271 research outputs found

    Comparative Analysis of Single- and Dual-media Thermocline Tanks for Thermal Energy Storage in Concentrating Solar Power Plants

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    A molten-salt thermocline tank is a low-cost option for thermal energy storage (TES) in concentrating solar power (CSP) plants. Typical dual-media thermocline (DMT) tanks contain molten salt and a filler material that provides sensible heat capacity at reduced cost. However, conventional quartzite rock filler introduces the potential for thermomechanical failure by successive thermal ratcheting of the tank wall under cyclical operation. To avoid this potential mode of failure, the tank may be operated as a singlemedium thermocline (SMT) tank containing solely molten salt. However, in the absence of filler material to dampen tank-scale convection eddies, internal mixing can reduce the quality of the stored thermal energy. To assess the relative merits of these two approaches, the operation of DMT and SMT tanks is simulated under different periodic charge/discharge cycles and tank wall boundary conditions to compare the performance with and without a filler material. For all conditions assessed, both thermocline tank designs have excellent thermal storage performance, although marginally higher firstand second-law efficiencies are predicted for the SMT tank. While heat loss through the tank wall to the ambient induces internal flow nonuniformities in the SMT design over the scale of the entire tank, strong stratification maintains separation of the hot and cold regions by a narrow thermocline; thermocline growth is limited by the low thermal diffusivity of the molten salt. Heat transport and flow phenomena inside the DMT tank, on the other hand, are governed to a great extent by thermal diffusion, which causes elongation of the thermocline. Both tanks are highly resistant to performance loss over periods of static operation, and the deleterious effects of dwell time are limited in both tank designs

    Visualizing Near-Wall Two-Phase Flow Morphology During Confined and Submerged Jet Impingement Boiling to the Point of Critical Heat Flux

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    Confined and submerged two-phase jet impingement is a compact, low-pressure-drop solution for high heat flux dissipation from electronic components. Nucleate boiling can be sustained up to significantly higher heat fluxes during two-phase jet impingement as compared to pool boiling. The increases in critical heat flux are explained via hydrodynamic mechanisms that have been debated in the literature. In this study, the two-phase flow morphology of a single subcooled jet of water that impinges on a circular heat source is visualized at high speed with synchronized top and side views of the confinement gap. The impinging jet issues from a 3.75-mm-diameter orifice that is held at a height of 2 orifice diameters above a 25.4-mm-diameter heat source. The experiments are conducted at a jet Reynolds number of 15,000 and a jet inlet subcooling of 10 degrees C across a range of heat fluxes up to the critical heat flux. When boiling occurs under subcooled exit flow conditions and at moderate heat fluxes, a regular cycle is observed of formation and collapse of vapor structures that bridge the heated surface and the orifice plate, which causes significant oscillations in the pressure drop. Under saturated exit flow conditions, the vapor agglomerates in the confinement gap into a bowl-like vapor structure that recurrently shrinks, due to vapor break-off at the edge of the orifice plate, and is again replenished due to vapor generation at the heater surface. The optical visualizations from the top of the confinement gap provide a unique perspective and indicate that the liquid jet flows downwards through the vapor structure, impinges on the heated surface, and then flows underneath the vapor structure as a fluid wall jet that wets the heated surface upon which discrete bubbles are generated due to boiling. At high heat fluxes, intense vapor generation causes the fluid wall jet to transition from a bubbly to a churn-like regime, shearing off some liquid droplets into the vapor structure. The origin of critical heat flux appears to result from a significant portion of the liquid in the wall jet being deflected off the surface, and the remaining liquid film on the surface drying out before reaching the edge of the heater

    Three-Dimensional Liquid-Vapor Interface Reconstruction from High-Speed Stereo Images during Pool Boiling

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    A technique for reconstruction of liquid-gas interfaces based on high-speed stereo-imaging is applied to the liquid-vapor interfaces formed above a heated surface during pool boiling. Template matching is used for determining the correspondence of local features of the liquid-vapor interfaces between the two camera views. A sampling grid is overlaid on the reference image, and windows centered at each sampled pixel are compared with windows centered along the epipolar line in the target image to obtain a correlation signal. The three-dimensional coordinates of each matched pixel are determined via triangulation, which yields the physical world representation of the liquid-vapor interface. Liquid-vapor interface reconstruction is demonstrated during pool boiling for a range of heat fluxes. Textured mushroom-like vapor bubbles that are fed by multiple nucleation sites are formed close to the heated surface. Analysis of the temporal attributes of the interface distinguishes the transition with increasing heat flux from a mode in which vapor is released from the surface as a continuous plume to one dominated by the occurrence of intermittent vapor bursts. A characteristic morphology of the vapor mushroom formed during vapor burst events is identified. This liquid-vapor interface reconstruction technique is a time-resolved, flexible and non-invasive alternative to existing methods for phase-distribution mapping, and can be combined with other opticalbased diagnostic tools, such as tomographic particle image velocimetry. Vapor flow morphology characterization during pool boiling at high heat fluxes can be used to inform vapor removal strategies that delay the occurrence of critical heat flux during pool boiling

