Sequential Growth of Magic-Size CdSe Nanocrystals†

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Extraction of Accurate Biomolecular Parameters from Single-Molecule Force Spectroscopy Experiments

The atomic force microscope (AFM) is able to manipulate biomolecules and their complexes with exquisite force sensitivity and distance resolution. This capability, complemented by theoretical models, has greatly improved our understanding of the determinants of mechanical strength in proteins and revealed the diverse effects of directional forces on the energy landscape of biomolecules. In unbinding experiments, the interacting partners are usually immobilized on their respective substrates via extensible linkers. These linkers affect both the force and contour length (Lc) of the complex at rupture. Surprisingly, while the former effect is well understood, the latter is largely neglected, leading to incorrect estimations of Lc, a parameter that is often used as evidence for the detection of specific interactions and remodeling events and for the inference of interaction regions. To address this problem, a model that predicts contour length measurements from single-molecule forced-dissociation experiments is presented that considers attachment position on the AFM tip, geometric effects, and polymer dynamics of the linkers. Modeled data are compared with measured contour length distributions from several different experimental systems, revealing that current methods underestimate contour lengths. The model enables nonspecific interactions to be identified unequivocally, allows accurate determination of Lc, and, by comparing experimental and modeled distributions, enables partial unfolding events before rupture to be identified unequivocally

Formation of colloidal alloy semiconductor CdTeSe magic-size clusters at room temperature

Alloy magic-size clusters (MSCs) are difficult to synthesize, in part because so little is known about how they form. Here, the authors produce single-ensemble alloy CdTeSe MSCs at room temperature by mixing prenucleation-stage solutions of CdTe and CdSe, uncovering a formation pathway that may extend to the synthesis of other alloy MSCs

Plan de mejora para la disminución de la rotación en Movich corporativo

En este proyecto de grado tiene como fin encontrar un plan de mejora para la disminución de la rotación en empresas del sector hotelero, para mejorar la productividad de los compañeros, motivándolos de manera extrínseca o intrínseca, dentro de dicho documento estará el software E-Learning para capacitar a los empleados y de esta manera, que pueda ejercer un plan de carrera al interior de la organización, motivación por medio de las distintas alianzas generadas, todo esto para que los empleados encuentren un clima laboral afable a sus necesidades.In this degree project aims to find an improvement plan for the decrease of rotation in companies in the hotel sector, to improve the productivity of peers, motivating them in an extrinsic or intrinsic way, within said document will be the E-Learning software to train employees and in this way, that can exercise a career plan within the organization, motivation through the various alliances generated, all this so that employees find a working environment friendly to their needs.Administrador (a) de EmpresasPregrad