ESTÁGIO SUPERVISIONADO CIÊNCIAS CONTÁBEIS: EMPRESA VILLE INDÚSTRIA DE LICORES LTDA

Este trabalho foi desenvolvido estabelecendo laços entre a teoria e a prática contábil. Foi criada uma indústria de bebidas destiladas, que recebeu o nome fantasia de Ville Indústria de Licores Ltda. A etapa inicial foi a constituição da empresa voltada especificamente à produção de licores com sabores e composições diferentes, sem conservantes químicos. Foram aplicados estudos voltados ao seu processo produtivo, legislação trabalhista e tributária, cálculos de preço de venda, mark-up e ponto de equilíbrio. Na segunda etapa, foi aplicado um sistema contábil a partir de cálculos demonstrativos das operações realizadas pela empresa. Com isso, foi possível efetuar os lançamentos contábeis, a apuração de impostos, a elaboração das demonstrações contábeis e as análises financeiras obtidas dos cálculos de indicadores. Os resultados demonstraram que a Contabilidade tem como essência a teoria executada na prática. Esses meios são fontes de informações gerenciais para uma melhor tomada de decisão do gestor e do investidor. A atividade demonstrou que, apesar da elevada carga tributária da empresa, suas margens são positivas, pois possui uma grande procura do mercado.Palavras chave: Licores. Pesquisas. Princípios contábeis

Understanding global changes of the liver proteome during murine schistosomiasis using a label-free shotgun approach.

Schistosomiasis is an endemic disease affecting over 207million people worldwide caused by helminth parasites of the genus Schistosoma. In Brazil the disease is responsible for the loss of up to 800 lives annually, resulting from the desabilitating effects of this chronic condition. In this study, we infected Balb/c mice with Schistosoma mansoni and analysed global changes in the proteomic profile of soluble liver proteins. Our shotgun analyses revealed predominance of up-regulation of proteins at 5weeks of infection, coincidingwith the onset of egg laying, and a remarkable down-regulation of liver constituents at 7 weeks, when severe tissue damage is installed. Representatives of glycolytic enzymes and stress response (in particular at the endoplasmic reticulum)were among the most differentially expressed molecules found in the infected liver. Collectively, our data contribute over 70 molecules not previously reported to be found at altered levels in murine schistosomiasis to further exploration of their potential as biomarkers of the disease.Moreover, understanding their intricate interaction using bioinformatics approach can potentially bring clarity to unknownmechanisms linked to the establishment of this condition in the vertebrate host. Significance: To our knowledge, this study refers to the first shotgun proteomic analysis to provide an inventory of the global changes in the liver soluble proteome caused by Schistosomamansoni in the Balb/cmodel. It also innovates by yielding data on quantification of the identified molecules as a manner to clarify and give insights into the underlying mechanisms for establishment of Schistosomiasis, a neglected tropical disease with historical prevalence in Brazil

Search for new phenomena in final states with an energetic jet and large missing transverse momentum in pp collisions at √ s = 8 TeV with the ATLAS detector

Results of a search for new phenomena in final states with an energetic jet and large missing transverse momentum are reported. The search uses 20.3 fb−1 of √ s = 8 TeV data collected in 2012 with the ATLAS detector at the LHC. Events are required to have at least one jet with pT > 120 GeV and no leptons. Nine signal regions are considered with increasing missing transverse momentum requirements between Emiss T > 150 GeV and Emiss T > 700 GeV. Good agreement is observed between the number of events in data and Standard Model expectations. The results are translated into exclusion limits on models with either large extra spatial dimensions, pair production of weakly interacting dark matter candidates, or production of very light gravitinos in a gauge-mediated supersymmetric model. In addition, limits on the production of an invisibly decaying Higgs-like boson leading to similar topologies in the final state are presente

Two new species of Odontostilbe historically hidden under O. microcephala (Characiformes: Cheirodontinae)

Specimens historically identified as Odontostilbe microcephala from the upper rio Paraná and Andean piedmont tributaries of the río Paraguay are reviewed and split in three species. We found that the distribution of O. microcephala is restricted to the Andean slope of the río Paraguay basin. The species is distinguished from congeners with subterminal mouth by the elongate body, usually 10-12 gill rakers on upper branch and smaller horizontal orbital diameter (24.6-32.8 % HL, mean 28.7%). Specimens from upper rio Paraná constitute two new species, diagnosed from other Cheirodontinae by the presence of mesopterygoid teeth, grouped on median portion and forming a continuous row. The new species are distinguished from each other by having premaxillary teeth with five cusps vs. nine cusps and by the number of lamellae in left and right sides of central median raphe of olfactory rosette with 20-21 vs. 11-12.Espécimes historicamente identificados com Odontostilbe microcephala do rio Paraná e tributários do río Paraguay, foram revisados e separados em três espécies. A distribuição de O. microcephala é restrita ao sopé andino da bacia do río Paraguay. A espécie é distinta das congêneres com boca subterminal pela forma alongada, geralmente 10-12 rastros branquiais no ramo superior e menor diâmetro horizontal da órbita (24,6-32,8 % CC, média 28,7%). Espécimes do alto rio Paraná constituem duas espécies novas diagnosticadas de outros Cheirodontinae pela presença de dentes no mesopterigoide, agrupados em sua porção média e formando uma fileira continua. As novas espécies distinguem-se por ter dentes premaxilares com cinco cúspides vs. nove cúspides e pelo número de lamelas nos lados esquerdo e direito da rafe central da roseta olfativa com 20-21 vs. 11-12