83 research outputs found
A Novel Approach to Assess Opioid-Induced Bowel Dysfunction:An Experimental Model in Healthy Volunteers
Hexakis(tetraaquasodium) decavanadate(V) dihydrate
The title compound, {[Na(H2O)4]6[V10O28]·2H2O}n, crystallized from a H2O/THF/CH3CN solution (pH ca 6) containing equimolar amounts of NaVO3 and N-(2-hydroxybenzyl)-N-(2-picolyl)glycine. In the crystal structure, the decavanadate [V10O28]6− anion ( symmetry) is coordinated, via four terminal oxide ligands of V centres, to two dinuclear [{Na(H2O)3}2(μ-H2O)2]2+ units. Interconnection of these aquasodium-ion-sandwiched decavanadates to chains parallel to [001] is effected by μ-[{Na(H2O)3}2(μ-H2O)2]2+ units, bridging adjacent decavanadates via O=V. The structure is consolidated by an extensive network of O—H⋯O hydrogen bonds
Intranight polarization variability in radio-loud and radio-quiet AGN
(Abriged) Intranight polarization variability in AGN has not been studied
extensively so far. Studying the variability in polarization makes it possibly
to distinguish between different emission mechanisms. Thus it can help
answering the question if intranight variability in radio-loud and radio-quiet
AGN is of the same or of fundamentally different origin. In this paper we
investigate intranight polarization variability in AGN. Our sample consists of
28 AGN at low to moderate redshifts (0.048 < z < 1.036), 12 of which are
radio-quiet quasars (RQQs) and 16 are radio-loud blazars. The subsample of
blazars consists of eight flat-spectrum radio-quasars (FSRQs) and eight BL Lac
objects. We find clear differences between the two samples. A majority of the
radio-loud AGN show moderate to high degrees of polarization, more than half of
them also show variability in polarization. There seems to be a dividing line
for polarization intranight variability at P~5 per cent over which all objects
vary in polarization. Only two out of 12 radio-quiet quasars show polarized
emission, both at levels of P<1 per cent. The lack of polarization intranight
variability in radio-quiet AGN points towards accretion instabilities being the
cause for intranight flux variability whereas the high duty cycle of
polarization variability in radio-loud objects is more likely caused by
instabilities in the jet or changes of physical conditions in the jet plasma.Comment: Accepted for Publication in MNRAS (17 pages, 14 figures, 4 tables
Risk of multiple sclerosis after optic neuritis in patients with normal baseline brain MRI
Outer membrane protein folding from an energy landscape perspective
The cell envelope is essential for the survival of Gram-negative bacteria. This specialised membrane is densely packed with outer membrane proteins (OMPs), which perform a variety of functions. How OMPs fold into this crowded environment remains an open question. Here, we review current knowledge about OFMP folding mechanisms in vitro and discuss how the need to fold to a stable native state has shaped their folding energy landscapes. We also highlight the role of chaperones and the β-barrel assembly machinery (BAM) in assisting OMP folding in vivo and discuss proposed mechanisms by which this fascinating machinery may catalyse OMP folding
G-protein coupled receptors mediating long chain fatty acid signalling in the pancreatic beta-cell
Pre-treatment and extraction techniques for recovery of added value compounds from wastes throughout the agri-food chain
Pre-treatment and extraction techniques for recovery of added value compounds from wastes throughout the agri-food chain
The enormous quantity of food wastes discarded annually force to look for alternatives for this interesting feedstock. Thus, food bio-waste valorisation is one of the imperatives of the nowadays society. This review is the most comprehensive overview of currently existing technologies and processes in this field. It tackles classical and innovative physical, physico-chemical and chemical methods of food waste pre-treatment and extraction for recovery of added value compounds and detection by modern technologies and are an outcome of the COST Action EUBIS, TD1203 Food Waste Valorisation for Sustainable Chemicals, Materials and Fuels
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