Unifying S\o rensen-M\o lmer gate and Milburn gate with an optomechanical example

S\o rensen-M\o lmer gate and Milburn gate are two geometric phase gates, generating nonlinear self-interaction of a target mode via its interaction with an auxiliary mechanical mode, in the continuous and pulsed interaction regime, respectively. In this paper, we aim at unifying the two gates by demonstrating that S\o rensen-M\o lmer gate is the continuous limit of Milburn gate, emphasising the geometrical interpretation in the mechanical phase space. We explicitly consider imperfect gate parameters, focusing on relative errors in time for S\o rensen-M\o lmer gate and in phase angle increment for Milburn gate. We find that, although the purities of the final states increase for the two gates upon reducing the interaction strength together with traversing the mechanical phase space multiple times, the fidelities behave differently. We point out that, the difference exists because the interaction strength depends on the relative error when taking the continuous limit from the pulsed regime, thereby unifying the mathematical framework of the two gates. We demonstrate this unification in the example of an optomechanical system, where mechanical dissipation is also considered. We highlight that, the unified framework facilitates the new method of deriving the dynamics of the continuous interaction regime without solving differential equations.Comment: 13 pages including Appendix, 8 figures, accepted by Physical Review

Cosmological constraints from the capture of non-Gaussianity in Weak Lensing data

Weak gravitational lensing has become a common tool to constrain the cosmological model. The majority of the methods to derive constraints on cosmological parameters use second-order statistics of the cosmic shear. Despite their success, second-order statistics are not optimal and degeneracies between some parameters remain. Tighter constraints can be obtained if second-order statistics are combined with a statistic that is efficient to capture non-Gaussianity. In this paper, we search for such a statistical tool and we show that there is additional information to be extracted from statistical analysis of the convergence maps beyond what can be obtained from statistical analysis of the shear field. For this purpose, we have carried out a large number of cosmological simulations along the {\sigma}8-{\Omega}m degeneracy, and we have considered three different statistics commonly used for non-Gaussian features characterization: skewness, kurtosis and peak count. To be able to investigate non-Gaussianity directly in the shear field we have used the aperture mass definition of these three statistics for different scales. Then, the results have been compared with the results obtained with the same statistics estimated in the convergence maps at the same scales. First, we show that shear statistics give similar constraints to those given by convergence statistics, if the same scale is considered. In addition, we find that the peak count statistic is the best to capture non-Gaussianities in the weak lensing field and to break the {\sigma}8-{\Omega}m degeneracy. We show that this statistical analysis should be conducted in the convergence maps: first, because there exist fast algorithms to compute the convergence map for different scales, and secondly because it offers the opportunity to denoise the reconstructed convergence map, which improves non-Gaussian features extraction.Comment: Accepted for publication in MNRAS (11 pages, 5 figures, 9 tables

Household economic hardship as a moderator of the associations between maternal spanking and child externalizing behavior problems.

Background: Spanking is associated with detrimental outcomes for young children. Research shows that spanking is more commonly used in low-income households. Objective: To examine whether economic hardship, measured by household income-to-poverty ratio at the time of the child’s birth, moderated the longitudinal associations between maternal spanking and child externalizing behavior problems during the first nine years of childhood. Participants and setting: Mother-child pairs (N = 4,149) from a cohort study of urban families in 20 US cities. Methods: Cross-lagged path models examined associations between maternal spanking and ex- ternalizing behavior when children were between the ages of 1 and 9. Multigroup analyses ex- amined whether income-to-poverty ratio moderated these associations. Results: Bivariate analyses showed that income-to-poverty ratio was associated with child ex- ternalizing behavior problems at each time point; income-to-poverty ratio was associated with maternal spanking at age 3 only. Longitudinal path model results indicated that, for low- and middle-income groups, maternal spanking at each age had significant associations with child externalizing behavior at each subsequent age. For the high-income group, maternal spanking at age 1 and age 3 had significant associations with child externalizing behavior at each subsequent age; however, spanking at age 5 was not associated with child externalizing behavior at age 9. Conclusions: Spanking is disadvantageous for children at all income levels, with more persistent effects in low- and middle-income families. For higher-income families, the associations of ma- ternal spanking with child externalizing behavior problems may be attenuated as child age in- creases. Regardless of income level, parents should be advised against spanking.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/163755/1/2020-Lee-Householdeconomichardship.pdfDescription of 2020-Lee-Householdeconomichardship.pdf : Main articl

Attachment style and the association of spanking and child externalizing behavior

