 per cent of its kinetic energy. Moreover, the
CR-induced streaming instability is consistent with all the observational
evidences indicating a very efficient magnetic field amplification (up to ~300
micro Gauss). In such a strong magnetic field the velocity of the Alfv\'en
waves scattering CRs in the upstream is expected to be enhanced and to make
accelerated particles feel an effective compression factor lower than 4, in
turn leading to an energy spectrum steeper than the standard prediction
{\propto} E^-2. This latter effect is crucial to explain the GeV-to-TeV
gamma-ray spectrum as due to the decay of neutral pions produced in nuclear
collisions between accelerated nuclei and the background gas. The
self-consistency of such an hadronic scenario, along with the fact that the
concurrent leptonic mechanism cannot reproduce both the shape and the
normalization of the detected the gamma-ray emission, represents the first
clear and direct radiative evidence that hadron acceleration occurs efficiently
in young Galactic SNRs.Comment: Minor changes. Accepted for publication in Astronomy & Astrophysic
Search for a W' boson decaying to a bottom quark and a top quark in pp collisions at sqrt(s) = 7 TeV
Results are presented from a search for a W' boson using a dataset
corresponding to 5.0 inverse femtobarns of integrated luminosity collected
during 2011 by the CMS experiment at the LHC in pp collisions at sqrt(s)=7 TeV.
The W' boson is modeled as a heavy W boson, but different scenarios for the
couplings to fermions are considered, involving both left-handed and
right-handed chiral projections of the fermions, as well as an arbitrary
mixture of the two. The search is performed in the decay channel W' to t b,
leading to a final state signature with a single lepton (e, mu), missing
transverse energy, and jets, at least one of which is tagged as a b-jet. A W'
boson that couples to fermions with the same coupling constant as the W, but to
the right-handed rather than left-handed chiral projections, is excluded for
masses below 1.85 TeV at the 95% confidence level. For the first time using LHC
data, constraints on the W' gauge coupling for a set of left- and right-handed
coupling combinations have been placed. These results represent a significant
improvement over previously published limits.Comment: Submitted to Physics Letters B. Replaced with version publishe
Search for the standard model Higgs boson decaying into two photons in pp collisions at sqrt(s)=7 TeV
A search for a Higgs boson decaying into two photons is described. The
analysis is performed using a dataset recorded by the CMS experiment at the LHC
from pp collisions at a centre-of-mass energy of 7 TeV, which corresponds to an
integrated luminosity of 4.8 inverse femtobarns. Limits are set on the cross
section of the standard model Higgs boson decaying to two photons. The expected
exclusion limit at 95% confidence level is between 1.4 and 2.4 times the
standard model cross section in the mass range between 110 and 150 GeV. The
analysis of the data excludes, at 95% confidence level, the standard model
Higgs boson decaying into two photons in the mass range 128 to 132 GeV. The
largest excess of events above the expected standard model background is
observed for a Higgs boson mass hypothesis of 124 GeV with a local significance
of 3.1 sigma. The global significance of observing an excess with a local
significance greater than 3.1 sigma anywhere in the search range 110-150 GeV is
estimated to be 1.8 sigma. More data are required to ascertain the origin of
this excess.Comment: Submitted to Physics Letters
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