49 research outputs found

    Library Publishing Toolkit

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    Both public and academic libraries are invested in the creation and distribution of information and digital content. They have morphed from keepers of content into content creators and curators, and seek best practices and efficient workflows with emerging publishing platforms and services. The Library Publishing Toolkit looks at the broad and varied landscape of library publishing through discussions, case studies, and shared resources. From supporting writers and authors in the public library setting to hosting open access journals and books, this collection examines opportunities for libraries to leverage their position and resources to create and provide access to content.The Library Publishing Toolkit is a project funded partially by Bibliographic Databases and Interlibrary Resources Sharing Program funds which are administered and supported by the Rochester Regional Library Council. The toolkit is a united effort between Milne Library at SUNY Geneseo and the Monroe County Library System to identify trends in library publishing, seek out best practices to implement and support such programs, and share the best tools and resources. Our goals include to: Develop strategies libraries can use to identify types of publishing services and content that can be created and curated by libraries. Assess trends in digital content creation and publishing that can be useful in libraries and suggesting potential future projects. Identify efficient workflows for distributing content for free online and with potential for some cost-recovery in print on demand markets. A list of chapters is available in the full record.https://knightscholar.geneseo.edu/idsproject-press/1002/thumbnail.jp

    Effects of rare kidney diseases on kidney failure: a longitudinal analysis of the UK National Registry of Rare Kidney Diseases (RaDaR) cohort.

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    BACKGROUND: Individuals with rare kidney diseases account for 5-10% of people with chronic kidney disease, but constitute more than 25% of patients receiving kidney replacement therapy. The National Registry of Rare Kidney Diseases (RaDaR) gathers longitudinal data from patients with these conditions, which we used to study disease progression and outcomes of death and kidney failure. METHODS: People aged 0-96 years living with 28 types of rare kidney diseases were recruited from 108 UK renal care facilities. The primary outcomes were cumulative incidence of mortality and kidney failure in individuals with rare kidney diseases, which were calculated and compared with that of unselected patients with chronic kidney disease. Cumulative incidence and Kaplan-Meier survival estimates were calculated for the following outcomes: median age at kidney failure; median age at death; time from start of dialysis to death; and time from diagnosis to estimated glomerular filtration rate (eGFR) thresholds, allowing calculation of time from last eGFR of 75 mL/min per 1·73 m2 or more to first eGFR of less than 30 mL/min per 1·73 m2 (the therapeutic trial window). FINDINGS: Between Jan 18, 2010, and July 25, 2022, 27 285 participants were recruited to RaDaR. Median follow-up time from diagnosis was 9·6 years (IQR 5·9-16·7). RaDaR participants had significantly higher 5-year cumulative incidence of kidney failure than 2·81 million UK patients with all-cause chronic kidney disease (28% vs 1%; p<0·0001), but better survival rates (standardised mortality ratio 0·42 [95% CI 0·32-0·52]; p<0·0001). Median age at kidney failure, median age at death, time from start of dialysis to death, time from diagnosis to eGFR thresholds, and therapeutic trial window all varied substantially between rare diseases. INTERPRETATION: Patients with rare kidney diseases differ from the general population of individuals with chronic kidney disease: they have higher 5-year rates of kidney failure but higher survival than other patients with chronic kidney disease stages 3-5, and so are over-represented in the cohort of patients requiring kidney replacement therapy. Addressing unmet therapeutic need for patients with rare kidney diseases could have a large beneficial effect on long-term kidney replacement therapy demand. FUNDING: RaDaR is funded by the Medical Research Council, Kidney Research UK, Kidney Care UK, and the Polycystic Kidney Disease Charity

    The genetic architecture of the human cerebral cortex

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    The cerebral cortex underlies our complex cognitive capabilities, yet little is known about the specific genetic loci that influence human cortical structure. To identify genetic variants that affect cortical structure, we conducted a genome-wide association meta-analysis of brain magnetic resonance imaging data from 51,665 individuals. We analyzed the surface area and average thickness of the whole cortex and 34 regions with known functional specializations. We identified 199 significant loci and found significant enrichment for loci influencing total surface area within regulatory elements that are active during prenatal cortical development, supporting the radial unit hypothesis. Loci that affect regional surface area cluster near genes in Wnt signaling pathways, which influence progenitor expansion and areal identity. Variation in cortical structure is genetically correlated with cognitive function, Parkinson's disease, insomnia, depression, neuroticism, and attention deficit hyperactivity disorder

    CEO succession and the CEO’s commitment to the status quo

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    Chief executive officer (CEO) commitment to the status quo (CSQ) is expected to play an important role in any firm’s strategic adaptation. CSQ is used often as an explanation for strategic change occurring after CEO succession: new CEOs are expected to reveal a lower CSQ than established CEOs. Although widely accepted in the literature, this relationship remains imputed but unobserved. We address this research gap and analyze whether new CEOs reveal lower CSQ than established CEOs. By analyzing the letters to the shareholders of German HDAX firms, we find empirical support for our hypothesis of a lower CSQ of newly appointed CEOs compared to established CEOs. However, our detailed analyses provide a differentiated picture. We find support for a lower CSQ of successors after a forced CEO turnover compared to successors after a voluntary turnover, which indicates an influence of the mandate for change on the CEO’s CSQ. However, against the widespread assumption, we do not find support for a lower CSQ of outside successors compared to inside successors, which calls for deeper analyses of the insiderness of new CEOs. Further, our supplementary analyses propose a revised tenure effect: the widely assumed relationship of an increase in CSQ when CEO tenure increases might be driven mainly by the event of CEO succession and may not universally and continuously increase over time, pointing to a “window of opportunity” to initiate strategic change shortly after the succession event. By analyzing the relationship between CEO succession and CEO CSQ, our results contribute to the CSQ literature and provide fruitful impulses for the CEO succession literature

