[Review of] John E. Fleming, Gerald R. Gill, and David H. Swinton. The Case for Affirmative Action for Blacks in Higher Education .

The case for affirmative action has become a major problematic concern within the last several years. Beginning with the notorious Bakke vs. the Regents of the University of California, 1978, and cresting with the recent ultraconservative stance taken by at least the most vocal members of the Civil Rights Commission, affirmative action may very well be the tidal wave that washed against the minds of those who are actively involved in obliterating racism, as well as those who remain unmindful of the beast. The Case For Affirmative Action for Blacks in Higher Education deserves to once again be taken down from our shelves, dusted, and ruminated intellectually

A study of the electric quadrupole interaction of Hf-ions in barium titanate by perturbed angular correlation.

Dept. of Physics. Paper copy at Leddy Library: Theses & Major Papers - Basement, West Bldg. / Call Number: Thesis1978 .M388. Source: Masters Abstracts International, Volume: 40-07, page: . Thesis (M.Sc.)--University of Windsor (Canada), 1978

The Postdivorce Adjustment of Middle Class Black Women

The University Archives has determined that this item is of continuing value to OSU's history.Presenter: Barbara Huddleston-Mattai, D.S.W., Department of Sociology, The University of Tennessee at Martin - "The Postdivorce Adjustment of Middle Class Black Women".The Ohio State University College of Social Wor

Preliminary observations on the growth and survival of tiger prawn (Penaeus monodon Fabricius) postlarvae in pen-nurseries

In an attempt to ensure all-time availability of stocking materials of P. monodon Fabriciua, experiments have bean undertaken on a large scale in the lower Sunderbans area of West Bengal for growing the wild-caught post-larvae (10-12 mm) of the species to an advanced juvenile (35-45 mm) stage under semi-controlled conditions. Six nursery pens (0.1 ha each) have been installed in a large (60 ha) brackishwatar impoundment and stocked at the rate of 2.0-3.6 millions per hectare. Besides encouraging the growth of natural food, the postlarvae are fed with well balanced artificial diets having protein from both animal and plant origin. Encouraging results with high survival (upto 73%) end faster growth rates have been observed In some of the trial runs. Details of stocking density, growth rate, percentage survival and the feeding schedule etc. are presented and discussed. Various physico-chemical parameters recorded at regular intervals are also given

The 2017 Regent Landslide, Freetown Peninsula, Sierra Leone

At 06:50 on Monday 14th August 2017, a hillslope on the Freetown Peninsula, Sierra Leone, collapsed, sending 300,000 m3 of debris into the flooded valley below. As this debris mixed with floodwater it became a sediment-laden flood which entered a drainage channel and travelled 6 km to the coastline. The event destroyed nearly 400 buildings, claimed the lives of an estimated 1,100 people and affected approximately 5,000 people. The mechanism was a two-stage rainfall-triggered landslide followed by a channelised debris-laden flood. The processes were similar to the nearby 1945 event in Charlotte, which killed at least 13 people. Geomorphological mapping has identified evidence of hundreds of other large landslides that occurred before modern records, providing an appreciation of the slope processes affecting the Freetown Peninsula. Following the 2017 Regent Landslide, rehabilitation of the affected area involved a risk reduction strategy that centred on reducing population exposure. These events are a reminder that the steep slopes and valleys across the Freetown Peninsula are highly susceptible to rainfall-triggered landslides which, given the topography have a high propensity to generate high intensity landslides and debris-laden floods. Future urbanization must consider whole-catchment management, flooding and slope engineering issues to provide lasting landslide risk reduction

Cathelicidin suppresses lipid accumulation and hepatic steatosis by inhibition of the CD36 receptor.

Background and objectivesObesity is a global epidemic which increases the risk of the metabolic syndrome. Cathelicidin (LL-37 and mCRAMP) is an antimicrobial peptide with an unknown role in obesity. We hypothesize that cathelicidin expression correlates with obesity and modulates fat mass and hepatic steatosis.Materials and methodsMale C57BL/6 J mice were fed a high-fat diet. Streptozotocin was injected into mice to induce diabetes. Experimental groups were injected with cathelicidin and CD36 overexpressing lentiviruses. Human mesenteric fat adipocytes, mouse 3T3-L1 differentiated adipocytes and human HepG2 hepatocytes were used in the in vitro experiments. Cathelicidin levels in non-diabetic, prediabetic and type II diabetic patients were measured by enzyme-linked immunosorbent assay.ResultsLentiviral cathelicidin overexpression reduced hepatic steatosis and decreased the fat mass of high-fat diet-treated diabetic mice. Cathelicidin overexpression reduced mesenteric fat and hepatic fatty acid translocase (CD36) expression that was reversed by lentiviral CD36 overexpression. Exposure of adipocytes and hepatocytes to cathelicidin significantly inhibited CD36 expression and reduced lipid accumulation. Serum cathelicidin protein levels were significantly increased in non-diabetic and prediabetic patients with obesity, compared with non-diabetic patients with normal body mass index (BMI) values. Prediabetic patients had lower serum cathelicidin protein levels than non-diabetic subjects.ConclusionsCathelicidin inhibits the CD36 fat receptor and lipid accumulation in adipocytes and hepatocytes, leading to a reduction of fat mass and hepatic steatosis in vivo. Circulating cathelicidin levels are associated with increased BMI. Our results demonstrate that cathelicidin modulates the development of obesity

