37 research outputs found
ΠΠ‘Π "ΠΡΠΎΡΡΡΡ": Π·ΡΡΡΠ°Π²Π½ΠΈΠΉ Π°ΡΠΏΠ΅ΠΊΡ Π΄ΠΎΡΠ»ΡΠ΄ΠΆΠ΅Π½Π½Ρ (Π½Π° ΠΌΠ°ΡΠ΅ΡΡΠ°Π»Ρ Π°Π½Π³Π»ΡΠΉΡΡΠΊΠΈΡ ΡΠ° ΡΠΊΡΠ°ΡΠ½ΡΡΠΊΠΈΡ ΠΊΠ°Π·ΠΎΠΊ)
ΠΡΠΊΡΠ»ΡΡΠΈΠ½Π° Π’. Π. ΠΠ‘Π "ΠΡΠΎΡΡΡΡ": Π·ΡΡΡΠ°Π²Π½ΠΈΠΉ Π°ΡΠΏΠ΅ΠΊΡ Π΄ΠΎΡΠ»ΡΠ΄ΠΆΠ΅Π½Π½Ρ (Π½Π° ΠΌΠ°ΡΠ΅ΡΡΠ°Π»Ρ Π°Π½Π³Π»ΡΠΉΡΡΠΊΠΈΡ
ΡΠ° ΡΠΊΡΠ°ΡΠ½ΡΡΠΊΠΈΡ
ΠΊΠ°Π·ΠΎΠΊ) / Π’. Π. ΠΡΠΊΡΠ»ΡΡΠΈΠ½Π° // ΠΠ°ΡΡΠΎΠ½Π°Π»ΡΠ½ΠΈΠΉ ΡΠ½ΡΠ²Π΅ΡΡΠΈΡΠ΅Ρ Β«ΠΠ΄Π΅ΡΡΠΊΠ° ΡΡΠΈΠ΄ΠΈΡΠ½Π° Π°ΠΊΠ°Π΄Π΅ΠΌΡΡΒ». β ΠΠΈΠΏ.1. β ΠΠ΄Π΅ΡΠ° : Π€Π΅Π½ΡΠΊΡ, 2013. β C. 100-111.Π£ ΡΡΠ°ΡΡΡ Π½Π°Π΄Π°Π½ΠΎ Π·ΡΡΡΠ°Π²Π½ΠΈΠΉ Π°Π½Π°Π»ΡΠ· ΠΠ‘Π "ΠΡΠΎΡΡΡΡ" Π½Π° ΠΌΠ°ΡΠ΅ΡΡΠ°Π»Ρ Π°Π½Π³Π»ΡΠΉΒΡΡΠΊΠΈΡ
ΡΠ° ΡΠΊΡΠ°ΡΠ½ΡΡΠΊΠΈΡ
ΠΊΠ°Π·ΠΎΠΊ. ΠΡΠΎΡΡΡΡ Π΄ΠΎΡΠ»ΡΠ΄ΠΆΡΡΡΡΡΡ Π·Π° Π΄ΠΎΠΏΠΎΠΌΠΎΠ³ΠΎΡ ΠΏΡΠΎΒΡΠ΅Π΄ΡΡΠΈ ΠΏΠΎΠ»ΡΠΎΠ²ΠΎΠ³ΠΎ ΠΌΠΎΠ΄Π΅Π»ΡΠ²Π°Π½Π½Ρ Π· Π²ΠΈΠΎΠΊΡΠ΅ΠΌΠ»Π΅Π½Π½ΡΠΌ ΡΠ΄ΡΠ°, Π½Π°Π²ΠΊΠΎΠ»ΠΎΡΠ΄Π΅ΡΠ½ΠΎΡ ΡΠ°ΡΡΠΈΠ½ΠΈ (ΡΠ΅Π½ΡΡΠ°) ΡΠ° ΠΏΠ΅ΡΠΈΡΠ΅ΡΡΡ. ΠΡΡΡΠ°Π²Π½ΠΈΠΉ Π°Π½Π°Π»ΡΠ· ΡΠΏΠ΅ΡΠΈΡΡΠΊΠΈ ΡΡΡΡΠΊΡΡΡΠΈ ΠΠ‘Π "ΠΡΠΎΡΡΡΡ" Π² Π°Π½Π³Π»ΡΠΉΡΡΠΊΠΈΡ
ΡΠ° ΡΠΊΡΠ°ΡΠ½ΡΡΠΊΠΈΡ
ΠΊΠ°Π·ΠΊΠ°Ρ
Π΄ΠΎΠ·Π²ΠΎΠ»ΠΈΠ² Π²ΠΈΡΠ²ΠΈΡΠΈ Π·Π°Π³Π°Π»ΡΠ½Ρ ΡΠΈΡΠΈ ΡΠ° Π΅Π»Π΅ΠΌΠ΅Π½ΡΠΈ Π· Π½Π°ΡΡΠΎΠ½Π°Π»ΡΠ½ΠΎΒΠΊΡΠ»ΡΡΡΡΠ½ΠΎΡ ΡΠΏΠ΅ΡΠΈΡΡΠΊΠΎ
Π Π°Π΄ΠΈΠΎΠΌΠΈΡΠ΅ΡΠΊΠΈΠΉ Π°Π½Π°Π»ΠΈΠ· Π΄Π»Ρ ΠΎΠ±ΡΠ΅ΠΊΡΠΈΠ²ΠΈΠ·Π°ΡΠΈΠΈ Π΄ΠΈΠ°Π³Π½ΠΎΡΡΠΈΠΊΠΈ ΠΈ ΠΊΠΎΠΌΠΏΠ»Π΅ΠΊΡΠ½ΠΎΠ³ΠΎ Π»Π΅ΡΠ΅Π½ΠΈΡ Π³Π»ΠΈΠΎΠ±Π»Π°ΡΡΠΎΠΌΡ
