66 research outputs found

    Measurement of the Strong Coupling alpha s from Four-Jet Observables in e+e- Annihilation

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    Data from e+e- annihilation into hadrons at centre-of-mass energies between 91 GeV and 209 GeV collected with the OPAL detector at LEP, are used to study the four-jet rate as a function of the Durham algorithm resolution parameter ycut. The four-jet rate is compared to next-to-leading order calculations that include the resummation of large logarithms. The strong coupling measured from the four-jet rate is alphas(Mz0)= 0.1182+-0.0003(stat.)+-0.0015(exp.)+-0.0011(had.)+-0.0012(scale)+-0.0013(mass) in agreement with the world average. Next-to-leading order fits to the D-parameter and thrust minor event-shape observables are also performed for the first time. We find consistent results, but with significantly larger theoretical uncertainties.Comment: 25 pages, 15 figures, Submitted to Euro. Phys. J.

    Higher harmonic anisotropic flow measurements of charged particles in Pb-Pb collisions at 2.76 TeV

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    We report on the first measurement of the triangular v3v_3, quadrangular v4v_4, and pentagonal v5v_5 charged particle flow in Pb-Pb collisions at 2.76 TeV measured with the ALICE detector at the CERN Large Hadron Collider. We show that the triangular flow can be described in terms of the initial spatial anisotropy and its fluctuations, which provides strong constraints on its origin. In the most central events, where the elliptic flow v2v_2 and v3v_3 have similar magnitude, a double peaked structure in the two-particle azimuthal correlations is observed, which is often interpreted as a Mach cone response to fast partons. We show that this structure can be naturally explained from the measured anisotropic flow Fourier coefficients.Comment: 10 pages, 4 figures, published version, figures at http://aliceinfo.cern.ch/ArtSubmission/node/387

    International genome-wide meta-analysis identifies new primary biliary cirrhosis risk loci and targetable pathogenic pathways

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    Controversy and consensus on the management of elevated sperm DNA fragmentation in male infertility: A global survey, current guidelines, and expert recommendations

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    Purpose Sperm DNA fragmentation (SDF) has been associated with male infertility and poor outcomes of assisted reproductive technology (ART). The purpose of this study was to investigate global practices related to the management of elevated SDF in infertile men, summarize the relevant professional society recommendations, and provide expert recommendations for managing this condition. Materials and Methods An online global survey on clinical practices related to SDF was disseminated to reproductive clinicians, according to the CHERRIES checklist criteria. Management protocols for various conditions associated with SDF were captured and compared to the relevant recommendations in professional society guidelines and the appropriate available evidence. Expert recommendations and consensus on the management of infertile men with elevated SDF were then formulated and adapted using the Delphi method. Results A total of 436 experts from 55 different countries submitted responses. As an initial approach, 79.1% of reproductive experts recommend lifestyle modifications for infertile men with elevated SDF, and 76.9% prescribe empiric antioxidants. Regarding antioxidant duration, 39.3% recommend 4–6 months and 38.1% recommend 3 months. For men with unexplained or idiopathic infertility, and couples experiencing recurrent miscarriages associated with elevated SDF, most respondents refer to ART 6 months after failure of conservative and empiric medical management. Infertile men with clinical varicocele, normal conventional semen parameters, and elevated SDF are offered varicocele repair immediately after diagnosis by 31.4%, and after failure of antioxidants and conservative measures by 40.9%. Sperm selection techniques and testicular sperm extraction are also management options for couples undergoing ART. For most questions, heterogenous practices were demonstrated. Conclusions This paper presents the results of a large global survey on the management of infertile men with elevated SDF and reveals a lack of consensus among clinicians. Furthermore, it demonstrates the scarcity of professional society guidelines in this regard and attempts to highlight the relevant evidence. Expert recommendations are proposed to help guide clinicians

    Urinary, Circulating, and Tissue Biomonitoring Studies Indicate Widespread Exposure to Bisphenol A