    Short and Long-Term Sensitivity of Lab-Scale Thermocline Based Thermal Storage to Flow Disturbances

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    Molten-salt thermocline-based systems are a low-cost option for single-tank thermal energy storage in concentrated solar power plants. Due to the high variability in solar energy availability, these energy storage devices are subject to transient heat loads during charging that can affect the storage efficiency. Numerical simulations were conducted to analyze the stability characteristics of a lab-scale thermocline tank subject to a flow disturbance during charging under different operating temperatures. The charging process was first simulated at a constant Reynolds number for three different Atwood numbers; a stably stratified fluid layer develops inside the storage tank in all cases. A flow disturbance was then introduced at the inlet of the stratified thermocline tank by inserting colder fluid for a short period of time. The disturbance interacts with the thermocline and causes oscillations and mixing. The thermocline oscillations are under-damped and lead to an increase in thermocline region thickness. The transient behavior of the thermocline and the decay rate in its oscillations were analyzed; the damping time depends on the Atwood number. The persistence of flow disturbance effects during long-term cyclical operation was also investigated. Several charge/discharge cycles were simulated at constant Reynolds number to obtain a time-periodic thermal response for each Atwood number. The characteristic flow disturbance was introduced at the inlet during a single charging process, and the thermocline region was observed during several subsequent charge/discharge cycles to assess the long-term temporal attenuation of the disturbance. The thermocline almost fully recovers to the time-periodic behavior after a single cycle

    Assessment of plasma chitotriosidase activity, CCL18/PARC concentration and NP-C suspicion index in the diagnosis of Niemann-Pick disease type C: A prospective observational study

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    Background: Niemann-Pick disease type C (NP-C) is a rare, autosomal recessive neurodegenerative disease caused by mutations in either the NPC1 or NPC2 genes. The diagnosis of NP-C remains challenging due to the non-specific, heterogeneous nature of signs/symptoms. This study assessed the utility of plasma chitotriosidase (ChT) and Chemokine (C-C motif) ligand 18 (CCL18)/pulmonary and activation-regulated chemokine (PARC) in conjunction with the NP-C suspicion index (NP-C SI) for guiding confirmatory laboratory testing in patients with suspected NP-C. Methods: In a prospective observational cohort study, incorporating a retrospective determination of NP-C SI scores, two different diagnostic approaches were applied in two separate groups of unrelated patients from 51 Spanish medical centers (n = 118 in both groups). From Jan 2010 to Apr 2012 (Period 1), patients with =2 clinical signs/symptoms of NP-C were considered ''suspected NP-C'' cases, and NPC1/NPC2 sequencing, plasma chitotriosidase (ChT), CCL18/PARC and sphingomyelinase levels were assessed. Based on findings in Period 1, plasma ChT and CCL18/PARC, and NP-C SI prediction scores were determined in a second group of patients between May 2012 and Apr 2014 (Period 2), and NPC1 and NPC2 were sequenced only in those with elevated ChT and/or elevated CCL18/PARC and/or NP-C SI =70. Filipin staining and 7-ketocholesterol (7-KC) measurements were performed in all patients with NP-C gene mutations, where possible. Results: In total across Periods 1 and 2, 10/236 (4%) patients had a confirmed diagnosis o NP-C based on gene sequencing (5/118 4.2%] in each Period): all of these patients had two causal NPC1 mutations. Single mutant NPC1 alleles were detected in 8/236 (3%) patients, overall. Positive filipin staining results comprised three classical and five variant biochemical phenotypes. No NPC2 mutations were detected. All patients with NPC1 mutations had high ChT activity, high CCL18/PARC concentrations and/or NP-C SI scores =70. Plasma 7-KC was higher than control cut-off values in all patients with two NPC1 mutations, and in the majority of patients with single mutations. Family studies identified three further NP-C patients. Conclusion: This approach may be very useful for laboratories that do not have mass spectrometry facilities and therefore, they cannot use other NP-C biomarkers for diagnosis

    Penilaian Kinerja Keuangan Koperasi di Kabupaten Pelalawan

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    This paper describe development and financial performance of cooperative in District Pelalawan among 2007 - 2008. Studies on primary and secondary cooperative in 12 sub-districts. Method in this stady use performance measuring of productivity, efficiency, growth, liquidity, and solvability of cooperative. Productivity of cooperative in Pelalawan was highly but efficiency still low. Profit and income were highly, even liquidity of cooperative very high, and solvability was good

    Juxtaposing BTE and ATE – on the role of the European insurance industry in funding civil litigation

