1,227 research outputs found
Comparison of Different Finite Element Models for the Transient Dynamic Analysis of Laminated Glass for Structural Applications
Commercial laminated glass is usually composed of two glass layers and an interlayer of PVB. The viscoelastic behaviour of the PVB layer has to be taken into account when dealing with dynamic loads. This paper shows different Finite Element (FE) models developed to characterize laminated glass. Results are contrasted with data from different reference test cases. First, a quasi-static test is reproduced with a 2d model through a transient analysis. In addition, flexural modes of vibration in a free-free test configuration have been analysed using 2d as well as 3d FE models. Apart from using transient analysis in order to simulate the dynamic behaviour of laminated glass, an iterative procedure has been employed which permits to identify the correct value of the shear modulus of the PVB layer for each mode in an eigenvalue analysis
Profilul aromatic bazat pevalorile activităţii odorante şi pe seriilor aromatice în vinurile roşii supuse diferitelor tipuri de maturare cuchips-uri din stejar american şi francez
Use of oak wood during the process of wine ageing is an ancient and common practice in most of the world’s wine producing regions. In this study, the contribution of a chemical compound to the aroma of a wine was evaluated by determining the odour activity value (OAV). OAV,was calculated as the ratio between the concentration of an individual compound and the perception threshold reported in the literature. The analytical aroma profile was established by using the OAVs of each odorant compounds exhibiting similar odor descriptor grouped in an aroma series. Majoraroma contributors in the Feteascăneagră wine aged with American and French oak chips were the fruity, chemistry, fatty and floral series followed by the woody series. Red wines analyzed at 1.5 and 3 months present similar behaviour,howeverwines aged with 5 g/L of French oak chips distinguished from the rest when using PC
Evaluation of Aroma Compounds in the Process of Wine Ageing with Oak Chips
Many modern alcoholic beverages are subjected to ageing processes during which
compounds extracted from wood contribute decisively to the overall beverage character. Wines
represent a perfect example of beverage in which ageing is a crucial technological manufacturing
step. During winemaking, producers accelerate chemical changes in wine composition by traditional
and alternative methods, such as the use of oak wood barrels and/or oak wood chips. Our research
aimed to investigate the overall volatile composition and sensory quality of red wines aged for two
timeframes, namely, 1.5 and 3 months, and with two technological variants, i.e., American and French
oak wood chips. Red grapes from the Feteasca neagra (Vitis vinifera) variety were harvested from a
vineyard in the North-East region of Romania. Stir bar sorptive extraction and gas chromatography
coupled with mass spectrometry (SBSE–GC–MS) was used to extract minor aromas present in wine
samples. The results showed clear di erences between wines treated with American and French
oak chips. Furthermore, ageing for 3 months increased the concentration of cis-whiskey lactone and
guaiacol in American oak-treated wine samples. For wines aged with French oak chips, we observed
higher concentrations of furfural, 5-methylfurfural, 4-vinylguaiacol, and trans-whiskey lactone. The
increased presence of chemical compounds in wine aged with French oak chips generated prominent
smoky, licorice, and toasty aromas, whereas in wines aged with American oak chips, notes of vanilla,
toasty, and cacao aromas were noticed. Moreover, red wines aged with American and French oak chips
were discriminated by chemometric analysis, which confirmed the evolution of aroma compounds
Hyaluronic acid reduces inflammation and crevicular fluid IL-1β concentrations in peri-implantitis: a randomized controlled clinical trial
Trial Registration: ClinicalTrials.gov Identifier: NCT03157193The authors are grateful to Richard Davies for editorial assistance.This study was supported by Ricerfarma srl. (Milan, Italy) in collaboration with Research Group #CTS 583 (Junta de Andalucia, Spain) (reference: OTRI-3300). The authors declare that they have no conflict of interest, either directly or indirectly, with any of the companies or products listed in the study.Purpose
This study investigated the effects of hyaluronic acid (HA) on peri-implant clinical variables and crevicular concentrations of the proinflammatory biomarkers interleukin (IL)-1β and tumor necrosis factor (TNF)-α in patients with peri-implantitis.
Methods
A randomized controlled trial was conducted in peri-implantitis patients. Patients were randomized to receive a 0.8% HA gel (test group), an excipient-based gel (control group 1), or no gel (control group 2). Clinical periodontal variables and marginal bone loss after 0, 45, and 90 days of treatment were assessed. IL-1β and TNF-α levels in crevicular fluid were measured by enzyme-linked immunosorbent assays at baseline and after 45 days of treatment. Clustering analysis was performed, considering the possibility of multiple implants in a single patient.
Results
Sixty-one patients with 100 dental implants were assigned to the test group, control group 1, or control group 2. Probing pocket depth (PPD) was significantly lower in the test group than in both control groups at 45 days (control 1: 95% CI, −1.66, −0.40 mm; control 2: 95% CI, −1.07, −0.01 mm) and 90 days (control 1: 95% CI, −1.72, −0.54 mm; control 2: 95% CI, −1.13, −0.15 mm). There was a trend towards less bleeding on probing in the test group than in control group 2 at 90 days (P=0.07). Implants with a PPD ≥5 mm showed higher levels of IL-1β in the control group 2 at 45 days than in the test group (P=0.04).
