The medieval Cemetery surrounding the Chapel of St. Anne in Gornji Kosinj

Hrvatski restauratorski zavod je tijekom listopada 2020. godine obavio probna arheološka istraživanja na prostoru oko kapele sv. Ane u Gornjem Kosinju. Sukladno projektnoj dokumentaciji istraženo je pet sondi i ukupna površina od 70 m2. Ispred pročelja kapele i uz njezin južni zid pronađen je velik broj kosturnih ostataka pokojnika. Kako je groblje korišteno tijekom nekoliko stoljeća, grobovi su uglavnom poremećeni i većina je kostiju dislocirana. Prema pokretnim nalazima, kalibriranim radiokarbonskim datumima i stratigrafiji 23 groba možemo datirati u razdoblje od kraja 10./početka 11. do kraja 14. stoljeća. Nalazi su pronađeni u osam grobova: naušnice, karičice i prstenovi u ženskim te dijelovi pojasa i obuće, ostruga i kositreni kalež u muškim grobovima. Većina ukopa prati orijentaciju današnje kapele te se može pretpostaviti postojanje sakralne građevine na njezinome mjestu već u 11. stoljeću. Samo je jedan grob datiran u razdoblje poslije 1696. godine, a nalazi se ispred pročelja kapele.In October 2020, the Croatian Conservation Institute carried out archaeological trial excavations in the area surrounding the chapel of St. Anne in Gornji Kosinj, which, in accordance with the project documentation, included the exploration of five trenches and covered a total area of 70 m2. The research yielded a significant number of skeletal remains, which were discovered in front of the chapel’s façade and along its southern wall. Since the cemetery has been in use over several centuries, most graves were disturbed, resulting in the displacement of the majority of bones. Based on movable finds, calibrated radiocarbon dates and stratigraphy, it is possible to date 23 graves to the period from the late 10th/early 11th to the late 14th century. Finds were discovered in eight graves, which contained earrings, circlets and rings in female graves, as well as parts of belts and footwear, spurs and a tin chalice in male graves. Most burials follow the orientation of the present chapel, indicating the presence of a sacred structure on its site as early as the 11th century. Only one grave dates back to the period after 1696, which is located in front of the façade of the chapel

Digital volunteer networks and humanitarian crisis reporting

Digital technologies and big data are rapidly transforming humanitarian crisis response and changing the traditional roles and powers of its actors. This article looks at a particular aspect of this transformation – the appearance of digital volunteer networks – and explores their potential to act as a new source for media coverage, in addition to their already established role as emergency response supporters. I argue that digital humanitarians can offer a unique combination of speed and safe access, while escaping some of the traditional constraints of the aid-media relationship and exceeding the conventional conceptualizations of citizen journalism. Journalists can find both challenges and opportunities in the environment where multiple crisis actors are assuming some of the media roles. The article draws on interviews with humanitarian organizations, journalists, and digital volunteer networks about their understanding of digital humanitarian communication and its significance for media coverage of crises

Povratak u prošlost: bakreno doba u sjevernoj Hrvatskoj

Knjiga Povratak u prošlost. Bakreno doba u sjevernoj Hrvatskoj nastala je u sklopu istoimene izložbe postavljene u Arheološkom muzeju u Zagrebu u suradnji s Odsjekom za arheologiju Filozofskog fakulteta u Zagrebu i Arheološkim muzejom u Osijeku. Publikacija sadrži 16 tekstova koje pokrivaju različite bakrenodobne teme kroz razdoblje od približno 2000 godina – od načina života i organizacije naselja, izrade i upotrebe predmeta od različitih materijala, iskorištavanja različitih sirovina do zagrobnog života. Osim područja sjeverne Hrvatske u tekstovima je naglašena i međuovisnsot i komunikacija s ostalim dijelovima europskog kontinenta.Knjiga Povratak u prošlost. Bakreno doba u sjevernoj Hrvatskoj nastala je u sklopu istoimene izložbe postavljene u Arheološkom muzeju u Zagrebu u suradnji s Odsjekom za arheologiju Filozofskog fakulteta u Zagrebu i Arheološkim muzejom u Osijeku. Publikacija sadrži 16 tekstova koje pokrivaju različite bakrenodobne teme kroz razdoblje od približno 2000 godina – od načina života i organizacije naselja, izrade i upotrebe predmeta od različitih materijala, iskorištavanja različitih sirovina do zagrobnog života. Osim područja sjeverne Hrvatske u tekstovima je naglašena i međuovisnsot i komunikacija s ostalim dijelovima europskog kontinenta

