1,166 research outputs found
Altering a Histone H3K4 Methylation Pathway in Glomerular Podocytes Promotes a Chronic Disease Phenotype
- Author
- B Genc
- B Schuettengruber
- BE Bernstein
- BL Wharram
- C Cho
- C El-Aouni
- C Faul
- D Appel
- D Kerjaschki
- D Kim
- D Kim
- D Kim
- DJ Salant
- Doyeob Kim
- E Ronconi
- EA Cho
- GA Blobel
- Gaelle M. Lefevre
- GK Smyth
- GL Cuthbert
- Gregory R. Dressler
- H Kurihara
- H Paves
- H Suleiman
- HL Zhang
- HL Zhang
- I Issaeva
- J Ho
- J Lee
- J Patrakka
- K Okita
- K Steger
- KH Campbell
- KH Hansen
- L Ringrose
- L Ringrose
- L Tessarollo
- L Tessarollo
- Lino Tessarollo
- M Fang
- M Wernig
- MJ Donovan
- MJ Moeller
- MJ Moeller
- MP Rastaldi
- MS Lechner
- P Chi
- P Soriano
- PD Gluckman
- R Margueron
- R Pabst
- R Verma
- RA Irizarry
- RC Wiggins
- S Glaser
- Sanjeevkumar R. Patel
- SL Berger
- SM Wykes
- SR Patel
- TA Milne
- V Castellani
- Veronica van Heyningen
- W Mu
- Y Benjamini
- YB Schwartz
- YW Cho
- YW Cho
- Publication venue
- Public Library of Science
- Publication date
- 01/10/2010
- Field of study
Methylation of specific lysine residues in core histone proteins is essential for embryonic development and can impart active and inactive epigenetic marks on chromatin domains. The ubiquitous nuclear protein PTIP is encoded by the Paxip1 gene and is an essential component of a histone H3 lysine 4 (H3K4) methyltransferase complex conserved in metazoans. In order to determine if PTIP and its associated complexes are necessary for maintaining stable gene expression patterns in a terminally differentiated, non-dividing cell, we conditionally deleted PTIP in glomerular podocytes in mice. Renal development and function were not impaired in young mice. However, older animals progressively exhibited proteinuria and podocyte ultra structural defects similar to chronic glomerular disease. Loss of PTIP resulted in subtle changes in gene expression patterns prior to the onset of a renal disease phenotype. Chromatin immunoprecipitation showed a loss of PTIP binding and lower H3K4 methylation at the Ntrk3 (neurotrophic tyrosine kinase receptor, type 3) locus, whose expression was significantly reduced and whose function may be essential for podocyte foot process patterning. These data demonstrate that alterations or mutations in an epigenetic regulatory pathway can alter the phenotypes of differentiated cells and lead to a chronic disease state
p-Adic Mathematical Physics
- Author
- A. Connes
- A. Connes
- A. Escassut
- A. Escassut
- A. Kh. Bikulov
- A. Kh. Bikulov
- A. N. Kochubei
- A. N. Kochubei
- A. N. Kochubei
- A. N. Kochubei
- A. N. Kochubei
- A. N. Kochubei
- A. N. Kochubei
- A. N. Kochubei
- A. N. Kochubei
- A. S. Koshelev
- A. Weil
- A. Yu. Khrennikov
- A. Yu. Khrennikov
- A. Yu. Khrennikov
- A. Yu. Khrennikov
- A. Yu. Khrennikov
- A. Yu. Khrennikov
- A. Yu. Khrennikov
- A. Yu. Khrennikov
- A. Yu. Khrennikov
- A. Yu. Khrennikov
- A. Yu. Khrennikov
- A. Yu. Khrennikov
- A. Yu. Khrennikov
- A. Yu. Khrennikov
- A. Yu. Khrennikov
- A. Yu. Khrennikov
- A. Yu. Khrennikov
- A. Yu. Khrennikov
- A. Yu. Khrennikov
- A. Yu. Khrennikov
- A. Yu. Khrennikov
- A. Yu. Khrennikov
- A. Yu. Khrennikov
- A. Yu. Khrennikov
- A. Yu. Khrennikov
- A. Yu. Khrennikov
- A. Yu. Khrennikov
- B. Dragovich
- B. Dragovich
- B. Dragovich
- B. Dragovich
- B. Dragovich
- B. Dragovich
- B. Dragovich
- B. Dragovich
- B. Dragovich
- B. Dragovich
- B. Dragovich
- B. Dragovich
- B. Dragovich
- B. Dragovich
- B. Dragovich
- C. Consani
- D. Dubischar
- D. Ghoshal
- D. K. Arrowsmith
- D. R. Lebedev
- E. I. Zelenov
- E. I. Zelenov
- E. I. Zelenov
- E. I. Zelenov
- E.M. Radyna
- F. Mukhamedov
- F. Murtagh
- F. Vivaldi
- G. Calcagni
- G. DjordjeviΔ
- G. DjordjeviΔ
- G. DjordjeviΔ
- G. K. Kalisch
- G. Parisi
- G. Parisi
- G. Rammal
- G. S. DjordjeviΔ
- H. Kaneko
- H. Kaneko
- H. Kaneko
- Harish-Chandra
- I. M. Gelfand
- I. V. Volovich
- I. V. Volovich
- I. V. Volovich
- I. V. Volovich
- I. V. Volovich
