f(R) actions, cosmic acceleration and local tests of gravity

We study spherically symmetric solutions in f(R) theories and its compatibility with local tests of gravity. We start by clarifying the range of validity of the weak field expansion and show that for many models proposed to address the Dark Energy problem this expansion breaks down in realistic situations. This invalidates the conclusions of several papers that make inappropriate use of this expansion. For the stable models that modify gravity only at small curvatures we find that when the asymptotic background curvature is large we approximately recover the solutions of Einstein gravity through the so-called Chameleon mechanism, as a result of the non-linear dynamics of the extra scalar degree of freedom contained in the metric. In these models one would observe a transition from Einstein to scalar-tensor gravity as the Universe expands and the background curvature diminishes. Assuming an adiabatic evolution we estimate the redshift at which this transition would take place for a source with given mass and radius. We also show that models of dynamical Dark Energy claimed to be compatible with tests of gravity because the mass of the scalar is large in vacuum (e.g. those that also include R^2 corrections in the action), are not viable.Comment: 26 page

External Fields as a Probe for Fundamental Physics

Quantum vacuum experiments are becoming a flexible tool for investigating fundamental physics. They are particularly powerful for searching for new light but weakly interacting degrees of freedom and are thus complementary to accelerator-driven experiments. I review recent developments in this field, focusing on optical experiments in strong electromagnetic fields. In order to characterize potential optical signatures, I discuss various low-energy effective actions which parameterize the interaction of particle-physics candidates with optical photons and external electromagnetic fields. Experiments with an electromagnetized quantum vacuum and optical probes do not only have the potential to collect evidence for new physics, but special-purpose setups can also distinguish between different particle-physics scenarios and extract information about underlying microscopic properties.Comment: 12 pages, plenary talk at QFEXT07, Leipzig, September 200

Dark spinor models in gravitation and cosmology

We introduce and carefully define an entire class of field theories based on non-standard spinors. Their dominant interaction is via the gravitational field which makes them naturally dark; we refer to them as Dark Spinors. We provide a critical analysis of previous proposals for dark spinors noting that they violate Lorentz invariance. As a working assumption we restrict our analysis to non-standard spinors which preserve Lorentz invariance, whilst being non-local and explicitly construct such a theory. We construct the complete energy-momentum tensor and derive its components explicitly by assuming a specific projection operator. It is natural to next consider dark spinors in a cosmological setting. We find various interesting solutions where the spinor field leads to slow roll and fast roll de Sitter solutions. We also analyse models where the spinor is coupled conformally to gravity, and consider the perturbations and stability of the spinor.Comment: 43 pages. Several new sections and details added. JHEP in prin

Comparing two approaches to Hawking radiation of Schwarzschild-de Sitter black holes

We study two different ways to analyze the Hawking evaporation of a Schwarzschild-de Sitter black hole. The first one uses the standard approach of surface gravity evaluated at the possible horizons. The second method derives its results via the Generalized Uncertainty Principle (GUP) which offers a yet different method to look at the problem. In the case of a Schwarzschild black hole it is known that this methods affirms the existence of a black hole remnant (minimal mass $M_{\rm min}$) of the order of Planck mass $m_{\rm pl}$ and a corresponding maximal temperature $T_{\rm max}$ also of the order of $m_{\rm pl}$. The standard $T(M)$ dispersion relation is, in the GUP formulation, deformed in the vicinity of Planck length $l_{\rm pl}$ which is the smallest value the horizon can take. We generalize the uncertainty principle to Schwarzschild-de Sitter spacetime with the cosmological constant $\varLambda=1/m_\varLambda^2$ and find a dual relation which, compared to $M_{\rm min}$ and $T_{\rm max}$, affirms the existence of a maximal mass $M_{\rm max}$ of the order $(m_{\rm pl}/m_\varLambda)m_{\rm pl}$, minimum temperature $T_{\rm min} \sim m_\varLambda$. As compared to the standard approach we find a deformed dispersion relation $T(M)$ close to $l_{\rm pl}$ and in addition at the maximally possible horizon approximately at $r_\varLambda=1/m_\varLambda$. $T(M)$ agrees with the standard results at $l_{\rm pl} \ll r \ll r_\varLambda$ (or equivalently at $M_{\rm min} \ll M \ll M_{\rm max}$).Comment: new references adde

CMS physics technical design report : Addendum on high density QCD with heavy ions

Peer reviewe

Erratum to: 36th International Symposium on Intensive Care and Emergency Medicine

[This corrects the article DOI: 10.1186/s13054-016-1208-6.]

