Foaming characteristics of β-lactoglobulin as affected by enzymatic hydrolysis and polysaccharide addition: Relationships with the bulk and interfacial properties

The objective of this work was to study the effect of enzymatic hydrolysis and polysaccharide addition on the foaming characteristics of β-lactoglobulin (β-LG). Enzymatic treatment was performed in the hydrolysis degree (HD) range of 0.0–5.0% using bovine α-chymotrypsin II immobilized on agarose microbeads. Anionic non-surface active polysaccharides (PS), sodium alginate (SA) and λ-carrageenan (λ-C) were studied in the concentration range of 0.0–0.5 wt.%. Foaming characteristics were determined by conductimetric and optical methods and were linked to protein diffusion kinetics, film mechanical properties and biopolymer molecular dynamics in solution. Experiments were performed at constant temperature (20 °C), pH 7 and ionic strength 0.05 M. Limited hydrolysis improved the formation and stability of β-LG foam possibly due to an increased protein diffusion rate and film dilatational elasticity. Furthermore, PS addition caused different effects on β-LG foaming characteristics depending on the PS type, their relative concentration and extent of enzymatic treatment (HD). Diffusion rate and interfacial rheological behavior of mixed systems could exert a decisive role in foaming characteristics of β-LG and its hydrolysates in close connection with biopolymer interactions in solution, e.g., macromolecule repulsion, protein segregation/aggregation and soluble complexes formation.Fil: Perez, Adrián Alejandro. Universidad Nacional del Litoral. Facultad de Ingeniería Química. Instituto de Tecnología de los Alimentos; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe; ArgentinaFil: Carrera Sánchez, Cecilio. Universidad de Sevilla; EspañaFil: Rodríguez Patino, Juan M.. Universidad de Sevilla; EspañaFil: Rubiolo, Amelia Catalina. Universidad Nacional del Litoral. Facultad de Ingeniería Química. Instituto de Tecnología de los Alimentos; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe; ArgentinaFil: Santiago, Liliana Gabriela. Universidad Nacional del Litoral. Facultad de Ingeniería Química. Instituto de Tecnología de los Alimentos; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe; Argentin

Uso de las tecnologías de la información y las comunicaciones en la carrera de Enfermería

Introduction: new technologies favor the scientific and technical development of society, which is why these must be assimilated into the teaching-learning process by nursing care students.Objective: to characterize the use of information and communication technologies by students of the Degree in Nursing at Pinar del Río University of Medical Sciences between January and March 2018.Methods: observational, descriptive, and cross-sectional study of second-academic year students of bachelor degree in nursing care. Theoretical and empirical methods were used. Statistical measures were applied as absolute frequency and relative percentage.Results: it was found that 23.5 % did not have access to any personal computers. Half of the target group said they own a mobile phone with Android or iOS operating system; 59.3 % of the students did not use the institutional Internet network, 23.5 % used it for teaching purposes; 76.5 % reported using lectures and complementary computerized materials for the individual study; 46. 9% used both computers and conventional aids; 12 % of the students expressed they do not find computer-aided learning useful.Conclusions: it was found the application of Information and Communication Technologies in the teaching-learning process is very useful, having a high access; where Smartphone is the most used; there is a poor use of Internet network for the teaching-learning and research processes. Computer-aided learning is widely used to the individual study.Introducción: las nuevas tecnologías favorecen el desarrollo científico técnico de la sociedad, por lo cual se deben asimilar en el proceso enseñanza aprendizaje por los estudiantes de la carrera.Objetivo: caracterizar el uso de las tecnologías de la información y las comunicaciones por los estudiantes de la carrera Licenciatura en Enfermería de la Universidad de Ciencias Médicas de Pinar del Río entre enero y marzo de 2018.Métodos: estudio observacional, descriptivo, y transversal en los estudiantes de segundo año de licenciatura en Enfermería. Se emplearon métodos teóricos y empíricos. Se aplicaron medidas estadísticas como frecuencia absoluta y relativa porcentual.Resultados: se encontró que el 23,5 % no poseía acceso a ningún medio informático. La mitad del universo de estudio expresó poseer un teléfono móvil con sistema operativo Android o iOS. El 59,3 % de los estudiantes no empleaban la conexión institucional a Internet, el 23,5 % la emplea para fines docentes. El 76,5 % refirió utilizar las conferencias y materiales complementarios digitalizados para el estudio; el 46,9 % empleó tanto los medios digitales, como los convencionales. El 12 % de los estudiantes expresó que no encuentran útiles los medios informáticos para el aprendizaje.Conclusiones: Se encontró utilidad en el uso de las Tecnologías de la Información y la Comunicación en el proceso docente, los cuales poseen con elevado acceso; donde los teléfonos inteligentes, son las más empleadas, existiendo una pobre utilización del Internet para el proceso docente e investigativo. Los materiales en soporte digital son ampliamente empleados para el estudio.