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    One of the ways in which legal services are financed, and indeed shaped, is through private insurance arrangement. Two contrasting types of legal expenses insurance contracts (LEI) seem to dominate in Europe: before the event (BTE) and after the event (ATE) legal expenses insurance. Notwithstanding institutional differences between different legal systems, BTE and ATE insurance arrangements may be instrumental if government policy is geared towards strengthening a market-oriented system of financing access to justice for individuals and business. At the same time, emphasizing the role of a private industry as a keeper of the gates to justice raises issues of accountability and transparency, not readily reconcilable with demands of competition. Moreover, multiple actors (clients, lawyers, courts, insurers) are involved, causing behavioural dynamics which are not easily predicted or influenced. Against this background, this paper looks into BTE and ATE arrangements by analysing the particularities of BTE and ATE arrangements currently available in some European jurisdictions and by painting a picture of their respective markets and legal contexts. This allows for some reflection on the performance of BTE and ATE providers as both financiers and keepers. Two issues emerge from the analysis that are worthy of some further reflection. Firstly, there is the problematic long-term sustainability of some ATE products. Secondly, the challenges faced by policymakers that would like to nudge consumers into voluntarily taking out BTE LEI

    Search for stop and higgsino production using diphoton Higgs boson decays

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    Results are presented of a search for a "natural" supersymmetry scenario with gauge mediated symmetry breaking. It is assumed that only the supersymmetric partners of the top-quark (stop) and the Higgs boson (higgsino) are accessible. Events are examined in which there are two photons forming a Higgs boson candidate, and at least two b-quark jets. In 19.7 inverse femtobarns of proton-proton collision data at sqrt(s) = 8 TeV, recorded in the CMS experiment, no evidence of a signal is found and lower limits at the 95% confidence level are set, excluding the stop mass below 360 to 410 GeV, depending on the higgsino mass

    Severe early onset preeclampsia: short and long term clinical, psychosocial and biochemical aspects

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    Preeclampsia is a pregnancy specific disorder commonly defined as de novo hypertension and proteinuria after 20 weeks gestational age. It occurs in approximately 3-5% of pregnancies and it is still a major cause of both foetal and maternal morbidity and mortality worldwide1. As extensive research has not yet elucidated the aetiology of preeclampsia, there are no rational preventive or therapeutic interventions available. The only rational treatment is delivery, which benefits the mother but is not in the interest of the foetus, if remote from term. Early onset preeclampsia (<32 weeks’ gestational age) occurs in less than 1% of pregnancies. It is, however often associated with maternal morbidity as the risk of progression to severe maternal disease is inversely related with gestational age at onset2. Resulting prematurity is therefore the main cause of neonatal mortality and morbidity in patients with severe preeclampsia3. Although the discussion is ongoing, perinatal survival is suggested to be increased in patients with preterm preeclampsia by expectant, non-interventional management. This temporising treatment option to lengthen pregnancy includes the use of antihypertensive medication to control hypertension, magnesium sulphate to prevent eclampsia and corticosteroids to enhance foetal lung maturity4. With optimal maternal haemodynamic status and reassuring foetal condition this results on average in an extension of 2 weeks. Prolongation of these pregnancies is a great challenge for clinicians to balance between potential maternal risks on one the eve hand and possible foetal benefits on the other. Clinical controversies regarding prolongation of preterm preeclamptic pregnancies still exist – also taking into account that preeclampsia is the leading cause of maternal mortality in the Netherlands5 - a debate which is even more pronounced in very preterm pregnancies with questionable foetal viability6-9. Do maternal risks of prolongation of these very early pregnancies outweigh the chances of neonatal survival? Counselling of women with very early onset preeclampsia not only comprises of knowledge of the outcome of those particular pregnancies, but also knowledge of outcomes of future pregnancies of these women is of major clinical importance. This thesis opens with a review of the literature on identifiable risk factors of preeclampsia

    Finishing the euchromatic sequence of the human genome

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    The sequence of the human genome encodes the genetic instructions for human physiology, as well as rich information about human evolution. In 2001, the International Human Genome Sequencing Consortium reported a draft sequence of the euchromatic portion of the human genome. Since then, the international collaboration has worked to convert this draft into a genome sequence with high accuracy and nearly complete coverage. Here, we report the result of this finishing process. The current genome sequence (Build 35) contains 2.85 billion nucleotides interrupted by only 341 gaps. It covers ∼99% of the euchromatic genome and is accurate to an error rate of ∼1 event per 100,000 bases. Many of the remaining euchromatic gaps are associated with segmental duplications and will require focused work with new methods. The near-complete sequence, the first for a vertebrate, greatly improves the precision of biological analyses of the human genome including studies of gene number, birth and death. Notably, the human enome seems to encode only 20,000-25,000 protein-coding genes. The genome sequence reported here should serve as a firm foundation for biomedical research in the decades ahead
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