Effect of Ankle Taping on Dynamic Balance and Perception of Stability

Purpose: The purpose of this study was to examine the actual and perceived effect of taping on dynamic stability. Methods: 21 physically active subjects [12 females (age = 20.33 ± 1.44 years, height = 165 ± 0.05 cm, mass = 68.76 ± 12.69 kg), and 9 males (age = 21.33 ± 1.66 years, height = 180 ± 0.10 cm, mass = 86.54 ± 9.46 kg)] participated in this study. Dynamic stability and perception of stability were assessed barefoot and with the ankle taped. The taped ankle condition used a standard preventive tape application including two anchors, three stirrups, close downs, horseshoes, two heel locks per side and two figures of eight. The Biodex Balance System SD was used to measure medial-lateral and anterior-posterior stability. Dynamic balance was assessed in a single leg stance during three 20-second trials at stability level 4. A 30-second rest period was provided between trials. Perception of stability was assessed using a 4-point Likert scale (1 = very unstable, 2 = unstable, 3 = stable, 4 = very stable) after each test session. Independent variables were counter-balanced to minimize the effects of fatigue associated with the testing procedures. A Repeated measures ANOVA was used to analyze the difference between barefoot and ankle tape for medial-lateral and anterior-posterior dynamic stability indices and perception of stability. All tests of significance were carried out at an alpha level = 0.05. The Bonferroni post hoc test was used for all paired comparisons. Results: Significant differences were not found for medial-lateral stability (Barefoot = 1.24 ± 0.63, Taped = 1.21 ± 0.72) nor anterior-posterior stability (Barefoot = 1.70 ± 1.07, Taped = 1.50 ± 0.89). Significant differences were found for perception of stability (Barefoot = 2.57 ± 0.60, Taped = 3.32 ± 0.67, p = 0.000). Conclusions: The use of ankle taping had no influence on dynamic stability measures in this study. Ankle taping did cause an increased perception of stability suggesting that ankle taping may have more of a placebo effect in uninjured ankles

Transforming Marketing Education of the Future: The Role of Intelligent Agent Technologies (IATs) in Enhancing Student Learning

This conceptual paper introduces IATs and discusses how such intelligent and interactive applications can translate into better education environment for marketing curriculum, particularly marketing research. We present a conceptual model based on extant literature. We present some initial test of our conceptual model of IAT usage in marketing education in a marketing research class

Exploring the Potential of Integral Field Spectroscopy Observing Extrasolar Planet Transits: Ground Based Observations of the Atmospheric Na in HD209458b

We explore the use of Integral Field Spectroscopy (IFS) to observe extrasolar planet transits. Although this technique should find its full potential in space observations (e.g. JWST, TPF), we have tested its basics with ground based time series observations of HD209458b obtained with WHT+INTEGRAL during a transit. For this analysis we used 5550 spectra, obtained in 150 exposures during a period of >7 hours. We found that IFS offers 3 fundamental advantages with respect to previously used methods. (i) It improves the effective S/N in photon limited observations by distributing the light coming from the star into the 2 dimensions of the detector. (ii) This type of IFS data allows to 'auto-calibrate' instrumental and background effects. (iii) Since the star image characteristics as well as its photometric properties are extracted from the same data-cube, it is possible to decorrelate photometric instabilities induced by PSF variations. These data have also allowed us to explore the accuracy limits of ground based 'relative' spectrophotometry. This was done using a photometric index that probes the NaD lines, for which we obtained a nominal 1-sigma error of ~1.0x10^-4. This result, based on observations of only 1 transit, indicates that this type of ground observation can constrain the characterization of the transmission spectrum of extrasolar planets. The present observations are compatible with no extra NaD depression during the transit. Though this result seems to be inconsistent with the recently reported HST-STIS findings we point out its limited statistical meaning: the results disagree within 1-sigma, but agree within 2-sigma. We also give some recommenda-tions to instrument developers in order to enhance the efficiency of the method.Comment: 15 pages, 2 tables, 10 figures. To appear in PASP (January 2006