Diminishing benefits of urban living for children and adolescents’ growth and development

Optimal growth and development in childhood and adolescence is crucial for lifelong health and well-being1–6. Here we used data from 2,325 population-based studies, with measurements of height and weight from 71 million participants, to report the height and body-mass index (BMI) of children and adolescents aged 5–19 years on the basis of rural and urban place of residence in 200 countries and territories from 1990 to 2020. In 1990, children and adolescents residing in cities were taller than their rural counterparts in all but a few high-income countries. By 2020, the urban height advantage became smaller in most countries, and in many high-income western countries it reversed into a small urban-based disadvantage. The exception was for boys in most countries in sub-Saharan Africa and in some countries in Oceania, south Asia and the region of central Asia, Middle East and north Africa. In these countries, successive cohorts of boys from rural places either did not gain height or possibly became shorter, and hence fell further behind their urban peers. The difference between the age-standardized mean BMI of children in urban and rural areas was <1.1 kg m–2 in the vast majority of countries. Within this small range, BMI increased slightly more in cities than in rural areas, except in south Asia, sub-Saharan Africa and some countries in central and eastern Europe. Our results show that in much of the world, the growth and developmental advantages of living in cities have diminished in the twenty-first century, whereas in much of sub-Saharan Africa they have amplified

Repositioning of the global epicentre of non-optimal cholesterol

High blood cholesterol is typically considered a feature of wealthy western countries1,2. However, dietary and behavioural determinants of blood cholesterol are changing rapidly throughout the world3 and countries are using lipid-lowering medications at varying rates. These changes can have distinct effects on the levels of high-density lipoprotein (HDL) cholesterol and non-HDL cholesterol, which have different effects on human health4,5. However, the trends of HDL and non-HDL cholesterol levels over time have not been previously reported in a global analysis. Here we pooled 1,127 population-based studies that measured blood lipids in 102.6 million individuals aged 18 years and older to estimate trends from 1980 to 2018 in mean total, non-HDL and HDL cholesterol levels for 200 countries. Globally, there was little change in total or non-HDL cholesterol from 1980 to 2018. This was a net effect of increases in low- and middle-income countries, especially in east and southeast Asia, and decreases in high-income western countries, especially those in northwestern Europe, and in central and eastern Europe. As a result, countries with the highest level of non-HDL cholesterol—which is a marker of cardiovascular risk—changed from those in western Europe such as Belgium, Finland, Greenland, Iceland, Norway, Sweden, Switzerland and Malta in 1980 to those in Asia and the Pacific, such as Tokelau, Malaysia, The Philippines and Thailand. In 2017, high non-HDL cholesterol was responsible for an estimated 3.9 million (95% credible interval 3.7 million–4.2 million) worldwide deaths, half of which occurred in east, southeast and south Asia. The global repositioning of lipid-related risk, with non-optimal cholesterol shifting from a distinct feature of high-income countries in northwestern Europe, north America and Australasia to one that affects countries in east and southeast Asia and Oceania should motivate the use of population-based policies and personal interventions to improve nutrition and enhance access to treatment throughout the world

Effects of hospital facilities on patient outcomes after cancer surgery: an international, prospective, observational study

Background Early death after cancer surgery is higher in low-income and middle-income countries (LMICs) compared with in high-income countries, yet the impact of facility characteristics on early postoperative outcomes is unknown. The aim of this study was to examine the association between hospital infrastructure, resource availability, and processes on early outcomes after cancer surgery worldwide.Methods A multimethods analysis was performed as part of the GlobalSurg 3 study-a multicentre, international, prospective cohort study of patients who had surgery for breast, colorectal, or gastric cancer. The primary outcomes were 30-day mortality and 30-day major complication rates. Potentially beneficial hospital facilities were identified by variable selection to select those associated with 30-day mortality. Adjusted outcomes were determined using generalised estimating equations to account for patient characteristics and country-income group, with population stratification by hospital.Findings Between April 1, 2018, and April 23, 2019, facility-level data were collected for 9685 patients across 238 hospitals in 66 countries (91 hospitals in 20 high-income countries; 57 hospitals in 19 upper-middle-income countries; and 90 hospitals in 27 low-income to lower-middle-income countries). The availability of five hospital facilities was inversely associated with mortality: ultrasound, CT scanner, critical care unit, opioid analgesia, and oncologist. After adjustment for case-mix and country income group, hospitals with three or fewer of these facilities (62 hospitals, 1294 patients) had higher mortality compared with those with four or five (adjusted odds ratio [OR] 3.85 [95% CI 2.58-5.75]; p<0.0001), with excess mortality predominantly explained by a limited capacity to rescue following the development of major complications (63.0% vs 82.7%; OR 0.35 [0.23-0.53]; p<0.0001). Across LMICs, improvements in hospital facilities would prevent one to three deaths for every 100 patients undergoing surgery for cancer.Interpretation Hospitals with higher levels of infrastructure and resources have better outcomes after cancer surgery, independent of country income. Without urgent strengthening of hospital infrastructure and resources, the reductions in cancer-associated mortality associated with improved access will not be realised