OBJECTIVE: To examine whether the longitudinal associations between maternal spanking and child externalizing behavior are moderated by attachment style. METHODS: This study used data from the Fragile Families and Child Wellbeing Study (n = 2211), a large cohort sample of low-income urban families. Multiple-group autoregressive cross-lagged models examined the associations between maternal spanking and child externalizing behavior when children were ages 1, 3, and 5. Moderation by attachment style was examined using structural invariance testing. RESULTS: For children with an insecure mother-child attach- ment style, spanking at age 1 was associated with externalizing behavior at age 3. However, for children with a secure mother- child attachment style, the association between maternal spank- ing at age 1 and child externalizing behavior at age 3 was absent. Attachment style did not moderate the association between maternal spanking at age 3 and externalizing behavior at age 5, suggesting that spanking at age 3 is associated with deleterious outcomes at age 5, regardless of attachment style. CONCLUSIONS: Results suggest that even in the context of a secure attachment style, spanking is associated with adverse outcomes in early childhood. Findings support the American Academy of Pediatrics 2018 policy statement, which encour- ages parents to avoid spanking when disciplining children. Results suggest that children, regardless of attachment style, may benefit from policies and services that promote non-vio- lent forms of discipline.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/163754/1/2020-Ward-Attachmentstyleandtheassociation.pdfDescription of 2020-Ward-Attachmentstyleandtheassociation.pdf : Main articl

Structural Plasticity and Noncovalent Substrate Binding in the GroEL Apical Domain. A study using electrospray ionization mass spectrometry and fluorescence binding studies

Advances in understanding how GroEL binds to non-native proteins are reported. Conformational flexibility in the GroEL apical domain, which could account for the variety of substrates that GroEL binds, is illustrated by comparison of several independent crystallographic structures of apical domain constructs that show conformational plasticity in helices H and I. Additionally, ESI-MS indicates that apical domain constructs have co-populated conformations at neutral pH. To assess the ability of different apical domain conformers to bind co-chaperone and substrate, model peptides corresponding to the mobile loop of GroES and to helix D from rhodanese were studied. Analysis of apical domain-peptide complexes by ESI-MS indicates that only the folded or partially folded apical domain conformations form complexes that survive gas phase conditions. Fluorescence binding studies show that the apical domain can fully bind both peptides independently. No competition for binding was observed, suggesting the peptides have distinct apical domain-binding sites. Blocking the GroES-apical domain-binding site in GroEL rendered the chaperonin inactive in binding GroES and in assisting the folding of denatured rhodanese, but still capable of binding non-native proteins, supporting the conclusion that GroES and substrate proteins have, at least partially, distinct binding sites even in the intact GroEL tetradecamer

Transverse Polarisation of Quarks in Hadrons

We review the present state of knowledge regarding the transverse polarisation (or transversity) distributions of quarks. After some generalities on transverse polarisation, we formally define the transversity distributions within the framework of a classification of all leading-twist distribution functions. We describe the QCD evolution of transversity at leading and next-to-leading order. A comprehensive treatment of non-perturbative calculations of transversity distributions (within the framework of quark models, lattice QCD and QCD sum rules) is presented. The phenomenology of transversity (in particular, in Drell-Yan processes and semi-inclusive leptoproduction) is discussed in some detail. Finally, the prospects for future measurements are outlined.Comment: small changes, references added, as finally published in Physics Report

A double-deletion method to quantifying incremental binding energies in proteins from experiment. Example of a destabilizing hydrogen bonding pair

The contribution of a specific hydrogen bond in apoflavodoxin to protein stability is investigated by combining theory, experiment and simulation. Although hydrogen bonds are major determinants of protein structure and function, their contribution to protein stability is still unclear and widely debated. The best method so far devised to estimate the contribution of side-chain interactions to protein stability is double-mutant-cycle analysis, but the interaction energies so derived are not identical to incremental binding energies (the energies quantifying net contributions of two interacting groups to protein stability). Here we introduce double-deletion analysis of isolated residue pairs as a means to precisely quantify incremental binding. The method is exemplified by studying a surface-exposed hydrogen bond in a model protein (Asp96/Asn128 in apoflavodoxin). Combined substitution of these residues by alanines slightly destabilizes the protein, due to a decrease in hydrophobic surface burial. Subtraction of this effect, however, clearly indicates that the hydrogen-bonded groups in fact destabilize the native conformation. In addition, Molecular Dynamics simulations and classic double-mutant-cycle analysis explain quantitatively that, due to frustration, the hydrogen bond must form in the native structure because, when the two groups get approximated upon folding their binding becomes favorable. We would like to remark two facts: that this is the first time the contribution of a specific hydrogen bond to protein stability has been measured from experiment, and that more hydrogen bonds need to be analyzed in order to draw general conclusions on protein hydrogen bonds energetics. To that end, the double deletion method should be of help.Comment: 41 pages, To appear in Biophysical Journal (in press