    Reducing the environmental impact of surgery on a global scale: systematic review and co-prioritization with healthcare workers in 132 countries

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    Abstract Background Healthcare cannot achieve net-zero carbon without addressing operating theatres. The aim of this study was to prioritize feasible interventions to reduce the environmental impact of operating theatres. Methods This study adopted a four-phase Delphi consensus co-prioritization methodology. In phase 1, a systematic review of published interventions and global consultation of perioperative healthcare professionals were used to longlist interventions. In phase 2, iterative thematic analysis consolidated comparable interventions into a shortlist. In phase 3, the shortlist was co-prioritized based on patient and clinician views on acceptability, feasibility, and safety. In phase 4, ranked lists of interventions were presented by their relevance to high-income countries and low–middle-income countries. Results In phase 1, 43 interventions were identified, which had low uptake in practice according to 3042 professionals globally. In phase 2, a shortlist of 15 intervention domains was generated. In phase 3, interventions were deemed acceptable for more than 90 per cent of patients except for reducing general anaesthesia (84 per cent) and re-sterilization of ‘single-use’ consumables (86 per cent). In phase 4, the top three shortlisted interventions for high-income countries were: introducing recycling; reducing use of anaesthetic gases; and appropriate clinical waste processing. In phase 4, the top three shortlisted interventions for low–middle-income countries were: introducing reusable surgical devices; reducing use of consumables; and reducing the use of general anaesthesia. Conclusion This is a step toward environmentally sustainable operating environments with actionable interventions applicable to both high– and low–middle–income countries

    Si usted tiene la mas minima duda" ... escoja un artesano

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    En el curso de varios años, he observado desde adentro una empresa internacional de servicios financieros con activos que alcanzan decenas de miles de millones de dólares y sucursales en varios continentes. Después de haber asistido a innumerables sesiones ordinarias y extraordinarias de comités y de consejos, me pareció claramente que uno encontraba tres grandes tipos de personas -el artista, el tecnócrata y el artesano- entre los quince jefes de dirección del grupo y de sus grandes divisiones. Cada uno de los tres tipos de dirigentes hablaba un lenguaje diferente y tenía intereses y prioridades variadas. El uno quería que la empresa "conquistara" el mundo, al menos vastas partes del mundo; el otro "perfeccionara" que ya hacia; y el tercero, que pusiera a sus "sistemas" y generara utilidades. Los dos primeros grupos deseaban igualmente alcanza utilidades, pero su concepción la manera de realizar difería enormemente de la del tercero

    The drama of leadership: artists, craftsmen, and technocrats and the power struggle that shapes organizations and societies

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    In The Drama of Leadership, Patricia Pitcher shares her findings and, in the process, explodes a number of popular myths about leadership, including the one that leadership and vision are qualities that can be taught in management seminars. She refutes the common belief that leaders are in short supply and proves that the corporate talent pool abounds with potential leaders whose talents either go unrecognized or are tragically undervalued. And she explains why, at a time when vision, innovation, humanity, and passion are so desperately needed, so many companies cast in leadership roles people who possess none of these qualities, and who distrust anyone who does

    Artistes, artisans et technocrates dans nos organisations : rêves, réalités et illusions du leadership /

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    2e éd. enrichieBibliogr.: p. 265Notes (part. bibliogr.) au bas des p.Artists, craftsmen, and technocrat

    The formation of smooth, defect-free, stoichiometric silicon carbide films from a polymeric precursor

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    Silicon carbide (SiC) materials, which are used in a variety of applications, are often produced using powder processing, sintering or bulk crystal growing techniques. The formation of silicon carbide films or shaped products, via these methods, is often extremely difficult and/or requires high temperatures. Here we report the synthesis and characterization of a polymeric precursor, Polymethylsilyne (PMSy), and it subsequent conversion to beta-SiC. The polymer is simple to synthesize and is easily manipulated in air. The ceramic produced from PMSy is extremely pure, stoichiometric SiC and is produced in high yields (up to 85%). The ceramic films that can be produced from PMSy on a variety of substrates, from ceramics to metals, are again stoichiometric SiC and are smooth, continuous and defect free; possibly enabling the use of these films in electronic applications

    Fisheries Centre research reports, Vol. 12, no. 2

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    Director’s Foreword. SUMMARY. INTRODUCTION. Rapfish Software Development Requirements. RAPFISH EXCEL VBA SOFTWARE DESIGN DESCRIPTION. Software Architecture. User Interface Form: Enter Data, Run Rapfish Analysis and Options. Rapfish Analysis Procedure with the User Interface Form.VBA Subroutines. Multi-Dimensional Scaling Using ALSCAL Fortran DLL. RAPFISH INSTALLATION AND USE. Installation Description. Software Installation Steps. Analyzing Your Own Fisheries Scoring Data. How to Edit the Rapfish Add-In for Further Development. RAPFISH: WHAT DOES IT ALL MEAN? Interpretation. Rapfish Error and Variability. Sustainability ‘Calibration’. Dominant Attributes. FUTURE RAPFISH DEVELOPMENT. MULTIPLICATIVE UTILITY: RAPFISH-M. REFERENCES. ANNEXES. Annex 1: Published Papers Using Rapfish. Annex 2: The ALSCAL FORTRAN DLL. Annex 3: VBA Code for Rapfish Excel Add-in. Annex 4: VBA routine to label points in Excel x-y graph.Fisheries Centre (FC)UnreviewedFacultyResearcherGraduat
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