A 32-society investigation of the influence of perceived economic inequality on social class stereotyping

International audienceThere is a growing body of work suggesting that social class stereotypes are amplified when people perceive higher levels of economic inequality-that is, the wealthy are perceived as more competent and assertive and the poor as more incompetent and unassertive. The present study tested this prediction in 32 societies and also examines the role of wealth-based categorization in explaining this relationship. We found that people who perceived higher economic inequality were indeed more likely to consider wealth as a meaningful basis for categorization. Unexpectedly, however, higher levels of perceived inequality were associated with perceiving the wealthy as less competent and assertive and the poor as more competent and assertive. Unpacking this further, exploratory analyses showed that the observed tendency to stereotype the wealthy negatively only emerged in societies with lower social mobility and democracy and higher corruption. This points to the importance of understanding how socio-structural features that co-occur with economic inequality may shape perceptions of the wealthy and the poor

Flattening filter-free accelerators: a report from the AAPM Therapy Emerging Technology Assessment Work Group.

This report describes the current state of flattening filter-free (FFF) radiotherapy beams implemented on conventional linear accelerators, and is aimed primarily at practicing medical physicists. The Therapy Emerging Technology Assessment Work Group of the American Association of Physicists in Medicine (AAPM) formed a writing group to assess FFF technology. The published literature on FFF technology was reviewed, along with technical specifications provided by vendors. Based on this information, supplemented by the clinical experience of the group members, consensus guidelines and recommendations for implementation of FFF technology were developed. Areas in need of further investigation were identified. Removing the flattening filter increases beam intensity, especially near the central axis. Increased intensity reduces treatment time, especially for high-dose stereotactic radiotherapy/radiosurgery (SRT/SRS). Furthermore, removing the flattening filter reduces out-of-field dose and improves beam modeling accuracy. FFF beams are advantageous for small field (e.g., SRS) treatments and are appropriate for intensity-modulated radiotherapy (IMRT). For conventional 3D radiotherapy of large targets, FFF beams may be disadvantageous compared to flattened beams because of the heterogeneity of FFF beam across the target (unless modulation is employed). For any application, the nonflat beam characteristics and substantially higher dose rates require consideration during the commissioning and quality assurance processes relative to flattened beams, and the appropriate clinical use of the technology needs to be identified. Consideration also needs to be given to these unique characteristics when undertaking facility planning. Several areas still warrant further research and development. Recommendations pertinent to FFF technology, including acceptance testing, commissioning, quality assurance, radiation safety, and facility planning, are presented. Examples of clinical applications are provided. Several of the areas in which future research and development are needed are also indicated

Stromal Down-Regulation of Macrophage CD4/CCR5 Expression and NF-κB Activation Mediates HIV-1 Non-Permissiveness in Intestinal Macrophages

Tissue macrophages are derived exclusively from blood monocytes, which as monocyte-derived macrophages support HIV-1 replication. However, among human tissue macrophages only intestinal macrophages are non-permissive to HIV-1, suggesting that the unique microenvironment in human intestinal mucosa renders lamina propria macrophages non-permissive to HIV-1. We investigated this hypothesis using blood monocytes and intestinal extracellular matrix (stroma)-conditioned media (S-CM) to model the exposure of newly recruited monocytes and resident macrophages to lamina propria stroma, where the cells take up residence in the intestinal mucosa. Exposure of monocytes to S-CM blocked up-regulation of CD4 and CCR5 expression during monocyte differentiation into macrophages and inhibited productive HIV-1 infection in differentiated macrophages. Importantly, exposure of monocyte-derived macrophages simultaneously to S-CM and HIV-1 also inhibited viral replication, and sorted CD4+ intestinal macrophages, a proportion of which expressed CCR5+, did not support HIV-1 replication, indicating that the non-permissiveness to HIV-1 was not due to reduced receptor expression alone. Consistent with this conclusion, S-CM also potently inhibited replication of HIV-1 pseudotyped with vesicular stomatitis virus glycoprotein, which provides CD4/CCR5-independent entry. Neutralization of TGF-β in S-CM and recombinant TGF-β studies showed that stromal TGF-β inhibited macrophage nuclear translocation of NF-κB and HIV-1 replication. Thus, the profound inability of intestinal macrophages to support productive HIV-1 infection is likely the consequence of microenvironmental down-regulation of macrophage HIV-1 receptor/coreceptor expression and NF-κB activation