- I. V. Volovich
- I. Ya. Arefβeva
- I. Ya. Arefβeva
- I. Ya. Arefβeva
- I. Ya. Arefβeva
- I. Ya. Arefβeva
- I. Ya. Arefβeva
- I. Ya. Arefβeva
- I. Ya. Arefβeva
- I. Ya. Arefβeva
- I. Ya. Arefβeva
- I.Ya. Arefβeva
- I.Ya. Arefβeva
- J. Benois-Pineau
- J. J. Benedetto
- J. Q. Trelewicz
- J. Silverman
- K. Yasuda
- K. Yasuda
- L. Brekke
- L. Brekke
- L. Chekhov
- M. B. Green
- M. D. Missarov
- M. J. S. Haran
- M. L. Gorbachuk
- M. Mezard
- M. N. Khokhlova
- M. R. Herman
- N. Barnaby
- N. Barnaby
- N. Moeller
- N. N. Bogolyubov
- O. G. Smolyanov
- P. G. O. Freund
- P. G. O. Freund
- P. H. Frampton
- P. H. Frampton
- P. H. Frampton
- P. Schneider
- R. S. Ismagilov
- S. Albeverio
- S. Albeverio
- S. Albeverio
- S. Albeverio
- S. Albeverio
- S. Albeverio
- S. Albeverio
- S. Albeverio
- S. Albeverio
- S. Fischenko
- S. Haran
- S. N. Evans
- S. V. Kozyrev
- S. V. Kozyrev
- S. V. Kozyrev
- S. V. Kozyrev
- S. V. Kozyrev
- S. V. Kozyrev
- S. V. Kozyrev
- S.V. Kozyrev
- V. A. Avetisov
- V. A. Avetisov
- V. A. Avetisov
- V. A. Avetisov
- V. A. Smirnov
- V. Anashin
- V. Anashin
- V. Forini
- V. I. Arnold
- V. S. Anashin
- V. S. Anashin
- V. S. Varadarajan
- V. S. Varadarajan
- V. S. Varadarajan
- V. S. Vladimirov
- V. S. Vladimirov
- V. S. Vladimirov
- V. S. Vladimirov
- V. S. Vladimirov
- V. S. Vladimirov
- V. S. Vladimirov
- V. S. Vladimirov
- V. S. Vladimirov
- V. S. Vladimirov
- V. S. Vladimirov
- W. A. Zuniga-Galindo
- W. A. Zuniga-Galindo
- W. H. Schikhof
- Ya. I. Volovich
- Yu. I. Manin
- Publication venue
- 'Pleiades Publishing Ltd'
- Publication date
- 27/04/2009
- Field of study
A brief review of some selected topics in p-adic mathematical physics is
presented.Comment: 36 page
Fibrocytes are associated with vascular and parenchymal remodelling in patients with obliterative bronchiolitis
- Author
- A Andersson-Sjoland
- A Elssner
- A Moeller
- AL Mora
- AM Ramirez
- AN Husain
- AY Yu
- AZ Dudek
- C Hitchon
- C Ward
- CH Wang
- E Mbemba
- EP Trulock
- H Luckraz
- H Tanjore
- HK Holland
- I Darby
- I Hartlapp
- J Gauldie
- JJ Tomasek
- K Nihlberg
- KH Hofbauer
- KS Lee
- L Mori
- L Zheng
- M Ebina
- M Hoshino
- M Iwano
- M Schmidt
- P Staller
- R Bucala
- R Saunders
- RM Strieter
- S Baraldo
- SW Crawford
- TE Quan
- V Brocker
- Publication venue
- BioMed Central
- Publication date
- 01/01/2009
- Field of study
<p>Abstract</p> <p>Background</p> <p>The aim of the present study was to explore the occurrence of fibrocytes in tissue and to investigate whether the appearance of fibrocytes may be linked to structural changes of the parenchyme and vasculature in the lungs of patients with obliterative bronchiolitis (OB) following lung or bone marrow transplantation.</p> <p>Methods</p> <p>Identification of parenchyme, vasculature, and fibrocytes was done by histological methods in lung tissue from bone marrow or lung-transplanted patients with obliterative bronchiolitis, and from controls.</p> <p>Results</p> <p>The transplanted patients had significantly higher amounts of tissue in the alveolar parenchyme (46.5 Β± 17.6%) than the controls (21.7 Β± 7.6%) (p < 0.05). The patients also had significantly increased numbers of fibrocytes identified by CXCR4/prolyl4-hydroxylase, CD45R0/prolyl4-hydroxylase, and CD34/prolyl4-hydroxylase compared to the controls (p < 0.01). There was a correlation between the number of fibrocytes and the area of alveolar parenchyma; CXCR4/prolyl 4-hydroxylase (p < 0.01), CD45R0/prolyl 4-hydroxylase (p < 0.05) and CD34/prolyl 4-hydroxylase (p < 0.05). In the pulmonary vessels, there was an increase in the endothelial layer in patients (0.31 Β± 0.13%) relative to the controls (0.037 Β± 0.02%) (p < 0.01). There was a significant correlation between the number of fibrocytes and the total area of the endothelial layer CXCR4/prolyl 4-hydroxylase (p < 0.001), CD45R0/prolyl 4-hydroxylase (p < 0.001) and CD34/prolyl 4-hydroxylase (p < 0.01). The percent areas of the lumen of the vessels were significant (p < 0.001) enlarged in the patient with OB compared to the controls. There was also a correlation between total area of the lumen and number of fibrocytes, CXCR4/prolyl 4-hydroxylase (p < 0.01), CD45R0/prolyl 4-hydroxylase (p < 0.001) and CD34/prolyl 4-hydroxylase (p < 0.01).</p> <p>Conclusion</p> <p>Our results indicate that fibrocytes are associated with pathological remodelling processes in patients with OB and that tissue fibrocytes might be a useful biomarker in these processes.</p
