ONTOLOGIA E MEDIAÇÃO: KANT, PEIRCE E JUNG

The origins of this text are a result from the reflections accomplished in group, during the development of the disciplines “Epistemology and Science” and “Semiotics, Aesthetics and Knowledge”, both of the Post-Graduate Program in Knowledge Engineering and Management - UFSC. The main approached subject is the intuition in the knowledge origin, as it was proposed firstly in the categories presented in the "Critical of Pure Reason" of Immanuel Kant, which had questioned the cartesianism. Later, the Kantian categories were also criticized by Charles S. Peirce, that was author of a series of seven questions on the theme in study. Those questions are presented and discussed to follow, in accordance with the Peirce’s thought and, also, with Carl Gustav Jung ideas. The convergence point that justifies the confrontation of the Peirce and Jung ideas is the symbol concept that was adopted and particularly developed by the two thinkers.As origens deste texto decorrem das reflexões realizadas em grupo, durante o desenvolvimento das disciplinas “Epistemologia e Ciência” e “Semiótica, Estética e Conhecimento”, ambas do Programa de Pós-Graduação em Engenharia e Gestão do Conhecimento - UFSC. A principal questão abordada é a intuição na origem do conhecimento, como foi primeiramente proposta nas categorias apresentadas na “Crítica da Razão Pura” de Immanuel Kant, as quais questionaram o cartesianismo. Posteriormente, as categorias kantianas também foram criticadas por Charles S. Peirce, que foi autor de uma série de sete questões sobre o tema em estudo. Essas questões são apresentadas e discutidas a seguir, de acordo com o pensamento de Peirce e, também, com as idéias de Carl Gustav Jung. O ponto de convergência que justifica o confronto das idéias de Peirce e Jung é o conceito de símbolo que foi adotado e particularmente desenvolvido pelos dois pensadores

Tecnologias sociais: as organizações não governamentais no enfrentamento das mudanças climáticas e na promoção de desenvolvimento humano

De acordo com o quarto relatório do Intergovernmental Panel on Climate Change (IPCC), as regiões semiáridas do mundo estarão entre as mais afetadas pelos impactos das mudanças climáticas globais. Estudos realizados pelo Ministério do Meio Ambiente (MMA), em 2007, confirmam que, no Nordeste brasileiro, não apenas choverá menos e mais irregularmente, mas, também, haverá mais secas, devido ao aquecimento da temperatura. Diante dos diversos impactos sociais, ambientais e econômicos possíveis nesses cenários, é de fundamental importância a verificação de alternativas sustentáveis para o semiárido brasileiro. Este artigo tem por objetivo avaliar o potencial de algumas das tecnologias sociais (TS) de convivência com o semiárido, desenvolvidas por diversas organizações, para a mitigação das mudanças climáticas e a promoção de desenvolvimento humano. Constata-se que as TS tem grande potencial para auxiliar na mitigação e na adaptação das mudanças climáticas, ao mesmo tempo que promovem melhorias na qualidade de vida das localidades onde estão sendo desenvolvidas

The C-terminal region of Trypanosoma cruzi MASPs is antigenic and secreted via exovesicles.

Trypanosoma cruzi is the etiological agent of Chagas disease, a neglected and emerging tropical disease, endemic to South America and present in non-endemic regions due to human migration. The MASP multigene family is specific to T. cruzi, accounting for 6% of the parasite's genome and plays a key role in immune evasion. A common feature of MASPs is the presence of two conserved regions: an N-terminal region codifying for signal peptide and a C-terminal (C-term) region, which potentially acts as GPI-addition signal peptide. Our aim was the analysis of the presence of an immune response against the MASP C-term region. We found that this region is highly conserved, released via exovesicles (EVs) and has an associated immune response as revealed by epitope affinity mapping, IFA and inhibition of the complement lysis assays. We also demonstrate the presence of a fast IgM response in Balb/c mice infected with T. cruzi. Our results reveal the presence of non-canonical secreted peptides in EVs, which can subsequently be exposed to the immune system with a potential role in evading immune system targets in the parasite

The ocean sampling day consortium

Ocean Sampling Day was initiated by the EU-funded Micro B3 (Marine Microbial Biodiversity, Bioinformatics, Biotechnology) project to obtain a snapshot of the marine microbial biodiversity and function of the world’s oceans. It is a simultaneous global mega-sequencing campaign aiming to generate the largest standardized microbial data set in a single day. This will be achievable only through the coordinated efforts of an Ocean Sampling Day Consortium, supportive partnerships and networks between sites. This commentary outlines the establishment, function and aims of the Consortium and describes our vision for a sustainable study of marine microbial communities and their embedded functional traits

Constraints on the χ_(c1) versus χ_(c2) polarizations in proton-proton collisions at √s = 8 TeV

The polarizations of promptly produced χ_(c1) and χ_(c2) mesons are studied using data collected by the CMS experiment at the LHC, in proton-proton collisions at √s=8  TeV. The χ_c states are reconstructed via their radiative decays χ_c → J/ψγ, with the photons being measured through conversions to e⁺e⁻, which allows the two states to be well resolved. The polarizations are measured in the helicity frame, through the analysis of the χ_(c2) to χ_(c1) yield ratio as a function of the polar or azimuthal angle of the positive muon emitted in the J/ψ → μ⁺μ⁻ decay, in three bins of J/ψ transverse momentum. While no differences are seen between the two states in terms of azimuthal decay angle distributions, they are observed to have significantly different polar anisotropies. The measurement favors a scenario where at least one of the two states is strongly polarized along the helicity quantization axis, in agreement with nonrelativistic quantum chromodynamics predictions. This is the first measurement of significantly polarized quarkonia produced at high transverse momentum