Application of information and communication technologies in nursing care studies

Introduction: new technologies favor the scientific and technical development of society, which is why these must be assimilated into the teaching-learning process by nursing care students. Objective: to characterize the use of information and communication technologies by students of the Degree in Nursing at Pinar del Río University of Medical Sciences between January and March 2018. Methods: observational, descriptive, and cross-sectional study of second-academic year students of bachelor degree in nursing care. Theoretical and empirical methods were used. Statistical measures were applied as absolute frequency and relative percentage. Results: it was found that 23.5 % did not have access to any personal computers. Half of the target group said they own a mobile phone with Android or iOS operating system; 59.3 % of the students did not use the institutional Internet network, 23.5 % used it for teaching purposes; 76.5 % reported using lectures and complementary computerized materials for the individual study; 46. 9% used both computers and conventional aids; 12 % of the students expressed they do not find computer-aided learning useful. Conclusions: it was found the application of Information and Communication Technologies in the teaching-learning process is very useful, having a high access; where Smartphone is the most used; there is a poor use of Internet network for the teaching-learning and research processes. Computer-aided learning is widely used to the individual study

Efecto del agua saborizada sobre la morfología y la composición química de la microestructura del esmalte dental humano in vitro

El contenido mineral del esmalte está representado por el fosfato decacálcico hidroxiapatita. Se ha demostrado que la dureza adamantina decrece desde la superficie libre a la conexión amelodentinaria en el esmalte sano. Además, algunos elementos varían en su concentración (g%) desde la superficie externa hacia el límite amelodentinario.Facultad de Odontologí

Natural History of MYH7-Related Dilated Cardiomyopathy

BACKGROUND Variants in myosin heavy chain 7 (MYH7) are responsible for disease in 1% to 5% of patients with dilated cardiomyopathy (DCM); however, the clinical characteristics and natural history of MYH7-related DCM are poorly described. OBJECTIVES We sought to determine the phenotype and prognosis of MYH7-related DCM. We also evaluated the influence of variant location on phenotypic expression. METHODS We studied clinical data from 147 individuals with DCM-causing MYH7 variants (47.6% female; 35.6 +/- 19.2 years) recruited from 29 international centers. RESULTS At initial evaluation, 106 (72.1%) patients had DCM (left ventricular ejection fraction: 34.5% +/- 11.7%). Median follow-up was 4.5 years (IQR: 1.7-8.0 years), and 23.7% of carriers who were initially phenotype-negative developed DCM. Phenotypic expression by 40 and 60 years was 46% and 88%, respectively, with 18 patients (16%) first diagnosed at <18 years of age. Thirty-six percent of patients with DCM met imaging criteria for LV noncompaction. During follow-up, 28% showed left ventricular reverse remodeling. Incidence of adverse cardiac events among patients with DCM at 5 years was 11.6%, with 5 (4.6%) deaths caused by end-stage heart failure (ESHF) and 5 patients (4.6%) requiring heart transplantation. The major ventricular arrhythmia rate was low (1.0% and 2.1% at 5 years in patients with DCM and in those with LVEF of <= 35%, respectively). ESHF and major ventricular arrhythmia were significantly lower compared with LMNA-related DCM and similar to DCM caused by TTN truncating variants. CONCLUSIONS MYH7-related DCM is characterized by early age of onset, high phenotypic expression, low left ventricular reverse remodeling, and frequent progression to ESHF. Heart failure complications predominate over ventricular arrhythmias, which are rare. (C) 2022 The Authors. Published by Elsevier on behalf of the American College of Cardiology Foundation

Optimasi Portofolio Resiko Menggunakan Model Markowitz MVO Dikaitkan dengan Keterbatasan Manusia dalam Memprediksi Masa Depan dalam Perspektif Al-Qur`an

Risk portfolio on modern finance has become increasingly technical, requiring the use of sophisticated mathematical tools in both research and practice. Since companies cannot insure themselves completely against risk, as human incompetence in predicting the future precisely that written in Al-Quran surah Luqman verse 34, they have to manage it to yield an optimal portfolio. The objective here is to minimize the variance among all portfolios, or alternatively, to maximize expected return among all portfolios that has at least a certain expected return. Furthermore, this study focuses on optimizing risk portfolio so called Markowitz MVO (Mean-Variance Optimization). Some theoretical frameworks for analysis are arithmetic mean, geometric mean, variance, covariance, linear programming, and quadratic programming. Moreover, finding a minimum variance portfolio produces a convex quadratic programming, that is minimizing the objective function ðð¥with constraintsð ð 𥠥 ðandð´ð¥ = ð. The outcome of this research is the solution of optimal risk portofolio in some investments that could be finished smoothly using MATLAB R2007b software together with its graphic analysis

Measurement of the Splitting Function in &ITpp &ITand Pb-Pb Collisions at root&ITsNN&IT=5.02 TeV

Data from heavy ion collisions suggest that the evolution of a parton shower is modified by interactions with the color charges in the dense partonic medium created in these collisions, but it is not known where in the shower evolution the modifications occur. The momentum ratio of the two leading partons, resolved as subjets, provides information about the parton shower evolution. This substructure observable, known as the splitting function, reflects the process of a parton splitting into two other partons and has been measured for jets with transverse momentum between 140 and 500 GeV, in pp and PbPb collisions at a center-of-mass energy of 5.02 TeV per nucleon pair. In central PbPb collisions, the splitting function indicates a more unbalanced momentum ratio, compared to peripheral PbPb and pp collisions.. The measurements are compared to various predictions from event generators and analytical calculations.Peer reviewe

Search for supersymmetry in events with one lepton and multiple jets in proton-proton collisions at root s=13 TeV

Peer reviewe

Measurement of the top quark mass using charged particles in pp collisions at root s=8 TeV

Peer reviewe