The structure of quality systems is important to the process and outcome, an empirical study of 386 hospital departments in Sweden
- Author
- A Donabedian
- A Donabedian
- A Staines
- C Vincent
- D Amaratunga
- D Blumenthal
- D Blumenthal
- G Maguerez
- H Geboers
- HM Hearnshaw
- I HallstrΓΆm
- J Moeller
- J Ovretveit
- J Ovretveit
- JF Hair
- JM Grimshaw
- K JΓΆreskog
- KD Rigby
- KH Roberts
- KJ Hardy
- L Burnett
- LL Leape
- MA van Bokhoven
- MJ Treadwell
- P Douglas
- P François
- P Shekelle
- R Grol
- R Lilford
- R Ursprung
- Ragnar Westerling
- S Jackson
- SH Woolf
- ST Kunkel
- Stefan Kunkel
- Urban Rosenqvist
- Publication venue
- BioMed Central
- Publication date
- 01/01/2007
- Field of study
<p>Abstract</p> <p>Background</p> <p>Clinicians, nurses, and managers in hospitals are continuously confronted by new technologies and methods that require changes to working practice. Quality systems can help to manage change while maintaining a high quality of care. A new model of quality systems inspired by the works of Donabedian has three factors: structure (resources and administration), process (culture and professional co-operation), and outcome (competence development and goal achievement). The objectives of this study were to analyse whether structure, process, and outcome can be used to describe quality systems, to analyse whether these components are related, and to discuss implications.</p> <p>Methods</p> <p>A questionnaire was developed and sent to a random sample of 600 hospital departments in Sweden. The adjusted response rate was 75%. The data were analysed with confirmatory factor analysis and structural equation modeling in LISREL. This is to our knowledge the first large quantitative study that applies Donabedian's model to quality systems.</p> <p>Results</p> <p>The model with relationships between structure, process, and outcome was found to be a reasonable representation of quality systems at hospital departments (p = 0.095, indicating no significant differences between the model and the data set). Structure correlated strongly with process (0.72) and outcome (0.60). Given structure, process also correlated with outcome (0.20).</p> <p>Conclusion</p> <p>The model could be used to describe and evaluate single quality systems or to compare different quality systems. It could also be an aid to implement a systematic and evidence-based system for working with quality improvements in hospital departments.</p
Search for supersymmetric particles in scenarios with a gravitino LSP and stau NLSP
- Author
- Abreu P
- Adam W
- Adye T
- Adzic P
- Albrecht Z
- Alderweireld T
- Alekseev GD
- Alemany R
- Allmendinger T
- Allport PP
- Almehed S
- Amaldi U
- Amapane N
- Amato S
- Anassontzis EG
- Andersson P
- Andreazza A
- Andringa S
- Antilogus P
- Apel WD
- Arnoud Y
- Asman B
- Augustin JE
- Augustinus A
- Baillon P
- Ballestrero A
- Bambade P
- Barao F
- Barbiellini G
- Barbier R
- Bardin DY
- Barker G
- Baroncelli A
- Battaglia M
- Baubillier M
- Becks KH
- Begalli M
- Behrmann A
- Beilliere P
- Belokopytov Y
- Belous K
- Benekos NC
- Benvenuti AC
- Berat C
- Berggren M
- Bertrand D
- Besancon M
- Bilenky MS
- Bizouard MA
- Bloch D
- Blom HM
- Bonesini M
- Boonekamp M
- Booth PSL
- Borisov G
- Bosio C
- Botner O
- Boudinov E
- Bouquet B
- Bourdarios C
- Bowcock TJV
- Boyko I
- Bozovic I
- Bozzo M
- Bracko M
- Branchini P
- Brenner RA
- Bruckman P
- Brunet JM
- Bugge L
- Buran T
- Buschbeck B
- Buschmann P
- Caballero IG
- Cabrera S
- Caccia M