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    Faktor yang Berhubungan dengan Pemberian ASI Eksklusif di Wilayah Kerja UPTD Puskesmas Bulili Kecamatan Palu Selatan

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    ABSTRAK NOVA DWI LESTARI. Faktor yang Berhubungan dengan Pemberian ASI Eksklusif di Wilayah Kerja UPTD Puskesmas Bulili Kecamatan Palu Selatan (di bawah bimbingan Nurhaya S. Patui) Peminatan Biostatistik, KB, dan Kependudukan Program Studi Kesehatan Masyarakat Fakultas Kesehatan Masyarakat Universitas Tadulako Februari 2021 ASI merupakan makanan paling ideal baik secara fisiologis maupun biologis yang harus diberikan kepada bayi diawal kehidupannya. Penerapan pola pemberian ASI eksklusif belum dilaksanakan dengan baik di Indonesia. Di Indonesia meskipun sebagian besar perempuan (96%) menyusui bayinya, namun hanya 42% dari bayi yang berusia di bawah 6 bulan yang mendapatkan ASI eksklusif. Berdasarkan data Dinas Kesehatan Kota Palu, cakupan pemberian ASI Eksklusif pada tahun 2018 yaitu 59,9% dan Wilayah kerja UPTD Puskesmas Bulili berada di posisi terendah dengan persentase 37,17%. Tujuan penelitian ini untuk mengetahui faktor yang berhubungan dengan pemberian ASI eksklusif di wilayah kerja UPTD Puskesmas Bulili Kecamatan Palu Selatan. Jenis penelitian adalah kuantitatif dengan pendekatan cross sectional. Sampel sebanyak 97 ibu yang memiliki bayi usia 6-12 bulan. Teknik pengambilan sampel menggunakan teknik simple random sampling. Analisis yang digunakan yaitu uji chi-square dengan nilai α 0,05. Hasil penelitian menunjukkan bahwa pengetahuan (p=0,000), status pekerjaan ibu (p=0,000), ketertarikan promosi susu formula (p=0,000), dan dukungan keluarga (p=0,000) berhubungan dengan keberhasilan pemberian ASI eksklusif pada bayi usia 6- 12 bulan. Sebaiknya pihak Puskesmas khususnya bidan dan kader lebih aktif dalam melakukan penyuluhan mengenai pemberian ASI eksklusif kepada ibu maupun keluarga serta memberikan pendampingan kepada ibu menyusui di 6 bulan pertama. Dan juga perlunya dibangun komitmen antara bidan dan ibu agar tidak mengizinkan ibu memberikan makanan pralaktal pada bayi pasca melahirkan. Dan juga perlu adanya upaya pemerintah Kota Palu untuk mensosialisasikan kebijakan penyediaan ruang laktasi secara konsisten di kantor maupun perusahaan. Kata Kunci: ASI Eksklusif, Pengetahuan, Promosi Susu Formula, Dukungan Keluarga, Puskesmas Bulil

    Δ\Delta(1232) Dalitz decay in proton-proton collisions at T=1.25 GeV measured with HADES at GSI

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    We report on the investigation of Δ(1232) production and decay in proton-proton collisions at a kinetic energy of 1.25 GeV measured with HADES. Exclusive dilepton decay channels ppe+e− and ppe+e−γ have been studied and compared with the partial-wave analysis of the hadronic ppπ0 channel. They allow to access both Δ+→pπ0(e+e−γ) and Δ+→pe+e− Dalitz decay channels. The perfect reconstruction of the well-known π0 Dalitz decay serves as a proof of the consistency of the analysis. The Δ Dalitz decay is identified for the first time and the sensitivity to N-Δ transition form factors is tested. The Δ(1232) Dalitz decay branching ratio is also determined for the first time; our result is (4.19 ± 0.62 syst. ± 0.34 stat.) ×10−5, albeit with some model dependence.Peer Reviewe
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