Introduction. Glioblastoma is a neuroepithelial malignant brain tumour of predominantly astrocytic origin with an aggressive course and an extremely unfavorable prognosis. Since the median of overall survival with glioblastoma is 14.6 months after complex treatment that includes a combination of surgical treatment, radiation therapy and chemotherapy, the development a personalized approach in the diagnosis and treatment of glioblastomas is appeared to be urgent.Materials and methods. MRIs of a patient undergoing chemoradiotherapy for glioblastoma G4 were performed on the following MRI scanners: Philips Ingenia 1.5T and Philips Ingenia Ambient 1.5T. The analysis of MR-images was carried out using the Matlab 2021 apps.Results and discussion. MR-images were analyzed before and after surgery, and after a course of chemoradiotherapy. The statistical characteristics of the local brightness distribution of the lesion image, which are described by statistical texture parameters, were analyzed as informative features of the lesion area on the images. Initial confirmation of the ability to objectify diagnosis and treatment using the above statistical parameters of T2 MR images of lesion area has been obtained.Conclusion. The aim of further research in this area is to use radiomic study for planning and monitoring the treatment of high-grade gliomas, estimate disease outcomes, and analyze the response to complex treatments in a predictive way.ΠΠ²Π΅Π΄Π΅Π½ΠΈΠ΅. ΠΠ»ΠΈΠΎΠ±Π»Π°ΡΡΠΎΠΌΠ° β Π½Π΅ΠΉΡΠΎΡΠΏΠΈΡΠ΅Π»ΠΈΠ°Π»ΡΠ½Π°Ρ Π·Π»ΠΎΠΊΠ°ΡΠ΅ΡΡΠ²Π΅Π½Π½Π°Ρ ΠΎΠΏΡΡ