- Calvi M
- Camporesi T
- Canale V
- Carena F
- Carroll L
- Caso C
- Cattai A
- Cavallo FR
- Chabaud V
- Chapkin M
- Charpentier P
- Checchia P
- Chelkov GA
- Chierici R
- Chliapnikov P
- Chochula P
- Chorowicz V
- Chudoba J
- Cieslik K
- Collaboration DELPHI
- Collins P
- Contri R
- Cortina E
- Cosme G
- Cossutti F
- Costa M
- Crawley HB
- Crennell D
- Crepe S
- Crosetti G
- Czellar S
- Da Silva W
- Davenport M
- De Angelis A
- De Boer W
- De Clercq C
- De Lotto B
- De Min A
- De Paula L
- Della Ricca G
- Delpierre P
- Demaria N
- Di Ciaccio L
- Dijkstra H
- Dolbeau J
- Doroba K
- Dracos M
- Drees J
- Dris M
- Duperrin A
- Durand JD
- Eigen G
- Ekelof T
- Ekspong G
- Ellert M
- Elsing M
- Engel JP
- Fanourakis G
- Fassouliotis D
- Fayot J
- Feindt M
- Ferrer A
- Ferrer-Ribas E
- Ferro F
- Fichet S
- Firestone A
- Flagmeyer U
- Foeth H
- Fokitis E
- Fontanelli F
- Franek B
- Frodesen AG
- Fruhwirth R
- Fulda-Quenzer F
- Fuster J
- Galloni A
- Gamba D
- Gamblin S
- Gandelman M
- Garcia C
- Garcia SMI
- Gaspar C
- Gaspar M
- Gasparini U
- Gavillet P
- Gazis EN
- Gele D
- Geralis T
- Ghodbane N
- Gil I
- Gimenez MVC
- Glege F
- Gokieli R
- Golob B
- Gomez-Ceballos G
- Goncalves P
- Gopal G
- Gorn L
- Gouz Y
- Gracco V
- Grahl J
- Graziani E
- Gris P
- Grosdidier G
- Grzelak K
- Guy J
- Haag C
- Hahn F
- Hahn S
- Haider S
- Hallgren A
- Hamacher K
- Hansen J
- Harris FJ
- Hauler F
- Hedberg V
- Heising S
- Hernandez JJ
- Herquet P
- Herr H
- Hessing TL
- Heuser JM
- Higon E
- Holmgren SO
- Holt PJ
- Hoorelbeke S
- Houlden M
- Hrubec J
- Huber M
- Huet K
- Hughes GJ
- Hultqvist K
- Jackson JN
- Jacobsson R
- Jalocha P
- Janik R
- Jarlskog C
- Jarlskog G
- Jarry P
- Jean-Marie B
- Jeans D
- Johansson EK
- Jonsson P
- Joram C
- Juillot P
- Jungermann L
- Kapusta F
- Karafasoulis K
- Katsanevas S
- Katsoufis EC
- Keranen R
- Kernel G
- Kersevan BP
- Khokhlov Y
- Khomenko BA
- Khovanski NN
- Kiiskinen A
- King B
- Kinvig A
- Kjaer NJ
- Klapp O
- Klein H
- Kluit P
- Kokkinias P
- Kostioukhine V
- Kourkoumelis C
- Kouznetsov O
- Krammer M
- Kriznic E
- Krumstein Z
- Kubinec P
- Kurowska J
- Kurvinen K
- Lamsa JW
- Lane DW
- Lapin V
- Laugier JP
- Lauhakangas R
- Leder G
- Ledroit F
- Lefebure V
- Leinonen L
- Leisos A
- Leitner R
- Lenzen G
- Lepeltier V
- Lesiak T
- Lethuillier M
- Libby J
- Liebig W
- Liko D
- Lipniacka A
- Lippi I
- Loerstad B
- Loken JG
- Lopes JH
- Lopez JM
- Lopez-Fernandez R
- Loukas D
- Lutz P
- Lyons L
- MacNaughton J
- Maestro JC
- Mahon JR
- Maio A
- Malek A
- Malmgren TGM
- Maltezos S
- Malychev V
- Mandl F
- Marco J
- Marco R
- Marechal B
- Margoni M
- Marin JC
- Mariotti C
- Markou A
- Martinez-Rivero C
- Masik J
- Mastroyiannopoulos N
- Matorras F
- Matteuzzi C
- Matthiae G
- Mazzucato F
- Mazzucato M
- McCubbin M
- McKay R
- McNulty R
- McPherson G
- Meroni C
- Meyer WT
- Miagkov A
- Migliore E
- Mirabito L
- Mitaroff WA
- Mjoernmark U
- Moa T
- Moch M
- Moeller R
- Moenig K
- Monge MR
- Moraes D
- Moreau X
- Morettini P
- Morton G
- Mueller U
- Muenich K
- Mulders M
- Mulet-Marquis C
- Muresan R
- Murray WJ
- Muryn B
- Myatt G
- Myklebust T
- Naraghi F
- Nassiakou M
- Navarria FL
- Nawrocki K
- Negri P
- Neufeld N
- Nicolaidou R
- Nielsen BS
- Niezurawski P
- Nikolenko M
- Nomokonov V
- Nygren A
- Obraztsov V
- Olshevski AG
- Onofre A
- Orava R
- Orazi G
- Osterberg K
- Ouraou A
- Oyanguren A
- Paganoni M
- Paiano S
- Pain R
- Paiva R
- Palacios J
- Palka H
- Papadopoulou TD
- Pape L
- Parkes C
- Parodi F
- Parzefall U
- Passeri A
- Passon O
- Pavel T
- Pegoraro M
- Peralta L
- Pernicka M
- Perrotta A
- Petridou C
- Petrolini A
- Phillips HT
- Pierre F
- Pimenta M
- Piotto E
- Podobnik T
- Pol ME
- Polok G
- Poropat P
- Pozdniakov V
- Privitera P
- Pukhaeva N
- Pullia A
- Radojicic D
- Ragazzi S
- Rahmani H
- Rames J
- Ratoff PN
- Read AL
- Rebecchi P
- Redaelli NG
- Regler M
- Rehn J
- Reid D
- Reinertsen P
- Reinhardt R
- Renton PB
- Resvanis LK
- Richard F
- Ridky J
- Rinaudo G