New Models for Wolf-Rayet and O Star Populations in Young Starbursts

Using the latest stellar evolution models, theoretical stellar spectra, and a compilation of observed emission line strengths from Wolf-Rayet (WR) stars, we construct evolutionary synthesis models for young starbursts. We explicitly distinguish between the various WR subtypes (WN, WC, WO), and we treat O and Of stars separately. We provide detailed predictions of UV and optical emission line strengths for both the WR stellar lines and the major nebular hydrogen and helium emission lines, as a function of several input parameters related to the starburst episode. We also derive the theoretical frequency of WR-rich starbursts. We then discuss: nebular HeII 4686 emission, the contribution of WR stars to broad Balmer line emission, techniques used to derive the WR and O star content from integrated spectra, and explore the implications of the formation of WR stars through mass transfer in close binary systems in instantaneous bursts. The observational features predicted by our models allow a detailed quantitative determination of the massive star population in a starburst region (particularly in so-called "WR galaxies") from its integrated spectrum and provide a means of deriving the burst properties (e.g., duration, age) and the parameters of the initial mass function of young starbursts. (Abridged abstract)Comment: Accepted by ApJ Supplements. LaTeX using aasmp4, psfigs macros. 49 pages including 23 figures. Paper (full, or text/figures separated) and detailed model results available at http://www.stsci.edu/ftp/science/starburst/sv97.htm

The prototype colliding-wind pinwheel WR 104

Results from the most extensive study of the time-evolving dust structure around the prototype "Pinwheel" nebula WR 104 are presented. Encompassing 11 epochs in three near-infrared filter bandpasses, a homogeneous imaging data set spanning more than 6 years (or 10 orbits) is presented. Data were obtained from the highly successful Keck Aperture Masking Experiment, which can recover high fidelity images at extremely high angular resolutions, revealing the geometry of the plume with unprecedented precision. Inferred properties for the (unresolved) underlying binary and wind system are orbital period 241.5 +/- 0.5 days and angular outflow velocity of 0.28 +/- 0.02 mas/day. An optically thin cavity of angular size 13.3 +/- 1.4 mas was found to lie between the central binary and the onset of the spiral dust plume. Rotational motion of the wind system induced by the binary orbit is found to have important ramifications: entanglement of the winds results in strong shock activity far downstream from the nose of the bowshock. The far greater fraction of the winds participating in the collision may play a key role in gas compression and the nucleation of dust at large radii from the central binary and shock stagnation point. Investigation of the effects of radiative braking pointed towards significant modifications of the simple hydrostatic colliding wind geometry, extending the relevance of this phenomena to wider binary systems than previously considered. Limits placed on the maximum allowed orbital eccentricity of e < 0.06 argue strongly for a prehistory of tidal circularization in this system. Finally we discuss the implications of Earth's polar (i < 16 deg) vantage point onto a system likely to host supernova explosions at future epochs.Comment: 35 pages, 8 figures, Accepted for publication in Astrophysical Journa

Genome-wide Association Meta-analysis of Childhood and Adolescent Internalizing Symptoms

Objective: To investigate the genetic architecture of internalizing symptoms in childhood and adolescence. Method: In 22 cohorts, multiple univariate genome-wide association studies (GWASs) were performed using repeated assessments of internalizing symptoms, in a total of 64,561 children and adolescents between 3 and 18 years of age. Results were aggregated in meta-analyses that accounted for sample overlap, first using all available data, and then using subsets of measurements grouped by rater, age, and instrument. Results: The meta-analysis of overall internalizing symptoms (INToverall) detected no genome-wide significant hits and showed low single nucleotide polymorphism (SNP) heritability (1.66%, 95% CI = 0.84-2.48%, n(effective) = 132,260). Stratified analyses indicated rater-based heterogeneity in genetic effects, with self-reported internalizing symptoms showing the highest heritability (5.63%, 95% CI = 3.08%-8.18%). The contribution of additive genetic effects on internalizing symptoms appeared to be stable over age, with overlapping estimates of SNP heritability from early childhood to adolescence. Genetic correlations were observed with adult anxiety, depression, and the well-being spectrum (vertical bar r(g)vertical bar > 0.70), as well as with insomnia, loneliness, attention-deficit/hyperactivity disorder, autism, and childhood aggression (range vertical bar r(g)vertical bar = 0.42-0.60), whereas there were no robust associations with schizophrenia, bipolar disorder, obsessive-compulsive disorder, or anorexia nervosa. Conclusion: Genetic correlations indicate that childhood and adolescent internalizing symptoms share substantial genetic vulnerabilities with adult internalizing disorders and other childhood psychiatric traits, which could partially explain both the persistence of internalizing symptoms over time and the high comorbidity among childhood psychiatric traits. Reducing phenotypic heterogeneity in childhood samples will be key in paving the way to future GWAS success.Peer reviewe