ΠΎΠ»Ρ Π³ΠΎΠ»ΠΎΠ²Π½ΠΎΠ³ΠΎ ΠΌΠΎΠ·Π³Π° ΠΏΡΠ΅ΠΈΠΌΡΡΠ΅ΡΡΠ²Π΅Π½Π½ΠΎ Π°ΡΡΡΠΎΡΠΈΡΠ°ΡΠ½ΠΎΠ³ΠΎ ΠΏΡΠΎΠΈΡΡ
ΠΎΠΆΠ΄Π΅Π½ΠΈΡ Ρ Π°Π³ΡΠ΅ΡΡΠΈΠ²Π½ΡΠΌ ΡΠ΅ΡΠ΅Π½ΠΈΠ΅ΠΌ ΠΈ ΠΊΡΠ°ΠΉΠ½Π΅ Π½Π΅Π±Π»Π°Π³ΠΎΠΏΡΠΈΡΡΠ½ΡΠΌ ΠΏΡΠΎΠ³Π½ΠΎΠ·ΠΎΠΌ. ΠΠ΅Π΄ΠΈΠ°Π½Π° ΠΎΠ±ΡΠ΅ΠΉ Π²ΡΠΆΠΈΠ²Π°Π΅ΠΌΠΎΡΡΠΈ ΠΏΡΠΈ Π³Π»ΠΈΠΎΠ±Π»Π°ΡΡΠΎΠΌΠ΅ ΡΠΎΡΡΠ°Π²Π»ΡΠ΅Ρ 14,6 ΠΌΠ΅ΡΡΡΠ° ΠΏΠΎΡΠ»Π΅ ΠΊΠΎΠΌΠΏΠ»Π΅ΠΊΡΠ½ΠΎΠ³ΠΎ Π»Π΅ΡΠ΅Π½ΠΈΡ, Π²ΠΊΠ»ΡΡΠ°ΡΡΠ΅Π³ΠΎ ΠΊΠΎΠΌΠ±ΠΈΠ½Π°ΡΠΈΡ Ρ
ΠΈΡΡΡΠ³ΠΈΡΠ΅ΡΠΊΠΎΠ³ΠΎ Π»Π΅ΡΠ΅Π½ΠΈΡ, Π»ΡΡΠ΅Π²ΠΎΠΉ ΡΠ΅ΡΠ°ΠΏΠΈΠΈ ΠΈ Ρ
ΠΈΠΌΠΈΠΎΡΠ΅ΡΠ°ΠΏΠΈΠΈ, ΡΡΠΎ Π΄ΠΈΠΊΡΡΠ΅Ρ Π½Π΅ΠΎΠ±Ρ
ΠΎΠ΄ΠΈΠΌΠΎΡΡΡ ΡΠ°Π·ΡΠ°Π±ΠΎΡΠΊΠΈ ΠΏΠ΅ΡΡΠΎΠ½Π°Π»ΠΈΠ·ΠΈΡΠΎΠ²Π°Π½Π½ΠΎΠ³ΠΎ ΠΏΠΎΠ΄Ρ
ΠΎΠ΄Π° Π² Π΄ΠΈΠ°Π³Π½ΠΎΡΡΠΈΠΊΠ΅ ΠΈ Π»Π΅ΡΠ΅Π½ΠΈΠΈ Π³Π»ΠΈΠΎΠ±Π»Π°ΡΡΠΎΠΌ.ΠΠ°ΡΠ΅ΡΠΈΠ°Π»Ρ ΠΈ ΠΌΠ΅ΡΠΎΠ΄Ρ: ΠΠ Π’-ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΡ ΠΏΠ°ΡΠΈΠ΅Π½ΡΠ°, ΠΏΡΠΎΡ
ΠΎΠ΄ΠΈΠ²ΡΠ΅Π³ΠΎ Ρ
ΠΈΠΌΠΈΠΎΠ»ΡΡΠ΅Π²ΠΎΠ΅ Π»Π΅ΡΠ΅Π½ΠΈΠ΅ ΠΏΠΎ ΠΏΠΎΠ²ΠΎΠ΄Ρ Π³Π»ΠΈΠΎΠ±Π»Π°ΡΡΠΎΠΌΡ G4, Π²ΡΠΏΠΎΠ»Π½ΡΠ»ΠΈΡΡ Π½Π° Π°ΠΏΠΏΠ°ΡΠ°ΡΠ°Ρ
: ΠΌΠ°Π³Π½ΠΈΡΠ½ΠΎ-ΡΠ΅Π·ΠΎΠ½Π°Π½ΡΠ½ΡΠΉ ΡΠΎΠΌΠΎΠ³ΡΠ°Ρ Philips Ingenia 1.5T ΠΈ Philips IngeniΠ° Πmbition 1,5 Π’. ΠΠ½Π°Π»ΠΈΠ· ΠΠ Π’-ΠΈΠ·ΠΎΠ±ΡΠ°ΠΆΠ΅Π½ΠΈΠΉ ΠΎΡΡΡΠ΅ΡΡΠ²Π»Π΅Π½ Ρ ΠΈΡΠΏΠΎΠ»ΡΠ·ΠΎΠ²Π°Π½ΠΈΠ΅ΠΌ ΠΏΠ°ΠΊΠ΅ΡΠ° ΠΏΡΠΈΠΊΠ»Π°Π΄Π½ΡΡ
ΠΏΡΠΎΠ³ΡΠ°ΠΌΠΌ Matlab 2021.Π Π΅Π·ΡΠ»ΡΡΠ°ΡΡ. ΠΡΠΎΠ°Π½Π°Π»ΠΈΠ·ΠΈΡΠΎΠ²Π°Π½Ρ ΠΠ Π’-ΠΈΠ·ΠΎΠ±ΡΠ°ΠΆΠ΅Π½ΠΈΡ Π΄ΠΎ ΠΏΡΠΎΠ²Π΅Π΄Π΅Π½ΠΈΡ Ρ
ΠΈΡΡΡΠ³ΠΈΡΠ΅ΡΠΊΠΎΠ³ΠΎ Π²ΠΌΠ΅ΡΠ°ΡΠ΅Π»ΡΡΡΠ²Π°, ΠΏΠΎΡΠ»Π΅ Ρ
ΠΈΡΡΡΠ³ΠΈΡΠ΅ΡΠΊΠΎΠ³ΠΎ Π²ΠΌΠ΅ΡΠ°ΡΠ΅Π»ΡΡΡΠ²Π° ΠΈ ΠΏΠΎΡΠ»Π΅ ΠΊΡΡΡΠ° Ρ
ΠΈΠΌΠΈΠΎΠ»ΡΡΠ΅Π²ΠΎΠ³ΠΎ Π»Π΅ΡΠ΅Π½ΠΈΡ. Π ΠΊΠ°ΡΠ΅ΡΡΠ²Π΅ ΠΈΠ½ΡΠΎΡΠΌΠ°ΡΠΈΠ²Π½ΡΡ