- Ripp-Baudot I
- Rohne O
- Romero A
- Ronchese P
- Rosenberg EI
- Rosinsky P
- Roudeau P
- Rovelli T
- Royon C
- Ruhlmann-Kleider V
- Ruiz A
- Saarikko H
- Sacquin Y
- Sadovsky A
- Sajot G
- Salt J
- Sampsonidis D
- Sannino M
- Santo ME
- Schwemling P
- Schwering B
- Schwickerath U
- Scuri F
- Seager P
- Sedykh Y
- Segar AM
- Seibert N
- Sekulin R
- Shellard RC
- Siebel M
- Simard L
- Simonetto F
- Sisakian AN
- Smadja G
- Smirnova O
- Smith GR
- Solovianov O
- Sopczak A
- Sosnowski R
- Spassov T
- Spiriti E
- Squarcia S
- Stanescu C
- Stanic S
- Stanitzki M
- Stevenson K
- Stocchi A
- Strauss J
- Strub R
- Stugu B
- Szczekowski M
- Szeptycka M
- Tabarelli T
- Taffard A
- Tegenfeldt F
- Terranova F
- Thomas J
- Timmermans J
- Tinti N
- Tkatchev LG
- Tobin M
- Todorova S
- Tomaradze A
- Tome B
- Tonazzo A
- Tortora L
- Tortosa P
- Transtromer G
- Treille D
- Tristram G
- Trochimczuk M
- Troncon C
- Turluer ML
- Tyapkin IA
- Tyapkin P
- Tzamarias S
- Ullaland O
- Uvarov V
- Valenti G
- Vallazza E
- Van Dam P
- Van den Boeck W
- Van Eldik J
- Van Lysebetten A
- van Remortel N
- Van Vulpen I
- Vegni G
- Ventura L
- Venus W
- Verbeure F
- Verdier P
- Verlato M
- Vertogradov LS
- Verzi V
- Vilanova D
- Vitale L
- Vlasov E
- Vodopyanov AS
- Voulgaris G
- Vrba V
- Wahlen H
- Walck C
- Washbrook AJ
- Weiser C
- Wicke D
- Wickens JH
- Wilkinson GR
- Winter M
- Witek M
- Wolf G
- Yi J
- Yushchenko O
- Zalewska A
- Zalewski P
- Zavrtanik D
- Zevgolatakos E
- Zimin NI
- Zintchenko A
- Zoller P
- Zucchelli GC
- Zumerle G
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2000
- Field of study
Sleptons, neutralinos and charginos were searched for in the context of
scenarios where the lightest supersymmetric particle is the gravitino. It was
assumed that the stau is the next-to-lightest supersymmetric particle. Data
collected with the DELPHI detector at a centre-of-mass energy near 189 GeV were
analysed combining the methods developed in previous searches at lower
energies. No evidence for the production of these supersymmetric particles was
found. Hence, limits were derived at 95% confidence level.Comment: 31 pages, 14 figure
Performance of CMS muon reconstruction in pp collision events at sqrt(s) = 7 TeV
- Author
- Abbaneo D
- Abbiendi G
- Abbrescia M
- Abdullin S
- Acosta D
- Acosta JG
- Acosta MV
- Adair A
- Adam N
- Adam W
- Adams MR
- Adams T
- Adiguzel A
- Adler V
- Adzic P
- Agostino L
- Agram JL
- Aguilar-Benitez M
- Aguilo E
- Ahmad M
- Ahmad WH
- Ahuja S
- Akchurin N
- Akgun B
- Akgun U
- Akin IV
- Alagoz E
- Albajar C
- Albayrak EA
- Albergo S
- Albrow M
- Alda Junior WL
- Alexander J
- Aliev T
- Almeida N
- Alver B
- Alverson G
- Alves GA
- Amapane N
- Amsler C
- Anagnostou G
- Anastassov A
- Anderson J
- Anderson M
- Andrea J
- Andreev V
- Andreev V
- Andreev Y
- Andrews W
- Anghel IM
- Anjos TS
- Antonelli L
- Antunes JR
- Antunovic Z
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- Xiao H
- Xie S
- Xu M
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- Yang F
- Yang M
- Yang Y
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- Yazgan E
- Yelton J
- Yetkin T
- Yi K
- Yildirim E
- Yilmaz Y
- Yohay R
- Yoo HD
- Yoo J
- Yoon AS
- York A
- Yu I
- Yu SS
- Yumiceva F
- Yun JC
- Zabel J
- Zabi A
- Zablocki J
- Zaganidis N
- Zakaria M
- Zalewski P
- Zanetti M
- Zang J
- Zang SL
- Zarubin A
- Zatserklyaniy A
- Zeinali M
- Zeise M
- Zeuner WD
- Zeyrek M
- Zhang J
- Zhang Z
- Zheng Y
- Zhokin A
- Zhu B
- Zhu RY
- Zhukov V
- Zhukova V
- Ziebarth EB
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- Zoeller MH
- Zotto P
- Zou W
- Zumerle G
- Zuranski A
- Publication venue
- 'IOP Publishing'
- Publication date
- 01/01/2012
- Field of study
The performance of muon reconstruction, identification, and triggering in CMS
has been studied using 40 inverse picobarns of data collected in pp collisions
at sqrt(s) = 7 TeV at the LHC in 2010. A few benchmark sets of selection
criteria covering a wide range of physics analysis needs have been examined.