Arrangement of Annexin A2 tetramer and its impact on the structure and diffusivity of supported lipid bilayers

Annexins are a family of proteins that bind to anionic phospholipid membranes in a Ca2+-dependent manner. Annexin A2 forms heterotetramers (Anx A2t) with the S100A10 (p11) protein dimer. The tetramer is capable of bridging phospholipid membranes and it has been suggested to play a role in Ca2+-dependent exocytosis and cell-cell adhesion of metastatic cells. Here, we employ x-ray reflectivity measurements to resolve the conformation of Anx A2t upon Ca2+-dependent binding to single supported lipid bilayers (SLBs) composed of different mixtures of anionic (POPS) and neutral (POPC) phospholipids. Based on our results we propose that Anx A2t binds in a side-by-side configuration, i.e., both Anx A2 monomers bind to the bilayer with the p11 dimer positioned on top. Furthermore, we observe a strong decrease of lipid mobility upon binding of Anx A2t to SLBs with varying POPS content. X-ray reflectivity measurements indicate that binding of Anx A2t also increases the density of the SLB. Interestingly, in the protein-facing leaflet of the SLB the lipid density is higher than in the substrate-facing leaflet. This asymmetric densification of the lipid bilayer by Anx A2t and Ca2+ might have important implications for the biochemical mechanism of Anx A2t-induced endo- and exocytosis.Comment: 27 pages, 7 figures; supplementary material available upon request from the author

The impact on human health of car-related air pollution in the UK, 1995-2005

We have analysed the impact on human health of emissions produced by the UK car fleet in the years 1995 and 2005. Calculations were based on reported measurements of pollutant concentration, literature values of exposure response coefficients and data for mortality and morbidity. A share was attributed to the car fleet based on emissions data. Although the total distance driven in the UK increased by 16% over this period to 460 billion km, there was a significant fall in engine emissions as increasingly stringent regulations (EURO standards) were introduced. As a result there was a decrease of some 25% in the number of deaths attributable to car-related air pollution – down to 5589 in 2005. The estimated number of years of life lost at 65 000 (England and Wales) in 2005, was about half that caused by road accidents involving cars in the same year. We report further calculations which show the effect of car-related pollution on hospital admissions. Our method is straightforward, providing acceptable estimates for health impacts on the predominantly urban population of the UK. There remains a need for more work, particularly cohort studies of morbidity, to establish the long-term effects of air pollution

Changes in the Frontotemporal Cortex and Cognitive Correlates in First-Episode Psychosis

Background: Loss of cortical volume in frontotemporal regions has been reported in patients with schizophrenia and their relatives. Cortical area and thickness are determined by different genetic processes, and measuring these parameters separately may clarify disturbances in corticogenesis relevant to schizophrenia. Our study also explored clinical and cognitive correlates of these parameters.Methods: Thirty-seven patients with first-episode psychosis (34 schizophrenia, 3 schizoaffective disorder) and 38 healthy control subjects matched for age and sex took part in the study. Imaging was performed on an magnetic resonance imaging 1.5-T scanner. Area and thickness of the frontotemporal cortex were measured using a surface-based morphometry method (Freesurfer). All subjects underwent neuropsychologic testing that included measures of premorbid and current IQ, working and verbal memory, and executive function.Results: Reductions in cortical area, more marked in the temporal cortex, were present in patients. Overall frontotemporal cortical thickness did not differ between groups, although regional thinning of the right superior temporal region was observed in patients. There was a significant association of both premorbid IQ and IQ at disease onset with area, but not thickness, of the frontotemporal cortex, and working memory span was associated with area of the frontal cortex. These associations remained significant when only patients with schizophrenia were considered.Conclusions: Our results suggest an early disruption of corticogenesis in schizophrenia, although the effect of subsequent environmental factors cannot be excluded. In addition, cortical abnormalities are subject to regional variations and differ from those present in neurodegenerative diseases