ΠΏΡΠΈΠ·Π½Π°ΠΊΠΎΠ² ΠΎΡΠ°Π³ΠΎΠ² ΠΏΠΎΡΠ°ΠΆΠ΅Π½ΠΈΡ Π½Π° ΠΈΠ·ΠΎΠ±ΡΠ°ΠΆΠ΅Π½ΠΈΡΡ
ΠΏΡΠΎΠ°Π½Π°Π»ΠΈΠ·ΠΈΡΠΎΠ²Π°Π½Ρ ΡΡΠ°ΡΠΈΡΡΠΈΡΠ΅ΡΠΊΠΈΠ΅ Ρ
Π°ΡΠ°ΠΊΡΠ΅ΡΠΈΡΡΠΈΠΊΠΈ Π»ΠΎΠΊΠ°Π»ΡΠ½ΠΎΠ³ΠΎ ΡΠ°ΡΠΏΡΠ΅Π΄Π΅Π»Π΅Π½ΠΈΡ ΡΡΠΊΠΎΡΡΠΈ ΠΈΠ·ΠΎΠ±ΡΠ°ΠΆΠ΅Π½ΠΈΡ ΠΎΡΠ°Π³Π° ΠΏΠΎΡΠ°ΠΆΠ΅Π½ΠΈΡ, ΠΊΠΎΡΠΎΡΡΠ΅ ΠΎΠΏΠΈΡΡΠ²Π°ΡΡΡΡ ΡΡΠ°ΡΠΈΡΡΠΈΡΠ΅ΡΠΊΠΈΠΌΠΈ ΡΠ΅ΠΊΡΡΡΡΠ½ΡΠΌΠΈ ΠΏΠ°ΡΠ°ΠΌΠ΅ΡΡΠ°ΠΌΠΈ.ΠΠ±ΡΡΠΆΠ΄Π΅Π½ΠΈΠ΅. ΠΠΎΠ»ΡΡΠ΅Π½ΠΎ ΠΏΠ΅ΡΠ²ΠΈΡΠ½ΠΎΠ΅ ΠΏΠΎΠ΄ΡΠ²Π΅ΡΠΆΠ΄Π΅Π½ΠΈΠ΅ Π²ΠΎΠ·ΠΌΠΎΠΆΠ½ΠΎΡΡΠΈ ΠΎΠ±ΡΠ΅ΠΊΡΠΈΠ²ΠΈΠ·Π°ΡΠΈΠΈ ΠΏΡΠΎΡΠ΅ΡΡΠ° Π΄ΠΈΠ°Π³Π½ΠΎΡΡΠΈΠΊΠΈ ΠΈ Π»Π΅ΡΠ΅Π½ΠΈΡ ΠΏΠΎ ΡΠΊΠ°Π·Π°Π½Π½ΡΠΌ ΡΡΠ°ΡΠΈΡΡΠΈΡΠ΅ΡΠΊΠΈΠΌ ΠΏΠ°ΡΠ°ΠΌΠ΅ΡΡΠ°ΠΌ Π’2 ΠΠ Π’-ΠΈΠ·ΠΎΠ±ΡΠ°ΠΆΠ΅Π½ΠΈΠΉ ΠΎΡΠ°Π³ΠΎΠ² ΠΏΠΎΡΠ°ΠΆΠ΅Π½ΠΈΡ.ΠΠ°ΠΊΠ»ΡΡΠ΅Π½ΠΈΠ΅. Π¦Π΅Π»ΡΡ Π΄Π°Π»ΡΠ½Π΅ΠΉΡΠΈΡ
ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΠΉ Π² Π΄Π°Π½Π½ΠΎΠΌ Π½Π°ΠΏΡΠ°Π²Π»Π΅Π½ΠΈΠΈ ΡΠ²Π»ΡΠ΅ΡΡΡ ΠΏΡΠΈΠΌΠ΅Π½Π΅Π½ΠΈΠ΅ ΡΠ°Π΄ΠΈΠΎΠΌΠΈΡΠ΅ΡΠΊΠΎΠ³ΠΎ Π°Π½Π°Π»ΠΈΠ·Π° Π΄Π»Ρ ΠΏΠ»Π°Π½ΠΈΡΠΎΠ²Π°Π½ΠΈΡ, ΠΌΠΎΠ½ΠΈΡΠΎΡΠΈΠ½Π³Π° Π»Π΅ΡΠ΅Π½ΠΈΡ Π³Π»ΠΈΠΎΠΌ Π²ΡΡΠΎΠΊΠΎΠΉ ΡΡΠ΅ΠΏΠ΅Π½ΠΈ Π·Π»ΠΎΠΊΠ°ΡΠ΅ΡΡΠ²Π΅Π½Π½ΠΎΡΡΠΈ, Π΄Π»Ρ ΠΏΡΠΎΠ³Π½ΠΎΠ·ΠΈΡΠΎΠ²Π°Π½ΠΈΡ ΠΈΡΡ
ΠΎΠ΄ΠΎΠ² Π·Π°Π±ΠΎΠ»Π΅Π²Π°Π½ΠΈΡ, Π° ΡΠ°ΠΊΠΆΠ΅ ΠΏΡΠ΅Π΄ΠΈΠΊΡΠΈΠ²Π½ΠΎΠ³ΠΎ Π°Π½Π°Π»ΠΈΠ·Π° ΠΎΡΠ²Π΅ΡΠ° Π½Π° ΠΊΠΎΠΌΠΏΠ»Π΅ΠΊΡΠ½ΠΎΠ΅ Π»Π΅ΡΠ΅Π½ΠΈΠ΅
The effect of the Mo/W ratio on the catalytic properties of alumina supported hydrotreating catalysts prepared from mixed SiMo6W6 and SiMo9W3 heteropolyacids