For all considered selections, the efficiency to reconstruct and identify a
muon with a transverse momentum pT larger than a few GeV is above 95% over the
whole region of pseudorapidity covered by the CMS muon system, abs(eta) < 2.4,
while the probability to misidentify a hadron as a muon is well below 1%. The
efficiency to trigger on single muons with pT above a few GeV is higher than
90% over the full eta range, and typically substantially better. The overall
momentum scale is measured to a precision of 0.2% with muons from Z decays. The
transverse momentum resolution varies from 1% to 6% depending on pseudorapidity
for muons with pT below 100 GeV and, using cosmic rays, it is shown to be
better than 10% in the central region up to pT = 1 TeV. Observed distributions
of all quantities are well reproduced by the Monte Carlo simulation.Comment: Replaced with published version. Added journal reference and DO
Performance of CMS muon reconstruction in pp collision events at sqrt(s) = 7 TeV
- Author
- Abbaneo D
- Abbiendi G
- Abbrescia M
- Abdullin S
- Acosta D
- Acosta JG
- Acosta MV
- Adair A
- Adam N
- Adam W
- Adams MR
- Adams T
- Adiguzel A
- Adler V
- Adzic P
- Agostino L
- Agram JL
- Aguilar-Benitez M
- Aguilo E
- Ahmad M
- Ahmad WH
- Ahuja S
- Akchurin N
- Akgun B
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- Akin IV
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- Albayrak EA
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- Alexander J
- Aliev T
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- Alverson G
- Alves GA
- Amapane N
- Amsler C
- Anagnostou G
- Anastassov A
- Anderson J
- Anderson M
- Andrea J
- Andreev V
- Andreev V
- Andreev Y
- Andrews W
- Anghel IM
- Anjos TS
- Antonelli L
- Antunes JR
- Antunovic Z
- Apanasevich L
- Apollinari G
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- Azhgirey I
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- Bauerdick LAT
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- Xiao H
- Xie S
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- Yang M
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- Yazgan E
- Yelton J
- Yetkin T
- Yi K
- Yildirim E
- Yilmaz Y
- Yohay R
- Yoo HD
- Yoo J
- Yoon AS
- York A
- Yu I
- Yu SS
- Yumiceva F
- Yun JC
- Zabel J
- Zabi A
- Zablocki J
- Zaganidis N
- Zakaria M
- Zalewski P
- Zanetti M
- Zang J
- Zang SL
- Zarubin A
- Zatserklyaniy A
- Zeinali M
- Zeise M
- Zeuner WD
- Zeyrek M
- Zhang J
- Zhang Z
- Zheng Y
- Zhokin A
- Zhu B
- Zhu RY
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- Zoeller MH
- Zotto P
- Zou W
- Zumerle G
- Zuranski A
- Publication venue
- 'IOP Publishing'
- Publication date
- 01/01/2012
- Field of study
The performance of muon reconstruction, identification, and triggering in CMS
has been studied using 40 inverse picobarns of data collected in pp collisions
at sqrt(s) = 7 TeV at the LHC in 2010. A few benchmark sets of selection
criteria covering a wide range of physics analysis needs have been examined.
For all considered selections, the efficiency to reconstruct and identify a
muon with a transverse momentum pT larger than a few GeV is above 95% over the
whole region of pseudorapidity covered by the CMS muon system, abs(eta) < 2.4,
while the probability to misidentify a hadron as a muon is well below 1%. The
efficiency to trigger on single muons with pT above a few GeV is higher than
90% over the full eta range, and typically substantially better. The overall
momentum scale is measured to a precision of 0.2% with muons from Z decays. The
transverse momentum resolution varies from 1% to 6% depending on pseudorapidity
for muons with pT below 100 GeV and, using cosmic rays, it is shown to be
better than 10% in the central region up to pT = 1 TeV. Observed distributions
of all quantities are well reproduced by the Monte Carlo simulation.Comment: Replaced with published version. Added journal reference and DO