Sibling relationships and family functioning in siblings of early adolescents, adolescents and young adults with autism spectrum disorder

The purpose of the study was to investigate how family functioning (defined as the ability that family members hold to manage stressful events, and intimate and social relationships), the degree to which family members feel happy and fulfilled with each other (called family satisfaction), and the demographical characteristics of siblings (age and gender) impacted on sibling relationships. The Circumplex Model of Marital and Family Systems and Behavioral Systems constituted the theoretical frameworks that guided our study. Eighty-six typically developing adolescents and young adults having a sister or a brother with autism spectrum disorder were enrolled. Results indicated that the youngest age group (early adolescents) reported to engage more frequently in negative behaviors with their siblings with ASD than the two older age groups (middle adolescents and young adults). No significant differences were found among the three age groups regarding behaviors derived from attachment, caregiving and affiliative systems. Family satisfaction and age significantly predicted behaviors during sibling interactions. Suggestions on prevention and intervention programs were discussed in order to prevent parentification among typically developing siblings and decrease episodes of quarrels and overt conflicts between brothers and sisters with and without AS

A Bayesian analysis of the associations between neighborhoods, spanking and child externalizing behavior

Background A large body of research has found that corporal punishment is associated with increases in children’s behavior problems. However, questions remain as to whether or not the relationship between corporal punishment and behavior problems is equally true across contexts. Objective To examine the degree to which the effects of corporal punishment are equivalent across neighborhoods. Specifically, is corporal punishment equivalently associated with child behavior problems in neighborhoods that are perceived to be unsafe or disadvantaged, as compared to neighborhoods that are perceived to be less disadvantaged? Participants 2703 participants in the Fragile Families and Child Wellbeing Study. Methods We employed Bayesian regression methods, to examine the association of neighborhood disadvantage, corporal punishment, and their interaction, with child behavior problems. Results Findings suggest that both neighborhood disadvantage (β = 0.070) and parental use of corporal punishment (β = 0.169) had main effect associations with child behavior. However, there was no evidence for an interaction of neighborhood disadvantage and corporal punishment use. Conclusions Both corporal punishment and neighborhood disadvantage were associated with increases in child behavior problems. Corporal punishment appears to be equally deleterious across neighborhood contexts.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/163753/1/2020-GroganKaylor-Abayesiananalysisofassociations.pdfDescription of 2020-GroganKaylor-Abayesiananalysisofassociations.pdf : Main articl

Global perspectives on physical and nonphysical discipline: A Bayesian multilevel analysis

Background and Objective: Sixty countries worldwide have banned the use of physical punishment, yet little is known about the association of physical and nonphysical forms of child discipline with child development in a global context. The objective of this study is to examine whether physical punishment and nonphysical discipline are associated with child socioemotional functioning in a global sample of families from 62 countries and whether country-level normativeness of physical punishment and nonphysical discipline moderated those associations. Methods: Data for this study are from 215,885 families in the fourth and fifth rounds of the United Nations Children’s Fund Multiple Indicator Cluster Surveys. Bayesian multilevel logistic models were used to analyze the associations of physical punishment and nonphysical discipline (i.e., taking away privileges and verbal reasoning) with three different outcomes representing children’s socioemotional functioning: getting along well with other children, aggression, and becoming distracted. Results: The use of physical punishment was not associated with getting along with other children, was associated with increased aggression, and was associated with increases in distraction. Taking away privileges was associated with lower levels of getting along with other children, higher levels of aggression, and higher levels of becoming distracted. Verbal reasoning (i.e., explaining why a behavior was wrong) was associated with higher levels of getting along with other children, higher levels of aggression, and higher levels of becoming distracted. Country-level normativeness moderated some of these associations but in general the direction of effects was consistent. Conclusions: Results suggest that eliminating physical punishment would benefit children across the globe and align with the United Nations Convention on the Rights of the Child, which calls for all children to be free from physical violence. More attention needs to be focused on the associations of nonphysical forms of discipline with child functioning across the globe.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/165323/1/2021 Grogan-Kaylor MICS_IJBD.pdfDescription of 2021 Grogan-Kaylor MICS_IJBD.pdf : Main articl