International audienceNew mixed H 4 [SiMo n W n-12 O 40 ] (n = 6 and 9) Keggin type heteropolyacids (HPAs) have been successfully synthesized, as confirmed by single-crystal XRD, Raman and IR spectroscopy analysis. The resulting polyoxometallates were used for preparation of hydrotreatment catalysts. Mo(W)/Al 2 O 3 catalysts were synthesized by incipient wetness impregnation of alumina support with water solutions of prepared mixed Keggin HPAs and corresponding counterparts based on mixture of monometallic H 4 [SiMo 12 O 40 ] and H 4 [SiW 12 O 40 ] HPAs. Oxidic catalysts were analyzed by Raman spectroscopy to determine the precursor structure after deposition. Catalysts in sulfided state were characterized by high-resolution transmission electron microscopy (HRTEM), high angle annular dark field imaging (HAADF) and X-ray photoelectron spectroscopy (XPS) and were tested in co-hydrotreating of dibenzothiophene (DBT) and naphthalene. The use of new mixed Keggin HPAs made it possible to obtain catalysts with mixed MoWS 2 active centers, which was confirmed by HAADF. Moreover, the Mo/(Mo + W) ratio has a direct effect on the structure of the active phase species. An ordered core-shell structure with Mo atoms in the core is maintained until the fraction of molybdenum in mixed MoW/Al 2 O 3 catalyst exceeds 50 %, where a more disordered structure is observed. Moreover, this Mo/(Mo + W) ratio of 0.5 is optimal to achieve a maximum catalytic activity. Indeed, the turnover frequencies (TOF) of the MoWS 2 edge centers with random atoms distribution in a cluster as in Mo 9 W 3 /Al 2 O 3 , was lower compared to that of Mo 6 W 6 /Al 2 O 3 with core-shell structure
Genesis of active phase in MoW/Al2O3 hydrotreating catalysts monitored by HAADF and in situ QEXAFS combined to MCR-ALS analysis
Alumina supported MoW hydrotreating catalyst was synthesized by using bimetallic H-4[SiMo3W9O40] Keggin heteropolyacid (HPA). Catalysts based on monometallic H-4[SiMo3W9O40] and H-4[SiMo3W9O40] and their mixture were also studied. Genesis of the active phase was studied during atmospheric gas sulfidation by H2S/H-2 of the catalysts by in-situ Quick X-ray absorption spectroscopy (XAS) and High-Angle Annular Dark-Field (HAADF) imaging. The combination of different chemometric tools such as Principal Component Analysis (PCA) and Multivariate Curve Resolution with Alternating Least Squares (MCR-ALS) allowed to determine the number of intermediate species, their chemical nature and concentration profiles during sulfidation. It was found that tungsten sulfidation using bimetallic HPA precursor started at lower temperature, compared to W sulfidation in the monometallic and in the mixture of monometallic HPA catalysts. Simultaneous sulfidation of Mo and W atoms in case of the bimetallic molecular precursor can govern the formation of mixed MoWS2 phase, which formation during activation was evidenced by HAADF