The ALPINE-ALMA [C ii] Survey: Size of Individual Star-forming Galaxies at z = 4-6 and Their Extended Halo Structure

We present the physical extent of [CII] 158um line-emitting gas from 46 star-forming galaxies at z=4-6 from the ALMA Large Program to INvestigate CII at Early Times (ALPINE). Using exponential profile fits, we measure the effective radius of the [CII] line (r_e,[CII]) for individual galaxies and compare them with the rest-frame ultra-violet (UV) continuum (r_e,UV) from Hubble Space Telescope images. The effective radius r_e,[CII] exceeds r_e,UV by factors of ~2-3 and the ratio of r_e,[CII]/r_e,UV increases as a function of M_star. We do not find strong evidence that [CII] line, the rest-frame UV, and FIR continuum are always displaced over ~ 1-kpc scale from each other. We identify 30% of isolated ALPINE sources as having an extended [CII] component over 10-kpc scales detected at 4.1$\sigma$-10.9$\sigma$ beyond the size of rest-frame UV and far-infrared (FIR) continuum. One object has tentative rotating features up to ~10-kpc, where the 3D model fit shows the rotating [CII]-gas disk spread over 4 times larger than the rest-frame UV-emitting region. Galaxies with the extended [CII] line structure have high star-formation rate (SFR), stellar mass (M_star), low Lya equivalent-width, and more blue-shifted (red-shifted) rest-frame UV metal absorption (Lya line), as compared to galaxies without such extended [CII] structures. Although we cannot rule out the possibility that a selection bias towards luminous objects may be responsible for such trends, the star-formation driven outflow also explains all these trends. Deeper observations are essential to test whether the extended [CII] line structures are ubiquitous to high-z star-forming galaxies.ERC STF

Impact of clinical phenotypes on management and outcomes in European atrial fibrillation patients: a report from the ESC-EHRA EURObservational Research Programme in AF (EORP-AF) General Long-Term Registry

Background: Epidemiological studies in atrial fibrillation (AF) illustrate that clinical complexity increase the risk of major adverse outcomes. We aimed to describe European AF patients\u2019 clinical phenotypes and analyse the differential clinical course. Methods: We performed a hierarchical cluster analysis based on Ward\u2019s Method and Squared Euclidean Distance using 22 clinical binary variables, identifying the optimal number of clusters. We investigated differences in clinical management, use of healthcare resources and outcomes in a cohort of European AF patients from a Europe-wide observational registry. Results: A total of 9363 were available for this analysis. We identified three clusters: Cluster 1 (n = 3634; 38.8%) characterized by older patients and prevalent non-cardiac comorbidities; Cluster 2 (n = 2774; 29.6%) characterized by younger patients with low prevalence of comorbidities; Cluster 3 (n = 2955;31.6%) characterized by patients\u2019 prevalent cardiovascular risk factors/comorbidities. Over a mean follow-up of 22.5 months, Cluster 3 had the highest rate of cardiovascular events, all-cause death, and the composite outcome (combining the previous two) compared to Cluster 1 and Cluster 2 (all P <.001). An adjusted Cox regression showed that compared to Cluster 2, Cluster 3 (hazard ratio (HR) 2.87, 95% confidence interval (CI) 2.27\u20133.62; HR 3.42, 95%CI 2.72\u20134.31; HR 2.79, 95%CI 2.32\u20133.35), and Cluster 1 (HR 1.88, 95%CI 1.48\u20132.38; HR 2.50, 95%CI 1.98\u20133.15; HR 2.09, 95%CI 1.74\u20132.51) reported a higher risk for the three outcomes respectively. Conclusions: In European AF patients, three main clusters were identified, differentiated by differential presence of comorbidities. Both non-cardiac and cardiac comorbidities clusters were found to be associated with an increased risk of major adverse outcomes

Higher harmonic anisotropic flow measurements of charged particles in Pb-Pb collisions at 2.76 TeV

We report on the first measurement of the triangular $v_3$, quadrangular $v_4$, and pentagonal $v_5$ charged particle flow in Pb-Pb collisions at 2.76 TeV measured with the ALICE detector at the CERN Large Hadron Collider. We show that the triangular flow can be described in terms of the initial spatial anisotropy and its fluctuations, which provides strong constraints on its origin. In the most central events, where the elliptic flow $v_2$ and $v_3$ have similar magnitude, a double peaked structure in the two-particle azimuthal correlations is observed, which is often interpreted as a Mach cone response to fast partons. We show that this structure can be naturally explained from the measured anisotropic flow Fourier coefficients.Comment: 10 pages, 4 figures, published version, figures at http://aliceinfo.cern.ch/ArtSubmission/node/387

The ALPINE-ALMA [C ii] Survey: Size of Individual Star-forming Galaxies at z = 4-6 and Their Extended Halo Structure

We present the physical extent of [C ii] 158 \u3bcm line-emitting gas from 46 star-forming galaxies at z = 4-6 from the ALMA Large Program to INvestigate C ii at Early Times (ALPINE). Using exponential profile fits, we measure the effective radius of the [C ii] line () for individual galaxies and compare them with the rest-frame ultraviolet (UV) continuum () from Hubble Space Telescope images. The effective radius exceeds by factors of 3c2-3, and the ratio of increases as a function of M star. We do not find strong evidence that the [C ii] line, rest-frame UV, and far-infrared (FIR) continuum are always displaced over 431 kpc scale from each other. We identify 30% of isolated ALPINE sources as having an extended [C ii] component over 10 kpc scales detected at 4.1\u3c3-10.9\u3c3 beyond the size of rest-frame UV and FIR continuum. One object has tentative rotating features up to 3c10 kpc, where the 3D model fit shows the rotating [C ii]-gas disk spread over 4 times larger than the rest-frame UV-emitting region. Galaxies with the extended [C ii] line structure have high star formation rate, high stellar mass (M star), low Ly\u3b1 equivalent width, and more blueshifted (redshifted) rest-frame UV metal absorption (Ly\u3b1 line), as compared to galaxies without such extended [C ii] structures. Although we cannot rule out the possibility that a selection bias toward luminous objects may be responsible for such trends, the star-formation-driven outflow also explains all these trends. Deeper observations are essential to test whether the extended [C ii] line structures are ubiquitous to high-z star-forming galaxies

ANTARES upper limits on the multi-TeV neutrino emission from the GRBs detected by IACTs

The first gamma-ray burst detections by Imaging Atmospheric Cherenkov Telescopes have been recently announced: GRB 190114C, detected by MAGIC, GRB 180720B and GRB 190829A, observed by H.E.S.S. A dedicated search for neutrinos in space and time coincidence with the gamma-ray emission observed by IACTs has been performed using ANTARES data. The search covers both the prompt and afterglow phases, yielding no neutrinos in coincidence with the three GRBs studied. Upper limits on the energetics of the neutrino emission are inferred. The resulting upper limits are several orders of magnitude above the observed gamma-ray emission, and they do not allow to constrain the available models