X-ray emission from the Sombrero galaxy: discrete sources
- Author
- Abbaneo D
- Abbiendi G
- Abbrescia M
- Abdullin S
- Acosta D
- Acosta JG
- Acosta MV
- Adam N
- Adam W
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- Adiguzel A
- Adler V
- Adzic P
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- Agram JL
- Aguilar-Benitez M
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- Ahmad M
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- Andreev Y
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- Publication venue
- 'IOP Publishing'
- Publication date
- 01/01/2010
- Field of study
We present a study of discrete X-ray sources in and around the
bulge-dominated, massive Sa galaxy, Sombrero (M104), based on new and archival
Chandra observations with a total exposure of ~200 ks. With a detection limit
of L_X = 1E37 erg/s and a field of view covering a galactocentric radius of ~30
kpc (11.5 arcminute), 383 sources are detected. Cross-correlation with Spitler
et al.'s catalogue of Sombrero globular clusters (GCs) identified from HST/ACS
observations reveals 41 X-rays sources in GCs, presumably low-mass X-ray
binaries (LMXBs). We quantify the differential luminosity functions (LFs) for
both the detected GC and field LMXBs, whose power-low indices (~1.1 for the
GC-LF and ~1.6 for field-LF) are consistent with previous studies for
elliptical galaxies. With precise sky positions of the GCs without a detected
X-ray source, we further quantify, through a fluctuation analysis, the GC LF at
fainter luminosities down to 1E35 erg/s. The derived index rules out a
faint-end slope flatter than 1.1 at a 2 sigma significance, contrary to recent
findings in several elliptical galaxies and the bulge of M31. On the other
hand, the 2-6 keV unresolved emission places a tight constraint on the field
LF, implying a flattened index of ~1.0 below 1E37 erg/s. We also detect 101
sources in the halo of Sombrero. The presence of these sources cannot be
interpreted as galactic LMXBs whose spatial distribution empirically follows
the starlight. Their number is also higher than the expected number of cosmic
AGNs (52+/-11 [1 sigma]) whose surface density is constrained by deep X-ray
surveys. We suggest that either the cosmic X-ray background is unusually high
in the direction of Sombrero, or a distinct population of X-ray sources is
present in the halo of Sombrero.Comment: 11 figures, 5 tables, ApJ in pres
Azimuthal anisotropy of charged particles at high transverse momenta in PbPb collisions at sqrt(s[NN]) = 2.76 TeV
- Author
- Abbaneo D
- Abbiendi G
- Abbrescia M
- Abdullin S
- Abdulsalam A
- Acosta D
- Acosta JG
- Acosta MV
- Adair A
- Adam N
- Adam W
- Adams MR
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- Adiguzel A
- Adler V
- Adzic P
- Afanasiev S
- Agostino L
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- Aguilar-Benitez M
- Aguilo E
- Ahmad M
- Ahmad WH
- Ahuja S
- Akchurin N
- Akgun B
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- Akin IV
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- Civinini C
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- CMS Collaboration
- Coarasa Perez JA
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- Cooper SI
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- Cutajar M
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- Yi K
- Yildirim E
- Yilmaz Y
- Yohay R
- Yoo HD
- Yoo J
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- Yumiceva F
- Yun JC
- Zabel J
- Zabi A
- Zablocki J
- Zaganidis N
- Zakaria M
- Zalewski P
- Zanetti M
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- Zarubin A
- Zatserklyaniy A
- Zeinali M
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- Zeuner WD
- Zeyrek M
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- Zhukov V
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- Zumerle G
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- Publication venue
- 'American Physical Society (APS)'
- Publication date
- 01/01/2012