Measurement of the top quark forward-backward production asymmetry and the anomalous chromoelectric and chromomagnetic moments in pp collisions at √s = 13 TeV

Abstract The parton-level top quark (t) forward-backward asymmetry and the anomalous chromoelectric (d̂ t) and chromomagnetic (μ̂ t) moments have been measured using LHC pp collisions at a center-of-mass energy of 13 TeV, collected in the CMS detector in a data sample corresponding to an integrated luminosity of 35.9 fb−1. The linearized variable AFB(1) is used to approximate the asymmetry. Candidate t t ¯ events decaying to a muon or electron and jets in final states with low and high Lorentz boosts are selected and reconstructed using a fit of the kinematic distributions of the decay products to those expected for t t ¯ final states. The values found for the parameters are AFB(1)=0.048−0.087+0.095(stat)−0.029+0.020(syst),μ̂t=−0.024−0.009+0.013(stat)−0.011+0.016(syst), and a limit is placed on the magnitude of | d̂ t| < 0.03 at 95% confidence level. [Figure not available: see fulltext.

MUSiC : a model-unspecific search for new physics in proton-proton collisions at root s=13TeV

Results of the Model Unspecific Search in CMS (MUSiC), using proton-proton collision data recorded at the LHC at a centre-of-mass energy of 13 TeV, corresponding to an integrated luminosity of 35.9 fb(-1), are presented. The MUSiC analysis searches for anomalies that could be signatures of physics beyond the standard model. The analysis is based on the comparison of observed data with the standard model prediction, as determined from simulation, in several hundred final states and multiple kinematic distributions. Events containing at least one electron or muon are classified based on their final state topology, and an automated search algorithm surveys the observed data for deviations from the prediction. The sensitivity of the search is validated using multiple methods. No significant deviations from the predictions have been observed. For a wide range of final state topologies, agreement is found between the data and the standard model simulation. This analysis complements dedicated search analyses by significantly expanding the range of final states covered using a model independent approach with the largest data set to date to probe phase space regions beyond the reach of previous general searches.Peer reviewe

Search for new particles in events with energetic jets and large missing transverse momentum in proton-proton collisions at root s=13 TeV

A search is presented for new particles produced at the LHC in proton-proton collisions at root s = 13 TeV, using events with energetic jets and large missing transverse momentum. The analysis is based on a data sample corresponding to an integrated luminosity of 101 fb(-1), collected in 2017-2018 with the CMS detector. Machine learning techniques are used to define separate categories for events with narrow jets from initial-state radiation and events with large-radius jets consistent with a hadronic decay of a W or Z boson. A statistical combination is made with an earlier search based on a data sample of 36 fb(-1), collected in 2016. No significant excess of events is observed with respect to the standard model background expectation determined from control samples in data. The results are interpreted in terms of limits on the branching fraction of an invisible decay of the Higgs boson, as well as constraints on simplified models of dark matter, on first-generation scalar leptoquarks decaying to quarks and neutrinos, and on models with large extra dimensions. Several of the new limits, specifically for spin-1 dark matter mediators, pseudoscalar mediators, colored mediators, and leptoquarks, are the most restrictive to date.Peer reviewe

Measurement of prompt open-charm production cross sections in proton-proton collisions at root s=13 TeV

The production cross sections for prompt open-charm mesons in proton-proton collisions at a center-of-mass energy of 13TeV are reported. The measurement is performed using a data sample collected by the CMS experiment corresponding to an integrated luminosity of 29 nb(-1). The differential production cross sections of the D*(+/-), D-+/-, and D-0 ((D) over bar (0)) mesons are presented in ranges of transverse momentum and pseudorapidity 4 < p(T) < 100 GeV and vertical bar eta vertical bar < 2.1, respectively. The results are compared to several theoretical calculations and to previous measurements.Peer reviewe