The Early Growth Genetics (EGG) and EArly Genetics and Lifecourse Epidemiology (EAGLE) consortia : design, results and future prospects

The impact of many unfavorable childhood traits or diseases, such as low birth weight and mental disorders, is not limited to childhood and adolescence, as they are also associated with poor outcomes in adulthood, such as cardiovascular disease. Insight into the genetic etiology of childhood and adolescent traits and disorders may therefore provide new perspectives, not only on how to improve wellbeing during childhood, but also how to prevent later adverse outcomes. To achieve the sample sizes required for genetic research, the Early Growth Genetics (EGG) and EArly Genetics and Lifecourse Epidemiology (EAGLE) consortia were established. The majority of the participating cohorts are longitudinal population-based samples, but other cohorts with data on early childhood phenotypes are also involved. Cohorts often have a broad focus and collect(ed) data on various somatic and psychiatric traits as well as environmental factors. Genetic variants have been successfully identified for multiple traits, for example, birth weight, atopic dermatitis, childhood BMI, allergic sensitization, and pubertal growth. Furthermore, the results have shown that genetic factors also partly underlie the association with adult traits. As sample sizes are still increasing, it is expected that future analyses will identify additional variants. This, in combination with the development of innovative statistical methods, will provide detailed insight on the mechanisms underlying the transition from childhood to adult disorders. Both consortia welcome new collaborations. Policies and contact details are available from the corresponding authors of this manuscript and/or the consortium websites.Peer reviewe

Consensus statements and recommendations from the ESO-Karolinska Stroke Update Conference, Stockholm 11-13 November 2018

The purpose of the European Stroke Organisation-Karolinska Stroke Update Conference is to provide updates on recent stroke therapy research and to give an opportunity for the participants to discuss how these results may be implemented into clinical routine. The meeting started 22 years ago as Karolinska Stroke Update, but since 2014 it is a joint conference with European Stroke Organisation. Importantly, it provides a platform for discussion on the European Stroke Organisation guidelines process and on recommendations to the European Stroke Organisation guidelines committee on specific topics. By this, it adds a direct influence from stroke professionals otherwise not involved in committees and work groups on the guideline procedure. The discussions at the conference may also inspire new guidelines when motivated. The topics raised at the meeting are selected by the scientific programme committee mainly based on recent important scientific publications. This year's European Stroke Organisation-Karolinska Stroke Update Meeting was held in Stockholm on 11-13 November 2018. There were 11 scientific sessions discussed in the meeting including two short sessions. Each session except the short sessions produced a consensus statement (Full version with background, issues, conclusions and references are published as web-material and at and ) and recommendations which were prepared by a writing committee consisting of session chair(s), scientific secretary and speakers. These statements were presented to the 250 participants of the meeting. In the open meeting, general participants commented on the consensus statement and recommendations and the final document were adjusted based on the discussion from the general participants Recommendations (grade of evidence) were graded according to the 1998 Karolinska Stroke Update meeting with regard to the strength of evidence. Grade A Evidence: Strong support from randomised controlled trials and statistical reviews (at least one randomised controlled trial plus one statistical review). Grade B Evidence: Support from randomised controlled trials and statistical reviews (one randomised controlled trial or one statistical review). Grade C Evidence: No reasonable support from randomised controlled trials, recommendations based on small randomised and/or non-randomised controlled trials evidence.Peer reviewe