Conclusions
This study demonstrates for the first time that the topical application of a HA gel in the peri-implant pocket and around implants with peri-implantitis may reduce inflammation and crevicular fluid IL-1β levels.Ricerfarma srl. (Milan, Italy)Junta de Andalucia
CTS 583European Commission OTRI-330
First-line treatment in lymphomatoid papulosis: a retrospective multicentre study
Background: Data regarding response to treatment in lymphomatoid papulosis (LyP) are scarce. Aim: To assess the daily clinical practice approach to LyP and the response to first-line treatments. Methods: This was a retrospective study enrolling 252 patients with LyP. Results: Topical steroids, methotrexate and phototherapy were the most common first-line treatments, prescribed for 35%, 20% and 14% of the patients, respectively. Complete response (CR) was achieved in 48% of treated patients. Eczematous lesions significantly increased relative risk (RR) of not achieving CR (RR = 1.76; 95% CI 1.16-2.11). Overall median time to CR was 10 months (95% CI 6-13 months), and 78% of complete responders showed cutaneous relapse; both results were similar for all treatment groups (P > 0.05). Overall estimated median disease-free survival (DFS) was 11 months (95% CI 9-13 months) but DFS for patients treated with phototherapy was 23 months (95% CI 10-36 months; P < 0.03). Having the Type A LyP variant (RR = 2.04; 95% CI 0.96-4.30) and receiving a first-line treatment other than phototherapy (RR = 5.33; 95% CI 0.84-33.89) were significantly associated with cutaneous early relapse. Of the 252 patients, 31 (13%) had associated mycosis fungoides unrelated to therapeutic approach, type of LyP or T-cell receptor clonality. Conclusions: Current epidemiological, clinical and pathological data support previous results. Topical steroids, phototherapy and methotrexate are the most frequently prescribed first-line treatments. Although CR and cutaneous relapse rates do not differ between them, phototherapy achieves a longer DFS. Presence of Type A LyP and use of topical steroid or methotrexate were associated with an increased risk of early relapse
Centrality dependence of charged particle production at large transverse momentum in Pb-Pb collisions at TeV
The inclusive transverse momentum () distributions of primary
charged particles are measured in the pseudo-rapidity range as a
function of event centrality in Pb-Pb collisions at
TeV with ALICE at the LHC. The data are presented in the range
GeV/ for nine centrality intervals from 70-80% to 0-5%.
The Pb-Pb spectra are presented in terms of the nuclear modification factor
using a pp reference spectrum measured at the same collision
energy. We observe that the suppression of high- particles strongly
depends on event centrality. In central collisions (0-5%) the yield is most
suppressed with at -7 GeV/. Above
GeV/, there is a significant rise in the nuclear modification
factor, which reaches for GeV/. In
peripheral collisions (70-80%), the suppression is weaker with almost independently of . The measured nuclear
modification factors are compared to other measurements and model calculations.Comment: 17 pages, 4 captioned figures, 2 tables, authors from page 12,
published version, figures at
http://aliceinfo.cern.ch/ArtSubmission/node/284
Anisotropic flow of charged hadrons, pions and (anti-)protons measured at high transverse momentum in Pb-Pb collisions at TeV
The elliptic, , triangular, , and quadrangular, , azimuthal
anisotropic flow coefficients are measured for unidentified charged particles,
pions and (anti-)protons in Pb-Pb collisions at TeV
with the ALICE detector at the Large Hadron Collider. Results obtained with the
event plane and four-particle cumulant methods are reported for the
pseudo-rapidity range at different collision centralities and as a
function of transverse momentum, , out to GeV/.
The observed non-zero elliptic and triangular flow depends only weakly on
transverse momentum for GeV/. The small dependence
of the difference between elliptic flow results obtained from the event plane
and four-particle cumulant methods suggests a common origin of flow
fluctuations up to GeV/. The magnitude of the (anti-)proton
elliptic and triangular flow is larger than that of pions out to at least
GeV/ indicating that the particle type dependence persists out
to high .Comment: 16 pages, 5 captioned figures, authors from page 11, published
version, figures at http://aliceinfo.cern.ch/ArtSubmission/node/186
Charge separation relative to the reaction plane in Pb-Pb collisions at TeV
Measurements of charge dependent azimuthal correlations with the ALICE
detector at the LHC are reported for Pb-Pb collisions at TeV. Two- and three-particle charge-dependent azimuthal correlations in
the pseudo-rapidity range are presented as a function of the
collision centrality, particle separation in pseudo-rapidity, and transverse
momentum. A clear signal compatible with a charge-dependent separation relative
to the reaction plane is observed, which shows little or no collision energy
dependence when compared to measurements at RHIC energies. This provides a new
insight for understanding the nature of the charge dependent azimuthal
correlations observed at RHIC and LHC energies.Comment: 12 pages, 3 captioned figures, authors from page 2 to 6, published
version, figures at http://aliceinfo.cern.ch/ArtSubmission/node/286
A note on comonotonicity and positivity of the control components of decoupled quadratic FBSDE
In this small note we are concerned with the solution of Forward-Backward
Stochastic Differential Equations (FBSDE) with drivers that grow quadratically
in the control component (quadratic growth FBSDE or qgFBSDE). The main theorem
is a comparison result that allows comparing componentwise the signs of the
control processes of two different qgFBSDE. As a byproduct one obtains
conditions that allow establishing the positivity of the control process.Comment: accepted for publicatio
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