348 research outputs found
Milwaukee Radio Public File Data, 1998-2011: An Empirical Analysis of Issue Advertising After the BCRA and Citizens United
An Opening for Quid pro Quo Corruption? Issue Advertising in Wisconsin Judicial Races Before and After Citizens United
Observable Signatures of Planet Accretion in Red Giant Stars I: Rapid Rotation and Light Element Replenishment
The orbital angular momentum of a close-orbiting giant planet can be
sufficiently large that, if transferred to the envelope of the host star during
the red giant branch (RGB) evolution, it can spin-up the star's rotation to
unusually large speeds. This spin-up mechanism is one possible explanation for
the rapid rotators detected among the population of generally slow-rotating red
giant stars. These rapid rotators thus comprise a unique stellar sample
suitable for searching for signatures of planet accretion in the form of
unusual stellar abundances due to the dissemination of the accreted planet in
the stellar envelope. In this study, we look for signatures of replenishment in
the Li abundances and (to a lesser extent) 12C/13C, which are both normally
lowered during RGB evolution. Accurate abundances were measured from high
signal-to-noise echelle spectra for samples of both slow and rapid rotator red
giant stars. We find that the rapid rotators are on average enriched in lithium
compared to the slow rotators, but both groups of stars have identical
distributions of 12C/13C within our measurement precision. Both of these
abundance results are consistent with the accretion of planets of only a few
Jupiter masses. We also explore alternative scenarios for understanding the
most Li-rich stars in our sample---particularly Li regeneration during various
stages of stellar evolution. Finally, we find that our stellar samples show
non-standard abundances even at early RGB stages, suggesting that initial
protostellar Li abundances and 12C/13C may be more variable than originally
thought.Comment: Accepted for publication in the Astrophysical Journal. 29 pages in
emulateapj format, including 16 figures and 12 tables. Tables 4 and 8 are
provided in their entirety as plain text ancillary files (and will also be
available in the electronic edition of ApJ
Mirror Self Recognition and Self-Identification
That great apes are the only primates to recognise their reflections is often taken to show that they are self-aware – however, there has been much recent debate about whether the self-awareness in question is psychological or bodily self-awareness. This paper argues that whilst self-recognition does not require psychological self-awareness, to claim that it requires only bodily self-awareness would leave something out. That is that self-recognition requires ‘objective self-awareness’ – the capacity for first person thoughts like ‘that’s me’, which involve self-identification and so are vulnerable to error through misidentification. This objective self-awareness is distinct from bodily or psychological self-awareness, requires cognitive sophistication and provides the beginnings of a more conceptual self-representation which might play a role in planning, mental time travel and theory of mind.This work was supported by a research studentship from Peterhouse, University of Cambridge
The Association Between Imitation Recognition and Socio-communicative Competencies in Chimpanzees (Pan troglodytes)
Imitation recognition provides a viable platform from which advanced social cognitive skills may develop. Despite evidence that non-human primates are capable of imitation recognition, how this ability is related to social cognitive skills is unknown. In this study, we compared imitation recognition performance, as indicated by the production of testing behaviors, with performance on a series of tasks that assess social and physical cognition in 49 chimpanzees. In the initial analyses, we found that males were more responsive than females to being imitated and engaged in significantly greater behavior repetitions and testing sequences. We also found that subjects who consistently recognized being imitated performed better on social but not physical cognitive tasks, as measured by the Primate Cognitive Test Battery. These findings suggest that the neural constructs underlying imitation recognition are likely associated with or among those underlying more general socio-communicative abilities in chimpanzees. Implications regarding how imitation recognition may facilitate other social cognitive processes, such as mirror self-recognition, are discussed
First-time rhesus monkey mothers, and mothers of sons, preferentially engage in face-to-face interactions with infants
Face-to-face interactions between mothers and infants occur in both human and non-human primates, but there is large variability in the occurrence of these behaviors and the reason for this variability remains largely unexplored. Other types of maternal investment have been shown to be dependent on infant sex (e.g. milk production and maternal responsiveness) and maternal experience (e.g. symmetrical communication). Thus, we sought to determine whether variability in face-to-face interactions, that is, mutual gazing (MG), which are hypothesized to be important for later socio-cognitive development, could be explained by these variables. We studied 28 semi-free ranging rhesus monkey (Macaca mulatta) mother-infant dyads (6 primiparous; 12 male infants) born and reared at the Laboratory of Comparative Ethology field station at the NIH Animal Center in Poolesville, MD, across the first 90 postnatal days. Infant sex (i.e. male) was a significant predictor of maternal grooming (β ± SE = 0.359 ± 0.164, Z = 2.19, P = 0.029) whereas both parity (i.e. first time mothers) and infant sex (i.e. male) significantly predicted MG (parity: β ± SE = -0.735 ± 0.223, Z = -3.30, P < 0.001; infant sex: β ± SE = 0.436 ± 0.201, Z = 2.17, P = 0.029). Separation from the mother (outside of arm's reach) was not influenced by parity or infant sex. Together with existing literature, these findings point toward differential maternal investment for sons versus daughters. Mothers may be investing differentially in sons, behaviorally, to ensure their future social competence and thus later reproductive success. Collectively, our findings add to the literature that is beginning to identify early life experiences that may lead to sex differences in neurological and behavioral development.Division of Intramural Research, National Institute of Child Health and Human Developmen
The development and optimisation of Nanobody based electrochemical immunosensors for IgG
Biosensors are increasingly heralded for their potential to create inexpensive diagnostic devices which are sensitive, selective and easy to use. One of the key categories of biosensor are immunosensors, which have historically used antibodies as bioreceptors. Though widely used, antibodies bring inherent limitations such as variability, limited stability and their reliance on animal sources. This has led to the development of alternative immuno-reagents such as non-antibody binding proteins (NABPs). These are low molecular weight proteins which largely avoid the aforementioned advantages of antibodies. They are commonly produced by bacteria enabling the use of DNA technology to manipulate bioreceptors at the molecular level. Single chain VHHs (commonly known as nanobodies) are an antibody derived NABP adapted from camelid heavy chain antibodies which are the isolated binding domain. Whilst nanobodies have been used for diagnostic and therapeutic applications, they have limited demonstration in biosensors. In this study, both antibodies and nanobodies were used to construct a biosensor. In addition nanobody performance was optimised by introducing a novel peptide spacer. The role of nanobody orientation and spacing was thus investigated and spacer length was optimised, leading to an increase in the sensitivity of the biosensor
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