- Field of study
The azimuthal anisotropy of charged particles in PbPb collisions at
nucleon-nucleon center-of-mass energy of 2.76 TeV is measured with the CMS
detector at the LHC over an extended transverse momentum (pt) range up to
approximately 60 GeV. The data cover both the low-pt region associated with
hydrodynamic flow phenomena and the high-pt region where the anisotropies may
reflect the path-length dependence of parton energy loss in the created medium.
The anisotropy parameter (v2) of the particles is extracted by correlating
charged tracks with respect to the event-plane reconstructed by using the
energy deposited in forward-angle calorimeters. For the six bins of collision
centrality studied, spanning the range of 0-60% most-central events, the
observed v2 values are found to first increase with pt, reaching a maximum
around pt = 3 GeV, and then to gradually decrease to almost zero, with the
decline persisting up to at least pt = 40 GeV over the full centrality range
measured.Comment: Replaced with published version. Added journal reference and DO
Jet energy measurement with the ATLAS detector in proton-proton collisions at root s=7 TeV
- Author
- Aad G
- Abbott B
- Abdallah J
- Abdelalim AA
- Abdesselam A
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- Abramowicz H
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- Adomeit S
- Adragna P
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- Aguilar-Saavedra JA
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- Ahmad A
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- Aielli G
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- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/03/2013
- Field of study
The jet energy scale and its systematic uncertainty are determined for jets measured with the ATLAS detector at the LHC in proton-proton collision data at a centre-of-mass energy of βs = 7TeV corresponding to an integrated luminosity of 38 pb-1. Jets are reconstructed with the anti-kt algorithm with distance parameters R=0. 4 or R=0. 6. Jet energy and angle corrections are determined from Monte Carlo simulations to calibrate jets with transverse momenta pTβ₯20 GeV and pseudorapidities {pipe}Ξ·{pipe}<4. 5. The jet energy systematic uncertainty is estimated using the single isolated hadron response measured in situ and in test-beams, exploiting the transverse momentum balance between central and forward jets in events with dijet topologies and studying systematic variations in Monte Carlo simulations. The jet energy uncertainty is less than 2. 5 % in the central calorimeter region ({pipe}Ξ·{pipe}<0. 8) for jets with 60β€pT<800 GeV, and is maximally 14 % for pT<30 GeV in the most forward region 3. 2β€{pipe}Ξ·{pipe}<4. 5. The jet energy is validated for jet transverse momenta up to 1 TeV to the level of a few percent using several in situ techniques by comparing a well-known reference such as the recoiling photon pT, the sum of the transverse momenta of tracks associated to the jet, or a system of low-pT jets recoiling against a high-pT jet. More sophisticated jet calibration schemes are presented based on calorimeter cell energy density weighting or hadronic properties of jets, aiming for an improved jet energy resolution and a reduced flavour dependence of the jet response. The systematic uncertainty of the jet energy determined from a combination of in situ techniques is consistent with the one derived from single hadron response measurements over a wide kinematic range. The nominal corrections and uncertainties are derived for isolated jets in an inclusive sample of high-pT jets. Special cases such as event topologies with close-by jets, or selections of samples with an enhanced content of jets originating from light quarks, heavy quarks or gluons are also discussed and the corresponding uncertainties are determined. Β© 2013 CERN for the benefit of the ATLAS collaboration
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